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Steroid Chemistry and Biochemistry

Steroid Chemistry and Biochemistry is a research topic within Molecular Biology. Science Explorer counts 12k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the microbial transformation and degradation of steroids, particularly cholesterol, by various microorganisms such as Mycobacterium tuberculosis and actinobacteria. It explores the enzymatic processes involved in steroid metabolism, including the role of cholesterol oxidase and 3-ketosteroid dehydrogenases. The cluster also delves into the biotechnological applications and potential biotransformation of steroids for drug development.

  • Microbial Transformation
  • Steroid Degradation
  • Cholesterol Oxidase
  • Biotransformation
  • Mycobacterium tuberculosis
  • 3-Ketosteroid Dehydrogenase
  • Actinobacteria
  • Enzymatic Hydroxylation
  • Rhodococcus erythropolis
  • Metagenomes
Research works
12k
fractional, since 1950
In the world top 10%
1.2k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+7%
the tick is no change
Largest producer
China
40% of the 10 largest, 2022-now
Steroid Chemistry and Biochemistry

Which countries lead Steroid Chemistry and Biochemistry research?

By volume, China and the United States publish the most (228 and 111 works in 2022-now).

By volume, 2022-now

  1. 1 China 228 works
  2. 2 United States 111 works
  3. 3 India 55 works
  4. 4 Russia 43 works
  5. 5 Germany 39 works
  6. 6 Japan 22 works
  7. 7 France 19 works
  8. 8 Spain 17 works
  9. 9 United Kingdom 17 works
  10. 10 Brazil 14 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 40.3%United States: 19.7%India: 9.7%Russia: 7.6%6 others listed: 22.6%40%largest
China228 · 40.3%United States111 · 19.7%India55 · 9.7%Russia43 · 7.6%6 others listed128 · 22.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Steroid Chemistry and Biochemistry research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Steroid Chemistry and Biochemistry research, followed by Chinese Academy of Sciences and Jiangnan University.

Who are the leading researchers in Steroid Chemistry and Biochemistry?

The most-cited researchers publishing on Steroid Chemistry and Biochemistry include Scott M. Grundy, Peter John Barnes and George M. Sheldrick.

  1. 1 Scott M. Grundy United States 257k citations
  2. 2 Peter John Barnes United Kingdom 225k citations
  3. 3 George M. Sheldrick Germany 220k citations
  4. 4 Bruce S. McEwen United States 216k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Steroid Chemistry and Biochemistry?

The most cited paper in Steroid Chemistry and Biochemistry is "Enzymatic Determination of Total Serum Cholesterol" (Charles C. Allain, Lucy S Poon, Cicely S G Chan et al., 1974), with 9,199 citations. Next come "Molecular basis of agonism and antagonism in the oestrogen receptor" (3,370) and "Cyclooxygenases: Structural, Cellular, and Molecular Biology" (2,933).

Most cited papers
#PaperReleasedCitations
1 Enzymatic Determination of Total Serum Cholesterol Charles C. Allain, Lucy S Poon, Cicely S G Chan et al. · Clinical Chemistry Open access Apr 1974 9,199
2 Molecular basis of agonism and antagonism in the oestrogen receptor Andrzej Marek Brzozowski, Ashley C. W. Pike, Zbigniew Dauter et al. · Nature Oct 1997 3,370
3 Cyclooxygenases: Structural, Cellular, and Molecular Biology William Lee Smith, David L. DeWitt, R. Michael Garavito · Annual Review of Biochemistry Review Jun 2000 2,933
4 Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily Sergio A. Oñate, Sophia Y. Tsai, Ming‐Jer Tsai et al. · Science 24 Nov 1995 2,418
5 Drug Discovery and Natural Products: End of an Era or an Endless Frontier? Jesse W.-H. Li, John C. Vederas · Science 9 Jul 2009 2,077
All 100 most cited papers, with filters and sorting

Where is Steroid Chemistry and Biochemistry research done?

The largest centres of Steroid Chemistry and Biochemistry research in 2022-now are Beijing (China), Shanghai (China), Moscow (Russia) and Wuhan (China).

Largest cities, 2022-now

  1. 1 BeijingChina 27 works
  2. 2 ShanghaiChina 19 works
  3. 3 MoscowRussia 16 works
  4. 4 WuhanChina 16 works
  5. 5 HangzhouChina 15 works
  6. 6 TianjinChina 13 works
  7. 7 WuxiChina 13 works
  8. 8 PushchinoRussia 11 works
  9. 9 NanjingChina 9 works
  10. 10 GuangzhouChina 9 works
See Steroid Chemistry and Biochemistry on the map

Where is the best place to study Steroid Chemistry and Biochemistry?

Among universities, judged by research, Jiangnan University and Zhejiang University of Technology score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Jiangnan UniversityChina 80.033.3%29.3×12 +79.0%
2Zhejiang University of TechnologyChina 10.011.0%23.6×9 +235.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Steroid Chemistry and Biochemistry, country by country

Is Steroid Chemistry and Biochemistry research growing?

Output in 2022-2025 was 7% higher than in 2018-2021, peaking in 2012. The fastest-growing topics are Steroid Chemistry and Biochemistry.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Steroid Chemistry and Biochemistry as a percentage of every work published that year, 0.0030% in 2024.

still counting0.025%0.050%0.075%Steroid Chemistry and Biochemistry0.0033% in 202519801990200020102020

Fractional works of Steroid Chemistry and Biochemistry over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Steroid Chemistry and Biochemistry10.7% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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