Most cited papers in Steroid Chemistry and Biochemistry
What are the most cited papers in Steroid Chemistry and Biochemistry?
The most cited paper in Steroid Chemistry and Biochemistry is "Enzymatic Determination of Total Serum Cholesterol" (Charles C. Allain, Lucy S Poon, Cicely S G Chan et al., 1974), with 9,199 citations. Next come "Molecular basis of agonism and antagonism in the oestrogen receptor" (3,370) and "Cyclooxygenases: Structural, Cellular, and Molecular Biology" (2,933).
Showing 50 of 100 papers. Every paper with more than 422 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Enzymatic Determination of Total Serum Cholesterol Charles C. Allain, Lucy S Poon, Cicely S G Chan et al. · Clinical Chemistry | Apr 1974 | 9,199 |
| 2 | Molecular basis of agonism and antagonism in the oestrogen receptor Andrzej Marek Brzozowski, Ashley C. W. Pike, Zbigniew Dauter et al. · Nature | Oct 1997 | 3,370 |
| 3 | Cyclooxygenases: Structural, Cellular, and Molecular Biology William Lee Smith, David L. DeWitt, R. Michael Garavito · Annual Review of Biochemistry | Jun 2000 | 2,933 |
| 4 | Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily Sergio A. Oñate, Sophia Y. Tsai, Ming‐Jer Tsai et al. · Science | 24 Nov 1995 | 2,418 |
| 5 | Drug Discovery and Natural Products: End of an Era or an Endless Frontier? Jesse W.-H. Li, John C. Vederas · Science | 9 Jul 2009 | 2,077 |
| 6 | Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor Jeffrey L. Arriza, Cary Weinberger, Gail Cerelli et al. · Science | 17 Jul 1987 | 1,973 |
| 7 | Primary structure and expression of a functional human glucocorticoid receptor cDNA Stanley M. Hollenberg, Cary Weinberger, Estelita S. Ong et al. · Nature | Dec 1985 | 1,881 |
| 8 | Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition Daniel L. Simmons, Regina M. Botting, Timothy Hla · Pharmacological Reviews | 18 Aug 2004 | 1,694 |
| 9 | A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension Richard P. Lifton, Robert G. Dluhy, Michael D. Powers et al. · Nature | 1992 | 1,169 |
| 10 | Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses Robert A. Moreau, Bruce D. Whitaker, Kevin B. Hicks · Progress in Lipid Research | 26 Aug 2002 | 1,166 |
| 11 | A potent specific pure antiestrogen with clinical potential. A. E. Wakeling, Michael Dukes, Jean Bowler · PubMed | Aug 1991 | 1,108 |
| 12 | Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues Ian E. Bush · Biochemical Journal | 1952 | 1,033 |
| 13 | The Conversion of Testosterone to 5α-Androstan-17β-ol-3-one by Rat Prostate in Vivo and in Vitro Nicholas Bruchovsky, Jean D. Wilson · Journal of Biological Chemistry | Apr 1968 | 1,026 |
| 14 | Regulation of the Acute Production of Steroids in Steroidogenic Cells* Douglas M. Stocco, Barbara J. Clark · Endocrine Reviews | Jun 1996 | 1,015 |
| 15 | Microbial drug discovery: 80 years of progress Arnold L. Demain, Sergio García Sánchez · The Journal of Antibiotics | 2009 | 1,006 |
| 16 | Structure of the ligand‐binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist Ashley C. W. Pike, Andrzej M. Brzozowski, Roderick E. Hubbard et al. · The EMBO Journal | Sep 1999 | 981 |
| 17 | Thin‐layer chromatography of lipids Helmut K. Mangold · Journal of the American Oil Chemists Society | Dec 1961 | 926 |
| 18 | Cytochromes P450 as versatile biocatalysts Rita Bernhardt · Journal of Biotechnology | 4 Mar 2006 | 893 |
| 19 | A chemical method for the determination of oestriol, oestrone and oestradiol in human urine J. B. Brown · Biochemical Journal | Jun 1955 | 854 |
| 20 | Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition Randy K. Bledsoe, Valerie G. Montana, Thomas Blaine Stanley et al. · Cell | Jul 2002 | 829 |
| 21 | Steroid Receptor Family: Structure and Functions MARY ANNE CARSON-JURICA, William T. Schrader, Bert W. O’Malley · Endocrine Reviews | May 1990 | 825 |
| 22 | Virtual and biomolecular screening converge on a selective agonist for GPR30 Cristian Bologa, Chetana M. Revankar, Susan M. Young et al. · Nature Chemical Biology | 5 Mar 2006 | 820 |
| 23 | Crystal Structure of the Catalytic Domains of Adenylyl Cyclase in a Complex with G sα ·GTPγS John J. G. Tesmer, Roger K. Sunahara, Alfred G. Gilman et al. · Science | 12 Dec 1997 | 816 |
| 24 | STEROID-PROTEIN CONJUGATES Bernard F. Erlanger, Felix Borek, Sam M. Beiser et al. · Journal of Biological Chemistry | Oct 1957 | 791 |
| 25 | THE DETERMINATION OF 17, 21-DIHYDROXY-20-KETOSTEROIDS IN URINE AND PLASMA ROBERT H. SILBER, Curt Culwell Porter · Journal of Biological Chemistry | Oct 1954 | 790 |
| 26 | Evolution of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Cyclooxygenase (COX) Inhibition and Beyond Praveen P. N. Rao, Edward E. Knaus · Journal of Pharmacy & Pharmaceutical Sciences | 20 Sep 2008 | 776 |
| 27 | Cytochrome P450 systems—biological variations of electron transport chains Frank Hannemann, Andreas Bichet, Kerstin Maria Ewen et al. · Biochimica et Biophysica Acta (BBA) - General Subjects | 3 Aug 2006 | 770 |
| 28 | Quantitative isolation and gas–liquid chromatographic analysis of total dietary and fecal neutral steroids Tatu A. Miettinen, EDWARD H. AHRENS, Scott M. Grundy · Journal of Lipid Research | Jul 1965 | 759 |
| 29 | The isoprene rule and the biogenesis of terpenic compounds L. Růžička · Cellular and Molecular Life Sciences | Oct 1953 | 739 |
| 30 | Enzymatische Bestimmung des Gesamt-Cholesterins im Serum Peter Röschlau, Erich Bernt, Wolfgang Gruber · Clinical Chemistry and Laboratory Medicine (CCLM) | 1974 | 737 |
| 31 | Role of Pharmacokinetics and Metabolism in Drug Discovery and Development J H Lin, Anthony Y.H. Lu · Pharmacological Reviews | Dec 1997 | 712 |
| 32 | Multiple and cooperative trans-activation domains of the human glucocorticoid receptor Stanley M. Hollenberg, Ronald M. Evans · Cell | Dec 1988 | 703 |
| 33 | DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity Sebastiaan H. Meijsing, Miles A. Pufall, Alex Yick‐Lun So et al. · Science | 16 Apr 2009 | 695 |
| 34 | The production of fine chemicals by biotransformations Adrie J. J. Straathof, Sven Panke, Andreas B. Schmid · Current Opinion in Biotechnology | Dec 2002 | 692 |
| 35 | Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells Richard J. Pietras, Clara M. Szego · Nature | 6 Jan 1977 | 691 |
| 36 | Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Susan M. Aronica, W. Lee Kraus, Benita S. Katzenellenbogen · Proceedings of the National Academy of Sciences | 30 Aug 1994 | 681 |
| 37 | cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain Erik G. Lund, Joseph Manuel Guileyardo, David W. Russell · Proceedings of the National Academy of Sciences | 22 Jun 1999 | 665 |
| 38 | Congenital adrenal hyperplasia Diala El-Maouche, Wiebke Arlt, Deborah P Merke · The Lancet | 31 May 2017 | 652 |
| 39 | Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori J. C. Atherton, Richard M. Peek, KT Tham et al. · Gastroenterology | 1997 | 652 |
| 40 | Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis Mats Hámberg, Bengt O. Samuelsson · Proceedings of the National Academy of Sciences | Mar 1973 | 645 |
| 41 | Biosynthesis of Cholesterol and Other Sterols W. David Nes · Chemical Reviews | 8 Sep 2011 | 644 |
| 42 | The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse Michael P. McLeod et al. · Proceedings of the National Academy of Sciences | 9 Oct 2006 | 643 |
| 43 | Phytosterols as Anticancer Dietary Components: Evidence and Mechanism of Action Atif B. Awad, Carol S. Fink · Journal of Nutrition | Sep 2000 | 642 |
| 44 | P HYTOSTEROLS IN H UMAN N UTRITION Richard E. Ostlund · Annual Review of Nutrition | Jul 2002 | 628 |
| 45 | Evolution of Hormone-Receptor Complexity by Molecular Exploitation Jamie T. Bridgham, Sean Michael Carroll, Joseph W. Thornton · Science | 6 Apr 2006 | 622 |
| 46 | Why there are two cyclooxygenase isozymes William Lee Smith, Robert J. Langenbach · Journal of Clinical Investigation | 15 Jun 2001 | 619 |
| 47 | Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2 Christine Luong, Aaron B. Miller, Jim W. Barnett et al. · Nature Structural Biology | Nov 1996 | 618 |
| 48 | Cytochrome P450 and the Individuality of Species David R. Nelson · Archives of Biochemistry and Biophysics | Sep 1999 | 616 |
| 49 | Enzymology of human cytosolic sulfotransferases Charles Napoleon Falany · The FASEB Journal | Mar 1997 | 609 |
| 50 | Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. David L. DeWitt, William Lee Smith · Proceedings of the National Academy of Sciences | Mar 1988 | 599 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.