Topic · Lymphatic System and Diseases
Most cited papers in Lymphatic System and Diseases
What are the most cited papers in Lymphatic System and Diseases?
The most cited paper in Lymphatic System and Diseases is "Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma" (Noel Weidner, Joseph P. Semple, William R. W. Welch et al., 1991), with 5,701 citations. Next come "Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia" (3,449) and "VEGF receptor signalling ? in control of vascular function" (3,138).
Showing 50 of 100 papers. Every paper with more than 744 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma Noel Weidner, Joseph P. Semple, William R. W. Welch et al. · New England Journal of Medicine | 3 Jan 1991 | 5,701 |
| 2 | Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia Christian Weyer, Tohru Funahashi, Sachiyo Tanaka et al. · The Journal of Clinical Endocrinology & Metabolism | May 2001 | 3,449 |
| 3 | VEGF receptor signalling ? in control of vascular function Anna‐Karin Olsson, Anna Dimberg, Johan Kreuger et al. · Nature Reviews Molecular Cell Biology | 21 Apr 2006 | 3,138 |
| 4 | Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis Chitra Suri, Pamela F. Jones, Sybill Patan et al. · Cell | Dec 1996 | 2,867 |
| 5 | American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors Kathryn H. Schmitz, Kerry S. Courneya, Charles Edwards Matthews et al. · Medicine & Science in Sports & Exercise | 11 Jun 2010 | 2,821 |
| 6 | VEGF in Signaling and Disease: Beyond Discovery and Development Rajendra S. Apte, Daniel S. Chen, Napoleone Ferrara · Cell | Mar 2019 | 2,788 |
| 7 | Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises Annika Armulik, Guillem Genové, Christer Betsholtz · Developmental Cell | Aug 2011 | 2,724 |
| 8 | Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature | Jul 1995 | 2,634 |
| 9 | Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor Shay Söker, Seiji Takashima, Hua Miao et al. · Cell | Mar 1998 | 2,486 |
| 10 | Endothelial Progenitor Cells Carmen Urbich, Stefanie Dimmeler · Circulation Research | 19 Aug 2004 | 2,373 |
| 11 | High interstitial fluid pressure — an obstacle in cancer therapy Carl‐Henrik Heldin, Kristofer Rubin, Kristian Pietras et al. · Nature reviews. Cancer | Oct 2004 | 2,216 |
| 12 | Molecular regulation of angiogenesis and lymphangiogenesis Ralf H. Adams, Kari K. Alitalo · Nature Reviews Molecular Cell Biology | 24 May 2007 | 2,040 |
| 13 | Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo1 Vidya Mohamed‐Ali, S Goodrick, Ataullah Rawesh et al. · The Journal of Clinical Endocrinology & Metabolism | Dec 1997 | 1,967 |
| 14 | Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell | Jul 2004 | 1,960 |
| 15 | Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis Tracey DiSipio, Sheree Rye, Beth M Newman et al. · The Lancet Oncology | 26 Mar 2013 | 1,900 |
| 16 | Vascular Endothelial Growth Factor and Angiogenesis Ann Hoeben, Bart Landuyt, Martin Highley et al. · Pharmacological Reviews | Dec 2004 | 1,852 |
| 17 | Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma Noel Weidner, Judah Folkman, Franco Dalla Pozza et al. · JNCI Journal of the National Cancer Institute | 16 Dec 1992 | 1,800 |
| 18 | Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis Mihaela Skobe, Thomas Hawighorst, David G. Jackson et al. · Nature Medicine | Feb 2001 | 1,760 |
| 19 | Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial Brian P O'Sullivan, Aileen M. Davis, ROBERT E. TURCOTTE et al. · The Lancet | Jun 2002 | 1,613 |
| 20 | Enhanced cellular proliferation in intact stenotic lesions derived from human arteriovenous fistulas and peripheral bypass grafts. Does it correlate with flow parameters? L Hofstra, J H Tordoir, P J Kitslaar et al. · PubMed | 15 Sep 1996 | 1,607 |
| 21 | The role of pericytes in blood-vessel formation and maintenance Gabriele Bergers, Steven Song · Neuro-Oncology | Oct 2005 | 1,601 |
| 22 | Prox1 Function Is Required for the Development of the Murine Lymphatic System Jeffrey T. Wigle, Guillermo C. Oliver · Cell | Sep 1999 | 1,599 |
| 23 | Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy Harold F. Dvorak · Journal of Clinical Oncology | 30 Oct 2002 | 1,586 |
| 24 | Lymphangiogenesis: Molecular Mechanisms and Future Promise Tuomas Tammela, Kari K. Alitalo · Cell | Feb 2010 | 1,469 |
| 25 | Human Endothelial Progenitor Cells From Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation Into Vascular Structures Oren M. Tepper, Robert D. Galiano, Jennifer M. Capla et al. · Circulation | 25 Nov 2002 | 1,461 |
| 26 | Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Arja Kaipainen, Jaana E. Korhonen, Tuija Mustonen et al. · Proceedings of the National Academy of Sciences | 11 Apr 1995 | 1,452 |
| 27 | Angiogenesis in cancer Naoyo Nishida, Hirohisa Yano, Takashi Nishida et al. · Vascular Health and Risk Management | Aug 2006 | 1,449 |
| 28 | The systemic inflammation-based Glasgow Prognostic Score: A decade of experience in patients with cancer Donald C. McMillan · Cancer Treatment Reviews | 17 Sep 2012 | 1,438 |
| 29 | Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins Marika J. Karkkainen, Paula Haiko, Kirsi Sainio et al. · Nature Immunology | 23 Nov 2003 | 1,435 |
| 30 | A Pooled Analysis of Bone Marrow Micrometastasis in Breast Cancer Stephan Braun et al. · New England Journal of Medicine | 24 Aug 2005 | 1,397 |
| 31 | Leakage-Resistant Blood Vessels in Mice Transgenically Overexpressing Angiopoietin-1 Gavin Thurston, Chitra Suri, Kenneth J. Smith et al. · Science | 24 Dec 1999 | 1,369 |
| 32 | Angiopoietin-1 protects the adult vasculature against plasma leakage Gavin Thurston, John S. Rudge, Ella Ioffe et al. · Nature Medicine | Apr 2000 | 1,310 |
| 33 | Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice Michael Jeltsch, Arja Kaipainen, Vladimir Joukov et al. · Science | 30 May 1997 | 1,297 |
| 34 | Lymphatic Mapping and Sentinel Node Biopsy in the Patient With Breast Cancer John J. Albertini · JAMA | 11 Dec 1996 | 1,291 |
| 35 | Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases Vera Eremina, Manish M. Sood, Jody J. Haigh et al. · Journal of Clinical Investigation | Mar 2003 | 1,290 |
| 36 | Lymphangiogenesis in development and human disease Kari K. Alitalo, Tuomas Tammela, Tatiana V. Petrova · Nature | 14 Dec 2005 | 1,283 |
| 37 | VEGF-D promotes the metastatic spread of tumor cells via the lymphatics Steven A. Stacker, Carol Caesar, Megan E. Baldwin et al. · Nature Medicine | Feb 2001 | 1,254 |
| 38 | Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4) Marc G. Achen, Michael Jeltsch, Eola Kukk et al. · Proceedings of the National Academy of Sciences | 20 Jan 1998 | 1,215 |
| 39 | Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors Ricky T. Tong, Yves Boucher, Sergey V. Kozin et al. · Cancer Research | Jun 2004 | 1,195 |
| 40 | Effects of Aerobic and Resistance Exercise in Breast Cancer Patients Receiving Adjuvant Chemotherapy: A Multicenter Randomized Controlled Trial Kerry S. Courneya, ROANNE J. SEGAL, John Robert Mackey et al. · Journal of Clinical Oncology | 5 Sep 2007 | 1,189 |
| 41 | Microvascular fluid exchange and the revised Starling principle J. Rodney Levick, C. C. Michel · Cardiovascular Research | 3 Mar 2010 | 1,177 |
| 42 | The perivascular niche regulates breast tumour dormancy Cyrus Michael Ghajar, Héctor Peinado, Hidetoshi Mori et al. · Nature Cell Biology | 2 Jun 2013 | 1,159 |
| 43 | Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization Jun‐ichi Yamaguchi, Kengo Fukushima Kusano, Osamu Masuo et al. · Circulation | 10 Mar 2003 | 1,150 |
| 44 | Dendritic-cell trafficking to lymph nodes through lymphatic vessels Gwendalyn J. Randolph, Véronique Angeli, Melody A. Swartz · Nature reviews. Immunology | Aug 2005 | 1,113 |
| 45 | Angiosarcomas Express Mixed Endothelial Phenotypes of Blood and Lymphatic Capillaries Silvana Breiteneder-Geleff, Afschin Soleiman, Heinrich Kowalski et al. · American Journal Of Pathology | Feb 1999 | 1,099 |
| 46 | Effects of exercise on breast cancer patients and survivors: a systematic review and meta-analysis Margaret L. McNeely · Canadian Medical Association Journal | 4 Jul 2006 | 1,096 |
| 47 | Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis Masabumi Shibuya, Lena Claesson‐Welsh · Experimental Cell Research | 6 Dec 2005 | 1,063 |
| 48 | Autocrine VEGF Signaling Is Required for Vascular Homeostasis Sunyoung Lee, Tom T. Chen, Chad L. Barber et al. · Cell | Aug 2007 | 1,055 |
| 49 | Integrins in angiogenesis and lymphangiogenesis Christie J. Avraamides, Barbara H. Garmy-Susini, Judith A. Varner · Nature reviews. Cancer | 22 May 2008 | 1,052 |
| 50 | VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment Claus Cursiefen, Lu Chen, Leonardo P. Borges et al. · Journal of Clinical Investigation | Apr 2004 | 1,033 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.