Most cited papers in Process Optimization and Integration
What are the most cited papers in Process Optimization and Integration?
The most cited paper in Process Optimization and Integration is "Decision-Making in a Fuzzy Environment" (Richard Bellman, L. A. Zadeh, 1970), with 6,821 citations. Next come "What is flux balance analysis?" (4,197) and "Humidity fixed points of binary saturated aqueous solutions" (3,996).
Showing 50 of 100 papers. Every paper with more than 569 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Decision-Making in a Fuzzy Environment Richard Bellman, L. A. Zadeh · Management Science | Dec 1970 | 6,821 |
| 2 | What is flux balance analysis? Jeffrey D. Orth, Ines Thiele, Bernhard Ørn Palsson · Nature Biotechnology | Mar 2010 | 4,197 |
| 3 | Humidity fixed points of binary saturated aqueous solutions Lewis Greenspan · Journal of Research of the National Bureau of Standards Section A Physics and Chemistry | 1977 | 3,996 |
| 4 | Generalized predictive control—Part I. The basic algorithm DAVID W. CLARKE, Coorous Mohtadi, P.S. Tuffs · Automatica | Mar 1987 | 3,792 |
| 5 | A plant-wide industrial process control problem James J. Downs, Ernest F. Vogel · Computers & Chemical Engineering | Mar 1993 | 3,313 |
| 6 | Technical aspects of biodiesel production by transesterification—a review Lekha Charan Meher, D VIDYASAGAR, S.N. Naik · Renewable and Sustainable Energy Reviews | 10 Dec 2004 | 3,270 |
| 7 | Control of systems integrating logic, dynamics, and constraints Alberto Bemporad, Manfred Morari · Automatica | Mar 1999 | 3,082 |
| 8 | Safe and Convenient Procedure for Solvent Purification Amy B. Pangborn, Michael A. Giardello, Robert Howard Grubbs et al. · Organometallics | 5 Mar 1996 | 2,754 |
| 9 | Chance-Constrained Programming A. Charnes, William White Cooper · Management Science | Oct 1959 | 2,753 |
| 10 | Continuous flow systems P.V. Danckwerts · Chemical Engineering Science | Feb 1953 | 2,619 |
| 11 | A General Energy Balance for Battery Systems Dawn M. Bernardi, Ellen M. Pawlikowski, John Steven Newman · Journal of The Electrochemical Society | 1985 | 2,527 |
| 12 | Green and Sustainable Solvents in Chemical Processes Coby J. Clarke, Wei-Chien Tu, Oliver Levers et al. · Chemical Reviews | 4 Jan 2018 | 2,068 |
| 13 | Management Models and Industrial Applications of Linear Programming A. Charnes, William White Cooper · Management Science | Oct 1957 | 1,909 |
| 14 | What is a green solvent? A comprehensive framework for the environmental assessment of solvents Christian Capello, Ulrich Fischer, Konrad Hungerbühler · Green Chemistry | 2007 | 1,902 |
| 15 | The E Factor: fifteen years on Roger A. Sheldon · Green Chemistry | 2007 | 1,668 |
| 16 | Computer simulation of liquids Charles L. Brooks · Journal of Solution Chemistry | 1989 | 1,552 |
| 17 | Carbon capture, storage and utilisation technologies: A critical analysis and comparison of their life cycle environmental impacts Rosa M. Cuéllar-Franca, Adisa Azapagic · Journal of CO2 Utilization | 20 Dec 2014 | 1,546 |
| 18 | The E factor 25 years on: the rise of green chemistry and sustainability Roger A. Sheldon · Green Chemistry | 30 Sep 2016 | 1,527 |
| 19 | Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients Bernhard Gutmann, David Cantillo, Christian Oliver Kappe · Angewandte Chemie International Edition | 18 May 2015 | 1,486 |
| 20 | Tools and techniques for solvent selection: green solvent selection guides Fergal P. Byrne, Saimeng Jin, Giulia Paggiola et al. · Sustainable Chemical Processes | 23 May 2016 | 1,422 |
| 21 | The pinch design method for heat exchanger networks Bodo Linnhoff, E. Hindmarsh · Chemical Engineering Science | 1983 | 1,375 |
| 22 | Theory and applications of HVAC control systems – A review of model predictive control (MPC) Abdul Afram, Farrokh Janabi‐Sharifi · Building and Environment | 25 Nov 2013 | 1,308 |
| 23 | Metrics of Green Chemistry and Sustainability: Past, Present, and Future Roger A. Sheldon · ACS Sustainable Chemistry & Engineering | 8 Nov 2017 | 1,289 |
| 24 | Designing for a green chemistry future Julie Beth Zimmerman, Paul T. Anastas, Hanno C. Erythropel et al. · Science | 23 Jan 2020 | 1,249 |
| 25 | Multi-objective Optimization Kalyanmoy Deb, Kalyanmoy Deb | 9 Jul 2013 | 1,249 |
| 26 | Estimating the global waste heat potential Clemens Forman, Ibrahim Kolawole Muritala, Robert Pardemann et al. · Renewable and Sustainable Energy Reviews | 13 Jan 2016 | 1,211 |
| 27 | A general algorithm for short-term scheduling of batch operations—I. MILP formulation Emilia M. Kondili, Constantinos C. Pantelides, R.W.H. Sargent · Computers & Chemical Engineering | Feb 1993 | 1,162 |
| 28 | SPECO: A systematic and general methodology for calculating efficiencies and costs in thermal systems Andrea Lazzaretto, George Tsatsaronis · Energy | 6 Jul 2005 | 1,147 |
| 29 | Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry Richard K. Henderson, Concepción Jiménez‐González, David J. C. Constable et al. · Green Chemistry | 2011 | 1,140 |
| 30 | Advancements in development and characterization of biodiesel: A review Yogesh Chandra Sharma, Bhaskar Singh, Siddh Nath Upadhyay · Fuel | 21 Feb 2008 | 1,126 |
| 31 | Encyclopedia of Chemical Technology Raymond E. Kirk, Donald F. Othmer, Sylvan H Newburger · Journal of AOAC INTERNATIONAL | Nov 1953 | 1,083 |
| 32 | Simultaneous optimization models for heat integration—II. Heat exchanger network synthesis Terrence F. Yee, I.E. Grossmann · Computers & Chemical Engineering | Oct 1990 | 1,074 |
| 33 | The Water-Gas Shift Reaction David S. Newsome · Catalysis Reviews | 1980 | 1,018 |
| 34 | Prospects of biodiesel production from vegetable oils in India B.K. Barnwal, M.P. Sharma · Renewable and Sustainable Energy Reviews | 13 Jul 2004 | 972 |
| 35 | Wastewater minimisation Y.P. Wang, Robin Smith · Chemical Engineering Science | Apr 1994 | 948 |
| 36 | Synthesis of heat exchanger networks: I. Systematic generation of energy optimal networks Bodo Linnhoff, John R. Flower · AIChE Journal | Jul 1978 | 933 |
| 37 | Practical Approaches to Green Solvents Joseph M. DeSimone · Science | 2 Aug 2002 | 927 |
| 38 | Metrics to ‘green’ chemistry—which are the best? David J. C. Constable, Alan D. Curzons, Virginia L. Cunningham · Green Chemistry | 2002 | 907 |
| 39 | An algorithmic framework for convex mixed integer nonlinear programs Pierre Bonami, Lorenz T. Biegler, Andrew R. Conn et al. · Discrete Optimization | Dec 2007 | 906 |
| 40 | Using the Right Green Yardstick: Why Process Mass Intensity Is Used in the Pharmaceutical Industry To Drive More Sustainable Processes Concepción Jiménez‐González, Celia S. Ponder, Quirinus B. Broxterman et al. · Organic Process Research & Development | 12 May 2011 | 901 |
| 41 | Green Chemistry: Science and Politics of Change Martyn Poliakoff, Jessica FitzPatrick, Trevor R. Farren et al. · Science | 2 Aug 2002 | 894 |
| 42 | Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production Sau L. Lee, Thomas F. O’Connor, Xiaochuan Yang et al. · Journal of Pharmaceutical Innovation | 18 Mar 2015 | 873 |
| 43 | Supercritical fluids: technology and application to food processing Gerd H. Brunner · Journal of Food Engineering | 14 Sep 2004 | 833 |
| 44 | State-of-the-art review of optimization methods for short-term scheduling of batch processes Carlos Alberto Méndez, Jaime Cerdá, Ignacio E. Grossmann et al. · Computers & Chemical Engineering | 18 Apr 2006 | 810 |
| 45 | Optimization of Chemical Processes JackW. Ponton · Chemical Engineering Science | 1989 | 778 |
| 46 | Chemical reaction network structure and the stability of complex isothermal reactors—I. The deficiency zero and deficiency one theorems Martin Feinberg · Chemical Engineering Science | 1987 | 775 |
| 47 | A review on novel processes of biodiesel production from waste cooking oil Amin Talebian‐Kiakalaieh, Nor Aishah Saidina Amin, Hossein Mazaheri · Applied Energy | 28 Dec 2012 | 773 |
| 48 | EcoScale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters Koen Van Aken, Lucjan Strękowski, Luc Patiny · Beilstein Journal of Organic Chemistry | 3 Mar 2006 | 770 |
| 49 | Smart manufacturing, manufacturing intelligence and demand-dynamic performance Jim Davis, Thomas F. Edgar, James B. Porter et al. · Computers & Chemical Engineering | 6 Jul 2012 | 765 |
| 50 | A combined penalty function and outer-approximation method for MINLP optimization J. Viswanathan, Ignacio E. Grossmann · Computers & Chemical Engineering | Jul 1990 | 749 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.