Most cited papers in Inflammasome and immune disorders
What are the most cited papers in Inflammasome and immune disorders?
The most cited paper in Inflammasome and immune disorders is "Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease" (Paul M. Ridker et al., 2017), with 9,517 citations. Next come "Pattern Recognition Receptors and Inflammation" (8,914) and "Inflammation, Atherosclerosis, and Coronary Artery Disease" (8,822).
Showing 50 of 99 papers. Every paper with more than 1,915 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease Paul M. Ridker et al. · New England Journal of Medicine | 27 Aug 2017 | 9,517 |
| 2 | Pattern Recognition Receptors and Inflammation Osamu Takeuchi, Shizuo Akira · Cell | Mar 2010 | 8,914 |
| 3 | Inflammation, Atherosclerosis, and Coronary Artery Disease Göran K. Hansson · New England Journal of Medicine | 20 Apr 2005 | 8,822 |
| 4 | NF-κB signaling in inflammation Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy | 14 Jul 2017 | 8,517 |
| 5 | Inflammation and cancer: back to Virchow? Frances R. Balkwill, Alberto Mantovani · The Lancet | Feb 2001 | 7,766 |
| 6 | Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature | 16 Sep 2015 | 6,817 |
| 7 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Lorenzo Galluzzi et al. · Cell Death and Differentiation | 23 Jan 2018 | 6,760 |
| 8 | Origin and physiological roles of inflammation Ruslan M. Medzhitov · Nature | Jul 2008 | 6,592 |
| 9 | The Inflammasome Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell | Aug 2002 | 6,126 |
| 10 | A role for mitochondria in NLRP3 inflammasome activation Rongbin Zhou, Amir Sadegh Yazdi, Philippe Menu et al. · Nature | Dec 2010 | 5,609 |
| 11 | The Inflammasomes Kate Schroder, Jürg Tschopp · Cell | Mar 2010 | 5,489 |
| 12 | Gout-associated uric acid crystals activate the NALP3 inflammasome Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature | 11 Jan 2006 | 5,341 |
| 13 | Inflammatory responses and inflammation-associated diseases in organs Linlin Chen, Huidan Deng, Hengmin Cui et al. · Oncotarget | 14 Dec 2017 | 5,185 |
| 14 | Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science | 21 Dec 2012 | 5,027 |
| 15 | The NLRP3 inflammasome: molecular activation and regulation to therapeutics Karen V. Swanson, Meng Deng, Jenny P.‐Y. Ting · Nature reviews. Immunology | 29 Apr 2019 | 4,877 |
| 16 | Biologic basis for interleukin-1 in disease CA Dinarello · Blood | 15 Mar 1996 | 4,380 |
| 17 | NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature | Apr 2010 | 4,042 |
| 18 | Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases Claudio Franceschi, J. Campisi · The Journals of Gerontology Series A | 14 May 2014 | 3,937 |
| 19 | Inflammation and Cancer: Triggers, Mechanisms, and Consequences Florian R. Greten, Sergei I. Grivennikov · Immunity | Jul 2019 | 3,881 |
| 20 | Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling Nobuhiko Kayagaki et al. · Nature | 16 Sep 2015 | 3,790 |
| 21 | Inflammation in Atherosclerosis Peter Libby · Arteriosclerosis Thrombosis and Vascular Biology | 15 Aug 2012 | 3,754 |
| 22 | Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty Luigi Ferrucci, Elisa Fabbri · Nature Reviews Cardiology | 31 Jul 2018 | 3,731 |
| 23 | Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity Taro Kawai, Shizuo Akira · Immunity | May 2011 | 3,682 |
| 24 | STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling Hiroki Ishikawa, Glen N. Barber · Nature | 24 Aug 2008 | 3,591 |
| 25 | The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation Nathan Kelley, Devon Jeltema, Yanhui Duan et al. · International Journal of Molecular Sciences | 6 Jul 2019 | 3,586 |
| 26 | Inflammasomes: mechanism of assembly, regulation and signalling Petr Brož, Vishva M. Dixit · Nature reviews. Immunology | 13 Jun 2016 | 3,561 |
| 27 | Immunological and Inflammatory Functions of the Interleukin-1 Family Charles Anthony Dinarello · Annual Review of Immunology | 20 Mar 2009 | 3,501 |
| 28 | Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression Masahiro Nezu, Norio Suzuki, Masayuki P. Yamamoto · American Journal of Nephrology | 2017 | 3,459 |
| 29 | Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores Xing Liu, Zhibin Zhang, Jianbin Ruan et al. · Nature | 5 Jul 2016 | 3,316 |
| 30 | Pyroptosis: host cell death and inflammation Tessa Bergsbaken, Susan L. Fink, Brad T. Cookson · Nature Reviews Microbiology | 16 Jan 2009 | 3,313 |
| 31 | Inflammasomes: mechanism of action, role in disease, and therapeutics Haitao Guo, Justin Callaway, Jenny P.-Y. Ting · Nature Medicine | 29 Jun 2015 | 3,293 |
| 32 | Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature | 28 Apr 2017 | 3,284 |
| 33 | Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death Jianjin Shi, Wenqing Gao, Feng Shao · Trends in Biochemical Sciences | 5 Dec 2016 | 3,222 |
| 34 | Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation | 15 Feb 1998 | 3,183 |
| 35 | Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction Jean‐Claude Tardif et al. · New England Journal of Medicine | 16 Nov 2019 | 3,135 |
| 36 | Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses Trine Hyrup Mogensen · Clinical Microbiology Reviews | Apr 2009 | 3,124 |
| 37 | Cryopyrin activates the inflammasome in response to toxins and ATP Sanjeev Mariathasan, David S. Weiss, Kim I. Newton et al. · Nature | 11 Jan 2006 | 3,104 |
| 38 | Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Veit Hornung, Franz Georg Bauernfeind, Annett Halle et al. · Nature Immunology | 6 Jul 2008 | 3,083 |
| 39 | Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Kiichi Nakahira, Jeffrey A. Haspel, Vijay A. K. Rathinam et al. · Nature Immunology | 12 Dec 2010 | 3,055 |
| 40 | Sterile inflammation: sensing and reacting to damage Grace Chen, Gabriel Núñez · Nature reviews. Immunology | 19 Nov 2010 | 3,052 |
| 41 | Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression Franz Georg Bauernfeind, Gabor L Horvath, Andrea Stutz et al. · The Journal of Immunology | Jul 2009 | 2,990 |
| 42 | NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice Michael Thomas Heneka, Markus P. Kummer, Andrea Stutz et al. · Nature | 18 Dec 2012 | 2,957 |
| 43 | Activation and regulation of the inflammasomes Eicke Latz, Tsan Sam Xiao, Andrea Stutz · Nature reviews. Immunology | 24 May 2013 | 2,928 |
| 44 | Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability Francesco Colotta, Paola Allavena, Antonio Sica et al. · Carcinogenesis | 25 May 2009 | 2,919 |
| 45 | A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases Rebecca C. Coll et al. · Nature Medicine | 16 Feb 2015 | 2,894 |
| 46 | Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Thomas G Wegmann, Hui Lin, Larry J. Guilbert et al. · Immunology Today | Jul 1993 | 2,880 |
| 47 | Pore-forming activity and structural autoinhibition of the gasdermin family Jingjin Ding, Kun Wang, Wang Liu et al. · Nature | 7 Jun 2016 | 2,855 |
| 48 | Mechanism and Regulation of NLRP3 Inflammasome Activation Yuan He, Hideki Hara, Gabriel Núñez · Trends in Biochemical Sciences | 24 Sep 2016 | 2,794 |
| 49 | STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature | 23 Sep 2009 | 2,791 |
| 50 | Points of control in inflammation Carl Nathan · Nature | Dec 2002 | 2,740 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.