Most cited papers in vaccines and immunoinformatics approaches
What are the most cited papers in vaccines and immunoinformatics approaches?
The most cited paper in vaccines and immunoinformatics approaches is "Improved Survival with Ipilimumab in Patients with Metastatic Melanoma" (Frank Stephen Hodi et al., 2010), with 15,337 citations. Next come "Cancer immunoediting: from immunosurveillance to tumor escape" (5,415) and "A SARS-CoV-2 protein interaction map reveals targets for drug repurposing" (4,901).
Showing 50 of 100 papers. Every paper with more than 1,132 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Improved Survival with Ipilimumab in Patients with Metastatic Melanoma Frank Stephen Hodi et al. · New England Journal of Medicine | 5 Jun 2010 | 15,337 |
| 2 | Cancer immunoediting: from immunosurveillance to tumor escape Gavin P. Dunn, Allen T. Bruce, Hiroaki Ikeda et al. · Nature Immunology | 29 Oct 2002 | 5,415 |
| 3 | A SARS-CoV-2 protein interaction map reveals targets for drug repurposing David Ezra Gordon et al. · Nature | 30 Apr 2020 | 4,901 |
| 4 | The Dendritic Cell System and its Role in Immunogenicity Ralph M. Steinman · Annual Review of Immunology | Apr 1991 | 4,722 |
| 5 | Genome sequence of the human malaria parasite Plasmodium falciparum Malcolm J. Gardner et al. · Nature | Oct 2002 | 4,520 |
| 6 | Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma Alexandra Snyder et al. · New England Journal of Medicine | 20 Nov 2014 | 4,426 |
| 7 | Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies Robert E. W. Hancock, Hans‐Georg Sahl · Nature Biotechnology | Dec 2006 | 4,225 |
| 8 | Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals Alba Grifoni, Daniela Weiskopf, Sydney I. Ramirez et al. · Cell | 20 May 2020 | 4,054 |
| 9 | SARS-CoV-2 variants, spike mutations and immune escape William T. Harvey, Alessandro M. Carabelli, Ben Jackson et al. · Nature Reviews Microbiology | Jun 2021 | 3,930 |
| 10 | An mRNA Vaccine against SARS-CoV-2 — Preliminary Report Lisa A. Jackson et al. · New England Journal of Medicine | 14 Jul 2020 | 3,519 |
| 11 | Approaching the Asymptote? Evolution and Revolution in Immunology Charles A. Janeway · Cold Spring Harbor Symposia on Quantitative Biology | 1989 | 3,250 |
| 12 | VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines Irini Atanas Doytchinova, Darren R. Flower · BMC Bioinformatics | 5 Jan 2007 | 3,092 |
| 13 | A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology Andrew Rambaut, Edward Charles Holmes, Aine Niamh O’Toole et al. · Nature Microbiology | 15 Jul 2020 | 3,026 |
| 14 | An immunogenic personal neoantigen vaccine for patients with melanoma Patrick Alexander Ott et al. · Nature | 4 Jul 2017 | 3,022 |
| 15 | SignalP 6.0 predicts all five types of signal peptides using protein language models Felix Teufel, José Juan Almagro Armenteros, Alexander Rosenberg Johansen et al. · Nature Biotechnology | 3 Jan 2022 | 2,998 |
| 16 | Cancer immunotherapy: moving beyond current vaccines Steven A. Rosenberg, James Chih-Hsin Yang, Nicholas P. Restifo · Nature Medicine | 31 Aug 2004 | 2,983 |
| 17 | Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells Frank Oliver Nestle, Selma Alijagic, Michel F. Gilliet et al. · Nature Medicine | Mar 1998 | 2,892 |
| 18 | Comprehensive analyses of tumor immunity: implications for cancer immunotherapy Bo Li, Eric Allan Severson, Jean‐Christophe Pignon et al. · Genome biology | 22 Aug 2016 | 2,798 |
| 19 | Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype Recombination Kavita Satish Lole, Robert C. Bollinger, Ramesh Paranjape et al. · Journal of Virology | 1999 | 2,771 |
| 20 | A Landscape of Driver Mutations in Melanoma Eran Hodis et al. · Cell | Jul 2012 | 2,672 |
| 21 | TISIDB: an integrated repository portal for tumor–immune system interactions Beibei Ru, Ching Ngar Wong, Yin Tong et al. · Bioinformatics | 20 Mar 2019 | 2,668 |
| 22 | Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial Pedro M. Folegatti et al. · The Lancet | 20 Jul 2020 | 2,629 |
| 23 | A comprehensive map of molecular drug targets Rita Santos, Oleg Ursu, Anna Gaulton et al. · Nature Reviews Drug Discovery | 2 Dec 2016 | 2,546 |
| 24 | Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer Uğur Şahin et al. · Nature | 4 Jul 2017 | 2,536 |
| 25 | Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods Canrong Wu, Yang Liu, Yueying Yang et al. · Acta Pharmaceutica Sinica B | 27 Feb 2020 | 2,482 |
| 26 | NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data Birkir Reynisson, Bruno Alvarez, Sinu Paul et al. · Nucleic Acids Research | 29 Apr 2020 | 2,480 |
| 27 | SMART: recent updates, new developments and status in 2020 Ivica Letunić, Supriya Khedkar, Peer Bork · Nucleic Acids Research | 6 Oct 2020 | 2,404 |
| 28 | The Immune Epitope Database (IEDB): 2018 update Randi Vita, Swapnil Mahajan, James A. Overton et al. · Nucleic Acids Research | 11 Oct 2018 | 2,400 |
| 29 | SYFPEITHI: database for MHC ligands and peptide motifs Hans‐Georg Rammensee, Jutta Bachmann, Niels Emmerich et al. · Immunogenetics | 22 Nov 1999 | 2,342 |
| 30 | Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding Tyler N. Starr, Allison J. Greaney, Sarah K. Hilton et al. · Cell | 11 Aug 2020 | 2,267 |
| 31 | Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor Fang Li, Wenhui Li, Michael Reynolds Farzan et al. · Science | 15 Sep 2005 | 2,230 |
| 32 | ProteoWizard: open source software for rapid proteomics tools development Darren Kessner, Matt Chambers, Robert Burke et al. · Bioinformatics | 7 Jul 2008 | 2,142 |
| 33 | Batf3 Deficiency Reveals a Critical Role for CD8α + Dendritic Cells in Cytotoxic T Cell Immunity Kai Hildner, Brian T. Edelson, Whitney E. Purtha et al. · Science | 13 Nov 2008 | 2,093 |
| 34 | In Silico Approach for Predicting Toxicity of Peptides and Proteins Sudheer Gupta, Pallavi Kapoor, Kumardeep Chaudhary et al. · PLoS ONE | 13 Sep 2013 | 2,078 |
| 35 | CB-Dock2: improved protein–ligand blind docking by integrating cavity detection, docking and homologous template fitting Yang Liu, Xiaocong Yang, Jianhong Gan et al. · Nucleic Acids Research | 5 May 2022 | 2,067 |
| 36 | Designing antimicrobial peptides: form follows function Christopher D. Fjell, Jan A. Hiss, Robert E. W. Hancock et al. · Nature Reviews Drug Discovery | 16 Dec 2011 | 2,061 |
| 37 | Mapping the Antigenic and Genetic Evolution of Influenza Virus Derek J. Smith, Alan S. Lapedes, Jan C. de Jong et al. · Science | 24 Jun 2004 | 1,998 |
| 38 | Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa Raquel Pricilla e Silva Viana et al. · Nature | 7 Jan 2022 | 1,926 |
| 39 | Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis Xavier Montalbán et al. · New England Journal of Medicine | 21 Dec 2016 | 1,913 |
| 40 | MiXCR: software for comprehensive adaptive immunity profiling Dmitriy A. Bolotin, S. Poslavskii, Igor Mitrophanov et al. · Nature Methods | 29 Apr 2015 | 1,898 |
| 41 | Effector and memory T-cell differentiation: implications for vaccine development Susan M. Kaech, E. John Wherry, Rafi Ahmed · Nature reviews. Immunology | Apr 2002 | 1,892 |
| 42 | ZDOCK server: interactive docking prediction of protein–protein complexes and symmetric multimers Brian G. Pierce, Kevin J. Wiehe, Howook Hwang et al. · Bioinformatics | 14 Feb 2014 | 1,853 |
| 43 | BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes Martin Closter Jespersen, Bjoern Peters, Morten Nielsen et al. · Nucleic Acids Research | 20 Apr 2017 | 1,849 |
| 44 | The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum Zbynek Bozdech, Manuel Llinás, Brian Pulliam et al. · PLoS Biology | 18 Aug 2003 | 1,846 |
| 45 | Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells Frank James Hsu, Claudia J. Benike, Francesco Fausto Fagnoni et al. · Nature Medicine | 1996 | 1,840 |
| 46 | Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia Denis Y. Logunov et al. · The Lancet | Feb 2021 | 1,839 |
| 47 | Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma Steven A. Rosenberg, James Chih‐Hsin Yang, Douglas J. Schwartzentruber et al. · Nature Medicine | Mar 1998 | 1,808 |
| 48 | Prediction of continuous B‐cell epitopes in an antigen using recurrent neural network Sudipto Saha, Gajendra P. S. Raghava · Proteins Structure Function and Bioinformatics | 7 Aug 2006 | 1,801 |
| 49 | Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists Beili Wu, Ellen Y. T. Chien, Clifford D. Mol et al. · Science | 7 Oct 2010 | 1,800 |
| 50 | ElliPro: a new structure-based tool for the prediction of antibody epitopes Julia V. Ponomarenko, Huynh‐Hoa Bui, Wei Li et al. · BMC Bioinformatics | Dec 2008 | 1,787 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.