Most cited papers in Lysosomal Storage Disorders Research
What are the most cited papers in Lysosomal Storage Disorders Research?
The most cited paper in Lysosomal Storage Disorders Research is "Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease" (Valentina Cappello, Laura Marchetti, Paola Parlanti et al., 2016), with 13,289 citations. Next come "Parkinson's disease" (3,905) and "Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice" (3,905).
Showing 50 of 100 papers. Every paper with more than 791 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease Valentina Cappello, Laura Marchetti, Paola Parlanti et al. · Scientific Reports | 11 Nov 2016 | 13,289 |
| 2 | Parkinson's disease Bastiaan R. Bloem, Michael S. Okun, Christine Klein · The Lancet | 11 Apr 2021 | 3,905 |
| 3 | Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Taichi Hara, Kenji D. Nakamura, Makoto Matsui et al. · Nature | 19 Apr 2006 | 3,905 |
| 4 | TFEB Links Autophagy to Lysosomal Biogenesis Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito et al. · Science | 26 May 2011 | 3,389 |
| 5 | Mechanisms of mitophagy Richard J. Youle, Derek P. Narendra · Nature Reviews Molecular Cell Biology | 22 Dec 2010 | 3,286 |
| 6 | How to Interpret LC3 Immunoblotting Noboru Mizushima, Tamotsu Yoshimori · Autophagy | 26 Nov 2007 | 2,643 |
| 7 | Prevalence of Lysosomal Storage Disorders Peter J. Meikle · JAMA | 20 Jan 1999 | 2,215 |
| 8 | Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion Mario Mauthe, Idil Orhon, Cecilia Rocchi et al. · Autophagy | 26 Jun 2018 | 2,198 |
| 9 | Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease E. Sidransky et al. · New England Journal of Medicine | 21 Oct 2009 | 2,179 |
| 10 | A Drosophila model of Parkinson's disease Mel Β. Feany, Welcome W. Bender · Nature | Mar 2000 | 2,156 |
| 11 | Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands Michael John Berridge, C. Peter Downes, Michael R. Hanley · Biochemical Journal | 15 Sep 1982 | 2,148 |
| 12 | Glycosyltransferases: Structures, Functions, and Mechanisms Luke L. Lairson, Bernard Henrissat, G.J. Davies et al. · Annual Review of Biochemistry | 9 Feb 2007 | 2,119 |
| 13 | The role of autophagy in neurodegenerative disease Ralph A. Nixon · Nature Medicine | Aug 2013 | 2,094 |
| 14 | Non-motor features of Parkinson disease Anthony H.V. Schapira, К. Ray Chaudhuri, Peter G. Jenner · Nature reviews. Neuroscience | 8 Jun 2017 | 2,084 |
| 15 | PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology | 19 Apr 2010 | 1,986 |
| 16 | Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides Michael John Berridge, REX M. C. DAWSON, C. Peter Downes et al. · Biochemical Journal | 15 May 1983 | 1,968 |
| 17 | Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum Elizabeth Axe, Simon A. Walker, Maria Manifava et al. · The Journal of Cell Biology | 25 Aug 2008 | 1,876 |
| 18 | CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis Julian David Gillmore et al. · New England Journal of Medicine | 26 Jun 2021 | 1,751 |
| 19 | Müller cells in the healthy and diseased retina Andreas Bringmann, Thomas Pannicke, Jens Grosche et al. · Progress in Retinal and Eye Research | Jul 2006 | 1,748 |
| 20 | Regulation of Mammalian Autophagy in Physiology and Pathophysiology Brinda Ravikumar, Sovan Sarkar, J. Eric Davies et al. · Physiological Reviews | Oct 2010 | 1,746 |
| 21 | Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin Jeehye Park, Sung Bae Lee, Sungkyu Lee et al. · Nature | 3 May 2006 | 1,731 |
| 22 | Signals from the lysosome: a control centre for cellular clearance and energy metabolism Carmine Settembre, Alessandro Fraldi, Diego Luis Medina et al. · Nature Reviews Molecular Cell Biology | 23 Apr 2013 | 1,731 |
| 23 | The Biogenesis of Lysosomes Stuart A. Kornfeld, Ira Mellman · Annual Review of Cell Biology | Nov 1989 | 1,592 |
| 24 | Safety and Efficacy of Recombinant Human α-Galactosidase A Replacement Therapy in Fabry's Disease Christine M. Eng, Nathalie Guffon, William Ross Wilcox et al. · New England Journal of Medicine | 5 Jul 2001 | 1,559 |
| 25 | Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis Henry J. Fuchs, Drucy Borowitz, David Høyrup Christiansen et al. · New England Journal of Medicine | 8 Sep 1994 | 1,543 |
| 26 | Lysosomes as dynamic regulators of cell and organismal homeostasis Andrea Ballabio, Juan S. Bonifacino · Nature Reviews Molecular Cell Biology | 25 Nov 2019 | 1,496 |
| 27 | LC3 conjugation system in mammalian autophagy Isei Tanida, Takashi Ueno, Eiki Kominami · The International Journal of Biochemistry & Cell Biology | 17 Aug 2004 | 1,487 |
| 28 | Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis Eugene D. Carstea et al. · Science | 11 Jul 1997 | 1,482 |
| 29 | Autophagy modulation as a potential therapeutic target for diverse diseases David Chaim Rubinsztein, Patrice Codogno, Beth Levine · Nature Reviews Drug Discovery | 31 Aug 2012 | 1,454 |
| 30 | Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I David J. Katzmann, Markus Babst, Scott D. Emr · Cell | Jul 2001 | 1,444 |
| 31 | Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds Robert G. Spiro · Glycobiology | Apr 2002 | 1,424 |
| 32 | Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL Seok Min Jin, Michael Lazarou, Chunxin Wang et al. · The Journal of Cell Biology | 29 Nov 2010 | 1,394 |
| 33 | Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies Joseph R. Mazzulli, You-Hai Xu, Ying Sun et al. · Cell | 27 Jun 2011 | 1,360 |
| 34 | COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum Charles K. Barlowe · Cell | 17 Jun 1994 | 1,343 |
| 35 | The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes Eisuke Itakura, Chieko Kishi‐Itakura, Noboru Mizushima · Cell | Dec 2012 | 1,325 |
| 36 | One step at a time: endoplasmic reticulum-associated degradation Shruthi Sridhar Vembar, Jeffrey L. Brodsky · Nature Reviews Molecular Cell Biology | 12 Nov 2008 | 1,316 |
| 37 | Enzyme Replacement Therapy in Fabry Disease Raphael Schiffmann, Jeffrey B. Kopp, Howard A. Austin et al. · JAMA | 6 Jun 2001 | 1,312 |
| 38 | Role of cholesterol and lipid organization in disease Frederick R. Maxfield, Ira A. Tabas · Nature | 30 Nov 2005 | 1,304 |
| 39 | Lysosomes and autophagy in cell death control Guido Kroemer, Marja Jäättelä · Nature reviews. Cancer | 20 Oct 2005 | 1,296 |
| 40 | Replacement Therapy for Inherited Enzyme Deficiency — Macrophage-Targeted Glucocerebrosidase for Gaucher's Disease Norman W. Barton, Roscoe O. Brady, James M. Dambrosia et al. · New England Journal of Medicine | 23 May 1991 | 1,273 |
| 41 | Niemann-Pick disease type C Marie Therese Vanier · Orphanet Journal of Rare Diseases | 3 Jun 2010 | 1,242 |
| 42 | Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations Ju‐Hyun Lee, Wai Haung Yu, Asok R. Kumar et al. · Cell | Jun 2010 | 1,233 |
| 43 | Fabry disease Dominique Paul Germain · Orphanet Journal of Rare Diseases | 2010 | 1,210 |
| 44 | The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion Saul Roseman · Chemistry and Physics of Lipids | Oct 1970 | 1,209 |
| 45 | Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase Alfredo Ramı́rez, André Heimbach, Jan Gründemann et al. · Nature Genetics | 10 Sep 2006 | 1,207 |
| 46 | Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention Edward A. Dennis, Jian Cao, Yuan‐Hao Hsu et al. · Chemical Reviews | 12 Sep 2011 | 1,193 |
| 47 | Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments Philippe Chavrier, Robert G. Parton, Hans Peter Hauri et al. · Cell | Jul 1990 | 1,177 |
| 48 | Epidemiology of mucopolysaccharidoses Shaukat Ali Khan, Hira Peracha, Diana Ballhausen et al. · Molecular Genetics and Metabolism | 29 May 2017 | 1,112 |
| 49 | Mannose 6-phosphate receptors: new twists in the tale Pradipta Ghosh, Nancy M. Dahms, Stuart A. Kornfeld · Nature Reviews Molecular Cell Biology | 28 Feb 2003 | 1,102 |
| 50 | The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy Naonobu Fujita, Takashi Itoh, Hiroko Omori et al. · Molecular Biology of the Cell | 5 Mar 2008 | 1,092 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.