Most cited papers in Macrophage Migration Inhibitory Factor
What are the most cited papers in Macrophage Migration Inhibitory Factor?
The most cited paper in Macrophage Migration Inhibitory Factor is "Matrix Metalloproteinases" (Hideaki Nagase, J. Frederick Woessner, 1999), with 3,917 citations. Next come "IL-10 inhibits cytokine production by activated macrophages" (2,923) and "Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver" (2,775).
Showing 50 of 99 papers. Every paper with more than 572 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Matrix Metalloproteinases Hideaki Nagase, J. Frederick Woessner · Journal of Biological Chemistry | Jul 1999 | 3,917 |
| 2 | IL-10 inhibits cytokine production by activated macrophages David Franklin Fiorentino, Albert Zlotnik, Tim R. Mosmann et al. · The Journal of Immunology | Dec 1991 | 2,923 |
| 3 | Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver Bruno Costa‐Silva et al. · Nature Cell Biology | 18 May 2015 | 2,775 |
| 4 | The role of tumour‐associated macrophages in tumour progression: implications for new anticancer therapies Lynne Bingle, Nicola Jane Brown, Claire E. Lewis · The Journal of Pathology | 22 Jan 2002 | 2,055 |
| 5 | Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. Carl Nathan, Henry W. Murray, Michael E. Wiebe et al. · The Journal of Experimental Medicine | Sep 1983 | 1,973 |
| 6 | Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 Evanna L. Mills et al. · Nature | 27 Mar 2018 | 1,933 |
| 7 | Macrophage migration inhibitory factor: a regulator of innate immunity Thierry Calandra, Thierry Roger · Nature reviews. Immunology | 18 Sep 2003 | 1,828 |
| 8 | Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature | 2002 | 1,647 |
| 9 | Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases Antonio Cuadrado, Ana Isabel Rojo, Geoffrey Wells et al. · Nature Reviews Drug Discovery | 4 Jan 2019 | 1,477 |
| 10 | Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes Alvin Ziying Lu, Venkat Giri Magupalli, Jianbin Ruan et al. · Cell | Mar 2014 | 1,377 |
| 11 | Role of Human Macrophage Polarization in Inflammation during Infectious Diseases Chiraz Atri, Fatma Zahra Guerfali, Dhafer Laouini · International Journal of Molecular Sciences | 19 Jun 2018 | 1,339 |
| 12 | MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment Jürgen Bernhagen, Regina M. Krohn, Hongqi Lue et al. · Nature Medicine | 15 Apr 2007 | 1,290 |
| 13 | MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily Michelle R. Bootcov, Asne R. Bauskin, Stella M. Valenzuela et al. · Proceedings of the National Academy of Sciences | 14 Oct 1997 | 1,188 |
| 14 | Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization Eleni Vergadi, Eleftheria Ieronymaki, Konstantina Lyroni et al. · The Journal of Immunology | 23 Jan 2017 | 1,186 |
| 15 | MIF Signal Transduction Initiated by Binding to CD74 Lin Leng, Christine Noel Metz, Yan Fang et al. · The Journal of Experimental Medicine | 2 Jun 2003 | 1,161 |
| 16 | MIF as a glucocorticoid-induced modulator of cytokine production Thierry Calandra, Jürgen Bernhagen, Christine Noel Metz et al. · Nature | Sep 1995 | 1,161 |
| 17 | Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells Veronika Groh, Alexander Steinle, Stefan Bauer et al. · Science | 13 Mar 1998 | 1,150 |
| 18 | Anti-inflammatory Agents: Present and Future Charles Anthony Dinarello · Cell | Mar 2010 | 1,108 |
| 19 | Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome Yiqing Yan, Wei Jiang, Lei Liu et al. · Cell | 2015 | 1,035 |
| 20 | Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB Veronika Groh, Rebecca L. Rhinehart, Heather Secrist et al. · Proceedings of the National Academy of Sciences | 8 Jun 1999 | 1,033 |
| 21 | Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation Martijn J.L. Bours, Els L.R. Swennen, Francesco Di Virgilio et al. · Pharmacology & Therapeutics | 20 Jun 2006 | 1,028 |
| 22 | Crystal Structure of the Tyrosine Phosphatase SHP-2 Peter Hof, Scott Pluskey, Sirano Dhe‐Paganon et al. · Cell | Feb 1998 | 1,013 |
| 23 | Abnormal Development of Peripheral Lymphoid Organs in Mice Deficient in Lymphotoxin Pietro De Togni, Joseph J. Goellner, Nancy H. Ruddle et al. · Science | 29 Apr 1994 | 1,007 |
| 24 | MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia J. Bernhagen, Thierry Calandra, Robert A. Mitchell et al. · Nature | 21 Oct 1993 | 1,005 |
| 25 | Glucocorticoid resistance in inflammatory diseases Peter John Barnes, Ian Michael Adcock · The Lancet | May 2009 | 985 |
| 26 | Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine Minu K. Srivastava, Pratima Sinha, Virginia K. Clements et al. · Cancer Research | 22 Dec 2009 | 954 |
| 27 | Cytokine patterns in patients with cancer: a systematic review Bodo E. Lippitz · The Lancet Oncology | 29 Apr 2013 | 929 |
| 28 | Modulation of Inflammation and Immunity by Cyclic AMP Henry R. Bourne, Yacob Weinstein, Kenneth L. Melmon et al. · Science | 5 Apr 1974 | 919 |
| 29 | POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS Igal Gery, Richard K. Gershon, Byron H. Waksman · The Journal of Experimental Medicine | Jul 1972 | 912 |
| 30 | A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration Werner Falk, Richard H. Goodwin, Edward J. Leonard · Journal of Immunological Methods | Apr 1980 | 904 |
| 31 | Galectin-1: a small protein with major functions Isabelle Camby, Marie Le Mercier, Florence Lefranc et al. · Glycobiology | 13 Jul 2006 | 896 |
| 32 | Crystal Structures of c-Src Reveal Features of Its Autoinhibitory Mechanism Wenqing Xu, Amish H. Doshi, Ming Lei et al. · Molecular Cell | May 1999 | 886 |
| 33 | Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment Vivian Barry-Hamilton et al. · Nature Medicine | Sep 2010 | 872 |
| 34 | Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. John B. Welsh, Lisa M. Sapinoso, Andrew I. Su et al. · PubMed | 15 Aug 2001 | 857 |
| 35 | Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1 Shigeki Chiba, Muhammad Baghdadi, Hisaya Akiba et al. · Nature Immunology | 29 Jul 2012 | 847 |
| 36 | Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis John T. Pesce, Thirumalai R. Ramalingam, Margaret M. Mentink‐Kane et al. · PLoS Pathogens | 9 Apr 2009 | 816 |
| 37 | Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity Lesley E. Smythies, Marty T. Sellers, Ronald H. Clements et al. · Journal of Clinical Investigation | 3 Jan 2005 | 796 |
| 38 | Cyclooxygenase-2 (COX-2) in Inflammatory and Degenerative Brain Diseases Luisa Minghetti · Journal of Neuropathology & Experimental Neurology | Sep 2004 | 785 |
| 39 | Inflammasomes in neuroinflammatory and neurodegenerative diseases Sofie Voet, Sahana Srinivasan, Mohamed Lamkanfi et al. · EMBO Molecular Medicine | 23 Apr 2019 | 778 |
| 40 | Novel strategies for the treatment of sepsis Niels C. Riedemann, Ren-Feng Guo, Peter A. Ward · Nature Medicine | 30 Apr 2003 | 778 |
| 41 | Inflammatory Resolution: new opportunities for drug discovery Derek William Gilroy, Toby Lawrence, Mauro Perretti et al. · Nature Reviews Drug Discovery | May 2004 | 774 |
| 42 | Regulation of the immune response by prostaglandins James S. Goodwin, David R. Webb · Clinical Immunology and Immunopathology | 1980 | 770 |
| 43 | Methionine‐deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF‐I and insulin levels, and increases hepatocyte MIF levels and stress resistance Richard A. Miller, Gretchen Buehner, Yayi Chang et al. · Aging Cell | 13 Apr 2005 | 755 |
| 44 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion Yu‐Hwa Huang et al. · Nature | 24 Oct 2014 | 740 |
| 45 | Protection from septic shock by neutralization of macrophage migration inhibitory factor Thierry Calandra, Bernd Echtenacher, Didier Le Roy et al. · Nature Medicine | Feb 2000 | 728 |
| 46 | Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology De’Broski R. Herbert, Christoph Hölscher, Markus Mohrs et al. · Immunity | May 2004 | 725 |
| 47 | A significant part of macrophage-derived growth factor consists of at least two forms of PDGF Kentaro Shimokado, Elaine W. Raines, David K. Madtes et al. · Cell | Nov 1985 | 721 |
| 48 | Hepatic macrophages in liver homeostasis and diseases-diversity, plasticity and therapeutic opportunities Yankai Wen, Joeri Lambrecht, Cynthia Ju et al. · Cellular and Molecular Immunology | 12 Oct 2020 | 712 |
| 49 | Role of MHC Gene Products in Immune Regulation Baruj Benacerraf · Science | 12 Jun 1981 | 701 |
| 50 | Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity Hugh F. Pross, Malcolm G. Baines, Peter Rubin et al. · Journal of Clinical Immunology | 1981 | 697 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.