Most cited papers in Tissue Engineering and Regenerative Medicine
What are the most cited papers in Tissue Engineering and Regenerative Medicine?
The most cited paper in Tissue Engineering and Regenerative Medicine is "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al., 2007), with 20,424 citations. Next come "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014) and "Embryonic Stem Cell Lines Derived from Human Blastocysts" (16,067).
Showing 50 of 100 papers. Every paper with more than 1,438 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell | Nov 2007 | 20,424 |
| 2 | Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy | 2006 | 18,014 |
| 3 | Embryonic Stem Cell Lines Derived from Human Blastocysts James Alexander Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science | 6 Nov 1998 | 16,067 |
| 4 | Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science | 14 May 1993 | 9,666 |
| 5 | Mesenchymal stem cells Arnold I. Caplan · Journal of Orthopaedic Research® | Sep 1991 | 6,558 |
| 6 | Wound repair and regeneration Geoffrey C. Gurtner, Sabine Werner, Yann Barrandon et al. · Nature | 14 May 2008 | 6,500 |
| 7 | Hydrogels for Tissue Engineering Kuen Yong Lee, David J. Mooney · Chemical Reviews | 31 May 2001 | 5,279 |
| 8 | Bone marrow cells regenerate infarcted myocardium Donald Orlic, Jan Kajstura, Stefano Chimenti et al. · Nature | 5 Apr 2001 | 5,184 |
| 9 | Foreign body reaction to biomaterials James Melvin Anderson, Analiz Rodriguez, David T. Chang · Seminars in Immunology | 7 Jan 2008 | 5,112 |
| 10 | The extracellular matrix at a glance Christian Frantz, Kathleen M. Stewart, Valerie Marie Weaver · Journal of Cell Science | Dec 2010 | 4,397 |
| 11 | Myofibroblasts and mechano-regulation of connective tissue remodelling James J. Tomasek, Giulio Gabbiani, Boris Hinz et al. · Nature Reviews Molecular Cell Biology | May 2002 | 4,302 |
| 12 | A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs Mihaela Crisan et al. · Cell stem cell | Sep 2008 | 4,028 |
| 13 | The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression Amparo Martínez Cano, Mirna Pérez‐Moreno, Isabel Rodrigo et al. · Nature Cell Biology | 13 Jan 2000 | 3,685 |
| 14 | An overview of tissue and whole organ decellularization processes Peter M. Crapo, Thomas W. Gilbert, Stephen F. Badylak · Biomaterials | 6 Feb 2011 | 3,621 |
| 15 | Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration Antonio Paolo Beltrami, Laura Barlucchi, Daniele Torella et al. · Cell | Sep 2003 | 3,553 |
| 16 | Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue Susanne Kern, Hermann Eichler, Johannes Stoeve et al. · Stem Cells | 12 Jan 2006 | 3,431 |
| 17 | Biomaterials & scaffolds for tissue engineering Fergal J. O’Brien · Materials Today | Mar 2011 | 3,424 |
| 18 | Electrospinning: Applications in drug delivery and tissue engineering Travis J. Sill, Horst A. von Recum · Biomaterials | 7 Mar 2008 | 3,286 |
| 19 | Mesenchymal stem cells as trophic mediators Arnold I. Caplan, James E. Dennis · Journal of Cellular Biochemistry | 17 Apr 2006 | 3,021 |
| 20 | Organogenesis in a dish: Modeling development and disease using organoid technologies Madeline A. Lancaster, Juergen A. Knoblich · Science | 17 Jul 2014 | 2,936 |
| 21 | Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells Katarina Le Blanc, Ida Rasmusson, Berit Sundberg et al. · The Lancet | May 2004 | 2,762 |
| 22 | On the mechanisms of biocompatibility David F. Williams · Biomaterials | 29 Apr 2008 | 2,746 |
| 23 | Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors Giuliana Ferrari, Gabriella Cusella, De Angelis et al. · Science | 6 Mar 1998 | 2,742 |
| 24 | Growth Factors, Matrices, and Forces Combine and Control Stem Cells Dennis E. Discher, David J. Mooney, Peter W. Zandstra · Science | 25 Jun 2009 | 2,674 |
| 25 | Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size Qiu Li Loh, Cleo S.N. Choong · Tissue Engineering Part B Reviews | 14 May 2013 | 2,667 |
| 26 | Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart Harald C. Ott, Thomas S. Matthiesen, Saik-Kia Goh et al. · Nature Medicine | 13 Jan 2008 | 2,656 |
| 27 | Transient Regenerative Potential of the Neonatal Mouse Heart Enzo R. Porrello, Ahmed I. Mahmoud, Emma Simpson et al. · Science | 24 Feb 2011 | 2,649 |
| 28 | Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function Alfred A. Kocher, Michael Schuster, M Szabolcs et al. · Nature Medicine | Apr 2001 | 2,551 |
| 29 | Mesenchymal stem cells reside in virtually all post-natal organs and tissues Lindolfo da Silva Meirelles, Pedro César Chagastelles, Nance Beyer Nardi · Journal of Cell Science | 9 May 2006 | 2,507 |
| 30 | Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors Masaki Ieda, Ji‐Dong Fu, Paul Delgado-Olguı́n et al. · Cell | Aug 2010 | 2,491 |
| 31 | Electrospun nanofibrous structure: A novel scaffold for tissue engineering Wan‐Ju Li, Cato T. Laurencin, Edward J. Caterson et al. · Journal of Biomedical Materials Research | 25 Mar 2002 | 2,433 |
| 32 | Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production Krisztián Németh, Asada Leelahavanichkul, Peter S.T. Yuen et al. · Nature Medicine | 21 Nov 2008 | 2,378 |
| 33 | Pax7 Is Required for the Specification of Myogenic Satellite Cells Patrick Seale, Luc A. Sabourin, Adele Girgis-Gabardo et al. · Cell | Sep 2000 | 2,363 |
| 34 | Tissue Engineering--Current Challenges and Expanding Opportunities Linda G. Griffith, Gail K. Naughton · Science | 8 Feb 2002 | 2,359 |
| 35 | Adipose-Derived Stem Cells for Regenerative Medicine Jeffrey M. Gimble, Adam J. Katz, Bruce Alan Bunnell · Circulation Research | 10 May 2007 | 2,350 |
| 36 | Alginate hydrogels as synthetic extracellular matrix materials Jon A. Rowley, Gerard J. Madlambayan, David J. Mooney · Biomaterials | 1999 | 2,348 |
| 37 | Bone Tissue Engineering: Recent Advances and Challenges Ami R. Amini, Cato T. Laurencin, Syam Prasad Nukavarapu · Critical Reviews in Biomedical Engineering | 2012 | 2,347 |
| 38 | Extracellular Matrix Degradation and Remodeling in Development and Disease Pengfei Lu, Ken Takai, Valerie Marie Weaver et al. · Cold Spring Harbor Perspectives in Biology | 14 Sep 2011 | 2,320 |
| 39 | 22q11.2 deletion syndrome Donna M. McDonald‐McGinn, Kathleen E. Sullivan, Bruno Marino et al. · Nature Reviews Disease Primers | 18 Nov 2015 | 2,278 |
| 40 | Electrospinning of Polymeric Nanofibers for Tissue Engineering Applications: A Review Quynh P. Pham, Upma Sharma, Antonios G. Mikos · Tissue Engineering | May 2006 | 2,254 |
| 41 | Electrospinning of Collagen Nanofibers Jamil A. Matthews, Gary E. Wnek, David G. Simpson et al. · Biomacromolecules | 26 Jan 2002 | 2,248 |
| 42 | Endothelial-to-mesenchymal transition contributes to cardiac fibrosis Elisabeth Maria Zeisberg, Oleg Tarnavski, Michael Zeisberg et al. · Nature Medicine | 29 Jul 2007 | 2,242 |
| 43 | Satellite Cells and the Muscle Stem Cell Niche Hang Yin, Feodor D. Price, Michael A. Rudnicki · Physiological Reviews | 2013 | 2,237 |
| 44 | Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Michael A. Laflamme, Kent Y Chen, Anna V. Naumova et al. · Nature Biotechnology | 26 Aug 2007 | 2,229 |
| 45 | Decellularization of tissues and organs Thomas W. Gilbert, Tiffany L. Sellaro, Stephen F. Badylak · Biomaterials | 8 Mar 2006 | 2,201 |
| 46 | Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial Kai Christoph Wollert, Gerd Peter Meyer, Joachim Lotz et al. · The Lancet | Jul 2004 | 2,196 |
| 47 | Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts Charles E. Murry, Mark H. Soonpaa, Hans Reinecke et al. · Nature | 21 Mar 2004 | 2,159 |
| 48 | Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle David Yaffe, Ora Saxel · Nature | Dec 1977 | 2,158 |
| 49 | Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide Guangwen Ren, Liying Zhang, Xin Zhao et al. · Cell stem cell | Feb 2008 | 2,156 |
| 50 | Mobilized bone marrow cells repair the infarcted heart, improving function and survival Donald Orlic, Jan Kajstura, Stefano Chimenti et al. · Proceedings of the National Academy of Sciences | 14 Aug 2001 | 2,097 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.