Pancreatic function and diabetes

Pancreatic function and diabetes is a research topic within Surgery. Science Explorer counts 73k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the dysfunction and regeneration of pancreatic islets, particularly related to ß-cell deficit, insulin secretion, diabetes mellitus, islet transplantation, glucose homeostasis, stem cell differentiation, oxidative stress, and pancreas development. The research covers various aspects of pancreatic islet biology and potential therapeutic approaches for addressing islet dysfunction in diabetes.

Pancreatic Islets
ß-Cell Dysfunction
Insulin Secretion
Diabetes Mellitus
Islet Transplantation
Glucose Homeostasis
Stem Cell Differentiation
Oxidative Stress
Pancreas Development
Endocrine Cell Lineages

Research works: 73k
In the world top 10%: 7.2k
Top-10% rate: 9.9%
Growth, 2018-21 → 2022-25: +1%
Largest producer: United States

Pancreatic function and diabetes

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Pancreatic function and diabetes research?

By volume, the United States and China publish the most (2.4k and 1.6k works in 2022-now).

By volume, 2022-now

1 United States 2.4k works
2 China 1.6k works
3 India 529 works
4 Japan 484 works
5 United Kingdom 407 works
6 Germany 356 works
7 Italy 306 works
8 Canada 268 works
9 South Korea 238 works
10 France 210 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States2,442 · 35.5%China1,639 · 23.8%India529 · 7.7%Japan484 · 7.0%6 others listed1,785 · 25.9%

Shares of the rows listed above, not of the whole node.

Which institutions lead Pancreatic function and diabetes research?

By volume in 2022-now, Harvard University publishes the most Pancreatic function and diabetes research, followed by Peking University and University of Toronto.

By volume, 2022-now

1 Harvard UniversityUnited States 98 works
2 Peking UniversityChina 51 works
3 University of TorontoCanada 46 works
4 University of CopenhagenDenmark 45 works
5 Shanghai Jiao Tong UniversityChina 43 works
6 Indiana UniversityUnited States 43 works
7 Centre National de la Recherche ScientifiqueFrance 42 works
8 Chinese Academy of SciencesChina 42 works
9 InsermFrance 42 works
10 Russian Academy of SciencesRussia 40 works

Who are the leading researchers in Pancreatic function and diabetes?

The most-cited researchers publishing on Pancreatic function and diabetes include Eric S. Lander, George Davey Smith and Mark J. Daly.

1 Eric S. Lander United States 524k citations
2 George Davey Smith United Kingdom 435k citations
3 Mark J. Daly United States 403k citations
4 Stacey L. Gabriel United States 402k citations
5 Guido Kroemer France 386k citations
6 Bert Vogelstein United States 373k citations
7 Gad A. Getz United States 364k citations
8 Jost Bruno Jonas Germany 350k citations
9 John J.V. McMurray United Kingdom 349k citations
10 Shizuo Akira Japan 342k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Pancreatic function and diabetes?

The most cited paper in Pancreatic function and diabetes is "Positional cloning of the mouse obese gene and its human homologue" (Yiying Zhang, Ricardo Proenca, Margherita Maffei et al., 1994), with 13,483 citations. Next come "Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes" (7,908) and "Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche" (7,361).

Most cited papers
#	Paper	Released	Citations
1	Positional cloning of the mouse obese gene and its human homologue Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature	Dec 1994	13,483
2	Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes Bruce Charles Neal, Vlado Perkovic, Kenneth W. Mahaffey et al. · New England Journal of Medicine Open access	12 Jun 2017	7,908
3	Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature	29 Mar 2009	7,361
4	AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology Open access	23 Jan 2011	7,286
5	Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction John J.V. McMurray et al. · New England Journal of Medicine Open access	19 Sep 2019	7,135

All 99 most cited papers, with filters and sorting

Where is Pancreatic function and diabetes research done?

The largest centres of Pancreatic function and diabetes research in 2022-now are Beijing (China), Shanghai (China), Tokyo (Japan) and Seoul (South Korea). Among places with at least 20 works in it, it is an unusually large share of all research in Aurora and Indianapolis.

Largest cities, 2022-now

1 BeijingChina 229 works
2 ShanghaiChina 145 works
3 TokyoJapan 122 works
4 SeoulSouth Korea 118 works
5 GuangzhouChina 106 works
6 LondonUnited Kingdom 103 works
7 New YorkUnited States 96 works
8 NanjingChina 95 works
9 ParisFrance 93 works
10 BostonUnited States 80 works

Where it is the local speciality

AuroraUS · 53.1 works14×
IndianapolisUS · 50.0 works8.4×

← less than its size predicts1×more →

Location quotient: how much more of its research is in Pancreatic function and diabetes than the world average.

See Pancreatic function and diabetes on the map

Where is the best place to study Pancreatic function and diabetes?

Among universities, judged by research, Harvard University, University of Colorado Anschutz Medical Campus and University of Virginia score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged

40%

Specialisationhow much of its work is in this field, counted up to 10× the world share

10%

Sizeits output in this field, on a log scale

30%

Growthoutput growth, counted from -20% to +20%

10%

Internationalshare of its work with a co-author abroad

10%

Each slider sets a weight; the share it gets of the score is beside it.

#	University	Score	Top 10%	Specialisation	Works	Growth
1	Harvard UniversityUnited States	78.7	15.0%	3.7×	98	-15.0%
2	University of Colorado Anschutz Medical CampusUnited States	68.2	15.6%	15.0×	33	+42.5%
3	University of VirginiaUnited States	63.5	15.1%	5.9×	31	+30.5%
4	University of CopenhagenDenmark	62.3	13.0%	5.8×	45	-14.0%
5	Sichuan UniversityChina	61.4	18.3%	2.0×	39	+69.8%
6	Peking UniversityChina	61.0	12.4%	3.0×	51	+52.7%
7	University of CambridgeUnited Kingdom	60.6	21.4%	2.2×	23	-28.7%
8	University of California San DiegoUnited States	60.1	19.8%	2.7×	22	-29.8%
9	National and Kapodistrian University of AthensGreece	60.0	25.0%	2.6×	11	+40.3%
10	University of TorontoCanada	59.9	14.0%	2.7×	46	-23.9%
11	University of OxfordUnited Kingdom	58.2	18.1%	2.3×	27	-24.1%
12	Stanford UniversityUnited States	57.9	11.8%	2.8×	35	-14.4%
13	Johns Hopkins UniversityUnited States	57.8	10.5%	2.4×	32	+8.2%
14	Cornell UniversityUnited States	57.3	11.8%	2.6×	29	+27.8%
15	Zhejiang UniversityChina	56.6	15.2%	1.6×	36	+28.5%
16	University of MichiganUnited States	56.0	12.9%	2.9×	37	+0.4%
17	Imperial College LondonUnited Kingdom	55.3	18.3%	2.1×	18	-38.3%
18	Baylor College of MedicineUnited States	55.2	12.9%	5.2×	22	+18.1%
19	Washington University in St. LouisUnited States	54.8	12.4%	5.5×	33	-14.7%
20	Vanderbilt UniversityUnited States	54.7	9.4%	6.3×	38	-14.0%
21	University of California, San FranciscoUnited States	54.7	15.1%	3.1×	19	-23.8%
22	University of FloridaUnited States	54.3	13.3%	3.3×	29	+2.9%
23	Heinrich Heine University DüsseldorfGermany	54.2	17.5%	8.5×	26	-34.3%
24	University of HelsinkiFinland	53.8	19.1%	2.6×	15	-6.1%
25	University of ExeterUnited Kingdom	53.6	15.6%	4.5×	16	-12.6%
26	Indiana UniversityUnited States	51.9	13.3%	5.3×	43	-19.2%
27	University of PennsylvaniaUnited States	51.9	13.9%	3.0×	27	-16.0%
28	Yale UniversityUnited States	51.6	12.8%	3.1×	28	-28.6%
29	University of British ColumbiaCanada	51.6	8.9%	2.7×	28	+15.4%
30	University of WashingtonUnited States	51.5	14.5%	2.5×	24	-13.1%
31	University of MiamiUnited States	51.4	11.8%	6.9×	36	-9.1%
32	Technische Universität DresdenGermany	50.7	17.1%	3.7×	17	-5.2%
33	University of Naples Federico IIItaly	50.6	23.9%	1.7×	10	+17.0%
34	University of GroningenNetherlands	50.5	13.3%	3.1×	18	-12.0%
35	Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina	50.4	16.2%	2.9×	25	+11.9%
36	Sun Yat-sen UniversityChina	50.3	10.6%	2.0×	34	+38.3%
37	Karolinska InstitutetSweden	50.0	12.9%	4.7×	22	-22.3%
38	McMaster UniversityCanada	49.6	18.9%	1.8×	8	+28.0%
39	Case Western Reserve UniversityUnited States	49.3	14.8%	2.8×	14	+43.5%
40	Medical University of LodzPoland	49.0	22.9%	6.8×	9	+2.1%
41	Shanghai Jiao Tong UniversityChina	48.7	13.8%	1.8×	43	-0.3%
42	University of GothenburgSweden	48.4	20.8%	2.8×	11	-21.6%
43	University of ZurichSwitzerland	47.1	20.9%	1.5×	9	-18.5%
44	Duke UniversityUnited States	45.9	18.3%	1.9×	13	-20.5%
45	University of Colorado DenverUnited States	45.2	13.3%	7.0×	19	-32.3%
46	Nanjing Medical UniversityChina	45.1	9.3%	5.1×	38	+5.9%
47	Chinese University of Hong KongChina	44.7	10.0%	2.2×	14	+34.6%
48	University of GenevaSwitzerland	44.7	11.4%	3.6×	12	-36.1%
49	University College LondonUnited Kingdom	43.6	17.3%	1.1×	14	-14.6%
50	Medical University of GrazAustria	43.3	9.2%	8.8×	9	+17.9%
51	KU LeuvenBelgium	39.7	11.3%	1.8×	14	-17.5%
52	Medical University of BiałystokPoland	39.4	12.1%	12.9×	9	+15.2%
53	King Saud UniversitySaudi Arabia	37.4	8.4%	1.5×	12	+108.1%
54	National University of SingaporeSingapore	36.4	16.9%	1.1×	11	-37.8%
55	University of UlsterUnited Kingdom	32.1	6.4%	10.2×	12	-20.6%
56	Radboud University NijmegenNetherlands	31.9	4.8%	1.8×	9	+29.3%
57	Gunma UniversityJapan	29.3	2.7%	13.7×	12	+12.5%
58	Yokohama City UniversityJapan	24.6	10.9%	7.1×	8	-18.9%
59	Tokushima UniversityJapan	17.9	1.1%	9.7×	10	-32.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Pancreatic function and diabetes, country by country

Is Pancreatic function and diabetes research growing?

Output in 2022-2025 was 1% higher than in 2018-2021, peaking in 2021. The fastest-growing topics are Pancreatic function and diabetes.

grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Pancreatic function and diabetes as a percentage of every work published that year, 0.042% in 2024.

Fractional works of Pancreatic function and diabetes over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

Discussion

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Which countries lead Pancreatic function and diabetes research?

By volume, 2022-now

How concentrated that is

Which institutions lead Pancreatic function and diabetes research?

By volume, 2022-now

Who are the leading researchers in Pancreatic function and diabetes?

What are the most cited papers in Pancreatic function and diabetes?

Where is Pancreatic function and diabetes research done?

Largest cities, 2022-now

Where it is the local speciality

Where is the best place to study Pancreatic function and diabetes?

Is Pancreatic function and diabetes research growing?

Its share of all research

How much of it reaches the world top 10%

Which topics inside it are moving

Related research

Discussion