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Topic · Neurology

Neurological diseases and metabolism

Neurological diseases and metabolism is a research topic within Neurology. Science Explorer counts 16k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on neurodegenerative disorders associated with brain iron accumulation, particularly emphasizing the genetic mutations in genes such as Pantothenate Kinase (PANK2), Coenzyme A biosynthesis, and Phospholipase A2 (PLA2G6). The research also explores the clinical, radiographic, and neuroimaging features of these disorders.

  • Neurodegeneration
  • Brain Iron Accumulation
  • Pantothenate Kinase
  • Coenzyme A
  • Genetic Mutations
  • Phospholipase A2
  • Ferritin
  • Neuroimaging
  • Mitochondrial Dysfunction
  • Parkinsonism
Research works
16k
fractional, since 1950
In the world top 10%
1.6k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-2%
the tick is no change
Largest producer
United States
30% of the 10 largest, 2022-now
Neurological diseases and metabolism

Which countries lead Neurological diseases and metabolism research?

By volume, the United States and China publish the most (472 and 302 works in 2022-now).

By volume, 2022-now

  1. 1 United States 472 works
  2. 2 China 302 works
  3. 3 India 154 works
  4. 4 United Kingdom 126 works
  5. 5 Italy 111 works
  6. 6 Japan 110 works
  7. 7 Germany 95 works
  8. 8 France 95 works
  9. 9 Brazil 67 works
  10. 10 Canada 57 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 29.7%China: 19.0%India: 9.7%United Kingdom: 8.0%6 others listed: 33.6%30%largest
United States472 · 29.7%China302 · 19.0%India154 · 9.7%United Kingdom126 · 8.0%6 others listed534 · 33.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Neurological diseases and metabolism research?

By volume in 2022-now, University College London publishes the most Neurological diseases and metabolism research, followed by Harvard University and National Institutes of Health.

Who are the leading researchers in Neurological diseases and metabolism?

The most-cited researchers publishing on Neurological diseases and metabolism include George Davey Smith, Mark J. Daly and Jun Wang.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Mark J. Daly United States 403k citations
  3. 3 Jun Wang China 340k citations
  4. 4 John P. A. Ioannidis United States 317k citations
  5. 5 Richard A. Gibbs United States 292k citations
  6. 6 John Q. Trojanowski United States 286k citations
  7. 7 Luigi Ferrucci United States 281k citations
  8. 8 Cornelia M. van Duijn Netherlands 250k citations
  9. 9 Derrick Bennett United Kingdom 248k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Neurological diseases and metabolism?

The most cited paper in Neurological diseases and metabolism is "Staging of brain pathology related to sporadic Parkinson’s disease" (Heiko Braak, Kelly Del Tredici, Udo Rüb et al., 2002), with 10,980 citations. Next come "α-Synuclein in Lewy bodies" (8,529) and "Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease" (8,336).

Most cited papers
#PaperReleasedCitations
1 Staging of brain pathology related to sporadic Parkinson’s disease Heiko Braak, Kelly Del Tredici, Udo Rüb et al. · Neurobiology of Aging 28 Dec 2002 10,980
2 α-Synuclein in Lewy bodies Maria Grazia Spillantini, Marie Luise Schmidt, Virginia M.‐Y. Lee et al. · Nature 28 Aug 1997 8,529
3 Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease Mihael H. Polymeropoulos, Christian N. Lavedan, Elisabeth Leroy et al. · Science 27 Jun 1997 8,336
4 MDS clinical diagnostic criteria for Parkinson's disease Ronald B. Postuma, Daniela Berg, Matthew Stern et al. · Movement Disorders Oct 2015 7,758
5 Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science 5 Oct 2006 6,756
All 100 most cited papers, with filters and sorting

Where is Neurological diseases and metabolism research done?

The largest centres of Neurological diseases and metabolism research in 2022-now are London (United Kingdom), Beijing (China), Paris (France) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Milan.

Largest cities, 2022-now

  1. 1 LondonUnited Kingdom 53 works
  2. 2 BeijingChina 51 works
  3. 3 ParisFrance 38 works
  4. 4 TokyoJapan 27 works
  5. 5 MilanItaly 23 works
  6. 6 ShanghaiChina 20 works
  7. 7 HangzhouChina 20 works
  8. 8 SeoulSouth Korea 20 works
  9. 9 New YorkUnited States 20 works
  10. 10 RomeItaly 19 works

Where it is the local speciality

  1. MilanIT · 22.8 works3.6×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Neurological diseases and metabolism than the world average.

See Neurological diseases and metabolism on the map

Where is the best place to study Neurological diseases and metabolism?

Among universities, judged by research, University College London, Harvard University and Case Western Reserve University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 10.91%fractional works in this field (log) →share of work in the world top 10% →University College L…Case Western Reserve…Harvard UniversityUniversity of Toronto
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University College LondonUnited Kingdom 91.017.8%9.3×29 -16.1%
2Harvard UniversityUnited States 77.315.2%3.0×18 +22.8%
3Case Western Reserve UniversityUnited States 50.516.4%7.7×9 -0.5%
4University of TorontoCanada 47.711.5%2.9×11 -3.9%
5University of PennsylvaniaUnited States 47.411.3%4.2×8 +1.1%
6Capital Medical UniversityChina 39.58.0%5.9×12 +21.3%
7Zhejiang UniversityChina 38.310.0%1.9×10 +24.4%
8McGill UniversityCanada 37.210.1%4.4×8 -39.1%
9Central South UniversityChina 34.37.7%3.1×11 +10.9%
10All India Institute of Medical SciencesIndia 28.81.1%6.3×13 +93.5%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Neurological diseases and metabolism, country by country

Is Neurological diseases and metabolism research growing?

Output in 2022-2025 was 2% lower than in 2018-2021, peaking in 2021.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Neurological diseases and metabolism as a percentage of every work published that year, 0.0084% in 2024.

still counting0.010%0.020%0.030%Neurological diseases and metabolism0.0086% in 202519801990200020102020

Fractional works of Neurological diseases and metabolism over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Neurological diseases and metabolism10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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