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Most cited papers in Nitric Oxide and Endothelin Effects

Nitric Oxide and Endothelin Effects

What are the most cited papers in Nitric Oxide and Endothelin Effects?

The most cited paper in Nitric Oxide and Endothelin Effects is "Nitric oxide: physiology, pathophysiology, and pharmacology." (Salvador Moncada, Richard M. J. Palmer, E.A. Higgs, 1991), with 15,612 citations. Next come "Superoxide Dismutase" (12,906) and "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine" (12,123).

Showing 50 of 99 papers. Every paper with more than 1,833 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Nitric oxide: physiology, pathophysiology, and pharmacology. Salvador Moncada, Richard M. J. Palmer, E.A. Higgs · Pharmacological Reviews Jun 1991 15,612
2 Superoxide Dismutase Joe M. McCord, Irwin Fridovich · Journal of Biological Chemistry Open access Nov 1969 12,906
3 The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Robert F. Furchgott, John V. Zawadzki · Nature Nov 1980 12,123
4 A novel potent vasoconstrictor peptide produced by vascular endothelial cells Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature Open access Mar 1988 10,827
5 Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor Richard M. J. Palmer, Anthony G. Ferrige, Salvador Moncada · Nature Jun 1987 10,799
6 Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Joseph S. Beckman, ThomasJ Beckman, Jake Y. Chen et al. · Proceedings of the National Academy of Sciences Open access Feb 1990 7,073
7 The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology Karen Bedard, Karl‐Heinz Krause · Physiological Reviews ReviewOpen access 2007 7,002
8 The L-Arginine-Nitric Oxide Pathway Franklin H. Epstein, Salvador Moncada, Annie Higgs · New England Journal of Medicine 30 Dec 1993 6,737
9 Nitric Oxide and Peroxynitrite in Health and Disease Pál Pacher, Joseph S. Beckman, Lucas Liaudet · Physiological Reviews ReviewOpen access 2007 6,382
10 A modified uronic acid carbazole reaction Thomas Bitter, H. M. Muir · Analytical Biochemistry Oct 1962 6,285
11 Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Joseph S. Beckman, Willem Hendrik Koppenol · American Journal of Physiology-Cell Physiology Nov 1996 5,539
12 Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. L J Ignarro, Georgette M. Buga, Keith S. Wood et al. · Proceedings of the National Academy of Sciences Open access Dec 1987 5,093
13 Vascular endothelial cells synthesize nitric oxide from L-arginine Richard M. J. Palmer, D. Ashton, Salvador Moncada · Nature Jun 1988 4,797
14 Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril Pamela J. Fraker, John C. Speck · Biochemical and Biophysical Research Communications Feb 1978 4,596
15 Nitric oxide synthases: regulation and function Ulrich Förstermann, William C. Sessa · European Heart Journal Open access Sep 2011 4,393
16 Nitric oxide as a secretory product of mammalian cells Carl Nathan · The FASEB Journal Sep 1992 4,392
17 Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature Apr 2000 4,302
18 NITRIC OXIDE AND MACROPHAGE FUNCTION John D. MacMicking, Q W Xie, Carl Nathan · Annual Review of Immunology Review Apr 1997 4,227
19 A Rapid, Simple Spectrophotometric Method for Simultaneous Detection of Nitrate and Nitrite Katrina M. Miranda, Michael Graham Espey, David A. Wink · Nitric Oxide Feb 2001 3,899
20 Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress Hua “Linda” Cai, David Glenn Harrison · Circulation Research Open access 10 Nov 2000 3,832
21 Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation Stefanie Dimmeler, Ingrid Fleming, Beate Fißlthaler et al. · Nature Jun 1999 3,605
22 Nitric oxide synthases: structure, function and inhibition Wendy K. ALDERTON, Chris E. Cooper, Richard G. Knowles · Biochemical Journal Open access Aug 2001 3,544
23 Nitric oxide and the immune response Christian Bogdan · Nature Immunology Oct 2001 3,458
24 Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk Jonathan Michael Hill, Gloria Zalos, Julian Halcox et al. · New England Journal of Medicine 12 Feb 2003 3,434
25 The preparation and properties of two new chromogenic substrates of trypsin Bernard F. Erlanger, Nicholas Kokowsky, William Cohen · Archives of Biochemistry and Biophysics Nov 1961 3,383
26 Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. David S. Bredt, Solomon H. Snyder · Proceedings of the National Academy of Sciences Open access 1990 3,308
27 NOX enzymes and the biology of reactive oxygen J. David Lambeth · Nature reviews. Immunology Review Mar 2004 3,126
28 Nitric oxide: an endogenous modulator of leukocyte adhesion. Paul Kubes, Motohisa Suzuki, D. Neil Granger · Proceedings of the National Academy of Sciences Open access Jun 1991 3,055
29 Localization of nitric oxide synthase indicating a neural role for nitric oxide David S. Bredt, Paul M. Hwang, Solomon H. Snyder · Nature 25 Oct 1990 3,012
30 Nitric oxide synthases: Roles, tolls, and controls Carl Nathan, Q W Xie · Cell Sep 1994 2,947
31 Reactive oxygen species in cell signaling Victor John Thannickal, Barry L. Fanburg · American Journal of Physiology-Lung Cellular and Molecular Physiology Dec 2000 2,932
32 NAD(P)H Oxidase Kathy K. Griendling, Dan C. Sorescu, Masuko Ushio‐Fukai · Circulation Research Open access 17 Mar 2000 2,891
33 Arginine metabolism: nitric oxide and beyond Guoyao Wu, Sidney M. Morris · Biochemical Journal Open access 15 Nov 1998 2,830
34 Flow-mediated endothelial mechanotransduction Peter Francis Davies · Physiological Reviews Open access Jul 1995 2,810
35 Nitric oxide synthases in mammals Richard G. Knowles, Salvador Moncada · Biochemical Journal Open access Mar 1994 2,772
36 The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies Celia Andrés, José Manuel Pérez de la Lastra, Francisco J. Plou et al. · International Journal of Molecular Sciences Open access 28 Apr 2021 2,768
37 Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Kathy K. Griendling, C A Minieri, Jeremy D. Ollerenshaw et al. · Circulation Research Open access Jun 1994 2,757
38 Biochemistry of Nitric Oxide and Its Redox-Activated Forms Jonathan S. Stamler, David J. Singel, Joseph Loscalzo · Science 18 Dec 1992 2,754
39 The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics Jon O. Lundberg, Eddie Weitzberg, Mark T. Gladwin · Nature Reviews Drug Discovery Review 2 Jan 2008 2,738
40 Bosentan Therapy for Pulmonary Arterial Hypertension Lewis J. Rubin, David B. Badesch, Robyn J. Barst et al. · New England Journal of Medicine Open access 21 Mar 2002 2,736
41 Regulation of endothelium-derived nitric oxide production by the protein kinase Akt David J. Fulton, Jean‐Philippe Gratton, Timothy J. D. McCabe et al. · Nature Open access 10 Jun 1999 2,624
42 Cloning and expression of a cDNA encoding an endothelin receptor Hiroshi Arai, Seiji Hori, Ichiro Aramori et al. · Nature Dec 1990 2,597
43 Prognostic Impact of Coronary Vasodilator Dysfunction on Adverse Long-Term Outcome of Coronary Heart Disease Volker Schächinger, Martina B. Britten, Andreas Michael Zeiher · Circulation 25 Apr 2000 2,594
44 Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain John Garthwaite, Sarah L. Charles, Russ Chess‐Williams · Nature Nov 1988 2,568
45 Glial and neuronal control of brain blood flow David Attwell, Alastair Mitchell Buchan, Serge Charpak et al. · Nature Open access 9 Nov 2010 2,557
46 The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Akiko Inoue, Masashi Yanagisawa, Sadao Kimura et al. · Proceedings of the National Academy of Sciences Open access Apr 1989 2,536
47 Requirement for Generation of H 2 O 2 for Platelet-Derived Growth Factor Signal Transduction Maitrayee Sundaresan, Zu-Xi Yu, Victor J. Ferrans et al. · Science 13 Oct 1995 2,532
48 Reconciling the chemistry and biology of reactive oxygen species Christine C. Winterbourn · Nature Chemical Biology 17 Apr 2008 2,512
49 Peroxynitrite oxidation of sulfhydryls. Rafael Radí, Joseph S. Beckman, Ken Bush et al. · Journal of Biological Chemistry Open access Mar 1991 2,493
50 Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. Sanjay Rajagopalan, Stephan Dominik Kurz, Thomas Münzel et al. · Journal of Clinical Investigation Open access 15 Apr 1996 2,463

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.