Most cited papers in Phytochemistry and Bioactive Compounds
What are the most cited papers in Phytochemistry and Bioactive Compounds?
The most cited paper in Phytochemistry and Bioactive Compounds is "Interleukin-1 polymorphisms associated with increased risk of gastric cancer" (Emad M. El-Omar, Mary N Carrington, Wong-Ho Chow et al., 2000), with 2,384 citations. Next come "Distribution of Menaquinones in Actinomycetes and Corynebacteria" (2,293) and "Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine" (1,410).
Showing 50 of 100 papers. Every paper with more than 211 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Interleukin-1 polymorphisms associated with increased risk of gastric cancer Emad M. El-Omar, Mary N Carrington, Wong-Ho Chow et al. · Nature | 23 Mar 2000 | 2,384 |
| 2 | Distribution of Menaquinones in Actinomycetes and Corynebacteria M.D. Collins, T. Pirouz, Michael Goodfellow et al. · Journal of General Microbiology | Jun 1977 | 2,293 |
| 3 | Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine Michelino Di Rosa, J. P. Giroud, D. A. Willoughby · The Journal of Pathology | May 1971 | 1,410 |
| 4 | The Therapeutic Potential of Naringenin: A Review of Clinical Trials Bahare Salehi, Patrick Valère Tsouh Fokou, Mehdi Sharifi‐Rad et al. · Pharmaceuticals | 10 Jan 2019 | 819 |
| 5 | Saponins as cytotoxic agents: a review Irma Podolak, Agnieszka Galanty, Danuta Sobolewska · Phytochemistry Reviews | 24 Jun 2010 | 706 |
| 6 | Clinical Practice Guidelines for the Management of Sporotrichosis: 2007 Update by the Infectious Diseases Society of America Carol A. Kauffman, Beatriz Bustamante, Stanley W. Chapman et al. · Clinical Infectious Diseases | 15 Nov 2007 | 572 |
| 7 | Serum and glucocorticoid‐inducible kinase (SGK) is a target of the PI 3‐kinase‐stimulated signaling pathway Jongsun Park, Meredith L.L. Leong, Patricia Buse et al. · The EMBO Journal | Jun 1999 | 560 |
| 8 | Cardiac Glycosides as Novel Cancer Therapeutic Agents Robert Alan Newman, Pei Yang, Alison D. Pawlus et al. · Molecular Interventions | Feb 2008 | 526 |
| 9 | A Drug over the Millennia : Pharmacognosy, Chemistry, and Pharmacology of Licorice Shoji SHIBATA · YAKUGAKU ZASSHI | 2000 | 522 |
| 10 | Chemical and Pharmacological Research of the Plants in Genus Euphorbia Qing‐Wen Shi, Xiao-Hui Su, Hiromasa Kiyota · Chemical Reviews | 25 Sep 2008 | 500 |
| 11 | Toxic cardenolides: chemical ecology and coevolution of specialized plant–herbivore interactions Anurag A. Agrawal, Georg Petschenka, Robin A. Bingham et al. · New Phytologist | 31 Jan 2012 | 489 |
| 12 | Plant-derived compounds in clinical trials Arvind Saklani, Samuel K. Kutty · Drug Discovery Today | Dec 2007 | 486 |
| 13 | Potent selective inhibitors of protein kinase C Peter D. Davis, Christopher H. Hill, Elizabeth Keech et al. · FEBS Letters | 18 Dec 1989 | 480 |
| 14 | Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo Juhua Chen, Payaningal R. Somanath, Olga V. Razorenova et al. · Nature Medicine | 16 Oct 2005 | 463 |
| 15 | Mucopolysaccharidosis I: Management and Treatment Guidelines Joseph Muenzer, J. E. Wraith, Lorne A. Clarke et al. · PEDIATRICS | 29 Dec 2008 | 462 |
| 16 | Verbascoside — A review of its occurrence, (bio)synthesis and pharmacological significance Kalina Iv. Alipieva, Liudmila G. Korkina, İlkay Erdoğan Orhan et al. · Biotechnology Advances | 15 Jul 2014 | 461 |
| 17 | Biological properties of carrageenan Massimo Di Rosa · Journal of Pharmacy and Pharmacology | Feb 1972 | 459 |
| 18 | Potentiating effect of β-caryophyllene on anticancer activity of α-humulene, isocaryophyllene and paclitaxel Jean Legault, André Pichette · Journal of Pharmacy and Pharmacology | 21 Nov 2007 | 452 |
| 19 | Biological activity of limonoids from the rutales Donald E. Champagne, Opender Koul, Murray B. Isman et al. · Phytochemistry | Feb 1992 | 450 |
| 20 | VEGF signalling: integration and multi-tasking in endothelial cell biology Ian C. Zachary · Biochemical Society Transactions | Dec 2003 | 430 |
| 21 | Mechanisms of action of methotrexate Laurent Genestier, Romain Paillot, Laurence Quéméneur et al. · Immunopharmacology | May 2000 | 427 |
| 22 | Brefeldin A Pierre Teilhard de Chardin, Frank McCormick · Cell | Apr 1999 | 425 |
| 23 | Azaphilones: Chemistry and Biology Jin‐Ming Gao, Shengxiang Yang, Jianchun Qin · Chemical Reviews | 12 Apr 2013 | 409 |
| 24 | Anti-Inflammatory Compounds of Plant Origin. Part II. Modulation of Pro-Inflammatory Cytokines, Chemokines and Adhesion Molecules João Β. Calixto, Maria M. Campos, Michel Fleith Otuki et al. · Planta Medica | Feb 2004 | 409 |
| 25 | Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology Shadma Wahab, Sivakumar Annadurai, Shahabe Saquib Abullais et al. · Plants | 14 Dec 2021 | 399 |
| 26 | Epidemiology and Diagnosis of H elicobacter pylori infection Andreas F. Mentis, Philippe Lehours, Françis Mégraud · Helicobacter | Sep 2015 | 398 |
| 27 | Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa Brendan J.R. Whittle, Gerald A Higgs, K.E. Eakins et al. · Nature | Mar 1980 | 396 |
| 28 | A history of the therapeutic use of liquorice in Europe Cristina Fiore, Michael Eisenhut, Eugenio Ragazzi et al. · Journal of Ethnopharmacology | 23 Jun 2005 | 390 |
| 29 | Screening of Yemeni medicinal plants for antibacterial and cytotoxic activities Nasser A. Awadh Ali, W.-D. Jülich, C Kusnick et al. · Journal of Ethnopharmacology | Feb 2001 | 384 |
| 30 | Postmenopausal Estrogen and Prevention Bias Elizabeth L Barrett-Connor · Annals of Internal Medicine | 15 Sep 1991 | 380 |
| 31 | Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds Alfonsus Alvin, Kristin I. Miller, Brett Anthony Neilan · Microbiological Research | 15 Jan 2014 | 377 |
| 32 | Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research—The ConPhyMP—Guidelines12 Michael Heinrich, Banaz Jalil, Mona Abdel‐Tawab et al. · Frontiers in Pharmacology | 13 Sep 2022 | 371 |
| 33 | Anti-Helicobacter pylori flavonoids from licorice extract Toshio Fukai, Ai Marumo, Kiyoshi Kaitou et al. · Life Sciences | Aug 2002 | 370 |
| 34 | The carbohydrates of the Jerusalem artichoke and other Compositae John S. D. Bacon, Jack R. Edelman · Biochemical Journal | 1951 | 366 |
| 35 | Preliminary screening of some traditional zulu medicinal plants for anti-inflammatory and anti-microbial activities Johnson Lin, Andy Rowland Opoku, M. Geheeb-Keller et al. · Journal of Ethnopharmacology | Dec 1999 | 365 |
| 36 | Colonization of gnotobiotic piglets by Helicobacter pylori deficient in two flagellin genes Kathryn A. Eaton, Sebastian Suerbaum, Christine Josenhans et al. · Infection and Immunity | Jul 1996 | 360 |
| 37 | Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection Erik De Clercq · Medicinal Research Reviews | 2000 | 358 |
| 38 | Revisiting the ancient concept of botanical therapeutics Barbara M. Schmidt, David Ribnicky, Peter E. Lipsky et al. · Nature Chemical Biology | 19 Jun 2007 | 358 |
| 39 | Phytopharmacological overview of Tribulus terrestris Saurabh P. Chhatre, Tanuja Manoj Nesari, Divya M. Kanchan et al. · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review | 2014 | 356 |
| 40 | Psoriasis is associated with lipid abnormalities at the onset of skin disease Lotus Mallbris, Fredrik N. Granath, Anders Hamsten et al. · Journal of the American Academy of Dermatology | 20 Jan 2006 | 354 |
| 41 | Sesquiterpenes from Clove (Eugenia caryophyllata) as Potential Anticarcinogenic Agents Guo-Qiang Zheng, Patrick M. J. Kenney, Luke K. T. Lam · Journal of Natural Products | Jul 1992 | 345 |
| 42 | Screening of Zulu medicinal plants for prostaglandin-synthesis inhibitors Anna K. Jäger, Anne Hutchings, Johannes van Staden · Journal of Ethnopharmacology | Jun 1996 | 345 |
| 43 | A broad review of commercially important southern African medicinal plants B.-E. Van Wyk · Journal of Ethnopharmacology | 4 Jun 2008 | 342 |
| 44 | The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB. Heike Luise Pahl, B Krauss, Klaus Schulze‐Osthoff et al. · The Journal of Experimental Medicine | Apr 1996 | 337 |
| 45 | Cytotoxic activity screening of some indigenous Thai plants Pokpong Prayong, Sahapat Barusrux, Natthida Weerapreeyakul · Fitoterapia | 14 Jul 2008 | 334 |
| 46 | Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark Machindra J. Chavan, Pravin Wakte, D. B. Shinde · Phytomedicine | 3 Jul 2009 | 327 |
| 47 | Chemical Biology of Epothilones Kyriacos Costa Nicolaou, Frank Roschangar, Dionisios Vourloumis · Angewandte Chemie International Edition | 17 Aug 1998 | 325 |
| 48 | Selectivity of Neutrophil 5-Lipoxygenase and Cyclo-oxygenase Inhibition by an Anti-inflammatory Flavonoid Glycoside and Related Aglycone Flavonoids M.A. Moroney, M. José Alcaraz, Robert A. Forder et al. · Journal of Pharmacy and Pharmacology | Nov 1988 | 324 |
| 49 | Anti-inflammatory Properties of the Monoterpene 1.8-cineole: Current Evidence for Co-medication in Inflammatory Airway Diseases Uwe R. Juergens · Drug Research | 15 May 2014 | 294 |
| 50 | Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review Shashi Alok, Sanjay Jain, Amita Verma et al. · Asian Pacific Journal of Tropical Disease | 26 Mar 2013 | 292 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.