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Most cited papers in Sperm and Testicular Function

What are the most cited papers in Sperm and Testicular Function?

The most cited paper in Sperm and Testicular Function is "The Physiology of Reproduction" (Marc Legendre, Bernard Jalabert, 1988), with 7,880 citations. Next come "Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte" (3,607) and "World Health Organization reference values for human semen characteristics*‡" (2,857).

Showing 50 of 100 papers. Every paper with more than 899 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The Physiology of Reproduction Marc Legendre, Bernard Jalabert · Annals of Internal Medicine 15 Jul 1988 7,880
2 Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte Gianpiero D. Palermo · The Lancet Jul 1992 3,607
3 World Health Organization reference values for human semen characteristics*‡ Trevor G. Cooper, Elizabeth A. Noonan, Sigrid von Eckardstein et al. · Human Reproduction Update 24 Nov 2009 2,857
4 A unique view on male infertility around the globe Ashok Kumar Agarwal, Aditi A. Mulgund, Alaa Hamada et al. · Reproductive Biology and Endocrinology Open access 25 Apr 2015 2,465
5 Men at risk: occupation and male infertility Paul Claman · Fertility and Sterility Open access Mar 2004 2,392
6 National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys Maya Nina Mascarenhas, Seth Flaxman, Ties Boerma et al. · PLoS Medicine Open access 18 Dec 2012 2,382
7 Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment Héctor Francisco Escobar-Morreale · Nature Reviews Endocrinology Review 23 Mar 2018 2,163
8 American Society of Clinical Oncology Recommendations on Fertility Preservation in Cancer Patients Stephanie J. Lee, Leslie R. Schover, Ann H. Partridge et al. · Journal of Clinical Oncology Open access May 2006 2,060
9 Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group Bart C.J.M. Fauser, Basil C. Tarlatzis, Robert W. Rebar et al. · Fertility and Sterility Open access 9 Dec 2011 2,007
10 Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Richard M. Sharpe, Niels Erik Skakkebæk · The Lancet May 1993 1,868
11 Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics Rajasingam S. Jeyendran, Hans H. Van der Ven, M. Perez‐Pelaez et al. · Reproduction Open access 1984 1,714
12 Native specific activity of glutathione peroxidase (GPx-1), phospholipid hydroperoxide glutathione peroxidase (PHGPx) and glutathione reductase (GR) does not differ between normo- and hypomotile human sperm samples Federica Tramer, Luisa Caponecchia, Paolo Sgrò et al. · International Journal of Andrology Open access Apr 2004 1,686
13 Fertility Preservation for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update Alison Wakoff Loren, Pamela B. Mangu, Lindsay Nohr Beck et al. · Journal of Clinical Oncology Open access 29 May 2013 1,626
14 Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene Jamie W. Foster, Marina A. Dominguez-Steglich, Silvana Guioli et al. · Nature Dec 1994 1,621
15 Capacitation of Bovine Sperm by Heparin1 John J. Parrish, John J. Parrish, Martin A. Winer et al. · Biology of Reproduction Open access Jun 1988 1,598
16 Spermatogenesis following male germ-cell transplantation. Ralph L. Brinster, James W. Zimmermann · Proceedings of the National Academy of Sciences Open access 22 Nov 1994 1,580
17 The causes of reduced fertility with cryopreserved semen P.F. Watson · Animal Reproduction Science Jul 2000 1,567
18 Role of reactive oxygen species in the pathophysiology of human reproduction Ashok Kumar Agarwal, Ramadan Saleh, Mohamed A. Bedaiwy · Fertility and Sterility Open access Apr 2003 1,564
19 Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes Yoshio Masui, Clement L. Markert · Journal of Experimental Zoology Jun 1971 1,559
20 Oxidative stress and male infertility—a clinical perspective Kelton P. Tremellen · Human Reproduction Update Open access 14 Feb 2008 1,520
21 DMY is a Y-specific DM-domain gene required for male development in the medaka fish Masaru Matsuda, Yoshitaka Nagahama, Ai Shinomiya et al. · Nature May 2002 1,510
22 Fertilizing Capacity of Spermatozoa deposited into the Fallopian Tubes M. C. Chang · Nature Oct 1951 1,491
23 Fixation of Ejaculated Spermatozoa for Electron Microscopy Mario Stefanini, Cesare De Martino, Luciano Zamboni · Nature Oct 1967 1,463
24 Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings Philippe Jean Guerin · Human Reproduction Update Open access Mar 2001 1,440
25 Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF Xiaojuan Meng, Maria Lindahl, Mervi E. Hyvönen et al. · Science 25 Feb 2000 1,421
26 Spermatogenic cells of the prepuberal mouse: isolation and morphological characterization AR Bellve, Cavicchia Jc, C.F. Millette et al. · The Journal of Cell Biology Open access Jul 1977 1,414
27 Male reproductive health and environmental xenoestrogens. Jorma Toppari, J. C. Larsen, P. Christiansen et al. · Environmental Health Perspectives Open access Aug 1996 1,408
28 Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility T. Rajendra Kumar, Yan Wang, Naifang Lu et al. · Nature Genetics Feb 1997 1,377
29 Temporal trends in sperm count: a systematic review and meta-regression analysis Hagai Levine, Niels Jørgensen, Anderson Joel Martino‐Andrade et al. · Human Reproduction Update ReviewOpen access 28 Jun 2017 1,375
30 Sperm Morphology, Motility, and Concentration in Fertile and Infertile Men David S. Guzick, James W. Overstreet, Pam Factor-Litvak et al. · New England Journal of Medicine Open access 8 Nov 2001 1,330
31 Sex Determination: Why So Many Ways of Doing It? Doris Bachtrog, Judith E. Mank, Catherine L. Peichel et al. · PLoS Biology Open access Jul 2014 1,329
32 Demethylation of the zygotic paternal genome Wolfgang Mayer, Alain Niveleau, Jörn Walter et al. · Nature Feb 2000 1,323
33 Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11 Peter H. VOGT · Human Molecular Genetics Jul 1996 1,319
34 Effect of Oxidative Stress on Male Reproduction Ashok Kumar Agarwal, Gurpriya Virk, Chloe Shu Hui Ong et al. · The World Journal of Men s Health Open access 2014 1,301
35 Ovarian Aging: Mechanisms and Clinical Consequences Frank J. Broekmans, Michael R. Soules, Bart C.J.M. Fauser · Endocrine Reviews 9 Jul 2009 1,281
36 Male infertility Ashok Kumar Agarwal, Saradha Baskaran, Neel V. Parekh et al. · The Lancet 10 Dec 2020 1,269
37 Highly efficient vitrification method for cryopreservation of human oocytes Masashige Kuwayama, Gábor Vajta, Osamu Kato et al. · Reproductive BioMedicine Online Open access 2005 1,268
38 In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells Laura K. Braydich‐Stolle, Saber M. Hussain, John J. Schlager et al. · Toxicological Sciences Open access 13 Jul 2005 1,249
39 Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood RM Sharpe, Chris McKinnell, C Kivlin et al. · Reproduction Jun 2003 1,249
40 Generation of Reactive Oxygen Species, Lipid Peroxidation, and Human Sperm Function R. John Aitken, Jane S. Clarkson, Simon B. Fishel · Biology of Reproduction Jul 1989 1,235
41 Sperm morphologic features as a prognostic factor in in vitro fertilization Thinus Frans Kruger, Roelof Menkveld, Frik S.H. Stander et al. · Fertility and Sterility Open access Dec 1986 1,222
42 Spermatogenesis in fish Rüdiger W. Schulz, Luiz R. França, Jean‐Jacques Lareyre et al. · General and Comparative Endocrinology 7 Apr 2009 1,209
43 A large focus of naturally acquired Plasmodium knowlesi infections in human beings Balbir Bagicha Singh, Lee Kim Sung, Asmad Matusop et al. · The Lancet Mar 2004 1,207
44 Bovine in vitro fertilization with frozen-thawed semen John J. Parrish, J.L. Susko-Parrish, M.L. Leibfried-Rutledge et al. · Theriogenology Apr 1986 1,190
45 Predictive value of abnormal sperm morphology in in vitro fertilization Thinus Frans Kruger, Anı́bal A. Acosta, Kathryn F. Simmons et al. · Fertility and Sterility Open access 1988 1,169
46 Capacitation of Rabbit Spermatozoa in vitro Benjamin Gaylord Brackett, Gene Oliphant · Biology of Reproduction Mar 1975 1,153
47 Decline in Semen Quality among Fertile Men in Paris during the Past 20 Years Jacques Auger, Jean Marie Kunstmann, F Czyglik et al. · New England Journal of Medicine Open access 2 Feb 1995 1,137
48 Trends of male factor infertility, an important cause of infertility: A review of literature Naina Kumar, Amit Kant Singh · Journal of Human Reproductive Sciences Open access Oct 2015 1,136
49 Advances in Male Contraception Stephanie T. Page, John Kenneth Amory, William J. Bremner · Endocrine Reviews Open access 24 Apr 2008 1,135
50 Sperm transport in the female reproductive tract Susan S. Suárez, Allan Anthony Pacey · Human Reproduction Update Open access 4 Nov 2005 1,127

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.