Most cited papers in Natural product bioactivities and synthesis
What are the most cited papers in Natural product bioactivities and synthesis?
The most cited paper in Natural product bioactivities and synthesis is "Flavonoids: an overview" (Archana N. Panche, A D Diwan, Sheela Chandra, 2016), with 5,306 citations. Next come "Function and Activation of NF-kappaB in the Immune System" (4,729) and "Antimicrobial activity of flavonoids" (4,427).
Showing 50 of 100 papers. Every paper with more than 730 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Flavonoids: an overview Archana N. Panche, A D Diwan, Sheela Chandra · Journal of Nutritional Science | 2016 | 5,306 |
| 2 | Function and Activation of NF-kappaB in the Immune System Patrick A. Baeuerle, Thomas Henkel · Annual Review of Immunology | Apr 1994 | 4,729 |
| 3 | Antimicrobial activity of flavonoids T.P. Tim Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents | 20 Oct 2005 | 4,427 |
| 4 | Nuclear factor-κB in cancer development and progression Michael Karin · Nature | May 2006 | 3,552 |
| 5 | An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death Amer A. Beg, David Baltimore · Science | Nov 1996 | 3,082 |
| 6 | The NF- B Family of Transcription Factors and Its Regulation Andrea Oeckinghaus, Sankar Ghosh · Cold Spring Harbor Perspectives in Biology | 2 Sep 2009 | 2,889 |
| 7 | Anticancer potential of curcumin: preclinical and clinical studies. Bharat Bhushan Aggarwal, Anushree Jai Kumar, Alok Chandra Bharti · PubMed | May 2003 | 2,576 |
| 8 | Techniques for extraction and isolation of natural products: a comprehensive review Qingwen Zhang, Ligen Lin, Wen‐Cai Ye · Chinese Medicine | 17 Apr 2018 | 2,301 |
| 9 | Introduction to NF-κB: players, pathways, perspectives Thomas D. Gilmore · Oncogene | 30 Oct 2006 | 2,235 |
| 10 | IκB: a Specific Inhibitor of the NF-κB Transcription Factor Patrick A. Baeuerle, David Baltimore · Science | 28 Oct 1988 | 2,186 |
| 11 | Effect of Essential Oils on Pathogenic Bacteria Filomena Nazzaro, Florinda Fratianni, Laura De Martino et al. · Pharmaceuticals | 25 Nov 2013 | 2,170 |
| 12 | Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials Subash C. Gupta, Sridevi Patchva, Bharat Bhushan Aggarwal · The AAPS Journal | 9 Nov 2012 | 2,109 |
| 13 | IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation Frank Mercurio, Hengyi Zhu, Brion William Murray et al. · Science | 31 Oct 1997 | 2,049 |
| 14 | Plants as a source of anti-cancer agents Gordon M. L. Cragg, David J. Newman · Journal of Ethnopharmacology | 13 Jul 2005 | 2,046 |
| 15 | Crosstalk in NF-κB signaling pathways Andrea Oeckinghaus, Matthew S. Hayden, Sankar Ghosh · Nature Immunology | 19 Jul 2011 | 1,974 |
| 16 | The Essential Medicinal Chemistry of Curcumin Kathryn M. Nelson, Jayme L. Dahlin, Jonathan Bisson et al. · Journal of Medicinal Chemistry | 11 Jan 2017 | 1,950 |
| 17 | The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation Alexander Hoffmann, Andre Levchenko, Martin Scott et al. · Science | 7 Nov 2002 | 1,899 |
| 18 | Medicinal plants and antimicrobial activity José Luis Rı́os, M. Carmen Recio · Journal of Ethnopharmacology | 20 Jun 2005 | 1,881 |
| 19 | Ginseng pharmacology Anoja S. Attele, Ji An Wu, Chun‐Su Yuan · Biochemical Pharmacology | Dec 1999 | 1,869 |
| 20 | The biological action of saponins in animal systems: a review George Francis, Zohar Kerem, Harinder P. S. Makkar et al. · British Journal Of Nutrition | Dec 2002 | 1,721 |
| 21 | NF-κB, the first quarter-century: remarkable progress and outstanding questions Matthew S. Hayden, Sankar Ghosh · Genes & Development | Feb 2012 | 1,707 |
| 22 | The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β Min-Jean Yin, Yumi Yamamoto, Richard B. Gaynor · Nature | Nov 1998 | 1,594 |
| 23 | The flavonoids advances in research since 1986: MARGARET F. ROBERTS · Phytochemistry | Nov 1994 | 1,591 |
| 24 | Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer Yumi Yamamoto, Richard B. Gaynor · Journal of Clinical Investigation | 15 Jan 2001 | 1,587 |
| 25 | Nuclear factor-κB Bharat Bhushan Aggarwal · Cancer Cell | Sep 2004 | 1,574 |
| 26 | Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation Patrick Viatour, Marie‐Paule Merville, Vincent Bours et al. · Trends in Biochemical Sciences | 14 Dec 2004 | 1,517 |
| 27 | Biological activities and distribution of plant saponins S.G. Sparg, Marnie E. Light, J. van Staden · Journal of Ethnopharmacology | 27 Aug 2004 | 1,445 |
| 28 | Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB A S Baldwin · Journal of Clinical Investigation | Feb 2001 | 1,441 |
| 29 | Pharmacology of oleanolic acid and ursolic acid Jie Liu · Journal of Ethnopharmacology | Dec 1995 | 1,432 |
| 30 | Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Towia Aron Libermann, David Baltimore · Molecular and Cellular Biology | May 1990 | 1,384 |
| 31 | Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties Christine F Carson, Katherine A. Hammer, T. V. Riley · Clinical Microbiology Reviews | 2006 | 1,343 |
| 32 | New regulators of NF-κB in inflammation Sankar Ghosh, Matthew S. Hayden · Nature reviews. Immunology | 17 Oct 2008 | 1,332 |
| 33 | Medicinal plants in Mexico: healers' consensus and cultural importance Michael Heinrich, Anita Ankli, Barbara Frei et al. · Social Science & Medicine | Dec 1998 | 1,308 |
| 34 | Flavonoids: Old and new aspects of a class of natural therapeutic drugs Giulia Di Carlo, Nicola Mascolo, Angelo Antonio Izzo et al. · Life Sciences | Jun 1999 | 1,306 |
| 35 | Chromatographically homogeneous lecithin from egg phospholipids W. S. Singleton, M. S. Gray, M. L. Brown et al. · Journal of the American Oil Chemists Society | 1965 | 1,301 |
| 36 | 13C NMR Spectra of pentacyclic triterpenoids—a compilation and some salient features Shashi B. Mahato, Asish P. Kundu · Phytochemistry | Dec 1994 | 1,298 |
| 37 | The influence of natural products upon drug discovery (Antiquity to late 1999) David J. Newman, Gordon M. L. Cragg, Kenneth M. Snader · Natural Product Reports | 2000 | 1,296 |
| 38 | Phyto-oestrogens and Western Diseases Herman Adlercreutz, Witold Mazur · Annals of Medicine | 1997 | 1,286 |
| 39 | Structural and Chemical Biology of Terpenoid Cyclases David W. Christianson · Chemical Reviews | 25 Aug 2017 | 1,258 |
| 40 | Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Julie S Jurenka · PubMed | Jun 2009 | 1,220 |
| 41 | Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy Yong Lin, Ranxin Shi, Xia Wang et al. · Current Cancer Drug Targets | 30 Oct 2008 | 1,181 |
| 42 | Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets Bharat Bhushan Aggarwal, Bokyung Sung · Trends in Pharmacological Sciences | 27 Dec 2008 | 1,146 |
| 43 | The chemistry of tea flavonoids Douglas A. Balentine, Sheila A. Wiseman, Liesbeth C. M. Bouwens · Critical Reviews in Food Science and Nutrition | Dec 1997 | 1,133 |
| 44 | Plant terpenoid synthases: Molecular biology and phylogenetic analysis Jörg Bohlmann, Gilbert Meyer-Gauen, Rodney Croteau · Proceedings of the National Academy of Sciences | 14 Apr 1998 | 1,129 |
| 45 | Distribution and Biological Activities of the Flavonoid Luteolin Miguel López‐Lázaro · Mini-Reviews in Medicinal Chemistry | 31 Dec 2008 | 1,113 |
| 46 | Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB Thomas Henkel, Thomas Machleidt, Irit Alkalay et al. · Nature | Sep 1993 | 1,111 |
| 47 | The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal Michelle A. Kelliher, Stefan Grimm, Yasumasa Ishida et al. · Immunity | Mar 1998 | 1,104 |
| 48 | Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants Jörg Degenhardt, Tobias G. Köllner, Jonathan Gershenzon · Phytochemistry | 29 Sep 2009 | 1,102 |
| 49 | Signal transduction through NF-κB Michael J. May, Sankar Ghosh · Immunology Today | Feb 1998 | 1,098 |
| 50 | Mass spectrometry in the structural analysis of flavonoids Filip Cuyckens, Magda Claeys · Journal of Mass Spectrometry | 2004 | 1,085 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.