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Signaling Pathways in Disease

Signaling Pathways in Disease is a research topic within Molecular Biology. Science Explorer counts 24k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the role of Calcineurin-NFAT signaling in transcriptional regulation, with a particular emphasis on its involvement in cancer progression, cardiac hypertrophy, and inflammatory responses. The cluster also explores the impact of Prolyl Isomerase Pin1, EMMPRIN/CD147, and immunophilins in modulating this signaling pathway.

  • Calcineurin
  • NFAT
  • Transcriptional Regulation
  • Prolyl Isomerase Pin1
  • Cancer Progression
  • Cardiac Hypertrophy
  • Immunophilins
  • EMMPRIN/CD147
  • Peptidyl-Prolyl Isomerases
  • Inflammatory Responses
Research works
24k
fractional, since 1950
In the world top 10%
2.3k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-3%
the tick is no change
Largest producer
China
46% of the 10 largest, 2022-now
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