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Topic · Organic Chemistry

Synthesis of heterocyclic compounds

Synthesis of heterocyclic compounds is a research topic within Organic Chemistry. Science Explorer counts 19k research works in it since 1950. 10.0% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on recent developments in ketene dithioacetal chemistry, showcasing various synthetic strategies for the regioselective synthesis of highly functionalized heterocycles and other compounds. The research covers topics such as annulation, catalyzed reactions, and multicomponent reactions to produce diverse and functionalized compounds including thiophenes and pyridinones.

  • Ketene Dithioacetal
  • Annulation
  • Synthesis
  • Heterocycles
  • Regioselective
  • Catalyzed Reactions
  • Functionalized Compounds
  • Multicomponent Reaction
  • Thiophenes
  • Pyridinones
Research works
19k
fractional, since 1950
In the world top 10%
1.9k
per year above
Top-10% rate
10.0%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-11%
the tick is no change
Largest producer
India
29% of the 10 largest, 2022-now
Synthesis of heterocyclic compounds

Which countries lead Synthesis of heterocyclic compounds research?

By volume, India and China publish the most (233 and 198 works in 2022-now).

By volume, 2022-now

  1. 1 India 233 works
  2. 2 China 198 works
  3. 3 Russia 150 works
  4. 4 United States 48 works
  5. 5 Egypt 42 works
  6. 6 Iran 35 works
  7. 7 Saudi Arabia 29 works
  8. 8 Japan 24 works
  9. 9 Germany 22 works
  10. 10 Türkiye 21 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

India: 29.1%China: 24.7%Russia: 18.7%United States: 6.0%6 others listed: 21.6%29%largest
India233 · 29.1%China198 · 24.7%Russia150 · 18.7%United States48 · 6.0%6 others listed173 · 21.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Synthesis of heterocyclic compounds research?

By volume in 2022-now, Russian Academy of Sciences publishes the most Synthesis of heterocyclic compounds research, followed by Institute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical Chemistry and University of Mysore.

By volume, 2022-now

  1. 1 Russian Academy of SciencesRussia 54 works
  2. 2 Institute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical ChemistryArmenia 8 works
  3. 3 University of MysoreIndia 8 works
  4. 4 Banaras Hindu UniversityIndia 8 works
  5. 5 Ural Federal UniversityRussia 8 works
  6. 6 Centre National de la Recherche ScientifiqueFrance 8 works
  7. 7 Chinese Academy of SciencesChina 7 works
  8. 8 Cairo UniversityEgypt 7 works
  9. 9 Council of Scientific and Industrial ResearchIndia 7 works
  10. 10 Lomonosov Moscow State UniversityRussia 6 works

Who are the leading researchers in Synthesis of heterocyclic compounds?

The most-cited researchers publishing on Synthesis of heterocyclic compounds include Richard A. Gibbs, George M. Sheldrick and Seeram Ramakrishna.

  1. 1 Richard A. Gibbs United States 292k citations
  2. 2 George M. Sheldrick Germany 220k citations
  3. 3 Seeram Ramakrishna Singapore 186k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Synthesis of heterocyclic compounds?

The most cited paper in Synthesis of heterocyclic compounds is "Neuroactive steroids" (Steven M. Paul, Robert H. Purdy, 1992), with 1,329 citations. Next come "Biological Activities of Hydrazone Derivatives" (1,221) and "Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea" (1,055).

Most cited papers
#PaperReleasedCitations
1 Neuroactive steroids Steven M. Paul, Robert H. Purdy · The FASEB Journal Mar 1992 1,329
2 Biological Activities of Hydrazone Derivatives Sevım Rollas, Şükriye Güniz Küçükgüzel · Molecules Open access 17 Aug 2007 1,221
3 Enantio- and Diastereoselective Michael Reaction of 1,3-Dicarbonyl Compounds to Nitroolefins Catalyzed by a Bifunctional Thiourea Tomotaka Okino, Yasutaka Hoashi, Tomihiro Furukawa et al. · Journal of the American Chemical Society 3 Dec 2004 1,055
4 Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts Benedek Vakulya, Szilárd Varga, Antal Csámpai et al. · Organic Letters 14 Apr 2005 984
5 Imidazolylidenes, imidazolinylidenes and imidazolidines Anthony J. Arduengo, Roland Krafczyk, Reinhard Schmutzler et al. · Tetrahedron Dec 1999 957
All 100 most cited papers, with filters and sorting

Where is Synthesis of heterocyclic compounds research done?

The largest centres of Synthesis of heterocyclic compounds research in 2022-now are Moscow (Russia), Beijing (China), Yekaterinburg (Russia) and Yerevan (Armenia).

Largest cities, 2022-now

  1. 1 MoscowRussia 44 works
  2. 2 BeijingChina 16 works
  3. 3 YekaterinburgRussia 14 works
  4. 4 YerevanArmenia 14 works
  5. 5 GizaEgypt 12 works
  6. 6 TehranIran 12 works
  7. 7 Saint PetersburgRussia 11 works
  8. 8 New DelhiIndia 11 works
  9. 9 CairoEgypt 11 works
  10. 10 PermRussia 11 works
See Synthesis of heterocyclic compounds on the map

Where is the best place to study Synthesis of heterocyclic compounds?

Among universities, judged by research, University of Mysore score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1University of MysoreIndia 10.034.8%123.1×8 +98.3%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Synthesis of heterocyclic compounds, country by country

Is Synthesis of heterocyclic compounds research growing?

Output in 2022-2025 was 11% lower than in 2018-2021, peaking in 2010.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Synthesis of heterocyclic compounds as a percentage of every work published that year, 0.0043% in 2024.

still counting0.025%0.050%0.075%Synthesis of heterocyclic compounds0.0040% in 202519801990200020102020

Fractional works of Synthesis of heterocyclic compounds over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Synthesis of heterocyclic compounds10.3% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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