Topic · Lipid metabolism and disorders
Most cited papers in Lipid metabolism and disorders
What are the most cited papers in Lipid metabolism and disorders?
The most cited paper in Lipid metabolism and disorders is "Diagnosis and Management of the Metabolic Syndrome" (Scott M. Grundy, James I. Cleeman, Stephen R. Daniels et al., 2005), with 11,924 citations. Next come "Design and validation of a histological scoring system for nonalcoholic fatty liver disease†" (10,904) and "The gut microbiota as an environmental factor that regulates fat storage" (6,319).
Showing 50 of 99 papers. Every paper with more than 764 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Diagnosis and Management of the Metabolic Syndrome Scott M. Grundy, James I. Cleeman, Stephen R. Daniels et al. · Circulation | 13 Sep 2005 | 11,924 |
| 2 | Design and validation of a histological scoring system for nonalcoholic fatty liver disease† David Erwin Kleiner, Elizabeth M. Brunt, Mark L. Van Natta et al. · Hepatology | 24 May 2005 | 10,904 |
| 3 | The gut microbiota as an environmental factor that regulates fat storage Fredrik Bäckhed, Hao Ding, Ting Wang et al. · Proceedings of the National Academy of Sciences | 25 Oct 2004 | 6,319 |
| 4 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt et al. · PLoS Genetics | 15 May 2014 | 4,798 |
| 5 | Abdominal obesity and metabolic syndrome Jean‐Pierre Després, Isabelle Lemieux · Nature | 13 Dec 2006 | 4,402 |
| 6 | Inflammatory Mechanisms in Obesity Margaret F. Gregor, Gökhan S. Hotamışlıgil · Annual Review of Immunology | Mar 2011 | 3,743 |
| 7 | Biological, clinical and population relevance of 95 loci for blood lipids Tanya M. Teslovich et al. · Nature | Aug 2010 | 3,706 |
| 8 | Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease Stefano Romeo, Julia Kozlitina, Chao Xing et al. · Nature Genetics | 25 Sep 2008 | 3,462 |
| 9 | Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia Christian Weyer, Tohru Funahashi, Sachiyo Tanaka et al. · The Journal of Clinical Endocrinology & Metabolism | May 2001 | 3,449 |
| 10 | The changing landscape of atherosclerosis Peter Libby · Nature | 21 Apr 2021 | 2,879 |
| 11 | Endothelial Function and Dysfunction John Eric Deanfield, Julian Halcox, Ton J. Rabelink · Circulation | 13 Mar 2007 | 2,669 |
| 12 | C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction John S Yudkin, Coen D.A. Stehouwer, JEF J. EMEIS et al. · Arteriosclerosis Thrombosis and Vascular Biology | Apr 1999 | 2,475 |
| 13 | Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine Lora V. Hooper, Melissa Hirose Wong, Anders G Thelin et al. · Science | 2 Feb 2001 | 2,232 |
| 14 | Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications Elisa Fabbrini, Shelby A. Sullivan, Samuel Klein · Hepatology | 9 Sep 2009 | 2,135 |
| 15 | Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning Samuel H. Davis, Thomas H. Aldrich, Pamela F. Jones et al. · Cell | Dec 1996 | 1,998 |
| 16 | Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders Donald S. Fredrickson, Robert I. Levy, Robert S. Lees · New England Journal of Medicine | 5 Jan 1967 | 1,931 |
| 17 | Polycystic ovary syndrome Ricardo Azziz, Enrico Carmina, Zi‐Jiang Chen et al. · Nature Reviews Disease Primers | 11 Aug 2016 | 1,892 |
| 18 | Polycystic Ovary Syndrome David A. Ehrmann · New England Journal of Medicine | 23 Mar 2005 | 1,891 |
| 19 | Age-specific Incidence Rates of Myocardial Infarction and Angina in Women with Systemic Lupus Erythematosus: Comparison with the Framingham Study S Manzi, Elaine N. Meilahn, Joan E. Rairie et al. · American Journal of Epidemiology | Mar 1997 | 1,844 |
| 20 | Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression Eek Joong Park, Jun Hee Lee, Guann‐Yi Yu et al. · Cell | 2010 | 1,794 |
| 21 | Dyslipidemia in Obesity: Mechanisms and Potential Targets Boudewijn Klop, J ELTE, Manuel Castro Cabezas · Nutrients | 12 Apr 2013 | 1,693 |
| 22 | H OW H OST -M ICROBIAL I NTERACTIONS S HAPE THE N UTRIENT E NVIRONMENT OF THE M AMMALIAN I NTESTINE Lora V. Hooper, Tore Midtvedt, Jeffrey I. Gordon · Annual Review of Nutrition | Jul 2002 | 1,633 |
| 23 | Newly identified loci that influence lipid concentrations and risk of coronary artery disease Cristen J. Willer et al. · Nature Genetics | 13 Jan 2008 | 1,609 |
| 24 | Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice Marek Dráb, Paul Verkade, Marlies Elger et al. · Science | 28 Sep 2001 | 1,564 |
| 25 | Nutritional Regulation of the Insulin-Like Growth Factors* Jean‐Paul Thissen, Jean‐Marie Ketelslegers, Louis E. Underwood · Endocrine Reviews | Feb 1994 | 1,552 |
| 26 | Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women1 Richard S. Legro, Allen R. Kunselman, William C. Dodson et al. · The Journal of Clinical Endocrinology & Metabolism | 1999 | 1,539 |
| 27 | Inflammatory Cytokines and the Risk to Develop Type 2 Diabetes Joachim Spranger, Anja Kroke, Matthias Möhlig et al. · Diabetes | Mar 2003 | 1,505 |
| 28 | Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease David Højland Ipsen, Jens Lykkesfeldt, Pernille Tveden‐Nyborg · Cellular and Molecular Life Sciences | 23 Jun 2018 | 1,504 |
| 29 | Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States Michael K. Badman, Pavlos Pissios, Adam Richard Kennedy et al. · Cell Metabolism | Jun 2007 | 1,501 |
| 30 | Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system Hellmut G. Augustin, Gou Young Koh, Gavin Thurston et al. · Nature Reviews Molecular Cell Biology | 23 Feb 2009 | 1,468 |
| 31 | Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA Joseph L. Goldstein, Helmut G. Schrott, William R. Hazzard et al. · Journal of Clinical Investigation | Jul 1973 | 1,459 |
| 32 | Metabolic Syndrome: Updates on Pathophysiology and Management in 2021 Gracia Fahed, Laurence Aoun, Morgan Bou Zerdan et al. · International Journal of Molecular Sciences | 12 Jan 2022 | 1,438 |
| 33 | Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk. M A Austin, Mary‐Claire King, K M Vranizan et al. · Circulation | Aug 1990 | 1,424 |
| 34 | Premature mortality due to cardiovascular disease in hypopituitarism T. Rosén, B.‐Å. Bengtsson · The Lancet | Aug 1990 | 1,418 |
| 35 | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans Sekar Kathiresan et al. · Nature Genetics | 13 Jan 2008 | 1,411 |
| 36 | Subendothelial Lipoprotein Retention as the Initiating Process in Atherosclerosis Ira A. Tabas, Kevin Jon Williams, Jan Borén · Circulation | 15 Oct 2007 | 1,406 |
| 37 | Common variants at 30 loci contribute to polygenic dyslipidemia Sekar Kathiresan et al. · Nature Genetics | 7 Dec 2008 | 1,383 |
| 38 | Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis Anna Mae Diehl, Christopher Paul Day · New England Journal of Medicine | 22 Nov 2017 | 1,327 |
| 39 | The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. Philip A. Kern, Mehrnoosh Saghizadeh, Juling Ong et al. · Journal of Clinical Investigation | May 1995 | 1,312 |
| 40 | Angiopoietin-1 protects the adult vasculature against plasma leakage Gavin Thurston, John S. Rudge, Ella Ioffe et al. · Nature Medicine | Apr 2000 | 1,310 |
| 41 | Role of cholesterol and lipid organization in disease Frederick R. Maxfield, Ira A. Tabas · Nature | 30 Nov 2005 | 1,304 |
| 42 | Metabolic Syndrome Paresh Dandona, Ahmad Aljada, Ajay Chaudhuri et al. · Circulation | 22 Mar 2005 | 1,272 |
| 43 | Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. David A. Ehrmann, Randall B. Barnes, Robert L. Rosenfield et al. · Diabetes Care | 1999 | 1,265 |
| 44 | Adiponectin and Metabolic Syndrome Yūji Matsuzawa, Tohru Funahashi, Shinji Kihara et al. · Arteriosclerosis Thrombosis and Vascular Biology | 14 Oct 2003 | 1,209 |
| 45 | PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene. Kristina Schoonjans, Julia Peinado‐Onsurbe, Anne‐Marie Lefebvre et al. · The EMBO Journal | Oct 1996 | 1,183 |
| 46 | The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice Aimin Xu, Yu Wang, Hussila Keshaw et al. · Journal of Clinical Investigation | Jul 2003 | 1,168 |
| 47 | Lipid rafts: bringing order to chaos LINDA JOY PIKE · Journal of Lipid Research | 31 Mar 2003 | 1,147 |
| 48 | Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Josef R. Patsch, Gero Miesenböck, Thomas Hopferwieser et al. · Arteriosclerosis and Thrombosis A Journal of Vascular Biology | Nov 1992 | 1,136 |
| 49 | Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease Gerald I. Shulman · New England Journal of Medicine | 17 Sep 2014 | 1,125 |
| 50 | Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis Lisa Moran, Marie L Misso, Robert A. Wild et al. · Human Reproduction Update | 2010 | 1,116 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.