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Topic · Molecular Biology

Natural product bioactivities and synthesis

Natural product bioactivities and synthesis is a research topic within Molecular Biology. Science Explorer counts 48k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the biological activities, pharmacological properties, and potential therapeutic implications of triterpenoids and saponins, with a focus on their anti-cancer, anti-inflammatory, antioxidant, and antiviral properties. The research also delves into the use of saponins as adjuvants in vaccines and their effects on immune responses.

  • Triterpenoids
  • Saponins
  • Biological Activities
  • Cancer
  • Anti-inflammatory
  • Antioxidant
  • Pharmacological Properties
  • Adjuvants
  • Antiviral
  • Apoptosis
Research works
48k
fractional, since 1950
In the world top 10%
4.7k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+4%
the tick is no change
Largest producer
China
54% of the 10 largest, 2022-now
Natural product bioactivities and synthesis

Which countries lead Natural product bioactivities and synthesis research?

By volume, China and India publish the most (2.8k and 701 works in 2022-now).

By volume, 2022-now

  1. 1 China 2.8k works
  2. 2 India 701 works
  3. 3 South Korea 275 works
  4. 4 United States 256 works
  5. 5 Vietnam 207 works
  6. 6 Brazil 202 works
  7. 7 Russia 198 works
  8. 8 Türkiye 197 works
  9. 9 Japan 155 works
  10. 10 Iran 142 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 54.4%India: 13.7%South Korea: 5.4%United States: 5.0%6 others listed: 21.5%54%largest
China2,778 · 54.4%India701 · 13.7%South Korea275 · 5.4%United States256 · 5.0%6 others listed1,100 · 21.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead Natural product bioactivities and synthesis research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Natural product bioactivities and synthesis research, followed by Russian Academy of Sciences and Chinese Academy of Medical Sciences & Peking Union Medical College.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 148 works
  2. 2 Russian Academy of SciencesRussia 96 works
  3. 3 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 77 works
  4. 4 Vietnam Academy of Science and TechnologyVietnam 47 works
  5. 5 Shenyang Pharmaceutical UniversityChina 46 works
  6. 6 Chengdu University of Traditional Chinese MedicineChina 44 works
  7. 7 Chinese Academy of Agricultural SciencesChina 43 works
  8. 8 Heilongjiang University of Chinese MedicineChina 39 works
  9. 9 Shanghai University of Traditional Chinese MedicineChina 38 works
  10. 10 Council of Scientific and Industrial ResearchIndia 38 works

Who are the leading researchers in Natural product bioactivities and synthesis?

The most-cited researchers publishing on Natural product bioactivities and synthesis include Shizuo Akira, Jun Wang and Michael Karin.

  1. 1 Shizuo Akira Japan 342k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Michael Karin United States 276k citations
  4. 4 Amirhossein Sahebkar Iran 258k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Natural product bioactivities and synthesis?

The most cited paper in Natural product bioactivities and synthesis is "Flavonoids: an overview" (Archana N. Panche, A D Diwan, Sheela Chandra, 2016), with 5,306 citations. Next come "Function and Activation of NF-kappaB in the Immune System" (4,729) and "Antimicrobial activity of flavonoids" (4,427).

Most cited papers
#PaperReleasedCitations
1 Flavonoids: an overview Archana N. Panche, A D Diwan, Sheela Chandra · Journal of Nutritional Science Open access 2016 5,306
2 Function and Activation of NF-kappaB in the Immune System Patrick A. Baeuerle, Thomas Henkel · Annual Review of Immunology Apr 1994 4,729
3 Antimicrobial activity of flavonoids T.P. Tim Cushnie, Andrew J. Lamb · International Journal of Antimicrobial Agents Open access 20 Oct 2005 4,427
4 Nuclear factor-κB in cancer development and progression Michael Karin · Nature May 2006 3,552
5 An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death Amer A. Beg, David Baltimore · Science Nov 1996 3,082
All 100 most cited papers, with filters and sorting

Where is Natural product bioactivities and synthesis research done?

The largest centres of Natural product bioactivities and synthesis research in 2022-now are Beijing (China), Guangzhou (China), Shanghai (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Yanji, Tbilisi and Ufa.

Largest cities, 2022-now

  1. 1 BeijingChina 379 works
  2. 2 GuangzhouChina 143 works
  3. 3 ShanghaiChina 124 works
  4. 4 NanjingChina 111 works
  5. 5 KunmingChina 106 works
  6. 6 HanoiVietnam 90 works
  7. 7 ChengduChina 88 works
  8. 8 HarbinChina 88 works
  9. 9 ShenyangChina 83 works
  10. 10 HangzhouChina 82 works

Where it is the local speciality

  1. YanjiCN · 23.0 works28×
  2. TbilisiGE · 36.6 works12×
  3. UfaRU · 29.7 works11×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Natural product bioactivities and synthesis than the world average.

See Natural product bioactivities and synthesis on the map

Where is the best place to study Natural product bioactivities and synthesis?

Among universities, judged by research, Chengdu University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine and King Saud University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 18.59%fractional works in this field (log) →share of work in the world top 10% →Chengdu University o…Shanghai University …Guangzhou University…King Saud University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Chengdu University of Traditional Chinese MedicineChina 83.030.4%27.2×44 +67.8%
2Shanghai University of Traditional Chinese MedicineChina 59.716.5%21.9×38 +9.3%
3King Saud UniversitySaudi Arabia 59.013.4%4.5×28 +52.4%
4Guangzhou University of Chinese MedicineChina 58.916.5%19.6×30 +24.6%
5Northeast Forestry UniversityChina 57.320.3%8.6×16 +80.8%
6Northeast Agricultural UniversityChina 57.329.3%5.8×10 +75.8%
7Heilongjiang University of Chinese MedicineChina 56.913.4%70.5×40 +106.0%
8Zunyi Medical UniversityChina 55.116.8%17.9×19 +54.0%
9Victor Babeș University of Medicine and Pharmacy TimișoaraRomania 54.520.6%18.0×10 +44.7%
10Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 54.28.7%11.5×77 -15.9%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Natural product bioactivities and synthesis, country by country

Is Natural product bioactivities and synthesis research growing?

Output in 2022-2025 was 4% higher than in 2018-2021, peaking in 2012. The fastest-growing topics are Natural product bioactivities and synthesis.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Natural product bioactivities and synthesis as a percentage of every work published that year, 0.032% in 2024.

still counting0.025%0.050%0.075%Natural product bioactivities and synthesis0.029% in 202519801990200020102020

Fractional works of Natural product bioactivities and synthesis over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Natural product bioactivities and synthesis10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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