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Research facility · Cambridge · United Kingdom

Open Targets

opentargets.orgROR OpenAlex
Research works
61
▲ 48% vs 2018-21
Citations
11k
182.3 per fractional work
Top-10% rate
31.2%
all institutions 10.0%
Open access
79%
world 40%
International
57%
world 18%
Open Targets

Not ranked overall: Open Targets is under the volume floor below which an excellence rate is noise. Not ranked is not the same as ranked last.

Which fields of science does Open Targets work in?

In 2022-now, 61% of research at Open Targets is in Life Sciences, 20% in Health Sciences. Its largest fields are Biochemistry, Genetics and Molecular Biology (49%), Medicine (19%), Immunology and Microbiology (8%). It does 2.9× the world's share of Life Sciences.

Life Sciences: 16 fractional works · 61.2% of its workBiochemistry, Genetics and Molecular Biology: 13 fractional works · 49.1% of its workMolecular Biology: 9 fractional works · 33.8% of its workGenetics: 3 fractional works · 9.9% of its workCancer Research: 1 fractional works · 3.0% of its workBiophysics: 0 fractional works · 1.4% of its workCell Biology: 0 fractional works · 1.0% of its workImmunology and Microbiology: 2 fractional works · 7.7% of its workImmunology: 2 fractional works · 7.7% of its workNeuroscience: 1 fractional works · 2.8% of its workNeurology: 0 fractional works · 1.9% of its workCellular and Molecular Neuroscience: 0 fractional works · 0.4% of its workSensory Systems: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.2% of its workPharmacology, Toxicology and Pharmaceutics: 0 fractional works · 0.9% of its workPharmacology: 0 fractional works · 0.9% of its workAgricultural and Biological Sciences: 0 fractional works · 0.6% of its workPlant Science: 0 fractional works · 0.6% of its workHealth Sciences: 5 fractional works · 19.9% of its workMedicine: 5 fractional works · 19.3% of its workOncology: 2 fractional works · 5.8% of its workPulmonary and Respiratory Medicine: 0 fractional works · 1.8% of its workPhysiology: 0 fractional works · 1.7% of its workPublic Health, Environmental and Occupational Health: 0 fractional works · 1.4% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 1.3% of its workRadiology, Nuclear Medicine and Imaging: 0 fractional works · 1.0% of its workCardiology and Cardiovascular Medicine: 0 fractional works · 0.8% of its workReproductive Medicine: 0 fractional works · 0.8% of its workNeurology: 0 fractional works · 0.8% of its workRheumatology: 0 fractional works · 0.7% of its workEpidemiology: 0 fractional works · 0.6% of its workPediatrics, Perinatology and Child Health: 0 fractional works · 0.4% of its workHealth Informatics: 0 fractional works · 0.4% of its workHepatology: 0 fractional works · 0.4% of its workInfectious Diseases: 0 fractional works · 0.3% of its workNephrology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.9% of its workNursing: 0 fractional works · 0.5% of its workNutrition and Dietetics: 0 fractional works · 0.3% of its workResearch and Theory: 0 fractional works · 0.2% of its workHealth Professions: 0 fractional works · 0.2% of its workPhysical Sciences: 3 fractional works · 12.7% of its workComputer Science: 2 fractional works · 5.9% of its workComputational Theory and Mathematics: 1 fractional works · 4.7% of its workArtificial Intelligence: 0 fractional works · 0.6% of its workInformation Systems: 0 fractional works · 0.6% of its workChemistry: 1 fractional works · 2.6% of its workSpectroscopy: 0 fractional works · 1.8% of its workOrganic Chemistry: 0 fractional works · 0.4% of its workPhysical and Theoretical Chemistry: 0 fractional works · 0.4% of its workEnergy: 0 fractional works · 0.8% of its workRenewable Energy, Sustainability and the Environment: 0 fractional works · 0.8% of its workPhysics and Astronomy: 0 fractional works · 0.8% of its workAtomic and Molecular Physics, and Optics: 0 fractional works · 0.4% of its workStatistical and Nonlinear Physics: 0 fractional works · 0.4% of its workEngineering: 0 fractional works · 0.8% of its workBiomedical Engineering: 0 fractional works · 0.8% of its workEnvironmental Science: 0 fractional works · 0.7% of its workPollution: 0 fractional works · 0.4% of its workEnvironmental Chemistry: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workMathematics: 0 fractional works · 0.7% of its workStatistics and Probability: 0 fractional works · 0.7% of its workEarth and Planetary Sciences: 0 fractional works · 0.3% of its workGeology: 0 fractional works · 0.3% of its workSocial Sciences: 2 fractional works · 6.2% of its workEconomics, Econometrics and Finance: 1 fractional works · 4.6% of its workEconomics and Econometrics: 1 fractional works · 2.7% of its workFinance: 0 fractional works · 1.9% of its workDecision Sciences: 0 fractional works · 1.0% of its workInformation Systems and Management: 0 fractional works · 1.0% of its workArts and Humanities: 0 fractional works · 0.3% of its workArcheology: 0 fractional works · 0.3% of its workSocial Sciences: 0 fractional works · 0.2% of its workEducation: 0 fractional works · 0.2% of its workALL ITS WORKOpen Targets26fractional works, 2022-now
Life Sciences61%Physical Sciences13%Health Sciences20%Social Sciences6%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 20 fields, with their numbers
    1. Biochemistry, Genetics and Molecular Biology1349.1%
    2. Immunology and Microbiology27.7%
    3. Neuroscience12.8%
    4. Pharmacology, Toxicology and Pharmaceutics00.9%
    5. Agricultural and Biological Sciences00.6%
    1. Medicine519.3%
    2. Nursing00.5%
    3. Health Professions00.2%
    1. Computer Science25.9%
    2. Chemistry12.6%
    3. Energy00.8%
    4. Physics and Astronomy00.8%
    5. Engineering00.8%
    6. Environmental Science00.7%
    7. Mathematics00.7%
    8. Earth and Planetary Sciences00.3%
    1. Economics, Econometrics and Finance14.6%
    2. Decision Sciences01.0%
    3. Arts and Humanities00.3%
    4. Social Sciences00.2%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 0.13× its world share, 0 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 9.21× its world share, 13 worksBiochemistry, Geneti…Immunology and Microbiology: 7.69× its world share, 2 worksImmunology and Micro…Neuroscience: 1.70× its world share, 1 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 2.61× its world share, 0 worksPharmacology, Toxico…Chemistry: 1.65× its world share, 1 worksChemistryComputer Science: 0.76× its world share, 2 worksComputer ScienceEarth and Planetary Sciences: 0.20× its world share, 0 worksEarth and Planetary …Energy: 0.92× its world share, 0 worksEnergyEngineering: 0.05× its world share, 0 worksEngineeringEnvironmental Science: 0.15× its world share, 0 worksEnvironmental ScienceMathematics: 0.58× its world share, 0 worksMathematicsPhysics and Astronomy: 0.38× its world share, 0 worksPhysics and AstronomyHealth Professions: 0.06× its world share, 0 worksHealth ProfessionsMedicine: 1.00× its world share, 5 worksMedicineNursing: 0.95× its world share, 0 worksNursingArts and Humanities: 0.12× its world share, 0 worksArts and HumanitiesDecision Sciences: 1.02× its world share, 0 worksDecision SciencesEconomics, Econometrics and Finance: 2.17× its world share, 1 worksEconomics, Econometr…Social Sciences: 0.02× its world share, 0 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Biochemistry, Genetics and Molecular Biology, 9.2×. Every wedge is a field page.

All 20 fields, with their numbers
  1. Biochemistry, Genetics and Molecular Biology9.21×13 works
  2. Immunology and Microbiology7.69×2 works
  3. Pharmacology, Toxicology and Pharmaceutics2.61×0 works
  4. Economics, Econometrics and Finance2.17×1 works
  5. Neuroscience1.70×1 works
  6. Chemistry1.65×1 works
  7. Decision Sciences1.02×0 works
  8. Medicine1.00×5 works
  9. Nursing0.95×0 works
  10. Energy0.92×0 works
  11. Computer Science0.76×2 works
  12. Mathematics0.58×0 works
  13. Physics and Astronomy0.38×0 works
  14. Earth and Planetary Sciences0.20×0 works
  15. Environmental Science0.15×0 works
  16. Agricultural and Biological Sciences0.13×0 works
  17. Arts and Humanities0.12×0 works
  18. Health Professions0.06×0 works
  19. Engineering0.05×0 works
  20. Social Sciences0.02×0 works

Who are the top researchers at Open Targets?

Ranked on the quality score, Maya Ghoussaini and Mohd Anisul Karim lead among researchers whose main affiliation is Open Targets.

  1. 1 Maya Ghoussaini United Kingdom · #14,682 worldwide 15k citations · 118 works
  2. 2 Mohd Anisul Karim United Kingdom · #111,380 worldwide 36k citations · 53 works
All ranked researchers at Open Targets

What are the most cited papers from Open Targets?

The most cited paper from Open Targets is "COSMIC: the Catalogue Of Somatic Mutations In Cancer" (John G. Tate et al., 2018), with 5,379 citations. Next come "The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019" (4,675) and "Applications of machine learning in drug discovery and development" (3,274).

Most cited papers
#PaperReleasedCitations
1 COSMIC: the Catalogue Of Somatic Mutations In Cancer John G. Tate et al. · Nucleic Acids Research Open access 11 Oct 2018 5,379
2 The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 Annalisa Buniello et al. · Nucleic Acids Research Open access 25 Oct 2018 4,675
3 Applications of machine learning in drug discovery and development Jessica J. Vamathevan, Dominic A. Clark, Paul Czodrowski et al. · Nature Reviews Drug Discovery ReviewOpen access 11 Apr 2019 3,274
4 The Reactome Pathway Knowledgebase Antonio Fabregat et al. · Nucleic Acids Research Open access 26 Oct 2017 3,234
5 The reactome pathway knowledgebase 2022 Marc E. Gillespie et al. · Nucleic Acids Research Open access 13 Oct 2021 2,621
All 60 most cited papers, with filters and sorting

Which keywords describe research at Open Targets?

By fractional works in 2022-now, weighted toward what it does more of than the world: Gene Expression, Gene Set Enrichment Analysis, Protein-Protein Interaction Networks, Pharmacokinetics, RNA-Seq, Data Integration, Medicinal Chemistry and Genome Engineering.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 18 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 18 words, with their numbers
  1. Gene Expression3▲ 18×6 topics
  2. Machine Learning2▲ 2.4×5 topics
  3. Gene Set Enrichment Analysis2▲ 157×1 topic
  4. Pharmacokinetics2▲ 21×2 topics
  5. Protein-Protein Interaction Networks2▲ 157×1 topic
  6. Data Integration1▲ 31×3 topics
  7. RNA-Seq1▲ 46×2 topics
  8. Medicinal Chemistry1▲ 18×2 topics
  9. Cancer1▲ 3.4×5 topics
  10. Genome Engineering1▲ 76×1 topic
  11. Inflammation1▲ 2.1×10 topics
  12. Molecular Docking1▲ 38×1 topic
  13. RNA-Guided1▲ 76×1 topic
  14. Virtual Screening1▲ 52×1 topic
  15. Bioinformatics1▲ 35×3 topics
  16. Genetic Variation1▲ 20×3 topics
  17. Single-Cell1▲ 76×1 topic
  18. Transcriptomics1▲ 76×1 topic

Which research topics does Open Targets publish most on?

By volume in 2022-now: Bioinformatics and Genomic Networks, CRISPR and Genetic Engineering, Computational Drug Discovery Methods and Single-cell and spatial transcriptomics.

Bioinformatics and Genom…2Bioinformatics and Genomic Networks: 2 fractional worksCRISPR and Genetic Engin…1CRISPR and Genetic Engineering: 1 fractional worksComputational Drug Disco…1Computational Drug Discovery Methods: 1 fractional worksSingle-cell and spatial …1Single-cell and spatial transcriptomics: 1 fractional worksGenomics and Rare Diseases: 1 fractional worksGenetic Associations and Epidemiology: 1 fractional worksCancer Genomics and Diag…1Cancer Genomics and Diagnostics: 1 fractional worksImmune cells in cancer1Immune cells in cancer: 1 fractional worksCAR-T cell therapy research: 1 fractional worksCancer Immunotherapy and Biomarkers: 0 fractional works
Molecular BiologyComputational Theory and MathematicsGeneticsCancer Research2 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 Bioinformatics and Genomic Networks Molecular Biology 2 works
  2. 2 CRISPR and Genetic Engineering Molecular Biology 1 works
  3. 3 Computational Drug Discovery Methods Computational Theory and Mathematics 1 works
  4. 4 Single-cell and spatial transcriptomics Molecular Biology 1 works
  5. 5 Genomics and Rare Diseases Genetics 1 works
  6. 6 Genetic Associations and Epidemiology Genetics 1 works
  7. 7 Cancer Genomics and Diagnostics Cancer Research 1 works
  8. 8 Immune cells in cancer Immunology 1 works
  9. 9 CAR-T cell therapy research Oncology 1 works
  10. 10 Cancer Immunotherapy and Biomarkers Oncology 0 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available78.9%not open21.1%

World: 40% of research is openly available.

with international co-authors57.4%domestic only42.6%

World: 18% is written across borders.

How has Open Targets's research output changed?

Output in 2022-2025 was 48% higher than in 2018-2021.

still counting200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Open Targets as a percentage of every work published that year, 0.000082% in 2024.

still counting0.00010%0.00020%Open Targets0.000091% in 2025200020102020

Fractional works of Open Targets over all fractional works that year. How the balance of science has shifted.

Other research institutions in Cambridge

All research institutions in Cambridge

Research measures only: rankings here say nothing about teaching, admissions or student experience. Comparable institutions and collaboration partners have tabs of their own, above.

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