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Most cited papers in Protein Hydrolysis and Bioactive Peptides

Protein Hydrolysis and Bioactive Peptides

What are the most cited papers in Protein Hydrolysis and Bioactive Peptides?

The most cited paper in Protein Hydrolysis and Bioactive Peptides is "A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding" (Mark A. Bradford, 1976), with 225,381 citations. Next come "A standardised static in vitro digestion method suitable for food – an international consensus" (5,749) and "Colorimetric assay of catalase" (5,584).

Showing 50 of 100 papers. Every paper with more than 817 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding Mark A. Bradford · Analytical Biochemistry 7 May 1976 225,381
2 A standardised static in vitro digestion method suitable for food – an international consensus Mans Minekus et al. · Food & Function Open access 2014 5,749
3 Colorimetric assay of catalase Asru Kumar Sinha · Analytical Biochemistry Jun 1972 5,584
4 Defensins: antimicrobial peptides of innate immunity Tomas Ganz · Nature reviews. Immunology Review Sep 2003 3,100
5 Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis Scott W. Rogers, Rodney Wells, Martin C. RECHSTEINER · Science 17 Oct 1986 2,578
6 Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications Islem Younes, Marguerite Rinaudo · Marine Drugs Open access 2 Mar 2015 2,555
7 Bacteriocins: developing innate immunity for food Paul D. Cotter, Colin Hill, R. Paul Ross · Nature Reviews Microbiology Review Oct 2005 2,399
8 Probiotic Bacteria as Biological Control Agents in Aquaculture Laurent Verschuere, Geert Rombaut, Patrick Sorgeloos et al. · Microbiology and Molecular Biology Reviews ReviewOpen access Dec 2000 2,285
9 Molecular and Biotechnological Aspects of Microbial Proteases Mala B. Rao, Aparna M. Tanksale, Mohini S. Ghatge et al. · Microbiology and Molecular Biology Reviews ReviewOpen access Sep 1998 2,283
10 Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide Kazuhiko Tatemoto, Mats Carlquist, Viktor Mutt · Nature Apr 1982 2,281
11 Functional and bioactive properties of collagen and gelatin from alternative sources: A review María Carmen Gómez-Guillén, Begoña Giménez, María Elvira López-Caballero et al. · Food Hydrocolloids Open access 16 Feb 2011 2,050
12 Antimicrobial Peptides: An Emerging Category of Therapeutic Agents Margit Mahlapuu, Joakim Håkansson, Lovisa Ringstad et al. · Frontiers in Cellular and Infection Microbiology Open access 26 Dec 2016 1,971
13 Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science 22 Apr 1977 1,867
14 Biodegradation, biodistribution and toxicity of chitosan Thomas J. Kean, Maya Thanou · Advanced Drug Delivery Reviews Review 2 Oct 2009 1,823
15 Lactic acid bacteria as functional starter cultures for the food fermentation industry Frédéric Leroy, Luc De Vuyst · Trends in Food Science & Technology 6 Nov 2003 1,817
16 Improved Method for Determining Food Protein Degree of Hydrolysis Per Munk Nielsen, Daphne Elaine Leslie Petersen, C. Dambmann · Journal of Food Science Jun 2001 1,790
17 Bioactive peptides: Production and functionality Hannu J. T. Korhonen, Anne Pihlanto · International Dairy Journal 20 Feb 2006 1,740
18 Purification and properties Brian M. Cox, K E Opheim, H. Teschemacher et al. · Life Sciences Jun 1975 1,717
19 Antioxidative peptides from food proteins: A review Bahareh Sarmadi, Amin Ismail · Peptides Jul 2010 1,653
20 Health benefits of fermented foods: microbiota and beyond Maria L. Marco, Dustin D. Heeney, Sylvie Binda et al. · Current Opinion in Biotechnology ReviewOpen access 18 Dec 2016 1,650
21 The expanding scope of antimicrobial peptide structures and their modes of action Leonard Tu Nguyen, Evan F. Haney, Hans J. Vogel · Trends in biotechnology Review 21 Jun 2011 1,630
22 Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2 Carlos Maria Ferrario, Jewell A. Jessup, Mark C. Chappell et al. · Circulation 16 May 2005 1,618
23 Inhibition of Food Intake in Obese Subjects by Peptide YY 3–36 Rachel Louise Batterham, Mark A. Cohen, Sylvia Ellis et al. · New England Journal of Medicine 3 Sep 2003 1,596
24 Spectrophotometric Assay Using o-Phthaldialdehyde for Determination of Proteolysis in Milk and Isolated Milk Proteins Frank Church, Harold E. Swaisgood, David H. Porter et al. · Journal of Dairy Science Open access Jun 1983 1,546
25 The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami Robert E. Carraway, Susan E. Leeman · Journal of Biological Chemistry Open access Oct 1973 1,544
26 Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase Chad Vickers, Paul Hales, Virendar K. Kaushik et al. · Journal of Biological Chemistry Open access Apr 2002 1,434
27 Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state Christian J. Pike, Daniel J. Burdick, AJ Walencewicz et al. · Journal of Neuroscience Open access Apr 1993 1,432
28 Physico-chemical characteristics of goat and sheep milk Y.W. Park, Manuela Juárez, Maria‐Helena Ramos et al. · Small Ruminant Research 28 Oct 2006 1,424
29 Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults Edward S. Chambers et al. · Gut Open access 10 Dec 2014 1,422
30 Carrageenans: Biological properties, chemical modifications and structural analysis – A review Vanessa Leiria Campo, Daniel Fábio Kawano, Dílson Braz da Silva et al. · Carbohydrate Polymers Feb 2009 1,406
31 Formation of Methane by Bacterial Extracts E. A. Wolin, M. J. Wolin, RALPH S. WOLFE · Journal of Biological Chemistry Open access Aug 1963 1,400
32 Proteases and biological control A. H. Gordon · Nature 18 Nov 1976 1,382
33 Food proteins and their applications Patrick F. Fox · International Dairy Journal Jun 1997 1,374
34 Antioxidant Activity of Proteins and Peptides Ryan J. Elias, Sarah S. Kellerby, Eric A. Decker · Critical Reviews in Food Science and Nutrition 4 May 2008 1,350
35 Studies on anticancer activities of antimicrobial peptides David W. Hoskin, Ayyalusamy Ramamoorthy · Biochimica et Biophysica Acta (BBA) - Biomembranes Open access 27 Nov 2007 1,304
36 Microbial α-amylases: a biotechnological perspective Rani Gupta, Paresh Gigras, Harapriya Mohapatra et al. · Process Biochemistry 23 Apr 2003 1,300
37 Fish gelatin: properties, challenges, and prospects as an alternative to mammalian gelatins A. Abd. Karim, Rajeev Bhat · Food Hydrocolloids 7 Jul 2008 1,285
38 Biochemical pathways for the production of flavour compounds in cheeses during ripening: A review Paul L.H. McSweeney, Maria J. Sousa · Le Lait Open access May 2000 1,256
39 PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1) Brigitte A. Rigat, Christine D. Hubert, Pierre Corvol et al. · Nucleic Acids Research Open access 1992 1,252
40 Amphipathic, α-helical antimicrobial peptides Alessandro Tossi, Luca Sandri, Anna Giangaspero · Biopolymers 2000 1,251
41 Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo Prashant Kumar, Jayachandran N. Kizhakkedathu, Suzana K. Straus · Biomolecules Open access 19 Jan 2018 1,242
42 Fish Protein Hydrolysates: Production, Biochemical, and Functional Properties Hörður G. Kristinsson, Barbara A. Rasco · Critical Reviews in Food Science and Nutrition 2000 1,241
43 Recovery of high added-value components from food wastes: Conventional, emerging technologies and commercialized applications Charis M. Galanakis · Trends in Food Science & Technology 21 Mar 2012 1,230
44 Bacteriocin-based strategies for food biopreservation Antonio Gálvez, Hikmate Abriouel, Rosario Lucas López et al. · International Journal of Food Microbiology 14 Jun 2007 1,227
45 A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture Edgar Pick, Yona Keisari · Journal of Immunological Methods Nov 1980 1,225
46 Antioxidant activity of grape seed (Vitis vinifera) extracts on peroxidation models in vitro Guddadarangavvanahally K. Jayaprakasha, Ravendra Pratap Singh, Kunnumpurath K. Sakariah · Food Chemistry May 2001 1,214
47 Probiotic bacteria: safety, functional and technological properties Maria Saarela, Gunnar Mogensen, Rangne Fondén et al. · Journal of Biotechnology Dec 2000 1,199
48 Peptide Antibiotics Robert E. W. Hancock, Daniel S. Chapple · Antimicrobial Agents and Chemotherapy Open access Jun 1999 1,189
49 Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences Earl R. Stadtman · Free Radical Biology and Medicine 1990 1,156
50 Industrial applications of crustacean by-products (chitin, chitosan, and chitooligosaccharides): A review Imen Hamed, Fatih Özoğul, Joe M. Regenstein · Trends in Food Science & Technology 18 Dec 2015 1,137

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.