Most cited papers in Marine Toxins and Detection Methods
What are the most cited papers in Marine Toxins and Detection Methods?
The most cited paper in Marine Toxins and Detection Methods is "The Ecological Role of Water-Column Microbes in the Sea" (F Azam, Tom Fenchel, JG Field et al., 1983), with 5,476 citations. Next come "Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle" (1,705) and "Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics" (1,699).
Showing 50 of 100 papers. Every paper with more than 429 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Ecological Role of Water-Column Microbes in the Sea F Azam, Tom Fenchel, JG Field et al. · Marine Ecology Progress Series | 1983 | 5,476 |
| 2 | Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle Victoria M. Bolotina, Soheil Najibi, James J. Palacino et al. · Nature | Apr 1994 | 1,705 |
| 3 | Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics Corinna Bialojan, Akira Takai · Biochemical Journal | 15 Nov 1988 | 1,699 |
| 4 | Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants Carol MacKintosh, Kenneth A. Beattie, Susanne Klumpp et al. · FEBS Letters | 21 May 1990 | 1,665 |
| 5 | Okadaic acid: a new probe for the study of cellular regulation Philip Cohen, Charles F.B. Holmes, Yasumasa Tsukitani · Trends in Biochemical Sciences | Mar 1990 | 1,397 |
| 6 | The Effects of Harmful Algal Blooms on Aquatic Organisms Jan H. Landsberg · Reviews in Fisheries Science | Apr 2002 | 1,368 |
| 7 | Harmful algal blooms: Their ecophysiology and general relevance to phytoplankton blooms in the sea Theodore J. Smayda · Limnology and Oceanography | Jul 1997 | 1,276 |
| 8 | Hydrogen Peroxide: A Signaling Messenger James R. Stone, Suping Yang · Antioxidants and Redox Signaling | Mar 2006 | 1,177 |
| 9 | Cyanobacterial toxins: risk management for health protection Geoffrey A. Codd, Louise F. Morrison, James S. Metcalf · Toxicology and Applied Pharmacology | 30 Jul 2004 | 1,163 |
| 10 | Progress in Understanding Harmful Algal Blooms: Paradigm Shifts and New Technologies for Research, Monitoring, and Management Donald Mark Anderson, Allan Cembella, Gustaaf Marinus Hallegraeff · Annual Review of Marine Science | 2 Mar 2011 | 1,159 |
| 11 | A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons Armen N. Akopian, Lucia G. Sivilotti, John N. Wood · Nature | 1996 | 1,119 |
| 12 | The Toxins of Cyanobacteria Wayne W. Carmichael · Scientific American | 1994 | 1,099 |
| 13 | Tetrodotoxin Blockage of Sodium Conductance Increase in Lobster Giant Axons Toshio Narahashi, John W. Moore, William R. Scott · The Journal of General Physiology | May 1964 | 1,087 |
| 14 | Calyculin A and okadaic acid: Inhibitors of protein phosphatase activity H. Ishihara, Bryan L Martin, David L. Brautigan et al. · Biochemical and Biophysical Research Communications | Mar 1989 | 1,057 |
| 15 | BIOCHEMISTRY OF OXYGEN TOXICITY Enrique Cadenas · Annual Review of Biochemistry | Jun 1989 | 1,036 |
| 16 | Health Effects of Toxin-Producing Cyanobacteria: “The CyanoHABs” Wayne W. Carmichael · Human and Ecological Risk Assessment An International Journal | Sep 2001 | 991 |
| 17 | State of knowledge and concerns on cyanobacterial blooms and cyanotoxins Sylvain Merel, David B. Walker, Ruth Chicana et al. · Environment International | 24 Jul 2013 | 984 |
| 18 | Existence of distinct sodium channel messenger RNAs in rat brain Masaharu Noda, Takayuki Ikeda, Toshiaki Kayano et al. · Nature | Mar 1986 | 909 |
| 19 | Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin Peter S. Spencer, Peter B. Nunn, Jacques Hugon et al. · Science | 31 Jul 1987 | 897 |
| 20 | IDENTIFICATION OF GROUP‐ AND STRAIN‐SPECIFIC GENETIC MARKERS FOR GLOBALLY DISTRIBUTED ALEXANDRIUM (DINOPHYCEAE). II. SEQUENCE ANALYSIS OF A FRAGMENT OF THE LSU rRNA GENE 1 Christopher A. Scholin, Michel Herzog, Mitchell L. Sogin et al. · Journal of Phycology | Dec 1994 | 891 |
| 21 | the toxicology of microcystins REX M. C. DAWSON · Toxicon | Jul 1998 | 878 |
| 22 | Flow Cytometric Analysis of Respiratory Burst Activity in Phagocytes With Hydroethidine and 2′,7′-Dichlorofluorescin Gregor Rothe, Günter Valet · Journal of Leukocyte Biology | May 1990 | 875 |
| 23 | Bioluminescence in the Sea Steven H. D. Haddock, Mark A. Moline, James F. Case · Annual Review of Marine Science | 14 Dec 2009 | 865 |
| 24 | Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism Timothy Haystead, Alastair T.R. Sim, David Carling et al. · Nature | 1989 | 848 |
| 25 | Marine algal toxins: origins, health effects, and their increased occurrence. Frances M. Van Dolah · Environmental Health Perspectives | Mar 2000 | 840 |
| 26 | Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Stephen L. Archer, Jiehuan Huang, Václav Hampl et al. · Proceedings of the National Academy of Sciences | 2 Aug 1994 | 823 |
| 27 | Mortality of sea lions along the central California coast linked to a toxic diatom bloom Christopher A. Scholin et al. · Nature | 2000 | 819 |
| 28 | Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR Rie Nishiwaki‐Matsushima, Tetsuya Ohta, Shinji Nishiwaki et al. · Journal of Cancer Research and Clinical Oncology | Jun 1992 | 808 |
| 29 | Calcium channel characteristics conferred on the sodium channel by single mutations Stefan H. Heinemann, Heinrich Terlau, Walter Stühmer et al. · Nature | Apr 1992 | 792 |
| 30 | Neurotoxic Alkaloids: Saxitoxin and Its Analogs Maria Wiese, Paul Michael D'Agostino, Troco Kaan Mihali et al. · Marine Drugs | 20 Jul 2010 | 773 |
| 31 | Latrunculins: Novel Marine Toxins That Disrupt Microfilament Organization in Cultured Cells Ilan Spector, Nava R. Shochet, Yoel Kashman et al. · Science | 4 Feb 1983 | 770 |
| 32 | An Outbreak of Toxic Encephalopathy Caused by Eating Mussels Contaminated with Domoic Acid Trish M. Perl, Lucie Bédard, Tom Kosatsky et al. · New England Journal of Medicine | 21 Jun 1990 | 736 |
| 33 | Toxins of cyanobacteria Marian E. van Apeldoorn, Hans P. van Egmond, Gerrit J. A. Speijers et al. · Molecular Nutrition & Food Research | 29 Dec 2006 | 727 |
| 34 | The globally distributed genus Alexandrium: Multifaceted roles in marine ecosystems and impacts on human health Donald Mark Anderson, Tilman J. Alpermann, Allan Cembella et al. · Harmful Algae | 26 Oct 2011 | 721 |
| 35 | Structure, regulation and evolution of Nox‐family NADPH oxidases that produce reactive oxygen species Hideki Sumimoto · FEBS Journal | 30 May 2008 | 719 |
| 36 | A Review of the Effects of Algal Blooms on Shellfish and Aquaculture Sandra E. Shumway · Journal of the World Aquaculture Society | Jun 1990 | 716 |
| 37 | Synthetic routes to tetrahydrofuran, tetrahydropyran, and spiroketal units of polyether antibiotics and a survey of spiroketals of other natural products Taryn L. B. Boivin · Tetrahedron | 1987 | 686 |
| 38 | Harmful algal blooms and eutrophication: Examining linkages from selected coastal regions of the United States Donald Mark Anderson, JoAnn M. Burkholder, William P. Cochlan et al. · Harmful Algae | 7 Sep 2008 | 682 |
| 39 | Escalating Worldwide use of Urea – A Global Change Contributing to Coastal Eutrophication Patricia M. Glibert, John A. Harrison, Cynthia A. Heil et al. · Biogeochemistry | Feb 2006 | 675 |
| 40 | The insidious effect of diatoms on copepod reproduction Antonio Miralto, Giovanni Battista Barone, Giovanna Romano et al. · Nature | Nov 1999 | 673 |
| 41 | Approaches to monitoring, control and management of harmful algal blooms (HABs) Donald Mark Anderson · Ocean & Coastal Management | 8 Apr 2009 | 664 |
| 42 | Harmful algal blooms: causes, impacts and detection Kevin G. Sellner, Gregory J. Doucette, Gary J. Kirkpatrick · Journal of Industrial Microbiology & Biotechnology | Jul 2003 | 664 |
| 43 | Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters Linda A. Lawton, Christine Edwards, Geoffrey A. Codd · The Analyst | 1994 | 663 |
| 44 | Diarrhetic shellfish toxins T. Yasumoto, Michio Murata, Y. Oshima et al. · Tetrahedron | 1985 | 645 |
| 45 | Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam Paul Alan Cox, Sandra Anne Banack, Susan J. Murch · Proceedings of the National Academy of Sciences | 11 Nov 2003 | 635 |
| 46 | Harmful algal blooms: A climate change co-stressor in marine and freshwater ecosystems Andrew W. Griffith, Christopher J. Gobler · Harmful Algae | 21 May 2019 | 611 |
| 47 | Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter. Masami Suganuma, Hirota Fujiki, Hiroko Suguri et al. · Proceedings of the National Academy of Sciences | Mar 1988 | 603 |
| 48 | Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases. Richard E. Honkanen, Jean Zwiller, Richard E. Moore et al. · Journal of Biological Chemistry | Nov 1990 | 592 |
| 49 | An unprecedented coastwide toxic algal bloom linked to anomalous ocean conditions Ryan M. McCabe, Barbara M. Hickey, Raphael M. Kudela et al. · Geophysical Research Letters | 20 Sep 2016 | 585 |
| 50 | Inhibition of protein phosphatases by microcystis and nodularin associated with hepatotoxicity Shigeru Yoshizawa, Rie Matsushima, Mariyo F. Watanabe et al. · Journal of Cancer Research and Clinical Oncology | Nov 1990 | 584 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.