Most cited papers in Microfluidic and Bio-sensing Technologies
What are the most cited papers in Microfluidic and Bio-sensing Technologies?
The most cited paper in Microfluidic and Bio-sensing Technologies is "Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches" (Owen P. Hamill, Alain Marty, Erwin Neher et al., 1981), with 18,543 citations. Next come "Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets" (8,040) and "Observation of a single-beam gradient force optical trap for dielectric particles" (7,072).
Showing 50 of 100 papers. Every paper with more than 1,203 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology | Aug 1981 | 18,543 |
| 2 | Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell | May 2015 | 8,040 |
| 3 | Observation of a single-beam gradient force optical trap for dielectric particles Arthur Ashkin, J. M. Dziedzic, John E. Bjorkholm et al. · Optics Letters | May 1986 | 7,072 |
| 4 | Applications of magnetic nanoparticles in biomedicine Quentin A. Pankhurst, Joan Connolly, Stephen K Jones et al. · Journal of Physics D Applied Physics | 19 Jun 2003 | 5,871 |
| 5 | Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane) David C. Duffy, J. Cooper McDonald, Olivier J. A. Schueller et al. · Analytical Chemistry | 24 Oct 1998 | 5,316 |
| 6 | A revolution in optical manipulation David G. Grier · Nature | Aug 2003 | 5,145 |
| 7 | A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry Ildo Nicoletti, Graziella Migliorati, Maria Cristina Pagliacci et al. · Journal of Immunological Methods | Jun 1991 | 4,648 |
| 8 | Microfluidics: Fluid physics at the nanoliter scale Todd M. Squires, Stephen R. Quake · Reviews of Modern Physics | 6 Oct 2005 | 4,383 |
| 9 | Hydrodynamics of soft active matter Maria Cristina Marchetti, Jean‐François Joanny, Sriraṁ Ramaswamy et al. · Reviews of Modern Physics | 19 Jul 2013 | 4,254 |
| 10 | The analysis of electrode impedances complicated by the presence of a constant phase element G.J. Brug, A.L.G. van den Eeden, M. Sluyters‐Rehbach et al. · Journal of Electroanalytical Chemistry | Sep 1984 | 3,706 |
| 11 | Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip Howard A. Stone, Abraham Duncan Stroock, Armand Ajdari · Annual Review of Fluid Mechanics | 7 Apr 2003 | 3,655 |
| 12 | Isolation of rare circulating tumour cells in cancer patients by microchip technology Sunitha Nagrath, Lecia Van Dam Sequist, Shyamala Maheswaran et al. · Nature | Dec 2007 | 3,572 |
| 13 | Chaotic Mixer for Microchannels Abraham Duncan Stroock, Stephan K. W. Dertinger, Armand Ajdari et al. · Science | 25 Jan 2002 | 3,431 |
| 14 | Characterization of individual polynucleotide molecules using a membrane channel John J. Kasianowicz, Eric Brandin, Daniel Branton et al. · Proceedings of the National Academy of Sciences | 26 Nov 1996 | 3,401 |
| 15 | The dielectric properties of biological tissues: I. Literature survey C Gabriel, S Gabriel, E Corthout · Physics in Medicine and Biology | Nov 1996 | 3,169 |
| 16 | Bacterial Persistence as a Phenotypic Switch Nathalie Q. Balaban, Jack Merrin, Remy Chait et al. · Science | 12 Aug 2004 | 3,114 |
| 17 | Miniaturized total chemical analysis systems: A novel concept for chemical sensing A. Manz, N. Graber, H. Michael. Widmer · Sensors and Actuators B Chemical | 1990 | 3,107 |
| 18 | Active Particles in Complex and Crowded Environments Clemens Bechinger, Roberto Di Leonardo, Hartmut Löwen et al. · Reviews of Modern Physics | 23 Nov 2016 | 3,049 |
| 19 | The present and future role of microfluidics in biomedical research Eric K. Sackmann, Anna L. Fulton, David J. Beebe · Nature | Mar 2014 | 3,003 |
| 20 | Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules Steven B. Smith, Yujia Cui, Carlos Bustamante · Science | 9 Feb 1996 | 2,798 |
| 21 | Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases W. Jeffrey Allard, Jeri Matera, Michael Craig Miller et al. · Clinical Cancer Research | 15 Oct 2004 | 2,544 |
| 22 | The hydrodynamics of swimming microorganisms Eric Lauga, Thomas R. Powers · Reports on Progress in Physics | 25 Aug 2009 | 2,530 |
| 23 | Optical trapping and manipulation of single cells using infrared laser beams Arthur Ashkin, J. M. Dziedzic, Tsuyoshi Yamane · Nature | Dec 1987 | 2,317 |
| 24 | Self-Motile Colloidal Particles: From Directed Propulsion to Random Walk Jonathan R. Howse, Richard Jones, Anthony J. Ryan et al. · Physical Review Letters | 27 Jul 2007 | 2,263 |
| 25 | Microfluidic Large-Scale Integration Todd Thorsen, Sebastian J. Maerkl, Stephen R. Quake · Science | 17 Oct 2002 | 2,245 |
| 26 | Tweezers with a twist Miles J. Padgett, Richard W Bowman · Nature Photonics | 31 May 2011 | 2,236 |
| 27 | Micro Total Analysis Systems. 1. Introduction, Theory, and Technology Darwin R. Reyes, Dimitri Iossifidis, Pierre-Alain Auroux et al. · Analytical Chemistry | 17 May 2002 | 2,196 |
| 28 | Optical Trapping and Manipulation of Viruses and Bacteria Arthur Ashkin, J. M. Dziedzic · Science | 20 Mar 1987 | 2,192 |
| 29 | Optical trapping Keir C. Neuman, Steven M. Block · Review of Scientific Instruments | Sep 2004 | 2,171 |
| 30 | Catalytic Nanomotors: Autonomous Movement of Striped Nanorods Walter F. Paxton, Kevin C. Kistler, Christine C. Olmeda et al. · Journal of the American Chemical Society | 21 Sep 2004 | 2,131 |
| 31 | Optical Spin-to-Orbital Angular Momentum Conversion in Inhomogeneous Anisotropic Media Lorenzo Marrucci, Carlo Manzo, Domenico Paparo · Physical Review Letters | 28 Apr 2006 | 2,130 |
| 32 | Cells on chips J. El-Ali, Peter Karl Sorger, Klavs F. Jensen · Nature | 26 Jul 2006 | 2,095 |
| 33 | Scattering theory of waves and particles GREGORY A. BREIT · Journal of the Franklin Institute | Oct 1967 | 2,066 |
| 34 | Thermal ablation of tumours: biological mechanisms and advances in therapy Katrina F. Chu, Damian Edward Dupuy · Nature reviews. Cancer | 24 Feb 2014 | 2,012 |
| 35 | Cells lying on a bed of microneedles: An approach to isolate mechanical force John L. Tan, Joe Tien, Dana M. Pirone et al. · Proceedings of the National Academy of Sciences | 27 Jan 2003 | 1,979 |
| 36 | Microfluidic diagnostic technologies for global public health Paul Yager, Thayne L. Edwards, Elain S. Fu et al. · Nature | 26 Jul 2006 | 1,971 |
| 37 | Direct observation of kinesin stepping by optical trapping interferometry Karel Svoboda, Christoph F. Schmidt, Bruce J. Schnapp et al. · Nature | Oct 1993 | 1,936 |
| 38 | Transport phenomena in nanofluidics Reto B. Schoch, Jongyoon Han, Philippe Renaud · Reviews of Modern Physics | 17 Jul 2008 | 1,936 |
| 39 | THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO TR Bradley, D Metcalf · Immunology and Cell Biology | Jun 1966 | 1,933 |
| 40 | Effect of skin impedance on image quality and variability in electrical impedance tomography: a model study K Boone, David S. Holder · Medical & Biological Engineering & Computing | Sep 1996 | 1,928 |
| 41 | Microscopic artificial swimmers Rémi Dreyfus, Jean Baudry, Marcus L. Roper et al. · Nature | Oct 2005 | 1,873 |
| 42 | Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays Ao Chen et al. · Cell | May 2022 | 1,872 |
| 43 | Lab-on-a-chip: microfluidics in drug discovery Petra Stephanie Dittrich, A. Manz · Nature Reviews Drug Discovery | Mar 2006 | 1,850 |
| 44 | From 3D cell culture to organs-on-chips Dongeun Huh, Geraldine A. Hamilton, Donald E. Ingber · Trends in Cell Biology | 26 Oct 2011 | 1,845 |
| 45 | A review of micropumps Daniel J. Laser, Juan Gabriel Santiago · Journal of Micromechanics and Microengineering | 20 Apr 2004 | 1,841 |
| 46 | Physics and Applications of Microfluidics in Biology David J. Beebe, Glennys A. Mensing, Glenn M. Walker · Annual Review of Biomedical Engineering | 28 Jul 2002 | 1,803 |
| 47 | Biological Applications of Optical Forces Karel Svoboda, Stephan Block · Annual Review of Biophysics and Biomolecular Structure | Jun 1994 | 1,801 |
| 48 | Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip D. Jed Harrison, Karl Fluri, Kurt Seiler et al. · Science | 13 Aug 1993 | 1,798 |
| 49 | Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow Hyun Jung Kim, Dongeun Huh, Geraldine A. Hamilton et al. · Lab on a Chip | 2012 | 1,747 |
| 50 | Continuous inertial focusing, ordering, and separation of particles in microchannels Dino Di Carlo, Daniel Irimia, Ronald G. Tompkins et al. · Proceedings of the National Academy of Sciences | 19 Nov 2007 | 1,737 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.