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Topic · Neurology

Vagus Nerve Stimulation Research

Vagus Nerve Stimulation Research is a research topic within Neurology. Science Explorer counts 11k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the neuro-immune modulation achieved through vagus nerve stimulation, particularly its role in regulating inflammation, cholinergic antiinflammatory pathway, neural reflexes, and immunomodulation. The research covers the anti-inflammatory effects of vagus nerve stimulation, its application in epilepsy treatment, and its potential as a therapy for heart failure.

  • Vagus Nerve Stimulation
  • Cholinergic Antiinflammatory Pathway
  • Inflammation Regulation
  • Neural Reflexes
  • Immunomodulation
  • Neuro-Immune Communication
  • Anti-inflammatory Effects
  • Cholinergic Control
  • Epilepsy Treatment
  • Heart Failure Therapy
Research works
11k
fractional, since 1950
In the world top 10%
1.1k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+50%
the tick is no change
Largest producer
United States
38% of the 10 largest, 2022-now
Vagus Nerve Stimulation Research

Which countries lead Vagus Nerve Stimulation Research research?

By volume, the United States and China publish the most (1k and 845 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1k works
  2. 2 China 845 works
  3. 3 Germany 162 works
  4. 4 United Kingdom 130 works
  5. 5 Italy 115 works
  6. 6 Japan 113 works
  7. 7 India 102 works
  8. 8 Canada 81 works
  9. 9 Brazil 76 works
  10. 10 France 73 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 37.6%China: 31.1%Germany: 5.9%United Kingdom: 4.8%6 others listed: 20.6%38%largest
United States1,024 · 37.6%China845 · 31.1%Germany162 · 5.9%United Kingdom130 · 4.8%6 others listed560 · 20.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Vagus Nerve Stimulation Research research?

By volume in 2022-now, Harvard University publishes the most Vagus Nerve Stimulation Research research, followed by Capital Medical University and Northwell Health.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 47 works
  2. 2 Capital Medical UniversityChina 31 works
  3. 3 Northwell HealthUnited States 27 works
  4. 4 Mayo ClinicUnited States 24 works
  5. 5 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 22 works
  6. 6 University of TorontoCanada 21 works
  7. 7 Shanghai Jiao Tong UniversityChina 20 works
  8. 8 Sun Yat-sen UniversityChina 18 works
  9. 9 University of California, Los AngelesUnited States 18 works
  10. 10 Nanjing Medical UniversityChina 18 works

Who are the leading researchers in Vagus Nerve Stimulation Research?

The most-cited researchers publishing on Vagus Nerve Stimulation Research include Jost Bruno Jonas, Mika Kivimäki and Gregory Y.H. Lip.

  1. 1 Jost Bruno Jonas Germany 350k citations
  2. 2 Mika Kivimäki United Kingdom 318k citations
  3. 3 Gregory Y.H. Lip United Kingdom 311k citations
  4. 4 Róbert Langer United States 303k citations
  5. 5 Jean‐Louis Vincent Belgium 262k citations
  6. 6 Piotr P. Ponikowski Poland 253k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Vagus Nerve Stimulation Research?

The most cited paper in Vagus Nerve Stimulation Research is "Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin" (Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al., 2000), with 4,235 citations. Next come "Stress and the Individual" (4,058) and "The inflammatory reflex" (3,734).

Most cited papers
#PaperReleasedCitations
1 Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al. · Nature May 2000 4,235
2 Stress and the Individual Bruce S. McEwen · Archives of Internal Medicine 27 Sep 1993 4,058
3 The inflammatory reflex Kevin J. Tracey · Nature Dec 2002 3,734
4 The Classical Complement Cascade Mediates CNS Synapse Elimination Beth A. Stevens, Nicola J. Allen, Luis E Vazquez et al. · Cell Open access Dec 2007 3,414
5 Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation Hong Tian Wang, Man Yu, Mahendar Ochani et al. · Nature 22 Dec 2002 3,242
All 100 most cited papers, with filters and sorting

Where is Vagus Nerve Stimulation Research research done?

The largest centres of Vagus Nerve Stimulation Research research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and London (United Kingdom). Among places with at least 20 works in it, it is an unusually large share of all research in Durham and Cleveland.

Largest cities, 2022-now

  1. 1 BeijingChina 141 works
  2. 2 ShanghaiChina 71 works
  3. 3 GuangzhouChina 53 works
  4. 4 LondonUnited Kingdom 47 works
  5. 5 WuhanChina 44 works
  6. 6 New YorkUnited States 44 works
  7. 7 NanjingChina 39 works
  8. 8 BostonUnited States 37 works
  9. 9 ChengduChina 36 works
  10. 10 SeoulSouth Korea 36 works

Where it is the local speciality

  1. DurhamUS · 20.6 works4.9×
  2. ClevelandUS · 22.0 works4.4×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Vagus Nerve Stimulation Research than the world average.

See Vagus Nerve Stimulation Research on the map

Where is the best place to study Vagus Nerve Stimulation Research?

Among universities, judged by research, Harvard University, Chinese Academy of Medical Sciences & Peking Union Medical College and University of Oklahoma score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 17.3%fractional works in this field (log) →share of work in the world top 10% →Chinese Academy of M…University of OklahomaHarvard UniversityUniversity of Toronto
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 91.318.8%4.7×47 +32.3%
2Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 73.619.8%6.7×22 +75.5%
3University of OklahomaUnited States 65.719.6%9.6×11 +133.8%
4University of TorontoCanada 65.612.9%3.3×21 +16.7%
5Huazhong University of Science and TechnologyChina 65.524.2%2.6×15 +146.4%
6Medical University of ViennaAustria 63.321.3%8.7×9 +90.0%
7University of California, Los AngelesUnited States 63.116.1%5.0×18 +82.6%
8Capital Medical UniversityChina 62.111.8%9.2×31 +56.8%
9Duke UniversityUnited States 61.211.7%6.3×16 +114.9%
10Shanghai University of Traditional Chinese MedicineChina 57.716.8%17.0×14 +118.5%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Vagus Nerve Stimulation Research, country by country

Is Vagus Nerve Stimulation Research research growing?

Output in 2022-2025 was 50% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Vagus Nerve Stimulation Research.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Vagus Nerve Stimulation Research as a percentage of every work published that year, 0.012% in 2024.

still counting0.010%0.020%Vagus Nerve Stimulation Research0.017% in 202519801990200020102020

Fractional works of Vagus Nerve Stimulation Research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Vagus Nerve Stimulation Research10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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