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Most cited papers in Tissue Engineering and Regenerative Medicine

Tissue Engineering and Regenerative Medicine

What are the most cited papers in Tissue Engineering and Regenerative Medicine?

The most cited paper in Tissue Engineering and Regenerative Medicine is "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al., 2007), with 20,424 citations. Next come "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014) and "Embryonic Stem Cell Lines Derived from Human Blastocysts" (16,067).

Showing 50 of 100 papers. Every paper with more than 1,438 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell Nov 2007 20,424
2 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy 2006 18,014
3 Embryonic Stem Cell Lines Derived from Human Blastocysts James Alexander Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science 6 Nov 1998 16,067
4 Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science 14 May 1993 9,666
5 Mesenchymal stem cells Arnold I. Caplan · Journal of Orthopaedic Research® Sep 1991 6,558
6 Wound repair and regeneration Geoffrey C. Gurtner, Sabine Werner, Yann Barrandon et al. · Nature Open access 14 May 2008 6,500
7 Hydrogels for Tissue Engineering Kuen Yong Lee, David J. Mooney · Chemical Reviews Review 31 May 2001 5,279
8 Bone marrow cells regenerate infarcted myocardium Donald Orlic, Jan Kajstura, Stefano Chimenti et al. · Nature 5 Apr 2001 5,184
9 Foreign body reaction to biomaterials James Melvin Anderson, Analiz Rodriguez, David T. Chang · Seminars in Immunology Open access 7 Jan 2008 5,112
10 The extracellular matrix at a glance Christian Frantz, Kathleen M. Stewart, Valerie Marie Weaver · Journal of Cell Science Open access Dec 2010 4,397
11 Myofibroblasts and mechano-regulation of connective tissue remodelling James J. Tomasek, Giulio Gabbiani, Boris Hinz et al. · Nature Reviews Molecular Cell Biology Review May 2002 4,302
12 A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs Mihaela Crisan et al. · Cell stem cell Open access Sep 2008 4,028
13 The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression Amparo Martínez Cano, Mirna Pérez‐Moreno, Isabel Rodrigo et al. · Nature Cell Biology 13 Jan 2000 3,685
14 An overview of tissue and whole organ decellularization processes Peter M. Crapo, Thomas W. Gilbert, Stephen F. Badylak · Biomaterials Open access 6 Feb 2011 3,621
15 Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration Antonio Paolo Beltrami, Laura Barlucchi, Daniele Torella et al. · Cell Open access Sep 2003 3,553
16 Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue Susanne Kern, Hermann Eichler, Johannes Stoeve et al. · Stem Cells 12 Jan 2006 3,431
17 Biomaterials & scaffolds for tissue engineering Fergal J. O’Brien · Materials Today Open access Mar 2011 3,424
18 Electrospinning: Applications in drug delivery and tissue engineering Travis J. Sill, Horst A. von Recum · Biomaterials 7 Mar 2008 3,286
19 Mesenchymal stem cells as trophic mediators Arnold I. Caplan, James E. Dennis · Journal of Cellular Biochemistry 17 Apr 2006 3,021
20 Organogenesis in a dish: Modeling development and disease using organoid technologies Madeline A. Lancaster, Juergen A. Knoblich · Science 17 Jul 2014 2,936
21 Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells Katarina Le Blanc, Ida Rasmusson, Berit Sundberg et al. · The Lancet May 2004 2,762
22 On the mechanisms of biocompatibility David F. Williams · Biomaterials 29 Apr 2008 2,746
23 Muscle Regeneration by Bone Marrow-Derived Myogenic Progenitors Giuliana Ferrari, Gabriella Cusella, De Angelis et al. · Science Open access 6 Mar 1998 2,742
24 Growth Factors, Matrices, and Forces Combine and Control Stem Cells Dennis E. Discher, David J. Mooney, Peter W. Zandstra · Science Open access 25 Jun 2009 2,674
25 Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size Qiu Li Loh, Cleo S.N. Choong · Tissue Engineering Part B Reviews Open access 14 May 2013 2,667
26 Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart Harald C. Ott, Thomas S. Matthiesen, Saik-Kia Goh et al. · Nature Medicine 13 Jan 2008 2,656
27 Transient Regenerative Potential of the Neonatal Mouse Heart Enzo R. Porrello, Ahmed I. Mahmoud, Emma Simpson et al. · Science Open access 24 Feb 2011 2,649
28 Neovascularization of ischemic myocardium by human bone-marrow–derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function Alfred A. Kocher, Michael Schuster, M Szabolcs et al. · Nature Medicine Apr 2001 2,551
29 Mesenchymal stem cells reside in virtually all post-natal organs and tissues Lindolfo da Silva Meirelles, Pedro César Chagastelles, Nance Beyer Nardi · Journal of Cell Science 9 May 2006 2,507
30 Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors Masaki Ieda, Ji‐Dong Fu, Paul Delgado-Olguı́n et al. · Cell Open access Aug 2010 2,491
31 Electrospun nanofibrous structure: A novel scaffold for tissue engineering Wan‐Ju Li, Cato T. Laurencin, Edward J. Caterson et al. · Journal of Biomedical Materials Research 25 Mar 2002 2,433
32 Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production Krisztián Németh, Asada Leelahavanichkul, Peter S.T. Yuen et al. · Nature Medicine Open access 21 Nov 2008 2,378
33 Pax7 Is Required for the Specification of Myogenic Satellite Cells Patrick Seale, Luc A. Sabourin, Adele Girgis-Gabardo et al. · Cell Open access Sep 2000 2,363
34 Tissue Engineering--Current Challenges and Expanding Opportunities Linda G. Griffith, Gail K. Naughton · Science 8 Feb 2002 2,359
35 Adipose-Derived Stem Cells for Regenerative Medicine Jeffrey M. Gimble, Adam J. Katz, Bruce Alan Bunnell · Circulation Research Open access 10 May 2007 2,350
36 Alginate hydrogels as synthetic extracellular matrix materials Jon A. Rowley, Gerard J. Madlambayan, David J. Mooney · Biomaterials 1999 2,348
37 Bone Tissue Engineering: Recent Advances and Challenges Ami R. Amini, Cato T. Laurencin, Syam Prasad Nukavarapu · Critical Reviews in Biomedical Engineering Open access 2012 2,347
38 Extracellular Matrix Degradation and Remodeling in Development and Disease Pengfei Lu, Ken Takai, Valerie Marie Weaver et al. · Cold Spring Harbor Perspectives in Biology Open access 14 Sep 2011 2,320
39 22q11.2 deletion syndrome Donna M. McDonald‐McGinn, Kathleen E. Sullivan, Bruno Marino et al. · Nature Reviews Disease Primers ReviewOpen access 18 Nov 2015 2,278
40 Electrospinning of Polymeric Nanofibers for Tissue Engineering Applications: A Review Quynh P. Pham, Upma Sharma, Antonios G. Mikos · Tissue Engineering May 2006 2,254
41 Electrospinning of Collagen Nanofibers Jamil A. Matthews, Gary E. Wnek, David G. Simpson et al. · Biomacromolecules 26 Jan 2002 2,248
42 Endothelial-to-mesenchymal transition contributes to cardiac fibrosis Elisabeth Maria Zeisberg, Oleg Tarnavski, Michael Zeisberg et al. · Nature Medicine 29 Jul 2007 2,242
43 Satellite Cells and the Muscle Stem Cell Niche Hang Yin, Feodor D. Price, Michael A. Rudnicki · Physiological Reviews ReviewOpen access 2013 2,237
44 Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Michael A. Laflamme, Kent Y Chen, Anna V. Naumova et al. · Nature Biotechnology 26 Aug 2007 2,229
45 Decellularization of tissues and organs Thomas W. Gilbert, Tiffany L. Sellaro, Stephen F. Badylak · Biomaterials 8 Mar 2006 2,201
46 Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial Kai Christoph Wollert, Gerd Peter Meyer, Joachim Lotz et al. · The Lancet Jul 2004 2,196
47 Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts Charles E. Murry, Mark H. Soonpaa, Hans Reinecke et al. · Nature 21 Mar 2004 2,159
48 Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle David Yaffe, Ora Saxel · Nature Dec 1977 2,158
49 Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide Guangwen Ren, Liying Zhang, Xin Zhao et al. · Cell stem cell Open access Feb 2008 2,156
50 Mobilized bone marrow cells repair the infarcted heart, improving function and survival Donald Orlic, Jan Kajstura, Stefano Chimenti et al. · Proceedings of the National Academy of Sciences Open access 14 Aug 2001 2,097

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.