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Most cited papers in Pharmaceutical and Antibiotic Environmental Impacts

Pharmaceutical and Antibiotic Environmental Impacts

What are the most cited papers in Pharmaceutical and Antibiotic Environmental Impacts?

The most cited paper in Pharmaceutical and Antibiotic Environmental Impacts is "Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance" (Dana W. Kolpin, Edward T. Furlong, Michael T. Meyer et al., 2002), with 7,962 citations. Next come "Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test" (7,423) and "Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances" (6,274).

Showing 50 of 100 papers. Every paper with more than 1,554 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance Dana W. Kolpin, Edward T. Furlong, Michael T. Meyer et al. · Environmental Science & Technology Mar 2002 7,962
2 Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test Bruce N. Ames, Joyce McCann, Edith F. Yamasaki · Mutation Research/Environmental Mutagenesis and Related Subjects Dec 1975 7,423
3 Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances Irith Wiegand, Kai Hilpert, Robert E. W. Hancock · Nature Protocols 17 Jan 2008 6,274
4 A simple practice guide for dose conversion between animals and human Anroop Balachandran Nair, Shery Jacob · Journal of Basic and Clinical Pharmacy Open access 2016 6,160
5 Microplastics as contaminants in the marine environment: A review Matthew Cole, Pennie Lindeque, Claudia Halsband et al. · Marine Pollution Bulletin Open access 17 Oct 2011 6,043
6 Origins and Evolution of Antibiotic Resistance JULIAN E. DAVIES, Dorothy Davies · Microbiology and Molecular Biology Reviews ReviewOpen access 30 Aug 2010 5,866
7 Identification of acquired antimicrobial resistance genes Ea Zankari, Henrik Hasman, Salvatore Cosentino et al. · Journal of Antimicrobial Chemotherapy Open access 10 Jul 2012 5,243
8 Fish bioaccumulation and biomarkers in environmental risk assessment: a review Ron van der Oost, Jonny Beyer, Nico Vermeulen · Environmental Toxicology and Pharmacology 10 Dec 2002 4,897
9 Pharmaceuticals and personal care products in the environment: agents of subtle change? Christian G. Daughton, Thomas A. Ternes · Environmental Health Perspectives Open access Dec 1999 4,496
10 Antibiotics in the aquatic environment – A review – Part I Klaus Kümmerer · Chemosphere 31 Jan 2009 4,483
11 Molecular mechanisms of antibiotic resistance Jessica M. A. Blair, Mark Alexander Webber, Alison J. Baylay et al. · Nature Reviews Microbiology Review Dec 2014 4,101
12 The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen Morimitsu Nishikimi, N. Appaji Rao, Kunio Yagi · Biochemical and Biophysical Research Communications 1972 4,097
13 The pollution of the marine environment by plastic debris: a review José G. B. Derraik · Marine Pollution Bulletin Sep 2002 4,062
14 Global trends in antimicrobial use in food animals Thomas P. Van Boeckel, Charles H. Brower, Marius Gilbert et al. · Proceedings of the National Academy of Sciences Open access 19 Mar 2015 4,021
15 A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment Yunlong Luo, Wenshan Guo, Huu Hao Ngo et al. · The Science of The Total Environment Open access 4 Jan 2014 3,980
16 Comprehensive Evaluation of Antibiotics Emission and Fate in the River Basins of China: Source Analysis, Multimedia Modeling, and Linkage to Bacterial Resistance Qian-Qian Zhang, Guang‐Guo Ying, Chang‐Gui Pan et al. · Environmental Science & Technology 11 May 2015 3,925
17 The Challenge of Micropollutants in Aquatic Systems René P. Schwarzenbach, Beate Isabella Escher, Kathrin Fenner et al. · Science Open access 24 Aug 2006 3,726
18 ResFinder 4.0 for predictions of phenotypes from genotypes Valeria Bortolaia et al. · Journal of Antimicrobial Chemotherapy Open access 16 Jul 2020 3,475
19 Occurrence of drugs in German sewage treatment plants and rivers Thomas A. Ternes · Water Research Nov 1998 3,419
20 A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment Ajit Kumar Sarmah, Michael T. Meyer, Alistair B. A. Boxall · Chemosphere 9 May 2006 3,337
21 Occurrence, fate and effects of pharmaceutical substances in the environment- A review Bent Halling‐Sørensen, Søren Nors Nielsen, P.F. Lanzky et al. · Chemosphere 1998 3,271
22 Ecotoxicology of human pharmaceuticals Karl Fent, Anna A. Weston, Daniel Caminada · Aquatic Toxicology 28 Oct 2005 3,203
23 Outpatient antibiotic use in Europe and association with resistance: a cross-national database study Herman Goossens, Matus Ferech, Robert Vander Stichele et al. · The Lancet Feb 2005 3,097
24 Antibiotic resistance in the environment D. G. Joakim Larsson, Carl‐Fredrik Flach · Nature Reviews Microbiology ReviewOpen access 4 Nov 2021 3,086
25 Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data Thomas Heberer · Toxicology Letters May 2002 2,977
26 Advantages and disadvantages of techniques used for wastewater treatment Grégorio Crini, Éric Lichtfouse · Environmental Chemistry Letters 30 Jul 2018 2,938
27 Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment Gerald T. Ankley, Richard S. Bennett, Russell J. Erickson et al. · Environmental Toxicology and Chemistry Open access 9 Nov 2009 2,710
28 Understanding the mechanisms and drivers of antimicrobial resistance Alison Holmes, Luke S. P. Moore, Arnfinn Sundsfjord et al. · The Lancet Open access 18 Nov 2015 2,697
29 Mechanisms of Antibiotic Resistance Jose Manuel Munita, César A. Arias · Microbiology Spectrum Open access 25 Mar 2016 2,653
30 Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods Manvendra Patel, Rahul Kumar, Kamal Kishor et al. · Chemical Reviews ReviewOpen access 4 Mar 2019 2,639
31 A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring Bruce Petrie, Ruth Barden, Barbara Kasprzyk‐Hordern · Water Research Open access 10 Sep 2014 2,620
32 Antibiotic resistance: a rundown of a global crisis Bilal Aslam, Wei Wang, Muhammad Arshad et al. · Infection and Drug Resistance Open access Oct 2018 2,606
33 Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: A review Luigi Rizzo, Célia M. Manaia, Christophe Merlin et al. · The Science of The Total Environment Open access 7 Feb 2013 2,501
34 Diverse and abundant antibiotic resistance genes in Chinese swine farms Yong‐Guan Zhu, Timothy A. Johnson, Jian-Qiang Su et al. · Proceedings of the National Academy of Sciences Open access 11 Feb 2013 2,478
35 Ozonation of drinking water: Part I. Oxidation kinetics and product formation Urs von Gunten · Water Research Open access 28 Feb 2003 2,448
36 Tackling antibiotic resistance: the environmental framework Thomas Ulrich Berendonk, Célia M. Manaia, Christophe Merlin et al. · Nature Reviews Microbiology Review 30 Mar 2015 2,381
37 The Comprehensive Antibiotic Resistance Database Andrew G. McArthur et al. · Antimicrobial Agents and Chemotherapy Open access 6 May 2013 2,365
38 Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment Felipe C. Cabello · Environmental Microbiology 24 May 2006 2,340
39 Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data Thomas P. Van Boeckel, Sumanth Gandra, Ashvin Ashok et al. · The Lancet Infectious Diseases 9 Jul 2014 2,324
40 Call of the wild: antibiotic resistance genes in natural environments Heather K. Allen, Justin J. Donato, Helena Huimi Wang et al. · Nature Reviews Microbiology Review Mar 2010 2,310
41 Food Animals and Antimicrobials: Impacts on Human Health Bonnie M. Marshall, Stuart B. Levy · Clinical Microbiology Reviews Open access Oct 2011 2,265
42 Occurrence of pharmaceutical compounds in urban wastewater: Removal, mass load and environmental risk after a secondary treatment—A review Paola Verlicchi, Mustafa Al Aukidy, Elena Zambello · The Science of The Total Environment 12 May 2012 2,170
43 Occurrence of antibiotics in the aquatic environment Roman Hirsch, Thomas A. Ternes, Klaus Haberer et al. · The Science of The Total Environment 1999 2,141
44 The Ames Salmonella/microsome mutagenicity assay Kristien E. Mortelmans, Errol Zeiger · Mutation research. Fundamental and molecular mechanisms of mutagenesis Nov 2000 2,113
45 Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials José Luis Martínez · Frontiers in Microbiology Open access 2012 2,109
46 Collapse of a fish population after exposure to a synthetic estrogen Karen A. Kidd, Paul J. Blanchfield, Kenneth H. Mills et al. · Proceedings of the National Academy of Sciences Open access 22 May 2007 2,097
47 Reactions of chlorine with inorganic and organic compounds during water treatment—Kinetics and mechanisms: A critical review Marie Deborde, Urs von Gunten · Water Research Open access 27 Jul 2007 2,065
48 Antibiotics and antibiotic resistance in water environments Fernando Baquero, José Luis Martínez, Rafael Cantón · Current Opinion in Biotechnology Review Jun 2008 2,064
49 Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment Anekwe Jennifer Ebele, Mohamed Abou‐Elwafa Abdallah, Stuart Harrad · Emerging contaminants Open access 5 Jan 2017 2,029
50 Antimicrobial Resistance: Implications and Costs Porooshat Dadgostar · Infection and Drug Resistance Open access Dec 2019 2,027

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.