Question 1

Who are the top researchers at Open Targets?

Accepted Answer

Ranked on the quality score, Maya Ghoussaini and Mohd Anisul Karim lead among researchers whose main affiliation is Open Targets.

Question 2

What are the most cited papers from Open Targets?

Accepted Answer

The most cited paper from Open Targets is "COSMIC: the Catalogue Of Somatic Mutations In Cancer" (John G. Tate et al., 2018), with 5,379 citations. Next come "The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019" (4,675) and "Applications of machine learning in drug discovery and development" (3,274).

Question 3

Which research topics does Open Targets publish most on?

Accepted Answer

By volume in 2022-now: Bioinformatics and Genomic Networks, CRISPR and Genetic Engineering, Computational Drug Discovery Methods and Single-cell and spatial transcriptomics.

Question 4

Which keywords describe research at Open Targets?

Accepted Answer

By fractional works in 2022-now, weighted toward what it does more of than the world: Gene Expression, Gene Set Enrichment Analysis, Protein-Protein Interaction Networks, Pharmacokinetics, RNA-Seq, Data Integration, Medicinal Chemistry and Genome Engineering.

Question 5

Which fields of science does Open Targets work in?

Accepted Answer

In 2022-now, 61% of research at Open Targets is in Life Sciences, 20% in Health Sciences. Its largest fields are Biochemistry, Genetics and Molecular Biology (49%), Medicine (19%), Immunology and Microbiology (8%). It does 2.9× the world's share of Life Sciences.

Question 6

Is Open Targets's research output growing?

Accepted Answer

Output in 2022-2025 was 48% higher than in 2018-2021.

Discussion