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Most cited papers in Retinal Diseases and Treatments

What are the most cited papers in Retinal Diseases and Treatments?

The most cited paper in Retinal Diseases and Treatments is "Repertoires of Autophagy in the Pathogenesis of Ocular Diseases" (Yujie Li, Qin Li Jiang, Guo-Fan Cao et al., 2015), with 16,339 citations. Next come "The biology of VEGF and its receptors" (9,633) and "Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs" (7,873).

Showing 50 of 100 papers. Every paper with more than 1,140 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Repertoires of Autophagy in the Pathogenesis of Ocular Diseases Yujie Li, Qin Li Jiang, Guo-Fan Cao et al. · Cellular Physiology and Biochemistry Open access 2015 16,339
2 The biology of VEGF and its receptors Napoleone Ferrara, Hans‐Peter Gerber, Jennifer E. LeCouter · Nature Medicine 30 May 2003 9,633
3 Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs Varun Gulshan, Lily Peng, Marc Coram et al. · JAMA 29 Nov 2016 7,873
4 Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040 Yih Chung Tham, Li Xiang, Tien Yin Wong et al. · Ophthalmology 26 Jun 2014 7,211
5 Ranibizumab for Neovascular Age-Related Macular Degeneration Philip J. Rosenfeld, David M. Brown, Jeffrey S. Heier et al. · New England Journal of Medicine Open access 4 Oct 2006 5,931
6 Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis Wan Ling Wong, Xinyi Su, Xiang Li et al. · The Lancet Global Health ReviewOpen access 3 Jan 2014 5,452
7 Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy Stefano De Cillà, Serena Farruggio, Stela Vujosevic et al. · Cellular Physiology and Biochemistry Open access 2017 5,140
8 Global Prevalence and Major Risk Factors of Diabetic Retinopathy Joanne Wen Yee Yau et al. · Diabetes Care Open access 2 Feb 2012 5,033
9 Complement Factor H Polymorphism in Age-Related Macular Degeneration Robert J. Klein, Caroline J. Zeiss, Emily Y. Chew et al. · Science Open access 10 Mar 2005 4,552
10 Ridge-Based Vessel Segmentation in Color Images of the Retina Joes Staal, Michael D. Abràmoff, Meindert Niemeijer et al. · IEEE Transactions on Medical Imaging Apr 2004 4,213
11 Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales C. P. Wilkinson, Frederick L. Ferris, Ronald Klein et al. · Ophthalmology Sep 2003 3,812
12 Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg et al. · New England Journal of Medicine Open access Dec 1994 3,806
13 Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration David M. Brown, Peter K. Kaiser, Mark Michels et al. · New England Journal of Medicine 4 Oct 2006 3,535
14 Reduction of Intraocular Pressure and Glaucoma Progression Anders Heijl · Archives of Ophthalmology Oct 2002 3,356
15 Diabetic retinopathy Ning Cheung, Paul Mitchell, Tien Yin Wong · The Lancet 29 Jun 2010 3,202
16 Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study Yasuo Ohkubo, Hideki Kishikawa, Eiichi Araki et al. · Diabetes Research and Clinical Practice May 1995 3,105
17 The Retinal Pigment Epithelium in Visual Function Olaf Strauß · Physiological Reviews Review 29 Jun 2005 2,859
18 Prevalence of Age-Related Macular Degeneration in the United States The Eye Diseases Prevalence Research Group* · Archives of Ophthalmology Open access Apr 2004 2,760
19 Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration The CATT Research Group · New England Journal of Medicine Open access 28 Apr 2011 2,681
20 Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration Jeffrey S. Heier, David M. Brown, Victor N. Chong et al. · Ophthalmology 17 Oct 2012 2,522
21 Complement Factor H Polymorphism and Age-Related Macular Degeneration Albert O. Edwards, Robert Ritter, Kenneth J. Abel et al. · Science 10 Mar 2005 2,467
22 Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes Daniel Shu Wei Ting et al. · JAMA Open access 12 Dec 2017 2,445
23 Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration Jonathan L. Haines, Michael A. Hauser, Silke Schmidt et al. · Science 10 Mar 2005 2,436
24 Global Prevalence of Diabetic Retinopathy and Projection of Burden through 2045 Zhen Ling Teo, Yih Chung Tham, Marco Yu et al. · Ophthalmology May 2021 2,388
25 The definition and classification of glaucoma in prevalence surveys Paul J. Foster · British Journal of Ophthalmology Open access Feb 2002 2,388
26 Pegaptanib for Neovascular Age-Related Macular Degeneration Evangelos S. Gragoudas, Anthony P. Adamis, Emmett T. Cunningham et al. · New England Journal of Medicine Open access 29 Dec 2004 2,343
27 Systematic Reviews: Identifying relevant studies for systematic reviews Kay Dickersin, Roberta W. Scherer, Carol A. Lefebvre · BMJ ReviewOpen access 12 Nov 1994 2,275
28 Primary open-angle glaucoma Robert Neal Weinreb, Peng Tee Khaw · The Lancet May 2004 2,248
29 Development of the 25-list-item National Eye Institute Visual Function Questionnaire Carol M. Mangione · Archives of Ophthalmology Open access Jul 2001 2,237
30 Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography Richard F. Spaide, Hideki Koizumi, Maria C. Pozonni · American Journal of Ophthalmology 18 Jul 2008 2,213
31 Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study Amanda Adler · BMJ Open access 12 Aug 2000 2,159
32 Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis Albert M. Maguire et al. · New England Journal of Medicine Open access 27 Apr 2008 2,156
33 The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration Stephen Beatty, Hui-Hiang Koh, M. Phil et al. · Survey of Ophthalmology Sep 2000 2,071
34 The multifunctional choroid Debora L. Nickla, Josh Wallman · Progress in Retinal and Eye Research Open access 30 Dec 2009 1,989
35 A common haplotype in the complement regulatory gene factor H ( HF1/CFH ) predisposes individuals to age-related macular degeneration Gregory S. Hageman et al. · Proceedings of the National Academy of Sciences Open access 3 May 2005 1,979
36 An international classification and grading system for age-related maculopathy and age-related macular degeneration Alan C. Bird, Neil M. Bressler, Susan B. Bressler et al. · Survey of Ophthalmology Open access Mar 1995 1,939
37 Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis James W. Bainbridge, Alexander J. Smith, Susie S. Barker et al. · New England Journal of Medicine Open access 27 Apr 2008 1,933
38 Clinical Classification of Age-related Macular Degeneration Frederick L. Ferris, Charles P. Wilkinson, Alan C. Bird et al. · Ophthalmology Open access 16 Jan 2013 1,886
39 Prevalence of Age-related Maculopathy Ronald Klein, Ronald Klein, Kathryn L.P. Linton · Ophthalmology Jun 1992 1,850
40 Optical coherence tomography angiography Richard F. Spaide, James G. Fujimoto, Nadia Khalida Waheed et al. · Progress in Retinal and Eye Research Open access 8 Dec 2017 1,797
41 Age-related macular degeneration Laurence Shen Lim, Paul Mitchell, Johanna M. Seddon et al. · The Lancet May 2012 1,754
42 Müller cells in the healthy and diseased retina Andreas Bringmann, Thomas Pannicke, Jens Grosche et al. · Progress in Retinal and Eye Research Jul 2006 1,748
43 Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration Daniel Francis Martin, Maureen G. Maguire, Stuart L. Fine et al. · Ophthalmology Open access May 2012 1,726
44 The impact of ocular blood flow in glaucoma Josef Flammer, Selim Orgül, Vital Paulino Costa et al. · Progress in Retinal and Eye Research Jul 2002 1,721
45 Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation Warren R. Zipfel, Rebecca M. Williams, Richard H. Christie et al. · Proceedings of the National Academy of Sciences Open access 19 May 2003 1,695
46 Optical Coherence Tomography of the Human Retina Michael R. Hee · Archives of Ophthalmology Mar 1995 1,653
47 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants Lars G. Fritsche et al. · Nature Genetics Open access162 authors 21 Dec 2015 1,645
48 Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices Michael D. Abràmoff, Philip T. Lavin, Michele Birch et al. · npj Digital Medicine Open access 21 Aug 2018 1,635
49 Diabetic Retinopathy David A. Antonetti, Ronald Klein, Thomas W. Gardner · New England Journal of Medicine 28 Mar 2012 1,633
50 Retinal Vascular Layers Imaged by Fluorescein Angiography and Optical Coherence Tomography Angiography Richard F. Spaide, James M. Klancnik, Michael J. Cooney · JAMA Ophthalmology 15 Oct 2014 1,630

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.