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Plant-derived Lignans Synthesis and Bioactivity

Plant-derived Lignans Synthesis and Bioactivity is a research topic within Molecular Biology. Science Explorer counts 5.8k research works in it since 1951. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the biosynthesis, pharmacological activities, and medicinal applications of lignans, including compounds such as podophyllotoxin, schisandrin, arctigenin, and related derivatives. It covers research on various plant sources, enzymatic pathways, cytotoxicity, anti-inflammatory effects, and potential therapeutic uses of lignans in cancer treatment, neuroprotection, hepatoprotection, and antimicrobial activities.

  • Lignans
  • Biosynthesis
  • Pharmacological Activities
  • Anticancer Agents
  • Antioxidant
  • Medicinal Plants
  • Podophyllotoxin
  • Schisandra chinensis
  • Arctium lappa
  • Dirigent Proteins
Research works
5.8k
fractional, since 1951
In the world top 10%
576
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+18%
the tick is no change
Largest producer
China
59% of the 10 largest, 2022-now
Plant-derived Lignans Synthesis and Bioactivity

Which countries lead Plant-derived Lignans Synthesis and Bioactivity research?

By volume, China and India publish the most (507 and 90 works in 2022-now).

By volume, 2022-now

  1. 1 China 507 works
  2. 2 India 90 works
  3. 3 South Korea 51 works
  4. 4 Indonesia 48 works
  5. 5 United States 45 works
  6. 6 Japan 40 works
  7. 7 Vietnam 23 works
  8. 8 Brazil 22 works
  9. 9 Taiwan 20 works
  10. 10 Iran 18 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 58.7%India: 10.4%South Korea: 5.9%Indonesia: 5.5%6 others listed: 19.4%59%largest
China507 · 58.7%India90 · 10.4%South Korea51 · 5.9%Indonesia48 · 5.5%6 others listed168 · 19.4%

Shares of the rows listed above, not of the whole node.

Which institutions lead Plant-derived Lignans Synthesis and Bioactivity research?

By volume in 2022-now, Chinese Academy of Medical Sciences & Peking Union Medical College publishes the most Plant-derived Lignans Synthesis and Bioactivity research, followed by Chinese Academy of Sciences and Heilongjiang University of Chinese Medicine.

Who are the leading researchers in Plant-derived Lignans Synthesis and Bioactivity?

The most-cited researchers publishing on Plant-derived Lignans Synthesis and Bioactivity include Eric B. Rimm and Frank J. Gonzalez.

  1. 1 Eric B. Rimm United States 153k citations
  2. 2 Frank J. Gonzalez United States 153k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Plant-derived Lignans Synthesis and Bioactivity?

The most cited paper in Plant-derived Lignans Synthesis and Bioactivity is "Plants as a source of anti-cancer agents" (Gordon M. L. Cragg, David J. Newman, 2005), with 2,046 citations. Next come "Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice" (1,087) and "Phytochemistry of the genus Piper" (962).

Most cited papers
#PaperReleasedCitations
1 Plants as a source of anti-cancer agents Gordon M. L. Cragg, David J. Newman · Journal of Ethnopharmacology Open access 13 Jul 2005 2,046
2 Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice Amit S. Choudhari, Pallavi C. Mandave, Manasi Deshpande et al. · Frontiers in Pharmacology Open access 28 Jan 2020 1,087
3 Phytochemistry of the genus Piper Virinder Singh Parmar, Subhash Chand Jain, Kirpal S. Bisht et al. · Phytochemistry Oct 1997 962
4 Etoposide: four decades of development of a topoisomerase II inhibitor Kenneth R. Hande · European Journal of Cancer Sep 1998 952
5 Immunomodulation and Anti-Cancer Activity of Polysaccharide-Protein Complexes Vincent E. C. Ooi, Fang Liu · Current Medicinal Chemistry Jul 2000 872
All 100 most cited papers, with filters and sorting

Where is Plant-derived Lignans Synthesis and Bioactivity research done?

The largest centres of Plant-derived Lignans Synthesis and Bioactivity research in 2022-now are Beijing (China), Guangzhou (China), Shanghai (China) and Nanjing (China).

Largest cities, 2022-now

  1. 1 BeijingChina 65 works
  2. 2 GuangzhouChina 25 works
  3. 3 ShanghaiChina 23 works
  4. 4 NanjingChina 21 works
  5. 5 HarbinChina 19 works
  6. 6 ShenyangChina 18 works
  7. 7 ChangshaChina 18 works
  8. 8 ChengduChina 18 works
  9. 9 SeoulSouth Korea 17 works
  10. 10 KunmingChina 16 works
See Plant-derived Lignans Synthesis and Bioactivity on the map

Where is the best place to study Plant-derived Lignans Synthesis and Bioactivity?

Among universities, judged by research, Chinese Academy of Medical Sciences & Peking Union Medical College, Heilongjiang University of Chinese Medicine and Shenyang Pharmaceutical University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 56.08.8%18.4×19 +31.7%
2Heilongjiang University of Chinese MedicineChina 51.822.4%108.0×9 +159.0%
3Shenyang Pharmaceutical UniversityChina 4.14.8%71.5×9 -8.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Plant-derived Lignans Synthesis and Bioactivity, country by country

Is Plant-derived Lignans Synthesis and Bioactivity research growing?

Output in 2022-2025 was 18% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Plant-derived Lignans Synthesis and Bioactivity.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Plant-derived Lignans Synthesis and Bioactivity as a percentage of every work published that year, 0.0040% in 2024.

still counting0.0050%0.010%Plant-derived Lignans Synthesis and Bioactivity0.0047% in 202519801990200020102020

Fractional works of Plant-derived Lignans Synthesis and Bioactivity over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Plant-derived Lignans Synthesis and Bioactivity10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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