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Most cited papers in Xenotransplantation and immune response

Xenotransplantation and immune response

What are the most cited papers in Xenotransplantation and immune response?

The most cited paper in Xenotransplantation and immune response is "Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA" (ERIC A. JAFFE, Ralph L. Nachman, Carl G. Becker et al., 1973), with 6,923 citations. Next come "Cancer/testis antigens, gametogenesis and cancer" (1,613) and "NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells" (1,487).

Showing 50 of 100 papers. Every paper with more than 414 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA ERIC A. JAFFE, Ralph L. Nachman, Carl G. Becker et al. · Journal of Clinical Investigation Open access Nov 1973 6,923
2 Cancer/testis antigens, gametogenesis and cancer Andrew J.G. Simpson, Otávia L. Caballero, Achim A. Jungbluth et al. · Nature reviews. Cancer Review 20 Jul 2005 1,613
3 NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells Mamoru Ito, Hidefumi Hiramatsu, Kimio Kobayashi et al. · Blood 16 Oct 2002 1,487
4 Production of α-1,3-Galactosyltransferase Knockout Pigs by Nuclear Transfer Cloning Liangxue Lai, Donna Kolber‐Simonds, Kwang‐Wook Park et al. · Science 8 Feb 2002 1,344
5 Prostate cancer in a transgenic mouse. Norman M. Greenberg, Francesco John DeMayo, Milton J. Finegold et al. · Proceedings of the National Academy of Sciences Open access 11 Apr 1995 1,305
6 Humanized mice in translational biomedical research Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner · Nature reviews. Immunology Review 27 Jan 2007 1,280
7 A role for CD95 ligand in preventing graft rejection Donald Bellgrau, Daniel P. Gold, Helena P. Selawry et al. · Nature Oct 1995 1,170
8 Infection of human cells by an endogenous retrovirus of pigs Clive Patience, Yasuhiro Takeuchi, Robin A. Weiss · Nature Medicine Mar 1997 1,165
9 Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg Deborah J. Lenschow, Yijun Zeng, J. Richard Thistlethwaite et al. · Science 7 Aug 1992 1,133
10 Production of α1,3-Galactosyltransferase-Deficient Pigs Carol J. Phelps et al. · Science Open access 16 Jan 2003 1,116
11 Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Timothy J. McDonnell, Patricia Troncoso, Shawn M. Brisbay et al. · PubMed 15 Dec 1992 1,059
12 High Levels of Foreign Gene Expression in Hepatocytes after Tail Vein Injections of Naked Plasmid DNA G Zhang, Vladimir G. Budker, Jon A. Wolff · Human Gene Therapy Jul 1999 952
13 Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. Thomas A. Rando, Helen M. Blau · The Journal of Cell Biology Open access 15 Jun 1994 948
14 Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells. Uri Galili, Simon Shohet, E Kobrin et al. · Journal of Biological Chemistry Open access Nov 1988 948
15 A complex between prostate-specific antigen and alpha 1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: assay of the complex improves clinical sensitivity for cancer. Ulf‐Håkan Stenman, Jari Leinonen, Henrik V. Alfthan et al. · PubMed 1991 939
16 Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells Beverly H. Koller, Philippa Marrack, John W. Kappler et al. · Science 8 Jun 1990 887
17 "Infectious" Transplantation Tolerance Shixin Qin, Stephen Paul Cobbold, Heather Pope et al. · Science 12 Feb 1993 881
18 Importance of the pig as a human biomedical model Joan K. Lunney, Angelica Van Goor, Kristen Walker et al. · Science Translational Medicine 24 Nov 2021 854
19 Immune response to biologic scaffold materials Stephen F. Badylak, Thomas W. Gilbert · Seminars in Immunology Open access 13 Mar 2008 852
20 Induction of Immunological Tolerance by Porcine Liver Allografts R. Y. Calne, Robert A. Sells, J Peña et al. · Nature Aug 1969 846
21 Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance Thomas E. Starzl, Anthony J. Demetris, Massimo Trucco et al. · Hepatology Open access Jun 1993 812
22 Immunologically Privileged Sites Clyde F. Barker, Rupert Everett Billingham · Advances in immunology Book chapter 1978 812
23 PRIMARILY VASCULARIZED ALLOGRAFTS OF HEARTS IN MICE Robert J. Corry, Henry J. Winn, Paul S. Russell · Transplantation Oct 1973 794
24 Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 Dong Niu et al. · Science Open access 10 Aug 2017 777
25 Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts Suzanne T. Ildstad, David H. Sachs · Nature 1984 758
26 A luminal epithelial stem cell that is a cell of origin for prostate cancer Xi Wang, Marianna Kruithof‐de Julio, Kyriakos D. Economides et al. · Nature Open access Sep 2009 748
27 Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures Wouter R. Karthaus, Phillip J. Iaquinta, Jarno Drost et al. · Cell Open access Sep 2014 746
28 Xenogeneic extracellular matrix as a scaffold for tissue reconstruction Stephen F. Badylak · Transplant Immunology 17 Feb 2004 738
29 Natural autoantibodies: from ‘horror autotoxicus’ to ‘gnothi seauton’ Stratis Avraméas · Immunology Today 1991 738
30 Search for Cross-Species Transmission of Porcine Endogenous Retrovirus in Patients Treated with Living Pig Tissue Khazal Paradis, Gillian A. Langford, Zhifeng Long et al. · Science 20 Aug 1999 736
31 An Envelope Glycoprotein of the Human Endogenous Retrovirus HERV-W Is Expressed in the Human Placenta and Fuses Cells Expressing the Type D Mammalian Retrovirus Receptor Jean-Luc Blond, Dimitri Lavillette, Valérie Cheynet et al. · Journal of Virology Open access Apr 2000 727
32 Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs Yifan Dai, Todd D. Vaught, Jeremy T. Boone et al. · Nature Biotechnology Mar 2002 714
33 Genetically Modified Porcine-to-Human Cardiac Xenotransplantation Bartley P. Griffith, Corbin E. Goerlich, Avneesh Kumar Singh et al. · New England Journal of Medicine Open access 22 Jun 2022 708
34 VEGF Gene Delivery to Myocardium Randall J. Lee, Matthew L. Springer, William E. Blanco-Bose et al. · Circulation 22 Aug 2000 700
35 Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experience Kenji Kuwaki et al. · Nature Medicine 26 Dec 2004 697
36 Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer Robert Evan Reiter, Zhennen Gu, Tetsuro Watabe et al. · Proceedings of the National Academy of Sciences Open access 17 Feb 1998 688
37 HGF/SF Is Present in Normal Adult Skeletal Muscle and Is Capable of Activating Satellite Cells Ryuichi Tatsumi, Judy E. Anderson, Cedrine J. Nevoret et al. · Developmental Biology Open access Feb 1998 681
38 CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE Graham F. Mitchell, JACQUES F. A. P. MILLER · The Journal of Experimental Medicine Open access Oct 1968 672
39 Interaction of the natural anti-Gal antibody with α-galactosyl epitopes: a major obstacle for xenotransplantation in humans Uri Galili · Immunology Today Oct 1993 662
40 Optimization of chemically defined cell culture media – Replacing fetal bovine serum in mammalian in vitro methods Jan M. A. van der Valk, Daniel L. Brunner, Karen De Smet et al. · Toxicology in Vitro Open access Apr 2010 655
41 B-cell-derived lymphotoxin promotes castration-resistant prostate cancer Massimo Ammirante, Jun‐Li Luo, Sergei I. Grivennikov et al. · Nature Open access 9 Mar 2010 650
42 CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE JACQUES F. A. P. MILLER, G.F. Mitchell · The Journal of Experimental Medicine Open access Oct 1968 646
43 Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. A.H. Good, D. K. C. Cooper, Andrew J. Malcolm et al. · PubMed Apr 1992 641
44 Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. Yehonatan Sharabi, David H. Sachs · The Journal of Experimental Medicine Open access Feb 1989 634
45 Genome-wide inactivation of porcine endogenous retroviruses (PERVs) Luhan Yang, Marc Güell, Dong Niu et al. · Science Open access 12 Oct 2015 629
46 Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid Pam Tangvoranuntakul, Pascal Gagneux, Sandra L. Diaz et al. · Proceedings of the National Academy of Sciences Open access Oct 2003 629
47 Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue Kazuhiko Yamada, Koji Yazawa, Akira Shimizu et al. · Nature Medicine 26 Dec 2004 614
48 Thymus-Marrow Cell Combinations. Synergism in Antibody Production. Henry N. Claman, Edward A. Chaperon, R. Faser Triplett · Experimental Biology and Medicine Aug 1966 612
49 Maintenance Dialysis Population Dynamics Michael J. Lysaght · Journal of the American Society of Nephrology 2002 610
50 Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes. Mauro S. Sandrin, H Vaughan, Paul Dabkowski et al. · Proceedings of the National Academy of Sciences Open access Dec 1993 610

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.