Most cited papers in Neurological diseases and metabolism
What are the most cited papers in Neurological diseases and metabolism?
The most cited paper in Neurological diseases and metabolism is "Staging of brain pathology related to sporadic Parkinson’s disease" (Heiko Braak, Kelly Del Tredici, Udo Rüb et al., 2002), with 10,980 citations. Next come "α-Synuclein in Lewy bodies" (8,529) and "Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease" (8,336).
Showing 50 of 100 papers. Every paper with more than 1,049 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Staging of brain pathology related to sporadic Parkinson’s disease Heiko Braak, Kelly Del Tredici, Udo Rüb et al. · Neurobiology of Aging | 28 Dec 2002 | 10,980 |
| 2 | α-Synuclein in Lewy bodies Maria Grazia Spillantini, Marie Luise Schmidt, Virginia M.‐Y. Lee et al. · Nature | 28 Aug 1997 | 8,529 |
| 3 | Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease Mihael H. Polymeropoulos, Christian N. Lavedan, Elisabeth Leroy et al. · Science | 27 Jun 1997 | 8,336 |
| 4 | MDS clinical diagnostic criteria for Parkinson's disease Ronald B. Postuma, Daniela Berg, Matthew Stern et al. · Movement Disorders | Oct 2015 | 7,758 |
| 5 | Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science | 5 Oct 2006 | 6,756 |
| 6 | El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis Benjamin Rix Brooks, Robert G. Miller, Michael Swash et al. · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders | 2000 | 5,487 |
| 7 | Prions Stanley Ben Prusiner · Proceedings of the National Academy of Sciences | 10 Nov 1998 | 5,428 |
| 8 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD Alan Edward Renton et al. · Neuron | 22 Sep 2011 | 4,545 |
| 9 | Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu et al. · Science | 17 Jun 1994 | 4,179 |
| 10 | Epidemiology of Parkinson's disease Lonneke ML de Lau, Monique M.B. Breteler · The Lancet Neurology | 20 May 2006 | 4,142 |
| 11 | Chronic systemic pesticide exposure reproduces features of Parkinson's disease Ranjita S. Betarbet, Todd Sherer, Gillian M. MacKenzie et al. · Nature Neuroscience | Dec 2000 | 3,729 |
| 12 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. William R G Gibb, Andrew John Lees · Journal of Neurology Neurosurgery & Psychiatry | Jun 1988 | 3,523 |
| 13 | Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 Enza Maria Valente et al. · Science | 19 Apr 2004 | 3,521 |
| 14 | The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders Berislav V. Zloković · Neuron | 2008 | 3,300 |
| 15 | Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology Alexander A. Zimprich et al. · Neuron | Nov 2004 | 3,086 |
| 16 | Clinical diagnostic criteria for dementia associated with Parkinson's disease Murat Emre et al. · Movement Disorders | 31 May 2007 | 3,081 |
| 17 | Diagnostic Criteria for Parkinson Disease Douglas J. Gelb, Eugene Oliver, Sid Gilman · Archives of Neurology | 1999 | 2,859 |
| 18 | Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism Vincenzo Bonifati, Patrizia Rizzu, Marijke J. van Baren et al. · Science | 9 Jan 2003 | 2,807 |
| 19 | The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia Juan Jose Zarranz, Javier Alegre, Juan Carlos Gómez‐Esteban et al. · Annals of Neurology | 30 Dec 2003 | 2,780 |
| 20 | Stages in the development of Parkinson’s disease-related pathology Heiko Braak, Estifanos Ghebremedhin, Udo Rüb et al. · Cell and Tissue Research | 23 Aug 2004 | 2,732 |
| 21 | A new variant of Creutzfeldt-Jakob disease in the UK Robert G. Will, James W. Ironside, Martin Zeidler et al. · The Lancet | Apr 1996 | 2,714 |
| 22 | Oxidative stress and neurodegeneration: where are we now? Barry B. Halliwell · Journal of Neurochemistry | Jun 2006 | 2,617 |
| 23 | Epidemiology of Parkinson’s disease Ole‐Bjørn Tysnes, Anette Margrethe Storstein · Journal of Neural Transmission | Feb 2017 | 2,472 |
| 24 | Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease Coro Paisán-Ruı́z et al. · Neuron | Nov 2004 | 2,463 |
| 25 | Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. K M Pan, M. A. Baldwin, Jack T Nguyen et al. · Proceedings of the National Academy of Sciences | Dec 1993 | 2,280 |
| 26 | Structure of the cross-β spine of amyloid-like fibrils Rebecca A. Nelson, Michael R. Sawaya, Melinda Balbirnie et al. · Nature | Jun 2005 | 2,229 |
| 27 | The prevalence of Parkinson's disease: A systematic review and meta‐analysis Tamara M. Pringsheim, Nathalie Jetté, Alexandra D. Frolkis et al. · Movement Disorders | 28 Jun 2014 | 2,214 |
| 28 | Amyotrophic Lateral Sclerosis Robert H. Brown, Ammar Al‐Chalabi · New England Journal of Medicine | 12 Jul 2017 | 2,195 |
| 29 | The Emerging Evidence of the Parkinson Pandemic Earl Ray Dorsey, Todd Sherer, Michael S. Okun et al. · Journal of Parkinson s Disease | 18 Dec 2018 | 2,057 |
| 30 | Molecular Biology of Prion Diseases Stanley Ben Prusiner · Science | 14 Jun 1991 | 1,992 |
| 31 | Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent M. E. Bruce, Robert G. Will, James W. Ironside et al. · Nature | Oct 1997 | 1,991 |
| 32 | Genome-wide association study reveals genetic risk underlying Parkinson's disease Javier Simón‐Sánchez et al. · Nature Genetics | 15 Nov 2009 | 1,981 |
| 33 | Challenges in the diagnosis of Parkinson's disease EDUARDO S. TOLOSA, Alícia Garrido, Sonja W. Scholz et al. · The Lancet Neurology | 21 Apr 2021 | 1,878 |
| 34 | Oxidative stress in neurodegeneration: cause or consequence? Julie Kay Andersen · Nature Medicine | Jul 2004 | 1,876 |
| 35 | The role of iron in brain ageing and neurodegenerative disorders Roberta J. Ward, Fabio Andrea Zucca, Jeff H. Duyn et al. · The Lancet Neurology | 15 Sep 2014 | 1,864 |
| 36 | Amyotrophic Lateral Sclerosis Lewis P. Rowland, Neil A. Shneider · New England Journal of Medicine | 31 May 2001 | 1,840 |
| 37 | Iron, brain ageing and neurodegenerative disorders Luigi Zecca, Moussa B. H. Youdim, Peter Franz Riederer et al. · Nature reviews. Neuroscience | 20 Oct 2004 | 1,836 |
| 38 | Hallmarks of neurodegenerative diseases David M. Wilson, Mark Cookson, Ludo Van Den Bosch et al. · Cell | Feb 2023 | 1,784 |
| 39 | Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD John Collinge, Katie C. L. Sidle, Julie Meads et al. · Nature | Oct 1996 | 1,740 |
| 40 | Establishment and Dysfunction of the Blood-Brain Barrier Zhen Zhao, Amy R. Nelson, Christer Betsholtz et al. · Cell | Nov 2015 | 1,719 |
| 41 | Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen Heiko Braak, U. R�b, W. P. Gai et al. · Journal of Neural Transmission | May 2003 | 1,716 |
| 42 | Self-propagation of pathogenic protein aggregates in neurodegenerative diseases Mathias Jucker, Lary C. Walker · Nature | 3 Sep 2013 | 1,704 |
| 43 | Pathology of Neurodegenerative Diseases Brittany N. Dugger, Dennis W. Dickson · Cold Spring Harbor Perspectives in Biology | 6 Jan 2017 | 1,673 |
| 44 | Molecular Pathways of Neurodegeneration in Parkinson's Disease Ted M. Dawson, Valina L. Dawson · Science | 30 Oct 2003 | 1,671 |
| 45 | Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein Hansruedi Büeler, Marek Fischer, Yolande Lang et al. · Nature | Apr 1992 | 1,666 |
| 46 | MODELS OF AMYLOID SEEDING IN ALZHEIMER'S DISEASE AND SCRAPIE: Mechanistic Truths and Physiological Consequences of the Time-Dependent Solubility of Amyloid Proteins James D. Harper, Peter T. Lansbury · Annual Review of Biochemistry | Jun 1997 | 1,661 |
| 47 | P ROTOFIBRILS , P ORES , F IBRILS, AND N EURODEGENERATION : Separating the Responsible Protein Aggregates from The Innocent Bystanders Byron W. Caughey, Peter T. Lansbury · Annual Review of Neuroscience | Mar 2003 | 1,656 |
| 48 | Role of neuroinflammation in neurodegeneration development Weifeng Zhang, Dan Xiao, Qinwen Mao et al. · Signal Transduction and Targeted Therapy | 11 Jul 2023 | 1,625 |
| 49 | The ubiquitin pathway in Parkinson's disease Elisabeth Leroy, Rebecca L. Boyer, Georg W. J. Auburger et al. · Nature | Oct 1998 | 1,582 |
| 50 | State of play in amyotrophic lateral sclerosis genetics Alan Edward Renton, Adriano Chiò, Bryan J. Traynor · Nature Neuroscience | 26 Dec 2013 | 1,576 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.