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Topic · Molecular Biology

Protein Interaction Studies and Fluorescence Analysis

Protein Interaction Studies and Fluorescence Analysis is a research topic within Molecular Biology. Science Explorer counts 21k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the structural and functional aspects of protein binding specificity, particularly in human serum albumin. The research encompasses various techniques such as fluorescence spectroscopy, crystallographic analysis, and molecular docking to investigate drug interactions, antioxidant properties, fatty acid binding, and plasma protein binding. The studies provide insights into the molecular mechanisms underlying protein-ligand interactions and their implications for drug development and therapeutic potential.

  • Serum Albumin
  • Protein Binding
  • Fluorescence Spectroscopy
  • Drug Interaction
  • Crystal Structure Analysis
  • Molecular Docking
  • Plasma Protein Binding
  • Antioxidant Properties
  • Fatty Acid Binding
  • Biophysical Studies
Research works
21k
fractional, since 1950
In the world top 10%
2k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-10%
the tick is no change
Largest producer
China
32% of the 10 largest, 2022-now
Protein Interaction Studies and Fluorescence Analysis

Which countries lead Protein Interaction Studies and Fluorescence Analysis research?

By volume, China and India publish the most (522 and 437 works in 2022-now).

By volume, 2022-now

  1. 1 China 522 works
  2. 2 India 437 works
  3. 3 United States 176 works
  4. 4 Iran 114 works
  5. 5 Russia 102 works
  6. 6 Poland 63 works
  7. 7 Türkiye 59 works
  8. 8 Japan 59 works
  9. 9 Saudi Arabia 58 works
  10. 10 Germany 51 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 31.8%India: 26.6%United States: 10.8%Iran: 6.9%6 others listed: 23.9%32%largest
China522 · 31.8%India437 · 26.6%United States176 · 10.8%Iran114 · 6.9%6 others listed392 · 23.9%

Shares of the rows listed above, not of the whole node.

Which institutions lead Protein Interaction Studies and Fluorescence Analysis research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Protein Interaction Studies and Fluorescence Analysis research, followed by Aligarh Muslim University and King Saud University.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 46 works
  2. 2 Aligarh Muslim UniversityIndia 26 works
  3. 3 King Saud UniversitySaudi Arabia 25 works
  4. 4 Nanchang UniversityChina 18 works
  5. 5 Centre National de la Recherche ScientifiqueFrance 14 works
  6. 6 Shahrekord UniversityIran 13 works
  7. 7 Chinese Academy of SciencesChina 13 works
  8. 8 Vellore Institute of Technology UniversityIndia 12 works
  9. 9 Islamic Azad University, TehranIran 12 works
  10. 10 Lomonosov Moscow State UniversityRussia 10 works

Who are the leading researchers in Protein Interaction Studies and Fluorescence Analysis?

The most-cited researchers publishing on Protein Interaction Studies and Fluorescence Analysis include George Davey Smith, Giuseppe Remuzzi and Róbert Langer.

  1. 1 George Davey Smith United Kingdom 435k citations
  2. 2 Giuseppe Remuzzi Italy 328k citations
  3. 3 Róbert Langer United States 303k citations
  4. 4 Marcello A. Tonelli Canada 268k citations
  5. 5 George M. Whitesides United States 267k citations
  6. 6 Ben Zhong Tang China 261k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Protein Interaction Studies and Fluorescence Analysis?

The most cited paper in Protein Interaction Studies and Fluorescence Analysis is "LIGAND: A versatile computerized approach for characterization of ligand-binding systems" (Peter J. Munson, David Rodbard, 1980), with 8,497 citations. Next come "Molecular Properties That Influence the Oral Bioavailability of Drug Candidates" (8,390) and "The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities" (5,614).

Most cited papers
#PaperReleasedCitations
1 LIGAND: A versatile computerized approach for characterization of ligand-binding systems Peter J. Munson, David Rodbard · Analytical Biochemistry Sep 1980 8,497
2 Molecular Properties That Influence the Oral Bioavailability of Drug Candidates Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry 11 May 2002 8,390
3 The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities Samuel Genheden, Ulf Ryde · Expert Opinion on Drug Discovery Open access 2 Apr 2015 5,614
4 The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes James T. Dodge, Carolyn D. Mitchell, Donald J. Hanahan · Archives of Biochemistry and Biophysics 1963 4,421
5 Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal G. V. R. Born · Nature Jun 1962 4,308
All 99 most cited papers, with filters and sorting

Where is Protein Interaction Studies and Fluorescence Analysis research done?

The largest centres of Protein Interaction Studies and Fluorescence Analysis research in 2022-now are Beijing (China), Moscow (Russia), New Delhi (India) and Tehran (Iran). Among places with at least 20 works in it, it is an unusually large share of all research in Aligarh.

Largest cities, 2022-now

  1. 1 BeijingChina 53 works
  2. 2 MoscowRussia 41 works
  3. 3 New DelhiIndia 33 works
  4. 4 TehranIran 31 works
  5. 5 RiyadhSaudi Arabia 31 works
  6. 6 MumbaiIndia 29 works
  7. 7 ShanghaiChina 26 works
  8. 8 AligarhIndia 26 works
  9. 9 KolkataIndia 25 works
  10. 10 NanjingChina 25 works

Where it is the local speciality

  1. AligarhIN · 26.0 works37×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Protein Interaction Studies and Fluorescence Analysis than the world average.

See Protein Interaction Studies and Fluorescence Analysis on the map

Where is the best place to study Protein Interaction Studies and Fluorescence Analysis?

Among universities, judged by research, King Saud University, Northeast Agricultural University and Nanchang University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 16.27%fractional works in this field (log) →share of work in the world top 10% →Northeast Agricultur…Shahrekord UniversityNanchang UniversityKing Saud University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1King Saud UniversitySaudi Arabia 70.216.3%12.8×25 +17.4%
2Northeast Agricultural UniversityChina 60.954.6%15.9×8 +51.9%
3Nanchang UniversityChina 55.120.0%11.8×18 +19.3%
4Shahrekord UniversityIran 52.224.6%123.5×13 +47.0%
5Aligarh Muslim UniversityIndia 49.29.1%43.4×26 -30.3%
6Vellore Institute of Technology UniversityIndia 30.48.4%6.0×12 +67.1%
7University of BelgradeSerbia 29.310.1%7.0×9 +126.3%
8Jamia Millia IslamiaIndia 22.14.5%17.5×9 -32.7%
9Lomonosov Moscow State UniversityRussia 20.81.5%6.2×10 -11.5%
10Islamic Azad University, TehranIran 20.213.6%3.5×12 -45.8%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Protein Interaction Studies and Fluorescence Analysis, country by country

Is Protein Interaction Studies and Fluorescence Analysis research growing?

Output in 2022-2025 was 10% lower than in 2018-2021, peaking in 2013.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Protein Interaction Studies and Fluorescence Analysis as a percentage of every work published that year, 0.0090% in 2024.

still counting0.020%0.040%0.060%Protein Interaction Studies and Fluorescence Analysis0.0081% in 202519801990200020102020

Fractional works of Protein Interaction Studies and Fluorescence Analysis over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Protein Interaction Studies and Fluorescence Analysis10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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