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Most cited papers in Nanoparticle-Based Drug Delivery

What are the most cited papers in Nanoparticle-Based Drug Delivery?

The most cited paper in Nanoparticle-Based Drug Delivery is "Nanocarriers as an emerging platform for cancer therapy" (Dan Peer, Jeffrey M. Karp, Seungpyo Hong et al., 2007), with 8,681 citations. Next come "Engineering precision nanoparticles for drug delivery" (7,854) and "Understanding biophysicochemical interactions at the nano–bio interface" (7,073).

Showing 50 of 100 papers. Every paper with more than 1,977 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Nanocarriers as an emerging platform for cancer therapy Dan Peer, Jeffrey M. Karp, Seungpyo Hong et al. · Nature Nanotechnology Dec 2007 8,681
2 Engineering precision nanoparticles for drug delivery Michael J. Mitchell, Margaret M. Billingsley, Rebecca M. Haley et al. · Nature Reviews Drug Discovery ReviewOpen access 4 Dec 2020 7,854
3 Understanding biophysicochemical interactions at the nano–bio interface André E. Nel, Lutz Mädler, Darrell Velegol et al. · Nature Materials 14 Jun 2009 7,073
4 Principles of nanoparticle design for overcoming biological barriers to drug delivery Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology Open access Sep 2015 6,967
5 Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications Sophie Laurent, Delphine Forge, Marc Port et al. · Chemical Reviews Review Jun 2008 6,788
6 Magnetic Nanoparticles: Synthesis, Protection, Functionalization, and Application An‐Hui Lu, Elena Lorena Salabaş, Ferdi Schüth · Angewandte Chemie International Edition 5 Feb 2007 6,770
7 Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications Ajay Kumar Gupta, Mona Sethi Gupta · Biomaterials 11 Dec 2004 6,765
8 Nano based drug delivery systems: recent developments and future prospects Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto et al. · Journal of Nanobiotechnology Open access 19 Sep 2018 6,726
9 Stimuli-responsive nanocarriers for drug delivery Simona Mura, Julien Nicolas, Patrick Couvreur · Nature Materials 23 Oct 2013 6,259
10 Applications of magnetic nanoparticles in biomedicine Quentin A. Pankhurst, Joan Connolly, Stephen K Jones et al. · Journal of Physics D Applied Physics 19 Jun 2003 5,871
11 Cancer nanomedicine: progress, challenges and opportunities Jinjun Shi, Philip W. Kantoff, Richard F. Wooster et al. · Nature reviews. Cancer ReviewOpen access 11 Nov 2016 5,834
12 Analysis of nanoparticle delivery to tumours Stefan Wilhelm, Anthony J. Tavares, Qin Dai et al. · Nature Reviews Materials ReviewOpen access 26 Apr 2016 5,120
13 Liposomal drug delivery systems: From concept to clinical applications Theresa M. Allen, Pieter R. Cullis · Advanced Drug Delivery Reviews Review Oct 2012 4,816
14 Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier Hirenkumar K. Makadia, Steven J. Siegel · Polymers Open access 26 Aug 2011 4,766
15 DLS and zeta potential – What they are and what they are not? Sourav Bhattacharjee · Journal of Controlled Release 12 Jun 2016 4,597
16 Drug Delivery Systems: Entering the Mainstream Theresa M. Allen, Pieter R. Cullis · Science 19 Mar 2004 4,545
17 PEGylation as a strategy for improving nanoparticle-based drug and gene delivery Jung Soo Suk, Qingguo Xu, Nam‐Ho Kim et al. · Advanced Drug Delivery Reviews ReviewOpen access 19 Oct 2015 4,511
18 Nanoparticle therapeutics: an emerging treatment modality for cancer Mark E. Davis, Zhuo Chen, Dong Moon Shin · Nature Reviews Drug Discovery Review Sep 2008 4,238
19 Hydrogels in pharmaceutical formulations Nicholas A. Peppas · European Journal of Pharmaceutics and Biopharmaceutics 3 Jul 2000 3,993
20 The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems Alexandre Albanese, Peter S. Tang, Warren C. W. Chan · Annual Review of Biomedical Engineering ReviewOpen access 21 Jun 2012 3,872
21 Drug delivery and nanoparticles: Applications and hazards de Jong · International Journal of Nanomedicine Open access Jun 2008 3,853
22 PLGA-based nanoparticles: An overview of biomedical applications Fabienne Danhier, Eduardo Ansorena, Joana M. Silva et al. · Journal of Controlled Release 4 Feb 2012 3,807
23 Biodegradable polymeric nanoparticles based drug delivery systems Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav · Colloids and Surfaces B Biointerfaces Open access 9 Sep 2009 3,716
24 Strategies in the design of nanoparticles for therapeutic applications Robby A. Petros, Joseph M. DeSimone · Nature Reviews Drug Discovery Review 9 Jul 2010 3,645
25 Liposome: classification, preparation, and applications Abolfazl Akbarzadeh, Rogaie Rezaei-Sadabady, Soodabeh Davaran et al. · Nanoscale Research Letters Open access 22 Feb 2013 3,634
26 PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs Zhuang Liu, Joshua Tucker Robinson, Xiaoming Sun et al. · Journal of the American Chemical Society Open access 29 Jul 2008 3,619
27 Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles D OWENSIII, Nicholas A. Peppas · International Journal of Pharmaceutics 22 Nov 2005 3,607
28 The golden age: gold nanoparticles for biomedicine Erik C. Dreaden, Alaaldin M. Alkilany, Xiaohua Huang et al. · Chemical Society Reviews ReviewOpen access 23 Nov 2011 3,550
29 Biodegradable polymeric nanoparticles as drug delivery devices Kumaresh S. Soppimath, Tejraj Malleshappa Aminabhavi, Anandrao R. Kulkarni et al. · Journal of Controlled Release 2001 3,537
30 Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives Katrin Knop, Richard Hoogenboom, Dagmar Fischer et al. · Angewandte Chemie International Edition 20 Jul 2010 3,525
31 Long-Circulating and Target-Specific Nanoparticles: Theory to Practice Seyed Moein Moghimi, Alan Christy Hunter, J. Clifford Murray · Pharmacological Reviews Jun 2001 3,514
32 Block copolymer micelles for drug delivery: design, characterization and biological significance Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki · Advanced Drug Delivery Reviews Review Mar 2001 3,504
33 Monodisperse MFe2O4 (M = Fe, Co, Mn) Nanoparticles Shouheng Sun, Hao Zeng, DAVID B. ROBINSON et al. · Journal of the American Chemical Society 10 Dec 2003 3,439
34 Biodegradable nanoparticles for drug and gene delivery to cells and tissue Jayanth Panyam, Vinod D. Labhasetwar · Advanced Drug Delivery Reviews Review Feb 2003 3,364
35 Impact of Nanotechnology on Drug Delivery Omid Cameron Farokhzad, Robert Langer · ACS Nano 27 Jan 2009 3,352
36 A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate Alfred G. Gilman · Proceedings of the National Academy of Sciences Open access Sep 1970 3,270
37 The dawning era of polymer therapeutics Ruth Duncan · Nature Reviews Drug Discovery Review May 2003 3,264
38 Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches Xifeng Zhang, Zhi-guo Liu, Wei Shen et al. · International Journal of Molecular Sciences Open access 13 Sep 2016 3,233
39 Delivering nanomedicine to solid tumors Rakesh K. Jain, Triantafyllos Stylianopoulos · Nature Reviews Clinical Oncology ReviewOpen access 14 Sep 2010 3,203
40 Nanoparticles in cancer therapy and diagnosis Irène Brigger, Catherine Dubernet, Patrick Couvreur · Advanced Drug Delivery Reviews Review Sep 2002 3,031
41 Thermo- and pH-responsive polymers in drug delivery☆ Dirk Schmaljohann · Advanced Drug Delivery Reviews 19 Oct 2006 3,023
42 Biomolecular coronas provide the biological identity of nanosized materials Marco P. Monopoli, Christoffer Åberg, Anna Laura Salvati et al. · Nature Nanotechnology Open access Dec 2012 2,970
43 Therapeutic Nanoparticles for Drug Delivery in Cancer Kwangjae Cho, Xu Wang, Shuming Nie et al. · Clinical Cancer Research Mar 2008 2,928
44 Biodegradable Long-Circulating Polymeric Nanospheres Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science 18 Mar 1994 2,919
45 Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Joanna Rejman, Volker Oberle, Inge S. Zuhorn et al. · Biochemical Journal Open access 2004 2,876
46 Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity Élodie Boisselier, Didier Astruc · Chemical Society Reviews Review 2009 2,843
47 Cellular uptake of nanoparticles: journey inside the cell Shahed Behzadi, Vahid Serpooshan, Wei Tao et al. · Chemical Society Reviews ReviewOpen access 2017 2,837
48 Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery Fangqiong Tang, Linlin Li, Dong Chen · Advanced Materials 29 Feb 2012 2,837
49 Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology Nicolas Bertrand, Jun Hua Wu, Xiaoyang Xu et al. · Advanced Drug Delivery Reviews ReviewOpen access 22 Nov 2013 2,819
50 Drug penetration in solid tumours Andrew Ivor Minchinton, Ian F. Tannock · Nature reviews. Cancer Review 24 Jul 2006 2,815

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.