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Most cited papers in Mast cells and histamine

What are the most cited papers in Mast cells and histamine?

The most cited paper in Mast cells and histamine is "Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors" (Seiichi Hirota, Koji Isozaki, Yasuhiro Moriyama et al., 1998), with 4,517 citations. Next come "A fluorometric method for determination of oxidized and reduced glutathione in tissues" (4,127) and "Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor" (2,507).

Showing 50 of 100 papers. Every paper with more than 846 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors Seiichi Hirota, Koji Isozaki, Yasuhiro Moriyama et al. · Science 23 Jan 1998 4,517
2 A fluorometric method for determination of oxidized and reduced glutathione in tissues Paul J. Hissin, Russell Hilf · Analytical Biochemistry Jul 1976 4,127
3 Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor Carl‐Henrik Heldin, Bengt Westermark · Physiological Reviews Review 10 Jan 1999 2,507
4 Inositol phospholipids and cell surface receptor function Robert Hall Michell · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes Mar 1975 2,479
5 Establishment and characterization of a human histiocytic lymphoma cell line (U‐937) Christer Sundström, Kenneth Nilsson · International Journal of Cancer 15 May 1976 2,436
6 Chronic graft-versus-host syndrome in man Howard M. Shulman, Keith M. Sullivan, Paul L. Weiden et al. · The American Journal of Medicine Aug 1980 2,436
7 mTOR signaling at a glance Mathieu Laplante, David M. Sabatini · Journal of Cell Science Open access 7 Oct 2009 2,182
8 Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Danny Liaw, Debbie J. Marsh, Jing Li et al. · Nature Genetics May 1997 2,102
9 New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway Lewis C. Cantley, Benjamin G. Neel · Proceedings of the National Academy of Sciences Open access 13 Apr 1999 2,041
10 Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling Ken Inoki, Yong Li, Tian Xu et al. · Genes & Development Open access 17 Jul 2003 1,947
11 An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 Carson C. Thoreen, Seong Anthony Woo Kang, Jae Won Chang et al. · Journal of Biological Chemistry Open access 16 Jan 2009 1,844
12 The development of allergic inflammation Stephen Joseph Galli, Mindy Tsai, Adrian Martin Piliponsky · Nature Open access Jul 2008 1,828
13 IgE and mast cells in allergic disease Stephen Joseph Galli, Mindy Tsai · Nature Medicine Open access May 2012 1,810
14 „Natural” killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype Rolf W. Kiessling, Eva Klein, Hans Wigzell · European Journal of Immunology Feb 1975 1,806
15 Mast cells D D Metcalfe, Dana Baram, Yoseph A. Mekori · Physiological Reviews Oct 1997 1,723
16 Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon Gerald P. Morris, Paul L. Beck, Margaret S. Herridge et al. · Gastroenterology Feb 1989 1,718
17 IgE, mast cells, basophils, and eosinophils Kelly D. Stone, Calman Prussin, Dean D. Metcalfe · Journal of Allergy and Clinical Immunology Open access Feb 2010 1,684
18 Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor Jean‐Michel Arrang, Monique Garbarg, Jean‐Charles Schwartz · Nature Apr 1983 1,578
19 METHOD FOR THE DETERMINATION OF HEXOSAMINES IN TISSUES Norman F. Boas · Journal of Biological Chemistry Open access Oct 1953 1,533
20 Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose Christine H. Chung, Beloo Mirakhur, Emily W. Chan et al. · New England Journal of Medicine Open access 12 Mar 2008 1,517
21 Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome Giovanni Barbara, Vincenzo Stanghellini, Roberto De Giorgio et al. · Gastroenterology Open access 25 Feb 2004 1,475
22 Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor Krisztina M. Zsebo, David A. Williams, E N Geissler et al. · Cell Oct 1990 1,429
23 The SYK tyrosine kinase: a crucial player in diverse biological functions Attila Mócsai, Jürgen Ruland, Victor L. J. Tybulewicz · Nature reviews. Immunology ReviewOpen access 14 May 2010 1,401
24 Scleroderma Armando Gabrielli, Enrico Vittorio Avvedimento, Thomas M. Krieg · New England Journal of Medicine 6 May 2009 1,391
25 The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus Benoı̂t Chabot, Dennis A. Stephenson, Verne M. Chapman et al. · Nature Sep 1988 1,377
26 Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma William W. Busse, Jonathan Corren, Bobby Quentin Lanier et al. · Journal of Allergy and Clinical Immunology Open access Aug 2001 1,310
27 Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions Benjamin D. McNeil, Priyanka Pundir, Sonya Meeker et al. · Nature Open access 16 Dec 2014 1,301
28 Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors Elisabeth Buchdunger, Catherine L. Cioffi, Norman M. Law et al. · Journal of Pharmacology and Experimental Therapeutics Oct 2000 1,284
29 Mast cells in the development of adaptive immune responses Stephen Joseph Galli, Susumu Nakae, Mindy Tsai · Nature Immunology 20 Jan 2005 1,281
30 Recurrent BRAF mutations in Langerhans cell histiocytosis Gayane Badalian‐Very, Jo‐Anne Vergilio, Barbara A. Degar et al. · Blood Open access 2 Jun 2010 1,255
31 The TSC1–TSC2 complex: a molecular switchboard controlling cell growth Jingxiang Huang, Brendan D. Manning · Biochemical Journal Open access 14 May 2008 1,253
32 Mast-Cell Infiltration of Airway Smooth Muscle in Asthma Christopher Edward Brightling, Peter Bradding, Fiona A. Symon et al. · New England Journal of Medicine Open access 30 May 2002 1,243
33 MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances Stephen Joseph Galli, Janet Kalesnikoff, Michele A. Grimbaldeston et al. · Annual Review of Immunology Review 11 Feb 2005 1,237
34 Histamine in the Nervous System Helmut L. Haas, Olga A. Sergeeva, Oliver Selbach · Physiological Reviews Review Jul 2008 1,234
35 The Multiple Roles of PTEN in Tumor Suppression Antonio Di Cristofano, Pier Paolo Pandolfi · Cell Open access Feb 2000 1,213
36 DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival Timothy R. Peterson, Mathieu Laplante, Carson C. Thoreen et al. · Cell Open access May 2009 1,211
37 LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS Jacques Benveniste, Peter M. Henson, Charles G. Cochrane · The Journal of Experimental Medicine Open access Dec 1972 1,208
38 The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus Eric Jinsheng Huang, Karl H. Nocka, David R. Beier et al. · Cell Open access Oct 1990 1,192
39 MITF: master regulator of melanocyte development and melanoma oncogene Carmit Levy, Mehdi Khaled, David E. Fisher · Trends in Molecular Medicine Review 9 Aug 2006 1,182
40 Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores Marshall Plaut, Jacalyn H. Pierce, Cynthia J. Watson et al. · Nature May 1989 1,179
41 Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies Yukiya Yamamoto · Blood 15 Apr 2001 1,153
42 Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α Ravi Malaviya, Teruo Ikeda, Elaine Ross et al. · Nature May 1996 1,125
43 mTOR as a central hub of nutrient signalling and cell growth Joungmok Kim, Kun‐Liang Guan · Nature Cell Biology 26 Oct 2018 1,124
44 The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2 Greg M. Delgoffe, Kristen N. Pollizzi, Adam Tully Waickman et al. · Nature Immunology Open access 27 Feb 2011 1,120
45 Diagnostic criteria and classification of mastocytosis: a consensus proposal Peter Valent, Hans‐P. Horny, Luís Escribano et al. · Leukemia Research Jul 2001 1,117
46 Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells Tim R. Mosmann, Robert L. Coffman · Advances in immunology Book chapter 1989 1,116
47 Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria Marcus Maurer, Karin E. Rosén, Hsin-Ju Hsieh et al. · New England Journal of Medicine Open access 24 Feb 2013 1,105
48 Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2 Hiroyuki Hirai, Kazuya Tanaka, Osamu Yoshie et al. · The Journal of Experimental Medicine Open access 15 Jan 2001 1,100
49 Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2 Morris E. Feldman, Beth Apsel, Aino Uotila et al. · PLoS Biology Open access 7 Feb 2009 1,095
50 Lessons for management of anaphylaxis from a study of fatal reactions Pumphrey · Clinical & Experimental Allergy Aug 2000 1,095

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.