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Topic · Cardiology and Cardiovascular Medicine

Lipid metabolism and disorders

Lipid metabolism and disorders is a research topic within Cardiology and Cardiovascular Medicine. Science Explorer counts 20k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the genetic, pharmacologic, and physiological aspects of lipid metabolism, particularly the role of ANGPTL3, lipoprotein lipase, and related proteins in regulating triglyceride levels and their implications for cardiovascular diseases such as familial chylomicronemia syndrome and atherosclerosis. It also explores the involvement of adipose tissue and metabolic syndrome in lipid regulation.

  • ANGPTL3
  • Lipoprotein Lipase
  • Triglyceride Metabolism
  • Familial Chylomicronemia Syndrome
  • GPIHBP1
  • ANGPTL4
  • Adipose Tissue
  • Metabolic Syndrome
  • HDL Cholesterol
  • Atherosclerosis
Research works
20k
fractional, since 1950
In the world top 10%
2k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+6%
the tick is no change
Largest producer
China
49% of the 10 largest, 2022-now
Lipid metabolism and disorders

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Lipid metabolism and disorders research?

By volume, China and the United States publish the most (1.2k and 526 works in 2022-now).

By volume, 2022-now

  1. 1 China 1.2k works
  2. 2 United States 526 works
  3. 3 India 123 works
  4. 4 Japan 105 works
  5. 5 Italy 89 works
  6. 6 Canada 76 works
  7. 7 United Kingdom 73 works
  8. 8 Germany 63 works
  9. 9 Türkiye 63 works
  10. 10 Russia 62 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 49.4%United States: 22.6%India: 5.3%Japan: 4.5%6 others listed: 18.3%49%largest
China1,150 · 49.4%United States526 · 22.6%India123 · 5.3%Japan105 · 4.5%6 others listed425 · 18.3%

Shares of the rows listed above, not of the whole node.

Which institutions lead Lipid metabolism and disorders research?

By volume in 2022-now, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Lipid metabolism and disorders research, followed by Capital Medical University and Shanghai Jiao Tong University.

By volume, 2022-now

  1. 1 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 30 works
  2. 2 Capital Medical UniversityChina 26 works
  3. 3 Shanghai Jiao Tong UniversityChina 25 works
  4. 4 Nanjing Medical UniversityChina 24 works
  5. 5 Harvard UniversityUnited States 24 works
  6. 6 Zhejiang UniversityChina 19 works
  7. 7 Sun Yat-sen UniversityChina 18 works
  8. 8 Central South UniversityChina 18 works
  9. 9 Beijing University of Chinese MedicineChina 18 works
  10. 10 Peking UniversityChina 17 works

Who are the leading researchers in Lipid metabolism and disorders?

The most-cited researchers publishing on Lipid metabolism and disorders include George Davey Smith, Walter Churchill Willett and Mark J. Daly.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Walter Churchill Willett United States 411k citations
  3. 3 Mark J. Daly United States 403k citations
  4. 4 Stacey L. Gabriel United States 402k citations
  5. 5 Guido Kroemer France 386k citations
  6. 6 Jost Bruno Jonas Germany 350k citations
  7. 7 Hermann Brenner Germany 343k citations
  8. 8 Jun Wang China 340k citations
  9. 9 Mika Kivimäki United Kingdom 318k citations
  10. 10 Gregory Y.H. Lip United Kingdom 311k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Lipid metabolism and disorders?

The most cited paper in Lipid metabolism and disorders is "Diagnosis and Management of the Metabolic Syndrome" (Scott M. Grundy, James I. Cleeman, Stephen R. Daniels et al., 2005), with 11,924 citations. Next come "Design and validation of a histological scoring system for nonalcoholic fatty liver disease†" (10,904) and "The gut microbiota as an environmental factor that regulates fat storage" (6,319).

Most cited papers
#PaperReleasedCitations
1 Diagnosis and Management of the Metabolic Syndrome Scott M. Grundy, James I. Cleeman, Stephen R. Daniels et al. · Circulation Open access 13 Sep 2005 11,924
2 Design and validation of a histological scoring system for nonalcoholic fatty liver disease† David Erwin Kleiner, Elizabeth M. Brunt, Mark L. Van Natta et al. · Hepatology 24 May 2005 10,904
3 The gut microbiota as an environmental factor that regulates fat storage Fredrik Bäckhed, Hao Ding, Ting Wang et al. · Proceedings of the National Academy of Sciences Open access 25 Oct 2004 6,319
4 Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt et al. · PLoS Genetics Open access 15 May 2014 4,798
5 Abdominal obesity and metabolic syndrome Jean‐Pierre Després, Isabelle Lemieux · Nature 13 Dec 2006 4,402
All 99 most cited papers, with filters and sorting

Where is Lipid metabolism and disorders research done?

The largest centres of Lipid metabolism and disorders research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China).

Largest cities, 2022-now

  1. 1 BeijingChina 152 works
  2. 2 ShanghaiChina 92 works
  3. 3 GuangzhouChina 66 works
  4. 4 NanjingChina 53 works
  5. 5 HangzhouChina 44 works
  6. 6 WuhanChina 37 works
  7. 7 JinanChina 36 works
  8. 8 ChengduChina 36 works
  9. 9 ChangshaChina 34 works
  10. 10 New YorkUnited States 29 works
See Lipid metabolism and disorders on the map

Where is the best place to study Lipid metabolism and disorders?

Among universities, judged by research, Harvard University, Chinese Academy of Medical Sciences & Peking Union Medical College and Western University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 15.83%fractional works in this field (log) →share of work in the world top 10% →Western UniversityHarvard UniversityChinese Academy of M…Nanjing Medical Univ…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 81.119.9%2.8×24 +8.0%
2Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 72.316.5%10.5×30 +29.2%
3Western UniversityCanada 68.920.8%9.0×14 -14.1%
4Nanjing Medical UniversityChina 62.513.6%9.9×24 +17.2%
5Zhejiang UniversityChina 55.214.9%2.7×19 +43.4%
6Shanghai University of Traditional Chinese MedicineChina 55.214.5%23.3×17 +90.6%
7Capital Medical UniversityChina 55.17.6%9.1×26 +10.4%
8Beijing University of Chinese MedicineChina 53.414.5%27.4×18 +29.4%
9Chengdu University of Traditional Chinese MedicineChina 53.419.2%16.2×11 +78.9%
10Southern Medical UniversityChina 50.716.8%8.0×13 +35.8%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Lipid metabolism and disorders, country by country

Is Lipid metabolism and disorders research growing?

Output in 2022-2025 was 6% higher than in 2018-2021, peaking in 2013. The fastest-growing topics are Lipid metabolism and disorders.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Lipid metabolism and disorders as a percentage of every work published that year, 0.013% in 2024.

still counting0.010%0.020%0.030%Lipid metabolism and disorders0.013% in 202519801990200020102020

Fractional works of Lipid metabolism and disorders over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Lipid metabolism and disorders10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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