Science Explorer Back to mapMap
Discussion
Topic · Molecular Biology

Inflammasome and immune disorders

Inflammasome and immune disorders is a research topic within Molecular Biology. Science Explorer counts 26k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the molecular mechanisms of inflammasome activation, regulation, and its role in inflammatory responses, cell death (pyroptosis), and immune-related diseases. It covers topics such as NLRP3 inflammasome, interleukin-1, caspase-1, and the involvement of mitochondria in inflammasome activation.

  • Inflammasome
  • NLRP3
  • Pyroptosis
  • Interleukin-1
  • Caspase-1
  • Inflammation
  • Cell Death
  • Immune Response
  • Mitochondria
  • Autoinflammatory Diseases
Research works
26k
fractional, since 1950
In the world top 10%
2.6k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+47%
the tick is no change
Largest producer
China
61% of the 10 largest, 2022-now
Inflammasome and immune disorders

Which countries lead Inflammasome and immune disorders research?

By volume, China and the United States publish the most (4.9k and 1.2k works in 2022-now).

By volume, 2022-now

  1. 1 China 4.9k works
  2. 2 United States 1.2k works
  3. 3 Türkiye 330 works
  4. 4 India 276 works
  5. 5 Germany 274 works
  6. 6 Italy 237 works
  7. 7 Japan 236 works
  8. 8 South Korea 188 works
  9. 9 United Kingdom 186 works
  10. 10 France 175 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 61.2%United States: 14.9%Türkiye: 4.1%India: 3.5%6 others listed: 16.3%61%largest
China4,866 · 61.2%United States1,185 · 14.9%Türkiye330 · 4.1%India276 · 3.5%6 others listed1,296 · 16.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Inflammasome and immune disorders research?

By volume in 2022-now, Shanghai Jiao Tong University publishes the most Inflammasome and immune disorders research, followed by Sun Yat-sen University and Nanjing Medical University.

By volume, 2022-now

  1. 1 Shanghai Jiao Tong UniversityChina 96 works
  2. 2 Sun Yat-sen UniversityChina 95 works
  3. 3 Nanjing Medical UniversityChina 90 works
  4. 4 Central South UniversityChina 90 works
  5. 5 Zhejiang UniversityChina 83 works
  6. 6 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 76 works
  7. 7 Sichuan UniversityChina 76 works
  8. 8 Southern Medical UniversityChina 74 works
  9. 9 Wuhan UniversityChina 74 works
  10. 10 Fudan UniversityChina 73 works

Who are the leading researchers in Inflammasome and immune disorders?

The most-cited researchers publishing on Inflammasome and immune disorders include George Davey Smith, Guido Kroemer and John J.V. McMurray.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Guido Kroemer France 386k citations
  3. 3 John J.V. McMurray United Kingdom 349k citations
  4. 4 Hermann Brenner Germany 343k citations
  5. 5 Shizuo Akira Japan 342k citations
  6. 6 Emelia J. Benjamin United States 341k citations
  7. 7 Jun Wang China 340k citations
  8. 8 Graeme J. Hankey Australia 316k citations
  9. 9 Gregory Y.H. Lip United Kingdom 311k citations
  10. 10 Gonçalo R. Abecasis United States 300k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Inflammasome and immune disorders?

The most cited paper in Inflammasome and immune disorders is "Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease" (Paul M. Ridker et al., 2017), with 9,517 citations. Next come "Pattern Recognition Receptors and Inflammation" (8,914) and "Inflammation, Atherosclerosis, and Coronary Artery Disease" (8,822).

Most cited papers
#PaperReleasedCitations
1 Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease Paul M. Ridker et al. · New England Journal of Medicine Open access 27 Aug 2017 9,517
2 Pattern Recognition Receptors and Inflammation Osamu Takeuchi, Shizuo Akira · Cell Open access Mar 2010 8,914
3 Inflammation, Atherosclerosis, and Coronary Artery Disease Göran K. Hansson · New England Journal of Medicine 20 Apr 2005 8,822
4 NF-κB signaling in inflammation Ting Liu, Lingyun Zhang, Donghyun Joo et al. · Signal Transduction and Targeted Therapy Open access 14 Jul 2017 8,517
5 Inflammation and cancer: back to Virchow? Frances R. Balkwill, Alberto Mantovani · The Lancet Feb 2001 7,766
All 99 most cited papers, with filters and sorting

Where is Inflammasome and immune disorders research done?

The largest centres of Inflammasome and immune disorders research in 2022-now are Beijing (China), Guangzhou (China), Shanghai (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Luzhou, Zunyi and Hengyang.

Largest cities, 2022-now

  1. 1 BeijingChina 450 works
  2. 2 GuangzhouChina 346 works
  3. 3 ShanghaiChina 341 works
  4. 4 NanjingChina 229 works
  5. 5 WuhanChina 199 works
  6. 6 HangzhouChina 176 works
  7. 7 ChangshaChina 175 works
  8. 8 ChengduChina 154 works
  9. 9 JinanChina 132 works
  10. 10 HefeiChina 125 works

Where it is the local speciality

  1. LuzhouCN · 31.7 works13×
  2. ZunyiCN · 25.8 works13×
  3. HengyangCN · 33.3 works9.7×
  4. WenzhouCN · 74.8 works8.8×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Inflammasome and immune disorders than the world average.

See Inflammasome and immune disorders on the map

Where is the best place to study Inflammasome and immune disorders?

Among universities, judged by research, Harvard University, Sun Yat-sen University and Wuhan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 14.97%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityWuhan UniversitySun Yat-sen UniversityCentral South Univer…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 72.520.3%2.4×65 +1.8%
2Sun Yat-sen UniversityChina 71.515.2%5.4×95 +70.4%
3Wuhan UniversityChina 70.216.0%6.2×74 +75.0%
4Central South UniversityChina 69.514.1%5.5×90 +82.1%
5Shanghai Jiao Tong UniversityChina 67.713.7%3.9×96 +50.4%
6Sichuan UniversityChina 67.116.6%4.0×76 +159.1%
7Southern Medical UniversityChina 67.012.5%14.1×74 +88.9%
8Wenzhou Medical UniversityChina 66.814.0%16.0×68 +116.1%
9Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 66.613.3%8.5×76 +95.9%
10Zhejiang UniversityChina 65.714.0%3.6×83 +116.0%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Inflammasome and immune disorders, country by country

Is Inflammasome and immune disorders research growing?

Output in 2022-2025 was 47% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Inflammasome and immune disorders.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Inflammasome and immune disorders as a percentage of every work published that year, 0.039% in 2024.

still counting0.020%0.040%0.060%Inflammasome and immune disorders0.041% in 202519801990200020102020

Fractional works of Inflammasome and immune disorders over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Inflammasome and immune disorders9.7% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

Ask a question or share a note about Inflammasome and immune disorders. Posts are plain text and can be reported.