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Tissue Engineering and Regenerative Medicine

Tissue Engineering and Regenerative Medicine is a research topic within Surgery. Science Explorer counts 42k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers revolves around the field of tissue engineering and regenerative medicine, with a focus on decellularization, extracellular matrix, organ engineering, bioartificial organs, and the development of scaffold materials for various tissue types. It also encompasses research on cardiac tissue engineering, biologic scaffolds, tissue-specific coatings, and the application of stem cell therapy in tissue regeneration.

  • Decellularization
  • Extracellular Matrix
  • Organ Engineering
  • Bioartificial Organs
  • Regenerative Medicine
  • Scaffold Materials
  • Cardiac Tissue Engineering
  • Biologic Scaffolds
  • Tissue-Specific Coatings
  • Stem Cell Therapy
Research works
42k
fractional, since 1950
In the world top 10%
4.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-1%
the tick is no change
Largest producer
China
33% of the 10 largest, 2022-now
Tissue Engineering and Regenerative Medicine

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Tissue Engineering and Regenerative Medicine research?

By volume, China and the United States publish the most (1.9k and 1.7k works in 2022-now).

By volume, 2022-now

  1. 1 China 1.9k works
  2. 2 United States 1.7k works
  3. 3 Japan 370 works
  4. 4 India 343 works
  5. 5 Germany 319 works
  6. 6 Iran 293 works
  7. 7 South Korea 262 works
  8. 8 United Kingdom 247 works
  9. 9 Italy 232 works
  10. 10 Canada 173 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 32.7%United States: 29.0%Japan: 6.3%India: 5.9%6 others listed: 26.1%33%largest
China1,909 · 32.7%United States1,691 · 29.0%Japan370 · 6.3%India343 · 5.9%6 others listed1,526 · 26.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Tissue Engineering and Regenerative Medicine research?

By volume in 2022-now, Shanghai Jiao Tong University publishes the most Tissue Engineering and Regenerative Medicine research, followed by Sichuan University and Harvard University.

By volume, 2022-now

  1. 1 Shanghai Jiao Tong UniversityChina 76 works
  2. 2 Sichuan UniversityChina 74 works
  3. 3 Harvard UniversityUnited States 68 works
  4. 4 Chinese Academy of SciencesChina 55 works
  5. 5 Zhejiang UniversityChina 44 works
  6. 6 Centre National de la Recherche ScientifiqueFrance 42 works
  7. 7 Southern Medical UniversityChina 41 works
  8. 8 Sun Yat-sen UniversityChina 41 works
  9. 9 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 38 works
  10. 10 Russian Academy of SciencesRussia 36 works

Who are the leading researchers in Tissue Engineering and Regenerative Medicine?

The most-cited researchers publishing on Tissue Engineering and Regenerative Medicine include David Moher, Jun Wang and Stephan Windecker.

  1. 1 David Moher Canada 898k citations
  2. 2 Jun Wang China 340k citations
  3. 3 Stephan Windecker Switzerland 338k citations
  4. 4 Giuseppe Remuzzi Italy 328k citations
  5. 5 Róbert Langer United States 303k citations
  6. 6 Jeremy Grimshaw Canada 281k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Tissue Engineering and Regenerative Medicine?

The most cited paper in Tissue Engineering and Regenerative Medicine is "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al., 2007), with 20,424 citations. Next come "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014) and "Embryonic Stem Cell Lines Derived from Human Blastocysts" (16,067).

Most cited papers
#PaperReleasedCitations
1 Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell Nov 2007 20,424
2 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy 2006 18,014
3 Embryonic Stem Cell Lines Derived from Human Blastocysts James Alexander Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science 6 Nov 1998 16,067
4 Tissue Engineering Róbert Langer, Joseph P. Vacanti · Science 14 May 1993 9,666
5 Mesenchymal stem cells Arnold I. Caplan · Journal of Orthopaedic Research® Sep 1991 6,558
All 100 most cited papers, with filters and sorting

Where is Tissue Engineering and Regenerative Medicine research done?

The largest centres of Tissue Engineering and Regenerative Medicine research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Tehran (Iran).

Largest cities, 2022-now

  1. 1 BeijingChina 264 works
  2. 2 ShanghaiChina 203 works
  3. 3 GuangzhouChina 152 works
  4. 4 TehranIran 150 works
  5. 5 TokyoJapan 120 works
  6. 6 SeoulSouth Korea 116 works
  7. 7 ChengduChina 98 works
  8. 8 LondonUnited Kingdom 80 works
  9. 9 HangzhouChina 78 works
  10. 10 MoscowRussia 77 works
See Tissue Engineering and Regenerative Medicine on the map

Where is the best place to study Tissue Engineering and Regenerative Medicine?

Among universities, judged by research, Sichuan University, Southern Medical University and Harvard University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 18.78%fractional works in this field (log) →share of work in the world top 10% →Southern Medical Uni…Shanghai Jiao Tong U…Sichuan UniversityHarvard University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Sichuan UniversityChina 70.617.8%4.8×74 +49.7%
2Southern Medical UniversityChina 69.620.7%9.7×41 +80.9%
3Harvard UniversityUnited States 67.514.3%3.1×68 -9.2%
4Shanghai Jiao Tong UniversityChina 65.918.2%3.8×76 +4.3%
5Zhejiang UniversityChina 61.222.2%2.4×44 -6.0%
6Tabriz University of Medical SciencesIran 59.520.4%8.7×16 +17.9%
7Soochow UniversityChina 58.720.4%3.8×26 +35.1%
8Peking UniversityChina 58.216.9%2.6×36 +46.6%
9Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 58.115.8%5.2×38 +52.7%
10Nankai UniversityChina 57.221.1%3.7×18 +17.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Tissue Engineering and Regenerative Medicine, country by country

Is Tissue Engineering and Regenerative Medicine research growing?

Output in 2022-2025 was 1% lower than in 2018-2021, peaking in 2021.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Tissue Engineering and Regenerative Medicine as a percentage of every work published that year, 0.032% in 2024.

still counting0.020%0.040%0.060%Tissue Engineering and Regenerative Medicine0.033% in 202519801990200020102020

Fractional works of Tissue Engineering and Regenerative Medicine over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Tissue Engineering and Regenerative Medicine9.8% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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