Most cited papers in Plant-derived Lignans Synthesis and Bioactivity
What are the most cited papers in Plant-derived Lignans Synthesis and Bioactivity?
The most cited paper in Plant-derived Lignans Synthesis and Bioactivity is "Plants as a source of anti-cancer agents" (Gordon M. L. Cragg, David J. Newman, 2005), with 2,046 citations. Next come "Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice" (1,087) and "Phytochemistry of the genus Piper" (962).
Showing 50 of 100 papers. Every paper with more than 211 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Plants as a source of anti-cancer agents Gordon M. L. Cragg, David J. Newman · Journal of Ethnopharmacology | 13 Jul 2005 | 2,046 |
| 2 | Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice Amit S. Choudhari, Pallavi C. Mandave, Manasi Deshpande et al. · Frontiers in Pharmacology | 28 Jan 2020 | 1,087 |
| 3 | Phytochemistry of the genus Piper Virinder Singh Parmar, Subhash Chand Jain, Kirpal S. Bisht et al. · Phytochemistry | Oct 1997 | 962 |
| 4 | Etoposide: four decades of development of a topoisomerase II inhibitor Kenneth R. Hande · European Journal of Cancer | Sep 1998 | 952 |
| 5 | Immunomodulation and Anti-Cancer Activity of Polysaccharide-Protein Complexes Vincent E. C. Ooi, Fang Liu · Current Medicinal Chemistry | Jul 2000 | 872 |
| 6 | Stereoselective Bimolecular Phenoxy Radical Coupling by an Auxiliary (Dirigent) Protein Without an Active Center Laurence B Davin, Huai-Bin Wang, Anastasia L. Crowell et al. · Science | 17 Jan 1997 | 768 |
| 7 | The cell biology of lignification in higher plants Jaime Barros, Henrik Serk, Irene Granlund et al. · Annals of Botany | 15 Apr 2015 | 737 |
| 8 | Natural products for cancer chemotherapy Arnold L. Demain, Preeti Vaishnav · Microbial Biotechnology | 18 Nov 2010 | 734 |
| 9 | Acute Myeloid Leukemia in Children Treated with Epipodophyllotoxins for Acute Lymphoblastic Leukemia Ching‐Hon Pui, Raul Correa Ribeiro, Michael L. Hancock et al. · New England Journal of Medicine | 12 Dec 1991 | 723 |
| 10 | Antioxidant Effects of Some Ginger Constituents Hiroe Kikuzaki, Nobuji Nakatani · Journal of Food Science | Nov 1993 | 723 |
| 11 | The Role of Polyphenols in Abiotic Stress Response: The Influence of Molecular Structure Dunja Šamec, Erna Karalija, Ivana Šola et al. · Plants | 8 Jan 2021 | 687 |
| 12 | Antioxidant activity of burdock (Arctium lappa Linné): Its scavenging effect on free‐radical and active oxygen Pin‐Der Duh · Journal of the American Oil Chemists Society | Apr 1998 | 675 |
| 13 | Mammalian ceramide synthases Michal Levy, Anthony H. Futerman · IUBMB Life | 10 Mar 2010 | 644 |
| 14 | NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches Farzane Sivandzade, Shikha Prasad, Aditya Bhalerao et al. · Redox Biology | 28 Nov 2018 | 642 |
| 15 | Biological activities of lignans W.Donald MacRae, G.H.N. Towers · Phytochemistry | May 1984 | 564 |
| 16 | Roles of the reactive oxygen species-generating peroxidase reactions in plant defense and growth induction Tomonori Kawano · Plant Cell Reports | 22 Mar 2003 | 555 |
| 17 | Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives Marina Gordaliza, Pedro Antonio García-Encina, José M. Miguel del Corral et al. · Toxicon | 22 Jun 2004 | 547 |
| 18 | Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine Alexander Panossian, Georg Wikman · Journal of Ethnopharmacology | 25 Apr 2008 | 524 |
| 19 | An update on bioactive plant lignans Muhammad Saleem, Hyoung Ja Kim, Muhammad Shaiq Ali et al. · Natural Product Reports | 2005 | 505 |
| 20 | Recent advances in research on lignans and neolignans Rémy Bertrand Teponno, Souvik Kusari, Michael Spiteller · Natural Product Reports | 2016 | 503 |
| 21 | Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone Warren Lau, Elizabeth S. Sattely · Science | 10 Sep 2015 | 498 |
| 22 | Therapeutic applications of compounds in the Magnolia family Young‐Jung Lee, Yoot Mo Lee, Chong‐Kil Lee et al. · Pharmacology & Therapeutics | 27 Jan 2011 | 493 |
| 23 | Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Warren E. Ross, Tom Rowe, Bonnie S. Glisson et al. · PubMed | Dec 1984 | 460 |
| 24 | Lipoxygenases: Occurrence, functions and catalysis Alena Liavonchanka, Ivo Feußner · Journal of Plant Physiology | 29 Dec 2005 | 454 |
| 25 | Plant derived substances with anti-cancer activity: from folklore to practice Marcelo Fridlender, Yoram Kapulnik, Hinanit Koltai · Frontiers in Plant Science | Oct 2015 | 422 |
| 26 | Melissa officinalis L. – A review of its traditional uses, phytochemistry and pharmacology Abolfazl Shakeri, Amirhossein Sahebkar, Behjat Javadi · Journal of Ethnopharmacology | 8 May 2016 | 387 |
| 27 | Eucommia ulmoides Oliv.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine Xirui He, Jinhui Wang, Maoxing Li et al. · Journal of Ethnopharmacology | Dec 2013 | 369 |
| 28 | Podophyllotoxin Camilo Canel, Rita M. Moraes, Franck Emmanuel Dayan et al. · Phytochemistry | May 2000 | 363 |
| 29 | Endophyte Fungal Isolates fromPodophyllumpeltatumProduce Podophyllotoxin Amy L. Eyberger, Rajeswari Dondapati, John Roger Porter · Journal of Natural Products | Aug 2006 | 362 |
| 30 | β-Caryophyllene: A Sesquiterpene with Countless Biological Properties Fabrizio Francomano, Anna Caruso, Alexia Barbarossa et al. · Applied Sciences | 11 Dec 2019 | 351 |
| 31 | Discovery of podophyllotoxins Thierry Imbert · Biochimie | Mar 1998 | 347 |
| 32 | Lignin polymerization: how do plants manage the chemistry so well? Yuki Tobimatsu, Mathias Schuetz · Current Opinion in Biotechnology | 22 Oct 2018 | 340 |
| 33 | Antiviral activity of Plantago major extracts and related compounds in vitro Luciano Chiang, Wen Chin Chiang, Mei‐Yin Chang et al. · Antiviral Research | Jul 2002 | 336 |
| 34 | Identification of Arctigenin as an Antitumor Agent Having the Ability to Eliminate the Tolerance of Cancer Cells to Nutrient Starvation Suresh Awale, Jie Lu, Surya Kant Kalauni et al. · Cancer Research | Feb 2006 | 330 |
| 35 | Diversity in lignan biosynthesis Toshiaki Umezawa · Phytochemistry Reviews | 2003 | 329 |
| 36 | Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies Agnieszka Szopa, Radosław J. Ekiert, Halina Ekiert · Phytochemistry Reviews | 12 May 2016 | 328 |
| 37 | Dirigent Proteins and Dirigent Sites Explain the Mystery of Specificity of Radical Precursor Coupling in Lignan and Lignin Biosynthesis Laurence B Davin, Norman Lewis · PLANT PHYSIOLOGY | Jun 2000 | 328 |
| 38 | The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans Satish Chandra Puri, Asiya Nazir, Raman Chawla et al. · Journal of Biotechnology | 22 Dec 2005 | 325 |
| 39 | Pirfenidone for Diabetic Nephropathy Kumar Sharma, Joachim H. Ix, Anna Vachaparampil Mathew et al. · Journal of the American Society of Nephrology | 21 Apr 2011 | 320 |
| 40 | Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2 Kevin J. French, Yan Zhuang, Lynn W. Maines et al. · Journal of Pharmacology and Experimental Therapeutics | 8 Jan 2010 | 320 |
| 41 | The role of ceramide in cell signaling David K. Perry, Yusuf Awni Hannun · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | Dec 1998 | 319 |
| 42 | Dirigent proteins in plants: modulating cell wall metabolism during abiotic and biotic stress exposure Candelas Paniagua, Anna Bílková, P. Jackson et al. · Journal of Experimental Botany | 7 Apr 2017 | 315 |
| 43 | The Course of Etoposide-induced Apoptosis from Damage to DNA and p53 Activation to Mitochondrial Release of Cytochromec Natalie O. Karpinich, Marco Tafani, Ronald J. Rothman et al. · Journal of Biological Chemistry | May 2002 | 313 |
| 44 | Lignans, neolignans, and related compounds Robert S. Ward · Natural Product Reports | 1995 | 312 |
| 45 | Intermolecular Enolate Heterocoupling: Scope, Mechanism, and Application Michael P. DeMartino, Ke Chen, Phil S. Baran · Journal of the American Chemical Society | 5 Aug 2008 | 306 |
| 46 | Molecular mechanisms of etoposide. Alessandra Montecucco, Francesca Zanetta, Giuseppe Biamonti · PubMed | 2015 | 302 |
| 47 | Schisandra chinensis (Turcz.) Baill Juan L. Hancke, Rafael Agustin Burgos, F. Ahumada · Fitoterapia | Oct 1999 | 300 |
| 48 | Aspergillus fumigatusFresenius, an endophytic fungus fromJuniperus communisL. Horstmann as a novel source of the anticancer pro-drug deoxypodophyllotoxin Souvik Kusari, Marc Lamshöft, Michael Spiteller · Journal of Applied Microbiology | 17 Apr 2009 | 295 |
| 49 | Nomenclature of Lignans and Neolignans (IUPAC Recommendations 2000) Gerard P. Moss · Pure and Applied Chemistry | 2000 | 292 |
| 50 | The excretion of lignans in rats — evidence for an intestinal bacterial source for this new group of compounds Magnus Axelson, K.D.R. Setchell · FEBS Letters | 26 Jan 1981 | 292 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.