Most cited papers in Toxin Mechanisms and Immunotoxins
What are the most cited papers in Toxin Mechanisms and Immunotoxins?
The most cited paper in Toxin Mechanisms and Immunotoxins is "Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses" (M. F. Clark, A.N. Adams, 1977), with 4,838 citations. Next come "Genistein, a specific inhibitor of tyrosine-specific protein kinases." (3,750) and "Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein" (3,390).
Showing 50 of 100 papers. Every paper with more than 994 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Characteristics of the Microplate Method of Enzyme-Linked Immunosorbent Assay for the Detection of Plant Viruses M. F. Clark, A.N. Adams · Journal of General Virology | Mar 1977 | 4,838 |
| 2 | Genistein, a specific inhibitor of tyrosine-specific protein kinases. Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry | Apr 1987 | 3,750 |
| 3 | Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein F. Ulrich Hartl, Manajit K. Hayer-Hartl · Science | 8 Mar 2002 | 3,390 |
| 4 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Rudy L. Juliano, Victor Wei Teik Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes | Nov 1976 | 3,310 |
| 5 | Hsp70 chaperones: Cellular functions and molecular mechanism Matthias P. Mayer, Bernd Bukau · Cellular and Molecular Life Sciences | Mar 2005 | 2,919 |
| 6 | Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot et al. · Nature Cell Biology | 8 May 2000 | 2,917 |
| 7 | Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation Johannes Gerdes, Ulrich Schwab, Hilmar Lemke et al. · International Journal of Cancer | 15 Jan 1983 | 2,849 |
| 8 | The Hsp70 and Hsp60 Chaperone Machines Bernd Bukau, Arthur L. Horwich · Cell | Feb 1998 | 2,833 |
| 9 | Role of plant heat-shock proteins and molecular chaperones in the abiotic stress response Wang‐Xia Wang, Basia Vinocur, Oded Shoseyov et al. · Trends in Plant Science | 20 Mar 2004 | 2,803 |
| 10 | A note on quantifying follow-up in studies of failure time MICHAEL SCHEMPER, Terry L. Smith · Controlled Clinical Trials | Aug 1996 | 2,609 |
| 11 | Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE Yuri A. Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature | Sep 1994 | 2,585 |
| 12 | Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences Julian Downward, Yosef Yarden, E. L. V. Mayes et al. · Nature | Feb 1984 | 2,547 |
| 13 | Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity Giorgio Trinchieri · Annual Review of Immunology | Apr 1995 | 2,433 |
| 14 | Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore Langzhou Song, Michael R. Hobaugh, C. Shustak et al. · Science | 13 Dec 1996 | 2,390 |
| 15 | Analysis of membrane and surface protein sequences with the hydrophobic moment plot David S Eisenberg, Erich M. Schwarz, Michael C. Komaromy et al. · Journal of Molecular Biology | Oct 1984 | 2,335 |
| 16 | THE FUNCTION OF HEAT-SHOCK PROTEINS IN STRESS TOLERANCE: DEGRADATION AND REACTIVATION OF DAMAGED PROTEINS Dawn A. Parsell, S Lindquist · Annual Review of Genetics | Dec 1993 | 2,228 |
| 17 | Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation Ana Carrizosa Anderson, Nicole Joller, Vijay Kumar Kuchroo · Immunity | May 2016 | 2,207 |
| 18 | STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology | 10 Jun 2005 | 2,133 |
| 19 | Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity Kaori Sakuishi, Lionel Apétoh, Jenna M. Sullivan et al. · The Journal of Experimental Medicine | 6 Sep 2010 | 2,106 |
| 20 | Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer Isabelle L. Ray-Coquard et al. · New England Journal of Medicine | 18 Dec 2019 | 2,104 |
| 21 | Discovering High-Affinity Ligands for Proteins: SAR by NMR Suzanne Beckham Shuker, Philip J. Hajduk, Robert P. Meadows et al. · Science | 29 Nov 1996 | 2,061 |
| 22 | Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast Joseph Heitman, N. Rao Movva, Michael N. Hall · Science | 23 Aug 1991 | 2,057 |
| 23 | RESPIRATORY SYNCYTIAL VIRUS DISEASE IN INFANTS DESPITE PRIOR ADMINISTRATION OF ANTIGENIC INACTIVATED VACCINE12 Hyun Wha Kim, Jose G. Canchola, Carl D. Brandt et al. · American Journal of Epidemiology | Apr 1969 | 2,029 |
| 24 | Thermal ablation of tumours: biological mechanisms and advances in therapy Katrina F. Chu, Damian Edward Dupuy · Nature reviews. Cancer | 24 Feb 2014 | 2,012 |
| 25 | Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis Beatrix Bartók, Gary S. Firestein · Immunological Reviews | 23 Dec 2009 | 1,947 |
| 26 | Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma Alice Lin-Tsing Yu, Andrew Lee Gilman, Mehmet Fevzi Ozkaynak et al. · New England Journal of Medicine | 29 Sep 2010 | 1,845 |
| 27 | Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions Damien D’Amours, Serge Desnoyers, Icy D’Silva et al. · Biochemical Journal | 24 Aug 1999 | 1,834 |
| 28 | Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin Bijan Zakeri, Jacob O. Fierer, Emrah Çelik et al. · Proceedings of the National Academy of Sciences | 24 Feb 2012 | 1,776 |
| 29 | Starch Gel Electrophoresis in a Discontinuous System of Buffers M. D. Poulik · Nature | Dec 1957 | 1,768 |
| 30 | Microneedles for drug and vaccine delivery Yeu‐Chun Kim, Jung‐Hwan Park, Mark R. Prausnitz · Advanced Drug Delivery Reviews | May 2012 | 1,758 |
| 31 | Induction by Antigen of Intrathymic Apoptosis of CD4 + CD8 + TCR lo Thymocytes in Vivo KENNETH M. M. MURPHY, Amy B. Heimberger, Dennis Y. Loh · Science | 21 Dec 1990 | 1,744 |
| 32 | Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis B. C. Trauth, Christiane Klas, Anke M. J. Peters et al. · Science | 21 Jul 1989 | 1,738 |
| 33 | Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. Roberto Manetti, Paola Parronchi, M G Giudizi et al. · The Journal of Experimental Medicine | Apr 1993 | 1,689 |
| 34 | The gasdermins, a protein family executing cell death and inflammation Petr Brož, Pablo Pelegrı́n, Feng Shao · Nature reviews. Immunology | 5 Nov 2019 | 1,684 |
| 35 | Plasmacytoid dendritic cells in immunity Marco Colonna, Giorgio Trinchieri, Yong‐Jun Liu · Nature Immunology | 17 Nov 2004 | 1,673 |
| 36 | Genome-Wide Analysis of NBS-LRR–Encoding Genes in Arabidopsis[W] Blake C. Meyers, Alexander Kozik, Alyssa Griego et al. · The Plant Cell | Apr 2003 | 1,659 |
| 37 | Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein Larry W. Moreland, Scott W. Baumgartner, Michael H. Schiff et al. · New England Journal of Medicine | 17 Jul 1997 | 1,650 |
| 38 | Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation Neil A. Clipstone, Gerald R. Crabtree · Nature | Jun 1992 | 1,648 |
| 39 | Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis William S. Hayward, Benjamin G. Neel, Susan M. Astrin · Nature | Apr 1981 | 1,593 |
| 40 | Exotoxins of Staphylococcus aureus Martin M. Dinges, Paul M. Orwin, Patrick M. Schlievert · Clinical Microbiology Reviews | 2000 | 1,586 |
| 41 | Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori John Christopher Atherton, Ping Cao, Richard M. Peek et al. · Journal of Biological Chemistry | Jul 1995 | 1,584 |
| 42 | THE IL-4 RECEPTOR: Signaling Mechanisms and Biologic Functions Keats A Nelms, Achsah Dorsey Keegan, José Luís Zamorano et al. · Annual Review of Immunology | Apr 1999 | 1,552 |
| 43 | RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs David M. Sabatini, Hediye Erdjument‐Bromage, Mary Lui et al. · Cell | Jul 1994 | 1,517 |
| 44 | Novel Signal Transduction Pathway Utilized by Extracellular HSP70 Alexzander A. A. Asea, Michael Rehli, Edith Kabingu et al. · Journal of Biological Chemistry | Apr 2002 | 1,510 |
| 45 | The c-erb-A gene encodes a thyroid hormone receptor Cary Weinberger, Catherine C. Thompson, Estelita S. Ong et al. · Nature | Dec 1986 | 1,498 |
| 46 | Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery William B. Pratt, David O. Toft · Experimental Biology and Medicine | Feb 2003 | 1,491 |
| 47 | Recombinant protein expression in Escherichia coli François Baneyx · Current Opinion in Biotechnology | Oct 1999 | 1,489 |
| 48 | Current status and future potential of transdermal drug delivery Mark R. Prausnitz, Samir Mitragotri, Róbert Langer · Nature Reviews Drug Discovery | 30 Jan 2004 | 1,476 |
| 49 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death Steven W. Muchmore, Michael Sattler, Heng Liang et al. · Nature | May 1996 | 1,475 |
| 50 | An hsp70-like protein in the ER: Identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein Sean Munro, Hugh R.B. Pelham · Cell | Jul 1986 | 1,474 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.