Topic · Iron Metabolism and Disorders
Most cited papers in Iron Metabolism and Disorders
What are the most cited papers in Iron Metabolism and Disorders?
The most cited paper in Iron Metabolism and Disorders is "The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay" (Iris F. F. Benzie, JJ Strain, 1996), with 23,032 citations. Next come "Maternal and child undernutrition: global and regional exposures and health consequences" (6,557) and "Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization" (4,836).
Showing 50 of 98 papers. Every paper with more than 1,126 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay Iris F. F. Benzie, JJ Strain · Analytical Biochemistry | Jul 1996 | 23,032 |
| 2 | Maternal and child undernutrition: global and regional exposures and health consequences Robert E. Black, Lindsay Helen Allen, Zulfiqar Ahmed Bhutta et al. · The Lancet | 2008 | 6,557 |
| 3 | Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science | 28 Oct 2004 | 4,836 |
| 4 | Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients Francesco Locatelli, Steven N. Fishbane, Geoffrey A. Block et al. · American Journal of Nephrology | 2017 | 4,818 |
| 5 | Anemia of Chronic Disease Günter Weiß, Lawrence T. Goodnough · New England Journal of Medicine | 9 Mar 2005 | 3,793 |
| 6 | A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis John N. Feder et al. · Nature Genetics | Aug 1996 | 3,727 |
| 7 | Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death Orah S. Platt, Donald J. Brambilla, Wendell F. Rosse et al. · New England Journal of Medicine | 9 Jun 1994 | 3,370 |
| 8 | Cloning and characterization of a mammalian proton-coupled metal-ion transporter Hiromi Gunshin, Bryan Mackenzie, Urs V. Berger et al. · Nature | 31 Jul 1997 | 3,203 |
| 9 | Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005 Erin McLean, Mary E. Cogswell, Ines M. Egli et al. · Public Health Nutrition | 23 May 2008 | 2,766 |
| 10 | Bacterial iron homeostasis Simon Colin Andrews, Andrea K. Robinson, Francisco Rodríguez‐Quiñones · FEMS Microbiology Reviews | 12 May 2003 | 2,754 |
| 11 | The ferritins: molecular properties, iron storage function and cellular regulation Pauline M. Harrison, Paolo Arosio · Biochimica et Biophysica Acta (BBA) - Bioenergetics | Jul 1996 | 2,698 |
| 12 | The role of iron and reactive oxygen species in cell death Scott J. Dixon, Brent R. Stockwell · Nature Chemical Biology | 17 Dec 2013 | 2,410 |
| 13 | Sickle-cell disease David C. Rees, Thomas Neil Williams, Mark T. Gladwin · The Lancet | Dec 2010 | 2,398 |
| 14 | What works? Interventions for maternal and child undernutrition and survival Zulfiqar Ahmed Bhutta, Tahmeed Ahmed, Robert E. Black et al. · The Lancet | Feb 2008 | 2,307 |
| 15 | IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin Elizabeta Nemeth, Seth Rivera, Victoria R. Gabayan et al. · Journal of Clinical Investigation | May 2004 | 2,242 |
| 16 | Plasminogen: Purification from Human Plasma by Affinity Chromatography Dale G. Deutsch, Edwin T. Mertz · Science | 4 Dec 1970 | 2,146 |
| 17 | Two to Tango: Regulation of Mammalian Iron Metabolism Matthias W. Hentze, Martina Ulrike Muckenthaler, Bruno Galy et al. · Cell | Jul 2010 | 2,142 |
| 18 | Disorders of Iron Metabolism Nancy C. Andrews · New England Journal of Medicine | 23 Dec 1999 | 2,127 |
| 19 | A systematic analysis of global anemia burden from 1990 to 2010 Nicholas J Kassebaum, Rashmi Jasrasaria, Mohsen Naghavi et al. · Blood | 2 Dec 2013 | 2,124 |
| 20 | Normalization of Hemoglobin Level in Patients with Chronic Kidney Disease and Anemia Tilman Bernhard Drüeke, Francesco Locatelli, Naomi Clyne et al. · New England Journal of Medicine | 15 Nov 2006 | 2,113 |
| 21 | Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency Stefan D. Anker, Josep Comín Colet, Gerasimos S Filippatos et al. · New England Journal of Medicine | 17 Nov 2009 | 2,090 |
| 22 | Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy Joseph Douglas Mancias, Xiaoxu Wang, Steven P. Gygi et al. · Nature | 28 Mar 2014 | 2,088 |
| 23 | The Epidemiology of Global Micronutrient Deficiencies Regan Lucas Bailey, Keith P. West, Robert E. Black · Annals of Nutrition and Metabolism | 2015 | 2,053 |
| 24 | Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data Gretchen A Stevens, Mariel McKenzie Finucane, Luz Maria De‐Regil et al. · The Lancet Global Health | 25 Jun 2013 | 1,983 |
| 25 | CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia Haydar Frangoul et al. · New England Journal of Medicine | 5 Dec 2020 | 1,969 |
| 26 | Global epidemiology of haemoglobin disorders and derived service indicators Bernadette Modell · Bulletin of the World Health Organization | Jun 2008 | 1,934 |
| 27 | Ferroptosis is an autophagic cell death process Minghui Gao, Prashant Monian, Qiuhui Pan et al. · Cell Research | 12 Aug 2016 | 1,906 |
| 28 | Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron Trude Helen Flo, Kelly D. Smith, Shintaro Sato et al. · Nature | 7 Nov 2004 | 1,904 |
| 29 | The role of iron in brain ageing and neurodegenerative disorders Roberta J. Ward, Fabio Andrea Zucca, Jeff H. Duyn et al. · The Lancet Neurology | 15 Sep 2014 | 1,864 |
| 30 | Zinc coordination, function, and structure of zinc enzymes and other proteins Bert L. Vallée, David S. Auld · Biochemistry | 19 Jun 1990 | 1,790 |
| 31 | Balancing Acts Matthias W. Hentze, Martina Ulrike Muckenthaler, Nancy C. Andrews · Cell | Apr 2004 | 1,736 |
| 32 | Cerebrovascular accidents in sickle cell disease: rates and risk factors. Kwaku Ohene‐Frempong, Steven J. Weiner, Lynn A. Sleeper et al. · PubMed | 1998 | 1,718 |
| 33 | A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload Christelle Pigeon, Gennady P. Ilyin, Brice Courselaud et al. · Journal of Biological Chemistry | Mar 2001 | 1,711 |
| 34 | Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload Lisa Anderson · European Heart Journal | Dec 2001 | 1,687 |
| 35 | Iron and cancer: more ore to be mined Suzy V. Torti, Frank M. Torti · Nature reviews. Cancer | 18 Apr 2013 | 1,674 |
| 36 | Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter Adriana Donovan, Alison Brownlie, Yi Zhou et al. · Nature | Feb 2000 | 1,673 |
| 37 | Iron-Deficiency Anemia Clara Camaschella · New England Journal of Medicine | 6 May 2015 | 1,658 |
| 38 | Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation Tomas Ganz · Blood | 31 Mar 2003 | 1,561 |
| 39 | Iron deficiency anaemia Anthony C. Lopez, P. Cacoub, Iain C. Macdougall et al. · The Lancet | 25 Aug 2015 | 1,506 |
| 40 | Abnormal human haemoglobins J. B. Clegg, Michael A. Naughton, David John Weatherall · Journal of Molecular Biology | Aug 1966 | 1,496 |
| 41 | Review on iron and its importance for human health. Nazanin Abbaspour, Richard Hurrell, Roya Kelishadi · PubMed | Feb 2014 | 1,492 |
| 42 | Beta-thalassemia Renzo Galanello, Raffaella Origa · Orphanet Journal of Rare Diseases | 21 May 2010 | 1,490 |
| 43 | Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia Jack M. Guralnik, Richard S. Eisenstaedt, Luigi Ferrucci et al. · Blood | 6 Jul 2004 | 1,469 |
| 44 | Recent advances in iron oxide nanocrystal technology for medical imaging☆ Claire Corot, Paz S. Robert, JM Idée et al. · Advanced Drug Delivery Reviews | 2 Oct 2006 | 1,467 |
| 45 | Copper biochemistry and molecular biology Maria Christine Linder, Maryam Hazegh-Azam · American Journal of Clinical Nutrition | May 1996 | 1,438 |
| 46 | The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation Gaël Nicolas, Caroline Chauvet, Lydie Viatte et al. · Journal of Clinical Investigation | Oct 2002 | 1,434 |
| 47 | A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation Andrew Tristan McKie, Paola Marciani, Andreas Rolfs et al. · Molecular Cell | Feb 2000 | 1,430 |
| 48 | Sickle cell disease Gregory James Kato, Frédéric B. Piel, Clarice D. Reid et al. · Nature Reviews Disease Primers | 14 Mar 2018 | 1,422 |
| 49 | Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein Elizabeta Nemeth, Erika V. Valore, Mary Territo et al. · Blood | 17 Mar 2003 | 1,418 |
| 50 | Nutritional iron deficiency Michael Bruce Zimmermann, Richard F. Hurrell · The Lancet | Aug 2007 | 1,416 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.