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Most cited papers from Research Triangle Park Foundation

What are the most cited papers from Research Triangle Park Foundation?

The most cited paper from Research Triangle Park Foundation is "Apoptosis: A Review of Programmed Cell Death" (Susan A. Elmore, 2007), with 13,911 citations. Next come "The International HapMap Project" (6,187) and "The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants" (4,843).

Showing 50 of 60 papers. Every paper with more than 1,301 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Apoptosis: A Review of Programmed Cell Death Susan A. Elmore · Toxicologic Pathology Open access Jun 2007 13,911
2 The International HapMap Project Richard A. Gibbs et al. · Nature Open access183 authors 18 Dec 2003 6,187
3 The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants Neil E. Klepeis, William C. Nelson, Wayne R. Ott et al. · Journal of Exposure Science & Environmental Epidemiology Open access Jul 2001 4,843
4 Structure validation by Cα geometry: ϕ,ψ and Cβ deviation Simon C. Lovell, Ian Davis, W.B. Arendall et al. · Proteins Structure Function and Bioinformatics 8 Jan 2003 4,652
5 Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β George G. J. M. Kuiper, Josephine Gabriela Lemmen, Bo Carlsson et al. · Endocrinology Oct 1998 4,209
6 The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds Martin van den Berg, Linda S. Birnbaum, Michael S. Denison et al. · Toxicological Sciences Open access 7 Jul 2006 3,805
7 Core outcome measures for chronic pain clinical trials: IMMPACT recommendations Robert H. Dworkin et al. · Pain 6 Nov 2004 3,789
8 An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ) Jürgen M. Lehmann, Linda B. Moore, Tracey A. Smith-Oliver et al. · Journal of Biological Chemistry Open access Jun 1995 3,648
9 The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation Mercedes Ricote, Andrew C. Li, Timothy Mark Willson et al. · Nature 1998 3,545
10 Core outcome domains for chronic pain clinical trials: IMMPACT recommendations Dennis C. Turk et al. · Pain 22 Sep 2003 3,518
11 Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations Robert H. Dworkin et al. · Journal of Pain Open access 13 Dec 2007 3,496
12 Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia Roger A. Fielding et al. · Journal of the American Medical Directors Association Open access 5 Mar 2011 3,319
13 Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research Susan D. Richardson, Michael J. Plewa, Elizabeth D. Wagner et al. · Mutation Research/Reviews in Mutation Research 13 Sep 2007 3,308
14 Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease PETER M. A. CALVERLEY, Julie A. Anderson, Bartolomé R. Celli et al. · New England Journal of Medicine Open access 21 Feb 2007 3,282
15 Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease John Robert Hurst, Jørgen Vestbo, Antonio R. Anzueto et al. · New England Journal of Medicine Open access 15 Sep 2010 3,024
16 A communal catalogue reveals Earth’s multiscale microbial diversity Luke Thompson et al. · Nature Open access303 authors 30 Oct 2017 2,968
17 Development of the asthma control test Robert A. Nathan, Christine A. Sorkness, Mark R. Kosinski et al. · Journal of Allergy and Clinical Immunology 2004 2,939
18 Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings Christopher S. Lau, Katherine Anitole, Colette S. Hodes et al. · Toxicological Sciences 22 May 2007 2,607
19 High cumulative incidence of uterine leiomyoma in black and white women: Ultrasound evidence Donna D. Baird, David B. Dunson, Michael C. Hill et al. · American Journal of Obstetrics and Gynecology 2003 2,469
20 The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids Andrew J. Brown et al. · Journal of Biological Chemistry Open access Mar 2003 2,411
21 Late-Onset Sepsis in Very Low Birth Weight Neonates: The Experience of the NICHD Neonatal Research Network Barbara J. Stoll, Nellie I. Hansen, Avroy A. Fanaroff et al. · PEDIATRICS Aug 2002 2,375
22 Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma Héctor Ortega, Mark C. Liu, Ian Douglas Pavord et al. · New England Journal of Medicine Open access 8 Sep 2014 2,339
23 Bile Acids: Natural Ligands for an Orphan Nuclear Receptor Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science 21 May 1999 2,273
24 Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial Ian Douglas Pavord, Stephanie Korn, Peter Hugo Howarth et al. · The Lancet Aug 2012 2,238
25 The Importance of Being Earnest: Validation is the Absolute Essential for Successful Application and Interpretation of QSPR Models Alexander Tropsha, Paola Gramatica, Vijay K. Gombar · QSAR & Combinatorial Science Apr 2003 2,196
26 QSAR Modeling: Where Have You Been? Where Are You Going To? Artem R Cherkasov, Eugene N. Muratov, Denis Fourches et al. · Journal of Medicinal Chemistry Open access 18 Dec 2013 2,178
27 Burden of Gastrointestinal Disease in the United States: 2012 Update Anne F. Peery, Evan S. Dellon, Jennifer Leigh Lund et al. · Gastroenterology Open access 8 Aug 2012 2,038
28 A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation Steven A. Kliewer, James M. Lenhard, Timothy Mark Willson et al. · Cell Open access Dec 1995 2,035
29 Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ Robert T. Nolte, G. Bruce Wisely, Stefan K. Westin et al. · Nature Sep 1998 1,965
30 An Integrated Risk Function for Estimating the Global Burden of Disease Attributable to Ambient Fine Particulate Matter Exposure Richard T. Burnett et al. · Environmental Health Perspectives Open access 11 Feb 2014 1,954
31 A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis Bryan J. Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell Open access Sep 2000 1,931
32 Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis Takeshi Inagaki, Mihwa Choi, Antonio Moschetta et al. · Cell Metabolism Open access Oct 2005 1,852
33 HLA-B*5701 Screening for Hypersensitivity to Abacavir Simon Alexander Mallal, Elizabeth Jane Phillips, Giampiero Carosi et al. · New England Journal of Medicine Open access 6 Feb 2008 1,847
34 MDS Cognitive Performance Scale(C) John N. Morris, Brant E. Fries, David R. Mehr et al. · Journal of Gerontology Jul 1994 1,836
35 Topological Persistence and Simplification Edelsbrunner, Letscher, Zomorodian · Discrete & Computational Geometry Open access Nov 2002 1,833
36 The PPARs: From Orphan Receptors to Drug Discovery Timothy Mark Willson, Peter J. Brown, Daniel D. Sternbach et al. · Journal of Medicinal Chemistry Open access Feb 2000 1,816
37 The support of human genetic evidence for approved drug indications Matthew R. Nelson, Hannah Tipney, Jeffery L. Painter et al. · Nature Genetics 29 Jun 2015 1,812
38 Computational topology an introduction Herbert Edelsbrunner, John Harer 2010 1,788
39 Estimating Global “Blue Carbon” Emissions from Conversion and Degradation of Vegetated Coastal Ecosystems Linwood H. Pendleton, Daniel C. Donato, Brian C. Murray et al. · PLoS ONE Open access 4 Sep 2012 1,768
40 Current methods of the U.S. Preventive Services Task Force Russell Harris, Mark Helfand, Steven H. Woolf et al. · American Journal of Preventive Medicine Apr 2001 1,744
41 Brominated flame retardants: cause for concern? Linda S. Birnbaum, Daniele F. Staskal · Environmental Health Perspectives Open access 17 Oct 2003 1,708
42 Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma Elisabeth H. Bel, Sally E. Wenzel, Philip J. Thompson et al. · New England Journal of Medicine 8 Sep 2014 1,674
43 Arsenic toxicity and potential mechanisms of action Michael F. Hughes · Toxicology Letters Jul 2002 1,670
44 Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia Willemijn J. Jansen et al. · JAMA Open access129 authors 19 May 2015 1,662
45 Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α Marcia L. Moss et al. · Nature Feb 1997 1,637
46 Genes mirror geography within Europe John Novembre, Toby Johnson, Katarzyna Bryc et al. · Nature Open access 31 Aug 2008 1,617
47 A Controlled Trial of Sustained-Release Bupropion, a Nicotine Patch, or Both for Smoking Cessation Douglas E. Jorenby, Scott James Leischow, Mitchell A. Nides et al. · New England Journal of Medicine Open access 4 Mar 1999 1,609
48 Refinement of the Coomassie blue method of protein quantitation Thomas Spector · Analytical Biochemistry May 1978 1,590
49 The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J�rgen Lehmann, David D. McKee, Mark A Watson et al. · Journal of Clinical Investigation Open access Sep 1998 1,582
50 An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell Open access 1998 1,555

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.