Most cited papers in Synthesis of heterocyclic compounds
What are the most cited papers in Synthesis of heterocyclic compounds?
The most cited paper in Synthesis of heterocyclic compounds is "Neuroactive steroids" (Steven M. Paul, Robert H. Purdy, 1992), with 1,329 citations. Next come "Biological Activities of Hydrazone Derivatives" (1,221) and "Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea" (1,055).
Showing 50 of 100 papers. Every paper with more than 259 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Neuroactive steroids Steven M. Paul, Robert H. Purdy · The FASEB Journal | Mar 1992 | 1,329 |
| 2 | Biological Activities of Hydrazone Derivatives Sevım Rollas, Şükriye Güniz Küçükgüzel · Molecules | 17 Aug 2007 | 1,221 |
| 3 | Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea Tomotaka Okino, Yasutaka Hoashi, Tomihiro Furukawa et al. · Journal of the American Chemical Society | 3 Dec 2004 | 1,055 |
| 4 | Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts Benedek Vakulya, Szilárd Varga, Antal Csámpai et al. · Organic Letters | 14 Apr 2005 | 984 |
| 5 | Imidazolylidenes, imidazolinylidenes and imidazolidines Anthony J. Arduengo, Roland Krafczyk, Reinhard Schmutzler et al. · Tetrahedron | Dec 1999 | 957 |
| 6 | 1,3-Dimethyl-4-imidazolinyliden-(2)-pentacarbonylchrom ein neuer übergangsmetall-carben-komplex Karl Öfele · Journal of Organometallic Chemistry | Jun 1968 | 865 |
| 7 | Heterocyclen aus CH‐aciden Nitrilen, VIII. 2‐Amino‐thiophene aus methylenaktiven Nitrilen, Carbonylverbindungen und Schwefel KARL GEWALD, Elfriede Schinke, Horst Böttcher · Chemische Berichte | 1966 | 781 |
| 8 | Quinolines and structurally related heterocycles as antimalarials Kirandeep Kaur, Meenakshi Jain, Ravi P. Reddy et al. · European Journal of Medicinal Chemistry | 19 Apr 2010 | 728 |
| 9 | De novo synthesis of substituted pyridines Gavin D. Henry · Tetrahedron | 11 May 2004 | 709 |
| 10 | Thionation reactions of lawesson's reagents Michael P. Cava, Matthew I. Levinson · Tetrahedron | 1985 | 665 |
| 11 | Synthesis of Imidazol-2-ylidenes by Reduction of Imidazole-2(3H)-thiones Norbert Kühn, Thomas Kratz · Synthesis | 1993 | 657 |
| 12 | Synthesis and Biological Activity of α‐Methylene‐γ‐butyrolactones H. M. R. Hoffmann, Jürgen P. Rabe · Angewandte Chemie International Edition in English | Feb 1985 | 653 |
| 13 | A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry Rangappa Sangappa Keri, Mahadeo R. Patil, Siddappa A. Patil et al. · European Journal of Medicinal Chemistry | 21 Oct 2014 | 632 |
| 14 | Chondrocyte apoptosis induced by nitric oxide. Francisco Javier Blanco, Robert Ochs, Herbert S. Schwarz et al. · PubMed | 1995 | 627 |
| 15 | Heterocycles in Medicinal Chemistry Josef Jampílek · Molecules | 25 Oct 2019 | 620 |
| 16 | Catalyzed Addition of Aldehydes to Activated Double Bonds—A New Synthetic Approach Hermann Stetter · Angewandte Chemie International Edition in English | Nov 1976 | 617 |
| 17 | Transfer of Sulfur: From Simple to Diverse Hui Liu, Xuefeng Jiang · Chemistry - An Asian Journal | 11 Jul 2013 | 612 |
| 18 | Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions Fabio Bellina, Renzo Rossi · Tetrahedron | 16 Jun 2006 | 606 |
| 19 | o-Quinone methides: intermediates underdeveloped and underutilized in organic synthesis Ryan W. Van De Water, Thomas R. R. Pettus · Tetrahedron | Jul 2002 | 585 |
| 20 | Transition-metal mediated carbon–sulfur bond activation and transformations Liandi Wang, Wei He, Zhengkun Yu · Chemical Society Reviews | 18 Oct 2012 | 585 |
| 21 | Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions Paul Jackson, John C. Widen, Daniel A. Harki et al. · Journal of Medicinal Chemistry | 20 Dec 2016 | 575 |
| 22 | Metal-Free Multicomponent Syntheses of Pyridines Christophe Allais, Jean‐Marie Grassot, Jean Rodríguez et al. · Chemical Reviews | 10 Oct 2014 | 518 |
| 23 | Advances in the Baylis–Hillman reaction-assisted synthesis of cyclic frameworks Vijay Singh, Sanjay Batra · Tetrahedron | 3 Mar 2008 | 515 |
| 24 | Evidence for Intramolecular N−H···O Resonance-Assisted Hydrogen Bonding in β-Enaminones and Related Heterodienes. A Combined Crystal-Structural, IR and NMR Spectroscopic, and Quantum-Mechanical Investigation P. Gilli, Valerio Bertolasi, V. Ferretti et al. · Journal of the American Chemical Society | Oct 2000 | 515 |
| 25 | Synthesis of Heterocycles from Alkyl 3-(Dimethylamino)propenoates and Related Enaminones Branko Stanovnik, Jurij Svete · Chemical Reviews | 13 Feb 2004 | 507 |
| 26 | Use of Lawesson's Reagent in Organic Syntheses Turan Öztürk, Erdal Ertaş, Olcay Mert · Chemical Reviews | 15 Sep 2007 | 501 |
| 27 | Thioamides as Useful Synthons in the Synthesis of Heterocycles Tadeusz Stefan Jagodziński · Chemical Reviews | 3 Dec 2002 | 486 |
| 28 | 4‐Aryldihydropyridines, a New Class of Highly Active Calcium Antagonists Friedrich Bossert, Horst Meyer, E Wehinger · Angewandte Chemie International Edition in English | Sep 1981 | 486 |
| 29 | The Baylis–Hillman reaction: a novel source of attraction, opportunities, and challenges in synthetic chemistry Deevi Basavaiah, Kalapala Venkateswara Rao, Raju Jannapu Reddy · Chemical Society Reviews | 2007 | 472 |
| 30 | Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action. Kelvin W. Gee, Michael B. Bolger, Roberta Dı́az Brinton et al. · Journal of Pharmacology and Experimental Therapeutics | Aug 1988 | 468 |
| 31 | Recent developments and biological activities of thiazolidinone derivatives: A review Abhishek Kumar Jain, Ankur Vaidya, Veerasamy Ravichandran et al. · Bioorganic & Medicinal Chemistry | 13 Apr 2012 | 463 |
| 32 | Quinoline: A versatile heterocyclic Akranth Marella, Omprakash Tanwar, Rikta Saha et al. · Saudi Pharmaceutical Journal | 29 Mar 2012 | 458 |
| 33 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes Dalip Kumar, V. Buchi Reddy, Shashwat Sharad et al. · European Journal of Medicinal Chemistry | 17 Apr 2009 | 458 |
| 34 | A Reexamination of the Mechanism of the Biginelli Dihydropyrimidine Synthesis. Support for an N-Acyliminium Ion Intermediate1 Christian Oliver Kappe · The Journal of Organic Chemistry | Oct 1997 | 454 |
| 35 | N,N-Dimethylformamide: much more than a solvent Jacques Мuzart · Tetrahedron | 28 Jun 2009 | 454 |
| 36 | Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents George C. Rovnyak, Karnail S. Atwal, Anders Hedberg et al. · Journal of Medicinal Chemistry | Aug 1992 | 451 |
| 37 | A review exploring biological activities of hydrazones Mohammad Mumtaz Alam, Garima Verma, Akranth Marella et al. · Journal of Pharmacy And Bioallied Sciences | 2014 | 443 |
| 38 | Recently reported biological activities of pyrazole compounds Jéssica Venância Faria, Percilene Fazolin Vegi, Ana Gabriella Carvalho Miguita et al. · Bioorganic & Medicinal Chemistry | 23 Sep 2017 | 439 |
| 39 | Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents Sohail Saeed, Naghmana Rashid, Peter G. Jones et al. · European Journal of Medicinal Chemistry | 17 Dec 2009 | 434 |
| 40 | Design, synthesis and biological evaluation of some pyrazole derivatives as anti-inflammatory-antimicrobial agents Adnan A. Bekhit, Tarek Abdel-Aziem · Bioorganic & Medicinal Chemistry | 6 Mar 2004 | 434 |
| 41 | Synthesis and reactions of 1,1-diamino-2,2-dinitroethylene N.V. Latypov, Jan Bergman, Abraham Langlét et al. · Tetrahedron | Sep 1998 | 431 |
| 42 | Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities Mohamed Abdel‐Aziz, Gamal El‐Din A. Abuo‐Rahma, Alaa A. Hassan · European Journal of Medicinal Chemistry | 10 Feb 2009 | 409 |
| 43 | Recent Advances in Organic Reactions Involving Elemental Sulfur Thanh Bình Nguyễn · Advanced Synthesis & Catalysis | 2 Mar 2017 | 401 |
| 44 | On the Question of Stability, Conjugation, and “Aromaticity” in Imidazol-2-ylidenes and Their Silicon Analogs Christoph Heinemann, Thomas Müller, Yitzhak Apeloig et al. · Journal of the American Chemical Society | 1996 | 390 |
| 45 | A direct synthesis of olefins by reaction of carbonyl compounds with lithio derivatives of 2-[alkyl- or (2′-alkenyl)- or benzyl-sulfonyl]-benzothiazoles. J.‐B. BAUDIN, Georges P.-J. Hareau, Sylvestre A. Julia et al. · Tetrahedron Letters | Feb 1991 | 386 |
| 46 | Dihydropyrimidine calcium channel blockers. II. 3-Substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines Karnail S. Atwal, George C. Rovnyak, S. David Kimball et al. · Journal of Medicinal Chemistry | Sep 1990 | 378 |
| 47 | Bioactive thiazole and benzothiazole derivatives Abdul Rouf, Cihangir Tanyeli · European Journal of Medicinal Chemistry | 22 Oct 2014 | 377 |
| 48 | Beyond the Pummerer Reaction: Recent Developments in Thionium Ion Chemistry Laura H. S. Smith, S. C. Coote, Helen F. Sneddon et al. · Angewandte Chemie International Edition | 25 Jun 2010 | 376 |
| 49 | Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring Sanjay Kumar Bharti, Gopal Nath, Ragini Tilak et al. · European Journal of Medicinal Chemistry | 8 Nov 2009 | 375 |
| 50 | Synthesis, Antimicrobial and Antifungal Activity of a New Class of Spiro pyrrolidines Ambrose Amal Raj, R. Raghunathan, M.R SrideviKumari et al. · Bioorganic & Medicinal Chemistry | Feb 2003 | 371 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.