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Most cited papers from Children's Hospital

What are the most cited papers from Children's Hospital?

The most cited paper from Children's Hospital is "Genome-wide maps of chromatin state in pluripotent and lineage-committed cells" (Tarjei S. Mikkelsen et al., 2007), with 4,237 citations. Next come "Maternal Thyroid Deficiency during Pregnancy and Subsequent Neuropsychological Development of the Child" (2,587) and "A Potential Decline in Life Expectancy in the United States in the 21st Century" (2,536).

Showing 50 of 59 papers. Every paper with more than 453 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Genome-wide maps of chromatin state in pluripotent and lineage-committed cells Tarjei S. Mikkelsen et al. · Nature Open access Jul 2007 4,237
2 Maternal Thyroid Deficiency during Pregnancy and Subsequent Neuropsychological Development of the Child James E. Haddow, Glenn E. Palomaki, Walter C. Allan et al. · New England Journal of Medicine Open access 19 Aug 1999 2,587
3 A Potential Decline in Life Expectancy in the United States in the 21st Century S. Jay Olshansky, Douglas J. Passaro, Ronald C. Hershow et al. · New England Journal of Medicine Open access 17 Mar 2005 2,536
4 A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds Stuart A. Lipton, Yun‐Beom Choi, Zhuo‐Hua Pan et al. · Nature Aug 1993 2,449
5 Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report Joshua A. Boyce et al. · Journal of Allergy and Clinical Immunology Open access Dec 2010 2,352
6 The revised Ghent nosology for the Marfan syndrome: Table 1 Bart Loeys, Harry C. Dietz, Alan C. Braverman et al. · Journal of Medical Genetics Open access 30 Jun 2010 2,253
7 A brain-specific microRNA regulates dendritic spine development Gerhard M. Schratt, Fabian Tuebing, Elizabeth A. Nigh et al. · Nature 19 Jan 2006 1,806
8 Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 Andrei V. Krivtsov, David Twomey, Zhaohui Feng et al. · Nature 16 Jul 2006 1,551
9 Compensation mechanism in tumor cell migration Katarina Wolf, Irina B. Mazo, Harry C. H. Leung et al. · The Journal of Cell Biology Open access 13 Jan 2003 1,399
10 Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth Donald E. Ingber, Takeshi Fujita, SHOJI KISHIMOTO et al. · Nature Dec 1990 1,306
11 Increased Vascular Endothelial Growth Factor Levels in the Vitreous of Eyes With Proliferative Diabetic Retinopathy Anthony P. Adamis, Joan W. Miller, Teresa Bernal et al. · American Journal of Ophthalmology Oct 1994 1,300
12 Graft-versus-Host Disease James L.M. Ferrara, H. Joachim Deeg · New England Journal of Medicine 7 Mar 1991 1,240
13 Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women Jennifer K. Pai, Tobias Pischon, Jing Ma et al. · New England Journal of Medicine Open access 15 Dec 2004 1,180
14 LKB1 modulates lung cancer differentiation and metastasis Hongbin Ji et al. · Nature 5 Aug 2007 1,085
15 Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway Seija Lehnardt, Leon J. Massillon, Pamela L. Follett et al. · Proceedings of the National Academy of Sciences Open access 24 Jun 2003 1,069
16 Clinical Validation and Guidelines for the SCORAD Index: Consensus Report of the European Task Force on Atopic Dermatitis Barbara Kunz, A. P. Oranje, Laurent Labreze et al. · Dermatology 6 Oct 2009 1,053
17 Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey Adit A. Ginde, Jonathan M. Mansbach, Carlos A. Camargo · Archives of Internal Medicine Open access 23 Feb 2009 1,020
18 A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease Klaus Lindpaintner, Marc Alan Pfeffer, Reinhold Kreutz et al. · New England Journal of Medicine Open access 16 Mar 1995 911
19 Neonatal-Onset Multisystem Inflammatory Disease Responsive to Interleukin-1β Inhibition Raphaela Goldbach‐Mansky et al. · New England Journal of Medicine Open access 9 Aug 2006 908
20 American College of Radiology White Paper on Radiation Dose in Medicine Edward S. Amis, Priscilla F. Butler, Kimberly E. Applegate et al. · Journal of the American College of Radiology Open access 30 Apr 2007 903
21 EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast Ingeborg Margrethe Bachmann, OLE JOHAN HALVORSEN, Karin Collett et al. · Journal of Clinical Oncology 6 Dec 2005 861
22 Adaptive immunity Francisco A. Bonilla, Hans C. Oettgen · Journal of Allergy and Clinical Immunology 13 Jan 2010 832
23 The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice Mohammed Javeed Ansari, Alan David Salama, Tanuja Chitnis et al. · The Journal of Experimental Medicine Open access 7 Jul 2003 820
24 Female Sex and Higher Drug Dose as Risk Factors for Late Cardiotoxic Effects of Doxorubicin Therapy for Childhood Cancer Steven E. Lipshultz, Stuart R. Lipsitz, Suzanne M. Mone et al. · New England Journal of Medicine Open access 29 Jun 1995 816
25 Developmental and Neurologic Status of Children after Heart Surgery with Hypothermic Circulatory Arrest or Low-Flow Cardiopulmonary Bypass David C. Bellinger, Richard A. Jonas, Leonard Rappaport et al. · New England Journal of Medicine 2 Mar 1995 814
26 Effect of VX-770 in Persons with Cystic Fibrosis and the G551D- CFTR Mutation Frank J. Accurso et al. · New England Journal of Medicine Open access 17 Nov 2010 807
27 Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone Stefan Rutkowski, Udo F. W. Bode, Frank Deinlein et al. · New England Journal of Medicine Open access 9 Mar 2005 758
28 Tight junction defects in patients with atopic dermatitis Anna De Benedetto et al. · Journal of Allergy and Clinical Immunology Open access 16 Dec 2010 747
29 Psychosocial Risk Factors Associated With Cyberbullying Among Adolescents André Sourander, Anat Brunstein Klomek, Maria Ikonen et al. · Archives of General Psychiatry Jul 2010 735
30 Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events Sekar Kathiresan, Olle Melander, Dragi Anevski et al. · New England Journal of Medicine Open access 19 Mar 2008 719
31 Intracytoplasmic Sperm Injection May Increase the Risk of Imprinting Defects Gerald F. Cox, Joachim Bürger, Va Lip et al. · The American Journal of Human Genetics Open access Jul 2002 709
32 A Comparison of the Perioperative Neurologic Effects of Hypothermic Circulatory Arrest versus Low-Flow Cardiopulmonary Bypass in Infant Heart Surgery Jane W. Newburger, Richard A. Jonas, Gil Wernovsky et al. · New England Journal of Medicine 7 Oct 1993 707
33 Effect of Anti-IgE Therapy in Patients with Peanut Allergy Donald Y.M. Leung, Hugh A. Sampson, John W. Yunginger et al. · New England Journal of Medicine Open access 13 Mar 2003 696
34 Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways D. Woodrow Benson, G. Michael Silberbach, Ann L. Kavanaugh-McHugh et al. · Journal of Clinical Investigation Open access Dec 1999 694
35 Dose of Prophylactic Platelet Transfusions and Prevention of Hemorrhage Sherrill J. Slichter et al. · New England Journal of Medicine Open access 17 Feb 2010 674
36 Long-term outcome in congenitally corrected transposition of the great arteries T.P. Graham et al. · Journal of the American College of Cardiology Open access Jul 2000 672
37 Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Masayuki P. Yamamoto, L J Ko, Meghan Leonard et al. · Genes & Development Open access Oct 1990 625
38 Factors associated with impaired clinical status in long-term survivors of tetralogy of Fallot repair evaluated by magnetic resonance imaging Tal Geva, Bryan M. Sandweiss, Kimberlee Gauvreau et al. · Journal of the American College of Cardiology Open access Mar 2004 624
39 Lens Injury Stimulates Axon Regeneration in the Mature Rat Optic Nerve Steven P. Leon, Yuqin Yin, Jennifer T. Nguyen et al. · Journal of Neuroscience Open access 15 Jun 2000 620
40 PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome Deborah J. Marsh et al. · Human Molecular Genetics Aug 1999 617
41 Comparative Effectiveness of Revascularization Strategies William S. Weintraub et al. · New England Journal of Medicine Open access 27 Mar 2012 613
42 Optimal clinical management of children receiving the ketogenic diet: Recommendations of the International Ketogenic Diet Study Group Eric H. Kossoff et al. · Epilepsia Open access 24 Sep 2008 610
43 IgH class switching and translocations use a robust non-classical end-joining pathway Catherine T. Yan, Cristian Boboilă, Ellen Kris Souza et al. · Nature 22 Aug 2007 593
44 Angelman and Prader‐Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion Joan H.M. Knoll, Robert D. Nicholls, R.E. Magenis et al. · American Journal of Medical Genetics Feb 1989 586
45 Enzyme-Replacement Therapy in Life-Threatening Hypophosphatasia Michael P. Whyte et al. · New England Journal of Medicine Open access 7 Mar 2012 572
46 Burst abdomen and incisional hernia: a prospective study of 1129 major laparotomies. Timothy E. Bucknall, Pablo Cox, Harold Ellis · BMJ Open access 27 Mar 1982 559
47 Hyponatremia among Runners in the Boston Marathon Christopher S.D. Almond, Andrew Young Shin, Elizabeth B. Fortescue et al. · New England Journal of Medicine Open access 13 Apr 2005 555
48 Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. O Platt, Stuart H. Orkin, G Dover et al. · Journal of Clinical Investigation Open access Aug 1984 538
49 Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells Hanno R. Hock, Melanie J. Hamblen, Heather M. Rooke et al. · Nature 29 Sep 2004 537
50 Structure, development, and plasticity of dendritic spines Kristen M. Harris · Current Opinion in Neurobiology Review Jun 1999 528

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.