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Topic · Protein Interaction Studies and Fluorescence Analysis

Most cited papers in Protein Interaction Studies and Fluorescence Analysis

Protein Interaction Studies and Fluorescence Analysis

What are the most cited papers in Protein Interaction Studies and Fluorescence Analysis?

The most cited paper in Protein Interaction Studies and Fluorescence Analysis is "LIGAND: A versatile computerized approach for characterization of ligand-binding systems" (Peter J. Munson, David Rodbard, 1980), with 8,497 citations. Next come "Molecular Properties That Influence the Oral Bioavailability of Drug Candidates" (8,390) and "The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities" (5,614).

Showing 50 of 99 papers. Every paper with more than 877 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 LIGAND: A versatile computerized approach for characterization of ligand-binding systems Peter J. Munson, David Rodbard · Analytical Biochemistry Sep 1980 8,497
2 Molecular Properties That Influence the Oral Bioavailability of Drug Candidates Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry 11 May 2002 8,390
3 The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities Samuel Genheden, Ulf Ryde · Expert Opinion on Drug Discovery Open access 2 Apr 2015 5,614
4 The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes James T. Dodge, Carolyn D. Mitchell, Donald J. Hanahan · Archives of Biochemistry and Biophysics 1963 4,421
5 Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal G. V. R. Born · Nature Jun 1962 4,308
6 Noble Metals on the Nanoscale: Optical and Photothermal Properties and Some Applications in Imaging, Sensing, Biology, and Medicine Prashant K. Jain, Xiaohua Huang, Ivan H. El‐Sayed et al. · Accounts of Chemical Research May 2008 4,199
7 How to measure and predict the molar absorption coefficient of a protein C. Nick Pace, Felix F. Vajdos, Lanette R. Fee et al. · Protein Science Open access Nov 1995 3,948
8 Atomic structure and chemistry of human serum albumin Xiao He, Daniel C. Carter · Nature 16 Jul 1992 3,831
9 Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels Arnold L. Shapiro, Eladio Viñuela, Jacob V. Maizel · Biochemical and Biophysical Research Communications Sep 1967 3,779
10 Shell-isolated nanoparticle-enhanced Raman spectroscopy Jian‐Feng Li, Yi Huang, Yong Ling Ding et al. · Nature 16 Mar 2010 3,551
11 Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles Tommy Cedervall, Iseult Lynch, Stina Lindman et al. · Proceedings of the National Academy of Sciences Open access 2 Feb 2007 3,268
12 Structure of Serum Albumin Daniel C. Carter, Joseph X. Ho · Advances in protein chemistry Book chapter 1994 3,188
13 A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates Nicholas J. Miller, Catherine A Rice-Evans, Michael J. Davies et al. · Clinical Science Apr 1993 3,129
14 Albumin standards and the measurement of serum albumin with bromcresol green Basil T. Doumas, W. Ard Watson, Homer G. Biggs · Clinica Chimica Acta 1971 3,074
15 Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts Martin Lundqvist, Johannes Stigler, Giuliano Elia et al. · Proceedings of the National Academy of Sciences Open access 22 Sep 2008 3,040
16 Examination of the secondary structure of proteins by deconvolved FTIR spectra D. Michael Byler, Heino Susi · Biopolymers Mar 1986 3,000
17 Quenching of fluorescence by oxygen. Probe for structural fluctuations in macromolecules Joseph R. Lakowicz, Gregorio Weber · Biochemistry Open access Oct 1973 2,789
18 Interparticle Coupling Effect on the Surface Plasmon Resonance of Gold Nanoparticles: From Theory to Applications Sujit Kumar Ghosh, Tarasankar Pal · Chemical Reviews Review Nov 2007 2,784
19 Size and Temperature Dependence of the Plasmon Absorption of Colloidal Gold Nanoparticles Stephan Link, Mostafa A. El‐Sayed · The Journal of Physical Chemistry B May 1999 2,781
20 Spectroscopy of Single Hemoglobin Molecules by Surface Enhanced Raman Scattering Hongxing Xu, Erik J. Bjerneld, Mikael Käll et al. · Physical Review Letters 22 Nov 1999 2,366
21 Design and construction of molecular assemblies with large second-order optical nonlinearities. Quantum chemical aspects David R. Kanis, Mark A. Ratner, Tobin Jay Marks · Chemical Reviews 1994 2,327
22 Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology Stefan Tenzer, Dominic Docter, Jörg Kuharev et al. · Nature Nanotechnology 22 Sep 2013 2,259
23 Measurement of two-photon excitation cross sections of molecular fluorophores with data from 690 to 1050 nm Chris Xu, Watt W. Webb · Journal of the Optical Society of America B Mar 1996 2,205
24 Serum Albumin Theodore Peters · Advances in protein chemistry Book chapter 1985 2,180
25 The Stability of Cyclodextrin Complexes in Solution Kenneth A. Connors · Chemical Reviews Review Aug 1997 2,175
26 Stability of Proteins Small Globular Proteins Peter L. Privalov · Advances in protein chemistry Book chapter 1979 2,171
27 Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications L. Harivardhan Reddy, José Luis Arias, Julien Nicolas et al. · Chemical Reviews Review 9 Oct 2012 2,111
28 Gold and Silver Nanoparticles in Sensing and Imaging: Sensitivity of Plasmon Response to Size, Shape, and Metal Composition Kyeong-Seok Lee, Mostafa A. El‐Sayed · The Journal of Physical Chemistry B 6 Sep 2006 2,103
29 Microemulsion-based media as novel drug delivery systems Margaret Jayne Lawrence, Gareth D. Rees · Advanced Drug Delivery Reviews Review Dec 2000 2,043
30 Determination of free amino groups in proteins by trinitrobenzenesulfonic acid Ahmed F.S.A. Habeeb · Analytical Biochemistry Mar 1966 2,043
31 The Use and Misuse of FTIR Spectroscopy in the Determination of Protein Structure Michael Jackson, Henry H. Mantsch · Critical Reviews in Biochemistry and Molecular Biology Review 1995 2,029
32 Human serum albumin: From bench to bedside Gabriella Fanali, Alessandra di Masi, Viviana Trezza et al. · Molecular Aspects of Medicine 30 Dec 2011 1,959
33 Structural Basis of the Drug-binding Specificity of Human Serum Albumin Jamie Ghuman, Patricia A. Zunszain, I. Petitpas et al. · Journal of Molecular Biology 27 Aug 2005 1,939
34 Surface plasmon resonance in gold nanoparticles: a review Vincenzo Amendola, Roberto Pilot, Marco Frasconi et al. · Journal of Physics Condensed Matter 20 Apr 2017 1,931
35 Electromagnetic fields around silver nanoparticles and dimers Encai Hao, George Chappell Schatz · The Journal of Chemical Physics 22 Dec 2003 1,879
36 Critical Evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the Measurement of Nanoparticles and Protein Aggregates Vasco Filipe, Andrea Hawe, Wim Jiskoot · Pharmaceutical Research Open access 3 Mar 2010 1,871
37 Structure and design of polymeric surfactant-based drug delivery systems Vladimir P. Torchilin · Journal of Controlled Release Jun 2001 1,822
38 Shape effects in plasmon resonance of individual colloidal silver nanoparticles Jack J. Mock, Mladen Barbic, David R. Smith et al. · The Journal of Chemical Physics 15 Apr 2002 1,796
39 Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy Parag Aggarwal, Jennifer B. Hall, Christopher B. McLeland et al. · Advanced Drug Delivery Reviews ReviewOpen access 18 Apr 2009 1,788
40 Fluorescence quenching studies with proteins Maurice R. Eftink, Camillo A. Ghiron · Analytical Biochemistry Jul 1981 1,771
41 The Characterization of Two Specific Drug Binding Sites on Human Serum Albumin Gillian Sudlow, D. J. Birkett, DENIS N. WADE · Molecular Pharmacology Nov 1975 1,730
42 Fluorescent Indicators for Intracellular pH Junyan Han, Kevin Burgess · Chemical Reviews Review 16 Oct 2009 1,635
43 Dynamics of ligand binding to myoglobin Robert H. Austin, K. W. Beeson, L. Eisenstein et al. · Biochemistry Dec 1975 1,634
44 On the Universal Scaling Behavior of the Distance Decay of Plasmon Coupling in Metal Nanoparticle Pairs: A Plasmon Ruler Equation Prashant K. Jain, Wenyu Huang, Mostafa A. El‐Sayed · Nano Letters 19 Jun 2007 1,584
45 Using chemical shift perturbation to characterise ligand binding Mike P. Williamson · Progress in Nuclear Magnetic Resonance Spectroscopy 20 Mar 2013 1,539
46 Albumin-based nanoparticles as potential controlled release drug delivery systems Ahmed O. Elzoghby, Wael Mahmoud Samy, Nazik A. Elgindy · Journal of Controlled Release 3 Aug 2011 1,524
47 A graphic method for the determination and presentation of binding parameters in a complex system Hannah E. Rosenthal · Analytical Biochemistry Sep 1967 1,522
48 The interaction of a naphthalene dye with apomyoglobin and apohemoglobin Lubert Stryer · Journal of Molecular Biology Sep 1965 1,504
49 Surface-enhanced resonance Raman spectroscopy of Rhodamine 6G adsorbed on colloidal silver Peter Hildebrandt, Manfred Stockburger · The Journal of Physical Chemistry Nov 1984 1,488
50 Further Characterization of Specific Drug Binding Sites on Human Serum Albumin Gillian Sudlow, D. J. Birkett, DENIS N. WADE · Molecular Pharmacology Nov 1976 1,451

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.