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Topic · Biomedical Engineering

Microfluidic and Bio-sensing Technologies

Microfluidic and Bio-sensing Technologies is a research topic within Biomedical Engineering. Science Explorer counts 41k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the use of microfluidic techniques for manipulating and separating particles, cells, and biological entities. The papers cover a wide range of methods including acoustic manipulation, dielectrophoresis, inertial focusing, and continuous flow separation. These techniques have applications in areas such as cell sorting, lab-on-a-chip devices, and impedance spectroscopy.

  • Microfluidics
  • Particle Separation
  • Acoustic Manipulation
  • Dielectrophoresis
  • Cell Sorting
  • Inertial Focusing
  • Lab-on-a-Chip
  • Impedance Spectroscopy
  • Continuous Flow
  • Acoustofluidics
Research works
41k
fractional, since 1950
In the world top 10%
4k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-7%
the tick is no change
Largest producer
China
36% of the 10 largest, 2022-now
Microfluidic and Bio-sensing Technologies

Which countries lead Microfluidic and Bio-sensing Technologies research?

By volume, China and the United States publish the most (1.8k and 1.2k works in 2022-now).

By volume, 2022-now

  1. 1 China 1.8k works
  2. 2 United States 1.2k works
  3. 3 India 380 works
  4. 4 Japan 371 works
  5. 5 Germany 318 works
  6. 6 France 236 works
  7. 7 United Kingdom 231 works
  8. 8 South Korea 191 works
  9. 9 Italy 172 works
  10. 10 Iran 145 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 35.5%United States: 23.9%India: 7.5%Japan: 7.4%6 others listed: 25.7%36%largest
China1,789 · 35.5%United States1,207 · 23.9%India380 · 7.5%Japan371 · 7.4%6 others listed1,293 · 25.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Microfluidic and Bio-sensing Technologies research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Microfluidic and Bio-sensing Technologies research, followed by Centre National de la Recherche Scientifique and Zhejiang University.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 141 works
  2. 2 Centre National de la Recherche ScientifiqueFrance 109 works
  3. 3 Zhejiang UniversityChina 49 works
  4. 4 Russian Academy of SciencesRussia 46 works
  5. 5 Tianjin UniversityChina 41 works
  6. 6 Shanghai Jiao Tong UniversityChina 38 works
  7. 7 Xi'an Jiaotong UniversityChina 37 works
  8. 8 Tsinghua UniversityChina 34 works
  9. 9 Harbin Institute of TechnologyChina 32 works
  10. 10 Southeast UniversityChina 30 works

Who are the leading researchers in Microfluidic and Bio-sensing Technologies?

The most-cited researchers publishing on Microfluidic and Bio-sensing Technologies include Zhong Lin Wang, Yury G. Gogotsi and Róbert Langer.

  1. 1 Zhong Lin Wang United States 491k citations
  2. 2 Yury G. Gogotsi United States 313k citations
  3. 3 Róbert Langer United States 303k citations
  4. 4 George M. Whitesides United States 267k citations
  5. 5 Wei Huang China 267k citations
  6. 6 Gordon Brent Mills United States 265k citations
  7. 7 Yi Ping Cui United States 261k citations
  8. 8 Ben Zhong Tang China 261k citations
  9. 9 Kenneth J. Livak United States 260k citations
  10. 10 Hans C. Clevers Netherlands 260k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Microfluidic and Bio-sensing Technologies?

The most cited paper in Microfluidic and Bio-sensing Technologies is "Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches" (Owen P. Hamill, Alain Marty, Erwin Neher et al., 1981), with 18,543 citations. Next come "Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets" (8,040) and "Observation of a single-beam gradient force optical trap for dielectric particles" (7,072).

Most cited papers
#PaperReleasedCitations
1 Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology Aug 1981 18,543
2 Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell Open access May 2015 8,040
3 Observation of a single-beam gradient force optical trap for dielectric particles Arthur Ashkin, J. M. Dziedzic, John E. Bjorkholm et al. · Optics Letters May 1986 7,072
4 Applications of magnetic nanoparticles in biomedicine Quentin A. Pankhurst, Joan Connolly, Stephen K Jones et al. · Journal of Physics D Applied Physics 19 Jun 2003 5,871
5 Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane) David C. Duffy, J. Cooper McDonald, Olivier J. A. Schueller et al. · Analytical Chemistry 24 Oct 1998 5,316
All 100 most cited papers, with filters and sorting

Where is Microfluidic and Bio-sensing Technologies research done?

The largest centres of Microfluidic and Bio-sensing Technologies research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Kharagpur and Gwangju.

Largest cities, 2022-now

  1. 1 BeijingChina 293 works
  2. 2 ShanghaiChina 147 works
  3. 3 TokyoJapan 129 works
  4. 4 NanjingChina 124 works
  5. 5 Xi'anChina 108 works
  6. 6 ParisFrance 100 works
  7. 7 HangzhouChina 94 works
  8. 8 TehranIran 82 works
  9. 9 SeoulSouth Korea 76 works
  10. 10 GuangzhouChina 73 works

Where it is the local speciality

  1. KharagpurIN · 20.3 works6.4×
  2. GwangjuKR · 20.4 works6.0×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Microfluidic and Bio-sensing Technologies than the world average.

See Microfluidic and Bio-sensing Technologies on the map

Where is the best place to study Microfluidic and Bio-sensing Technologies?

Among universities, judged by research, Harvard University, Zhejiang University and ETH Zurich score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 16.26%fractional works in this field (log) →share of work in the world top 10% →Harvard UniversityETH ZurichZhejiang UniversityTianjin University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 70.330.2%1.6×30 -12.2%
2Zhejiang UniversityChina 59.810.6%3.2×49 +18.1%
3ETH ZurichSwitzerland 57.816.4%6.7×26 -23.4%
4Tianjin UniversityChina 57.19.2%6.0×41 +24.3%
5Shanghai Jiao Tong UniversityChina 56.415.7%2.4×38 +12.3%
6Southeast UniversityChina 55.217.3%3.6×30 +3.1%
7University of Chinese Academy of SciencesChina 54.916.1%2.7×25 +37.1%
8Xi'an Jiaotong UniversityChina 53.510.2%3.8×37 +34.6%
9Wuhan UniversityChina 52.823.1%2.1×17 +17.4%
10Nanjing UniversityChina 52.413.8%4.9×26 +11.6%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Microfluidic and Bio-sensing Technologies, country by country

Is Microfluidic and Bio-sensing Technologies research growing?

Output in 2022-2025 was 7% lower than in 2018-2021, peaking in 2019.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Microfluidic and Bio-sensing Technologies as a percentage of every work published that year, 0.027% in 2024.

still counting0.020%0.040%0.060%Microfluidic and Bio-sensing Technologies0.025% in 202519801990200020102020

Fractional works of Microfluidic and Bio-sensing Technologies over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Microfluidic and Bio-sensing Technologies9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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