Topic · T-cell and B-cell Immunology
Most cited papers in T-cell and B-cell Immunology
What are the most cited papers in T-cell and B-cell Immunology?
The most cited paper in T-cell and B-cell Immunology is "Integrated analysis of multimodal single-cell data" (Yuhan Hao et al., 2021), with 16,879 citations. Next come "Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities" (14,980) and "Dendritic cells and the control of immunity" (14,440).
Showing 50 of 100 papers. Every paper with more than 2,627 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Integrated analysis of multimodal single-cell data Yuhan Hao et al. · Cell | 31 May 2021 | 16,879 |
| 2 | Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities Sven Heinz, Christopher W. Benner, Nathanael J. Spann et al. · Molecular Cell | May 2010 | 14,980 |
| 3 | Dendritic cells and the control of immunity Jacques Banchereau, Ralph M. Steinman · Nature | Mar 1998 | 14,440 |
| 4 | Control of Regulatory T Cell Development by the Transcription Factor Foxp3 Shohei Hori, Takashi Nomura, Shimon Sakaguchi · Science | 13 Feb 2003 | 8,213 |
| 5 | Foxp3 programs the development and function of CD4+CD25+ regulatory T cells Jason D. Fontenot, Marc A. Gavin, Alexander Yu Rudensky · Nature Immunology | 3 Mar 2003 | 7,778 |
| 6 | Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Timothy R. Mosmann, Holly M. Cherwinski, M W Bond et al. · The Journal of Immunology | Apr 1986 | 7,553 |
| 7 | Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature | 30 Apr 2006 | 7,030 |
| 8 | Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm Timothy A. Springer · Cell | 1994 | 7,019 |
| 9 | Immunobiology of Dendritic Cells Jacques Banchereau, Francine Brière, Christophe Caux et al. · Annual Review of Immunology | Apr 2000 | 6,652 |
| 10 | Adhesion receptors of the immune system Timothy A. Springer · Nature | Aug 1990 | 6,541 |
| 11 | Alternative activation of macrophages Siamon Gordon · Nature reviews. Immunology | 2003 | 6,226 |
| 12 | What's wrong with Bonferroni adjustments Thomas Perneger · BMJ | 18 Apr 1998 | 5,951 |
| 13 | Two subsets of memory T lymphocytes with distinct homing potentials and effector functions Federica Sallusto, Danielle Lenig, Reinhold Förster et al. · Nature | Oct 1999 | 5,898 |
| 14 | Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology | 31 Jan 2010 | 5,851 |
| 15 | Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology | Aug 1995 | 5,571 |
| 16 | Regulatory T Cells and Immune Tolerance Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura et al. · Cell | May 2008 | 5,393 |
| 17 | Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine | 2 Oct 2000 | 5,324 |
| 18 | Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine | Apr 1994 | 5,185 |
| 19 | Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival Tyler Jay Curiel et al. · Nature Medicine | 22 Aug 2004 | 5,148 |
| 20 | IL-17 and Th17 Cells Thomas Korn, Estelle Bettelli, Mohamed Oukka et al. · Annual Review of Immunology | 8 Jan 2009 | 4,889 |
| 21 | Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology | 2 Oct 2005 | 4,759 |
| 22 | Molecular and cellular insights into T cell exhaustion E. John Wherry, Makoto Kurachi · Nature reviews. Immunology | 24 Jul 2015 | 4,739 |
| 23 | The Dendritic Cell System and its Role in Immunogenicity Ralph M. Steinman · Annual Review of Immunology | Apr 1991 | 4,722 |
| 24 | Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 WanJun Chen, Wenwen Jin, Neil J. Hardegen et al. · The Journal of Experimental Medicine | 15 Dec 2003 | 4,695 |
| 25 | Functional diversity of helper T lymphocytes Abul K. Abbas, KENNETH M. M. MURPHY, Alan Sher · Nature | 31 Oct 1996 | 4,488 |
| 26 | A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology | 2 Oct 2005 | 4,286 |
| 27 | Nomenclature for Factors of the HLA System, 2026 Steven G.E. Marsh et al. · Tissue Antigens | 17 Mar 2010 | 4,206 |
| 28 | T cell exhaustion E. John Wherry · Nature Immunology | 18 May 2011 | 4,131 |
| 29 | IL-23 drives a pathogenic T cell population that induces autoimmune inflammation Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine | 17 Jan 2005 | 4,112 |
| 30 | The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer Lu Zhang, Jianghao Xu, Xuan Zhang et al. · Cellular Physiology and Biochemistry | 2017 | 4,094 |
| 31 | Restoring function in exhausted CD8 T cells during chronic viral infection Daniel L. Barber, E. John Wherry, David Masopust et al. · Nature | 28 Dec 2005 | 4,031 |
| 32 | Somatic generation of antibody diversity Susumu Tonegawa · Nature | Apr 1983 | 4,012 |
| 33 | Functions of natural killer cells Eric D. Vivier, Elena Tomasello, Myriam Baratin et al. · Nature Immunology | 18 Apr 2008 | 3,951 |
| 34 | Chemokines Albert Zlotnik, Osamu Yoshie · Immunity | Feb 2000 | 3,882 |
| 35 | Of Mice and Not Men: Differences between Mouse and Human Immunology Javier Mestas, Christopher C.W. Hughes · The Journal of Immunology | Mar 2004 | 3,873 |
| 36 | Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. Kensuke Inaba, Muneo Inaba, Nikolaus Romani et al. · The Journal of Experimental Medicine | Dec 1992 | 3,789 |
| 37 | CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes Mirjana Efremova, Miquel Vento-Tormo, Sarah Amalia Teichmann et al. · Nature Protocols | 26 Feb 2020 | 3,773 |
| 38 | A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment Susanne J. Szabo, Sean T. Kim, Gina L. Costa et al. · Cell | Mar 2000 | 3,615 |
| 39 | TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity | Feb 2006 | 3,605 |
| 40 | A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature | Oct 1997 | 3,601 |
| 41 | Phenotypic Analysis of Antigen-Specific T Lymphocytes John D. Altman, Paul A. H. Moss, Philip Goulder et al. · Science | 4 Oct 1996 | 3,590 |
| 42 | A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma Pierre van der Bruggen, Catia Traversari, Patrick Chomez et al. · Science | 13 Dec 1991 | 3,560 |
| 43 | B lymphocytes secrete antigen-presenting vesicles. Graça Raposo, Hans W. Nijman, Willem Stoorvogel et al. · The Journal of Experimental Medicine | Mar 1996 | 3,552 |
| 44 | The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity Noa Stanietsky, Hrvoje Šimić, Jurica Arapović et al. · Proceedings of the National Academy of Sciences | 7 Oct 2009 | 3,551 |
| 45 | Differentiation of Effector CD4 T Cell Populations Jinfang Zhu, Hidehiro Yamane, William E. Paul · Annual Review of Immunology | Mar 2010 | 3,504 |
| 46 | Structure of the human class I histocompatibility antigen, HLA-A2 Pamela J. Björkman, Mark A. Saper, Boudjéma Samraoui et al. · Nature | Oct 1987 | 3,503 |
| 47 | How regulatory T cells work Dario A.A. Vignali, Lauren W. Collison, Creg J. Workman · Nature reviews. Immunology | 20 Jun 2008 | 3,464 |
| 48 | The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics | 2001 | 3,417 |
| 49 | Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants Loredana Ruggeri, Marusca Capanni, Elena Urbani et al. · Science | 15 Mar 2002 | 3,399 |
| 50 | Naturally occurring antibodies devoid of light chains Cécile Hamers‐Casterman, Touriya Atarhouch, Serge Muyldermans et al. · Nature | Jun 1993 | 3,325 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.