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Most cited papers from Clinical Evaluation Research Unit

Clinical Evaluation Research Unit

What are the most cited papers from Clinical Evaluation Research Unit?

The most cited paper from Clinical Evaluation Research Unit is "Defining Advance Care Planning for Adults: A Consensus Definition From a Multidisciplinary Delphi Panel" (Rebecca L. Sudore, Hillary D. Lum, John J. You et al., 2017), with 1,763 citations. Next come "The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study" (983) and "Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool" (878).

Showing 50 of 60 papers. Every paper with more than 118 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Defining Advance Care Planning for Adults: A Consensus Definition From a Multidisciplinary Delphi Panel Rebecca L. Sudore, Hillary D. Lum, John J. You et al. · Journal of Pain and Symptom Management Open access 5 Jan 2017 1,763
2 The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study Cathy Alberda, Leah M Gramlich, N. F. Jones et al. · Intensive Care Medicine Jul 2009 983
3 Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool Daren Keith Heyland, Rupinder Dhaliwal, Xuran Jiang et al. · Critical Care Open access 15 Nov 2011 878
4 Identifying critically-ill patients who will benefit most from nutritional therapy: Further validation of the “modified NUTRIC” nutritional risk assessment tool Adam Rahman, Rana M. Hasan, Ravi Agarwala et al. · Clinical Nutrition 27 Jan 2015 537
5 Failure to Engage Hospitalized Elderly Patients and Their Families in Advance Care Planning Daren Keith Heyland · JAMA Internal Medicine Apr 2013 509
6 Extreme Dysbiosis of the Microbiome in Critical Illness Daniel T. McDonald, Gail L. Ackermann, Ludmila S. Khailova et al. · mSphere Open access 31 Aug 2016 440
7 Barriers to Goals of Care Discussions With Seriously Ill Hospitalized Patients and Their Families John J. You et al. · JAMA Internal Medicine 2 Feb 2015 426
8 Metabolic and nutritional support of critically ill patients: consensus and controversies Jean‐Charles Preiser, Arthur R. H. van Zanten, Mette M. Berger et al. · Critical Care Open access 28 Jan 2015 419
9 The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial Daren Keith Heyland, Jayshil J. Patel, Charlene W. Compher et al. · The Lancet 25 Jan 2023 391
10 Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials Gunnar Elke, Arthur R. H. van Zanten, Margot Lemieux et al. · Critical Care ReviewOpen access 29 Apr 2016 388
11 Outcomes That Define Successful Advance Care Planning: A Delphi Panel Consensus Rebecca L. Sudore, Daren Keith Heyland, Hillary D. Lum et al. · Journal of Pain and Symptom Management Open access Sep 2017 367
12 Perioperative Use of Arginine-supplemented Diets: A Systematic Review of the Evidence John Drover, Rupinder Dhaliwal, Lindsay B. Weitzel et al. · Journal of the American College of Surgeons 18 Jan 2011 353
13 Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: A systematic review and meta-analysis* John Muscedere, Oleksa Rewa, Kyle McKechnie et al. · Critical Care Medicine Review 10 Apr 2011 314
14 Optimal amount of calories for critically ill patients: Depends on how you slice the cake!* Daren Keith Heyland, Naomi E. Cahill, Andrew G. Day · Critical Care Medicine 25 Jun 2011 303
15 Prevalence, Risk Factors, Clinical Consequences, and Treatment of Enteral Feed Intolerance During Critical Illness Usha Gungabissoon, Kimberley E. Hacquoil, Chanchal Bains et al. · Journal of Parenteral and Enteral Nutrition 17 Mar 2014 302
16 Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis William Manzanares, Margot Lemieux, Pascal L. Langlois et al. · Critical Care ReviewOpen access 18 Aug 2016 300
17 Clinical Outcomes Related to Protein Delivery in a Critically Ill Population Michele Nicolò, Daren Keith Heyland, Jesse L. Chittams et al. · Journal of Parenteral and Enteral Nutrition 21 Apr 2015 300
18 Implications of low muscle mass across the continuum of care: a narrative review Carla Marques Maia Prado, Sarah A. Purcell, Carolyn J. Alish et al. · Annals of Medicine ReviewOpen access 31 Aug 2018 285
19 The Canadian Critical Care Nutrition Guidelines in 2013 Rupinder Dhaliwal, Naomi E. Cahill, Margot Lemieux et al. · Nutrition in Clinical Practice 2 Dec 2013 285
20 Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study Daren Keith Heyland, Allan Garland, Sean M. Bagshaw et al. · Intensive Care Medicine 25 Aug 2015 283
21 Greater Protein and Energy Intake May Be Associated With Improved Mortality in Higher Risk Critically Ill Patients: A Multicenter, Multinational Observational Study* Charlene W. Compher, Jesse L. Chittams, Therese E. Sammarco et al. · Critical Care Medicine 18 Jan 2017 273
22 Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock Frank Bloos et al. · JAMA Internal Medicine 18 Jul 2016 269
23 Measuring Advance Care Planning: Optimizing the Advance Care Planning Engagement Survey Rebecca L. Sudore, Daren Keith Heyland, Deborah E. Barnes et al. · Journal of Pain and Symptom Management Open access 29 Dec 2016 251
24 Higher versus lower blood pressure targets for vasopressor therapy in shock: a multicentre pilot randomized controlled trial for the Canadian Critical Care Trials Group. et al. · Intensive Care Medicine 18 Feb 2016 251
25 Close to recommended caloric and protein intake by enteral nutrition is associated with better clinical outcome of critically ill septic patients: secondary analysis of a large international nutrition database Gunnar Elke, Miao Wang, Norbert Weiler et al. · Critical Care Open access 10 Feb 2014 239
26 Antioxidant micronutrients in the critically ill: a systematic review and meta-analysis William Manzanares, Rupinder Dhaliwal, Xuran Jiang et al. · Critical Care ReviewOpen access 25 Apr 2012 233
27 Mortality, Attributable Mortality, and Clinical Events as End Points for Clinical Trials of Ventilator‐Associated Pneumonia and Hospital‐Acquired Pneumonia John Muscedere, Andrew G. Day, Daren Keith Heyland · Clinical Infectious Diseases 2 Jul 2010 231
28 Incidence, Risk Factors, and Clinical Consequence of Enteral Feeding Intolerance in the Mechanically Ventilated Critically Ill: An Analysis of a Multicenter, Multiyear Database Daren Keith Heyland, Alfonso Ortiz, Christian Stoppe et al. · Critical Care Medicine 4 Nov 2020 223
29 The prevalence of iatrogenic underfeeding in the nutritionally ‘at-risk’ critically ill patient: Results of an international, multicenter, prospective study Daren Keith Heyland, Rupinder Dhaliwal, Miao Wang et al. · Clinical Nutrition 19 Jul 2014 219
30 Procalcitonin for reduced antibiotic exposure in the critical care setting: A systematic review and an economic evaluation* Daren Keith Heyland, Ana P Johnson, Steven Reynolds et al. · Critical Care Medicine Review 25 Feb 2011 213
31 The Very Elderly Admitted to ICU Daren Keith Heyland, Deborah Cook, Sean M. Bagshaw et al. · Critical Care Medicine 22 Apr 2015 202
32 The Association Between Nutritional Adequacy and Long-Term Outcomes in Critically Ill Patients Requiring Prolonged Mechanical Ventilation Xuejiao Shelly Wei, Andrew G. Day, Helene M. J. Ouellette-Kuntz et al. · Critical Care Medicine 9 Apr 2015 188
33 Extreme Obesity and Outcomes in Critically Ill Patients Jenny L. Martino, Renee D. Stapleton, Miao Wang et al. · CHEST Journal Open access 5 Aug 2011 185
34 Enhanced protein-energy provision via the enteral route in critically ill patients: a single center feasibility trial of the PEP uP protocol Daren Keith Heyland, Naomi E. Cahill, Rupinder Dhaliwal et al. · Critical Care Open access 29 Apr 2010 183
35 Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol in Critically Ill Patients Daren Keith Heyland, Lauren Murch, Naomi E. Cahill et al. · Critical Care Medicine 27 Aug 2013 179
36 Parenteral glutamine supplementation in critical illness: a systematic review Paul Edmund Wischmeyer, Rupinder Dhaliwal, Michele McCall et al. · Critical Care ReviewOpen access 18 Apr 2014 176
37 ‘Not yet’ and ‘Just ask’: barriers and facilitators to advance care planning—a qualitative descriptive study of the perspectives of seriously ill, older patients and their families Jessica E. Simon, Pat Porterfield, Shelley Raffin Bouchal et al. · BMJ Supportive & Palliative Care Open access 19 Nov 2013 173
38 Validation of Bedside Ultrasound of Muscle Layer Thickness of the Quadriceps in the Critically Ill Patient (VALIDUM Study) Michael T. Paris, Marina Mourtzakis, Andrew G. Day et al. · Journal of Parenteral and Enteral Nutrition 9 Mar 2016 171
39 Gastric Residual Volume in Critically Ill Patients Gunnar Elke, Thomas W. Felbinger, Daren Keith Heyland · Nutrition in Clinical Practice 18 Dec 2014 166
40 A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial Paul Edmund Wischmeyer, Michel Hasselmann, Christine Kummerlen et al. · Critical Care Open access 9 Jun 2017 157
41 REducing Deaths due to OXidative Stress (The REDOXS© Study): rationale and study design for a randomized trial of glutamine and antioxidant supplementation in critically-ill patients Daren Keith Heyland, Rupinder Dhaliwal, Andrew G. Day et al. · Proceedings of The Nutrition Society Open access Aug 2006 154
42 Relationship of Vitamin D Deficiency to Clinical Outcomes in Critically Ill Patients David M. Higgins, Paul Edmund Wischmeyer, Kelly M. Queensland et al. · Journal of Parenteral and Enteral Nutrition 20 Apr 2012 153
43 Ventilator-associated pneumonia caused by multidrug-resistant organisms or Pseudomonas aeruginosa: Prevalence, incidence, risk factors, and outcomes Chris M. Parker, Jim Kutsogiannis, John Muscedere et al. · Journal of Critical Care Mar 2008 151
44 The effect of higher versus lower protein delivery in critically ill patients: a systematic review and meta-analysis of randomized controlled trials Zheng‐Yii Lee, Cindy Sing Ling Yap, Mohd Shahnaz Hasan et al. · Critical Care ReviewOpen access 23 Jul 2021 149
45 Impact of Enteral Feeding Protocols on Enteral Nutrition Delivery Daren Keith Heyland, Naomi E. Cahill, Rupinder Dhaliwal et al. · Journal of Parenteral and Enteral Nutrition Nov 2010 147
46 Measuring the quality of life of people at the end of life: The McGill Quality of Life Questionnaire–Revised S. Robin Cohen, Richard G. Sawatzky, Lara B. Russell et al. · Palliative Medicine 14 Jul 2016 145
47 Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials Mette M. Berger, Philippe Eggimann, Daren Keith Heyland et al. · Critical Care Open access 2 Nov 2006 145
48 Zinc Supplementation in Critically Ill Patients: A Key Pharmaconutrient? Daren Keith Heyland, N. F. Jones, Natalie Z. Cvijanovich et al. · Journal of Parenteral and Enteral Nutrition Open access 31 Jul 2008 145
49 Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery Christian Stoppe et al. · Critical Care Open access 5 Jun 2017 140
50 Pharmaconutrition: a new emerging paradigm Naomi E. Jones, Daren Keith Heyland · Current Opinion in Gastroenterology 12 Feb 2008 137

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.