Science Explorer Back to mapMap
Discussion
Topic · Oncology

Lymphatic System and Diseases

Lymphatic System and Diseases is a research topic within Oncology. Science Explorer counts 17k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the molecular mechanisms, regulation, and role of lymphangiogenesis in cancer metastasis and disease, with a particular emphasis on the involvement of VEGF-C, tumor lymphatics, macrophages, podoplanin, and VEGFR-3 signaling. It also addresses the implications of lymphedema and inflammation in the context of lymphatic vascular development.

  • Lymphangiogenesis
  • VEGF-C
  • Metastasis
  • Lymphatic Endothelial Cells
  • Tumor Lymphatics
  • Macrophages
  • Podoplanin
  • Lymphedema
  • VEGFR-3 Signaling
  • Inflammation
Research works
17k
fractional, since 1950
In the world top 10%
1.7k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+15%
the tick is no change
Largest producer
United States
37% of the 10 largest, 2022-now
Lymphatic System and Diseases

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Lymphatic System and Diseases research?

By volume, the United States and China publish the most (1.1k and 550 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.1k works
  2. 2 China 550 works
  3. 3 Japan 253 works
  4. 4 United Kingdom 168 works
  5. 5 Germany 161 works
  6. 6 Brazil 159 works
  7. 7 India 152 works
  8. 8 Italy 146 works
  9. 9 Türkiye 132 works
  10. 10 South Korea 109 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 36.8%China: 19.0%Japan: 8.7%United Kingdom: 5.8%6 others listed: 29.7%37%largest
United States1,065 · 36.8%China550 · 19.0%Japan253 · 8.7%United Kingdom168 · 5.8%6 others listed859 · 29.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Lymphatic System and Diseases research?

By volume in 2022-now, Harvard University publishes the most Lymphatic System and Diseases research, followed by Memorial Sloan Kettering Cancer Center and Cleveland Clinic.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 63 works
  2. 2 Memorial Sloan Kettering Cancer CenterUnited States 47 works
  3. 3 Cleveland ClinicUnited States 25 works
  4. 4 Capital Medical UniversityChina 24 works
  5. 5 Mayo ClinicUnited States 22 works
  6. 6 Sun Yat-sen UniversityChina 22 works
  7. 7 The University of Texas MD Anderson Cancer CenterUnited States 20 works
  8. 8 Cornell UniversityUnited States 19 works
  9. 9 Creative CommonsUnited States 18 works
  10. 10 Vanderbilt UniversityUnited States 18 works

Who are the leading researchers in Lymphatic System and Diseases?

The most-cited researchers publishing on Lymphatic System and Diseases include Giuseppe Remuzzi, Gregory Y.H. Lip and Luigi Ferrucci.

  1. 1 Giuseppe Remuzzi Italy 328k citations
  2. 2 Gregory Y.H. Lip United Kingdom 311k citations
  3. 3 Luigi Ferrucci United States 281k citations
  4. 4 Hagop M. Kantarjian United States 273k citations
  5. 5 Patrick M. Bossuyt Netherlands 270k citations
  6. 6 Ralph B. D’Agostino United States 255k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Lymphatic System and Diseases?

The most cited paper in Lymphatic System and Diseases is "Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma" (Noel Weidner, Joseph P. Semple, William R. W. Welch et al., 1991), with 5,701 citations. Next come "Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia" (3,449) and "VEGF receptor signalling ? in control of vascular function" (3,138).

Most cited papers
#PaperReleasedCitations
1 Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma Noel Weidner, Joseph P. Semple, William R. W. Welch et al. · New England Journal of Medicine 3 Jan 1991 5,701
2 Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia Christian Weyer, Tohru Funahashi, Sachiyo Tanaka et al. · The Journal of Clinical Endocrinology & Metabolism May 2001 3,449
3 VEGF receptor signalling ? in control of vascular function Anna‐Karin Olsson, Anna Dimberg, Johan Kreuger et al. · Nature Reviews Molecular Cell Biology Review 21 Apr 2006 3,138
4 Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis Chitra Suri, Pamela F. Jones, Sybill Patan et al. · Cell Open access Dec 1996 2,867
5 American College of Sports Medicine Roundtable on Exercise Guidelines for Cancer Survivors Kathryn H. Schmitz, Kerry S. Courneya, Charles Edwards Matthews et al. · Medicine & Science in Sports & Exercise Open access 11 Jun 2010 2,821
All 100 most cited papers, with filters and sorting

Where is Lymphatic System and Diseases research done?

The largest centres of Lymphatic System and Diseases research in 2022-now are New York (United States), Beijing (China), Tokyo (Japan) and Boston (United States). Among places with at least 20 works in it, it is an unusually large share of all research in Cleveland.

Largest cities, 2022-now

  1. 1 New YorkUnited States 90 works
  2. 2 BeijingChina 86 works
  3. 3 TokyoJapan 63 works
  4. 4 BostonUnited States 58 works
  5. 5 ShanghaiChina 56 works
  6. 6 SeoulSouth Korea 55 works
  7. 7 LondonUnited Kingdom 51 works
  8. 8 São PauloBrazil 45 works
  9. 9 GuangzhouChina 41 works
  10. 10 HoustonUnited States 38 works

Where it is the local speciality

  1. ClevelandUS · 31.8 works5.6×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Lymphatic System and Diseases than the world average.

See Lymphatic System and Diseases on the map

Where is the best place to study Lymphatic System and Diseases?

Among universities, judged by research, Harvard University, Cornell University and Uppsala University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 20.22%fractional works in this field (log) →share of work in the world top 10% →Cornell UniversityUniversity of ZurichUppsala UniversityHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 76.310.3%5.6×63 +6.7%
2Cornell UniversityUnited States 73.425.3%4.0×19 +45.8%
3Uppsala UniversitySweden 62.818.0%4.6×9 +34.0%
4University of ZurichSwitzerland 60.420.0%5.3×13 +72.3%
5Peking UniversityChina 60.323.3%2.1×15 +50.9%
6Wroclaw Medical UniversityPoland 60.132.9%16.7×8 +17.4%
7University of CopenhagenDenmark 59.922.1%3.5×12 +41.2%
8University of South FloridaUnited States 57.015.1%7.7×12 +93.6%
9Vanderbilt UniversityUnited States 55.713.3%7.0×18 +55.9%
10New York UniversityUnited States 53.121.9%2.1×9 +62.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Lymphatic System and Diseases, country by country

Is Lymphatic System and Diseases research growing?

Output in 2022-2025 was 15% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Lymphatic System and Diseases.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Lymphatic System and Diseases as a percentage of every work published that year, 0.015% in 2024.

still counting0.010%0.020%Lymphatic System and Diseases0.018% in 202519801990200020102020

Fractional works of Lymphatic System and Diseases over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Lymphatic System and Diseases10.1% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

Ask a question or share a note about Lymphatic System and Diseases. Posts are plain text and can be reported.