Most cited papers from Roche (Switzerland)

Roche (Switzerland)

What are the most cited papers from Roche (Switzerland)?

The most cited paper from Roche (Switzerland) is "2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative" (Daniel Aletaha et al., 2010), with 9,731 citations. Next come "Biological insights from 108 schizophrenia-associated genetic loci" (8,181) and "Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma" (7,547).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 59 papers. Every paper with more than 2,055 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative Daniel Aletaha et al. · Arthritis & Rheumatism Open access	10 Aug 2010	9,731
2	Biological insights from 108 schizophrenia-associated genetic loci Stephan Ripke et al. · Nature Open access297 authors	Jul 2014	8,181
3	Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma Richard S. Finn et al. · New England Journal of Medicine Open access	13 May 2020	7,547
4	Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial Yung‐Jue Bang, Eric Van Cutsem, Andrea Feyereislova et al. · The Lancet Open access	Aug 2010	7,405
5	Fluorine in Pharmaceuticals: Looking Beyond Intuition Klaus Müller, Christoph Faeh, François Diederich · Science	27 Sep 2007	6,622
6	Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection Michael Fried, Mitchell L. Shiffman, K. Rajender Reddy et al. · New England Journal of Medicine	25 Sep 2002	6,410
7	Elastic Properties of Lipid Bilayers: Theory and Possible Experiments W. Helfrich · Zeitschrift für Naturforschung C Open access	Dec 1973	6,290
8	Death Receptors: Signaling and Modulation Avi Ashkenazi, Vishva M. Dixit · Science	28 Aug 1998	5,896
9	The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses Gil Stelzer, Naomi Rosen, Inbar Plaschkes et al. · Current Protocols in Bioinformatics	Jun 2016	5,762
10	Elements of cancer immunity and the cancer–immune set point Daniel S. Chen, Ira Mellman · Nature	2017	5,520
11	Planck 2015 results Ade, PAR et al. · ORCA Online Research @Cardiff (Cardiff University) Open access261 authors	Oct 2016	5,452
12	Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Ewan Birney et al. · Nature Open access312 authors	Jun 2007	5,310
13	Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer Martine J Piccart et al. · New England Journal of Medicine Open access	20 Oct 2005	5,138
14	In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2 Lyubomir T. Vassilev, Binh Thanh Vu, Bradford J. Graves et al. · Science	5 Jan 2004	4,741
15	A simple and very efficient method for generating cDNA libraries Ueli Gubler, Beth J. Hoffman · Gene	Nov 1983	4,567
16	Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer Peter Schmid, Sylvia Adams, Hope S. Rugo et al. · New England Journal of Medicine Open access	20 Oct 2018	4,469
17	Cancer immunotherapy comes of age Ira Mellman, George Coukos, Glenn Dranoff · Nature Open access	20 Dec 2011	3,936
18	The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors	5 Feb 2020	3,854
19	Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden Zachary Rockow Chalmers et al. · Genome Medicine Open access	13 Apr 2017	3,800
20	Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial Jonathan E. Rosenberg et al. · The Lancet Open access	5 Mar 2016	3,762
21	Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene Napoleone Ferrara, Karen Carver-Moore, Helen Chen et al. · Nature	Apr 1996	3,673
22	Gravitational Waves and Gamma-Rays from a Binary Neutron Star Merger: GW170817 and GRB 170817A B. P. Abbott et al. · The Astrophysical Journal Letters Open access1,154 authors	16 Oct 2017	3,599
23	Identification and expression cloning of a leptin receptor, OB-R Louis A. Tartaglia, Marlene Dembski, Xun Weng et al. · Cell Open access	Dec 1995	3,513
24	The tomato genome sequence provides insights into fleshy fruit evolution Hideki Hirakawa et al. · Nature Open access271 authors	May 2012	3,442
25	Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors	5 Feb 2020	3,360
26	Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression eQTLGen et al. · Nature Genetics Open access218 authors	26 Apr 2018	3,347
27	Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell Open access	Aug 1997	3,170
28	Cryopyrin activates the inflammasome in response to toxins and ATP Sanjeev Mariathasan, David S. Weiss, Kim I. Newton et al. · Nature	11 Jan 2006	3,104
29	Two-sided markets: a progress report Jean-Charles Rochet, Jean Tirole · The RAND Journal of Economics	Sep 2006	3,075
30	Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice Dennis Huszar, Catherine A. Lynch, Victoria Fairchild-Huntress et al. · Cell Open access	1997	3,071
31	C-Reactive Protein and Other Circulating Markers of Inflammation in the Prediction of Coronary Heart Disease John Danesh, Jeremy G. Wheeler, Gideon Morris Hirschfield et al. · New England Journal of Medicine Open access	31 Mar 2004	2,970
32	Creatine and Creatinine Metabolism Markus Wyss, Rima F Kaddurah-Daouk · Physiological Reviews Review	Jul 2000	2,964
33	FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer Thierry Conroy et al. · New England Journal of Medicine Open access	19 Dec 2018	2,918
34	Mapping genomic loci implicates genes and synaptic biology in schizophrenia Vassily Vladimirovich Trubetskoy et al. · Nature Open access613 authors	8 Apr 2022	2,894
35	Severe Psoriasis – Oral Therapy with a New Retinoid Tove Fredriksson, U. Pettersson · Dermatologica	14 Oct 2009	2,758
36	GMAP: a genomic mapping and alignment program for mRNA and EST sequences Ting‐Di Wu, C.K. Watanabe · Computer applications in the biosciences Open access	22 Feb 2005	2,754
37	Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer Gϋnter von Minckwitz et al. · New England Journal of Medicine Open access	5 Dec 2018	2,689
38	Efficacy of B-Cell–Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis Jonathan Edwards, Leszek Szczepanski, Jacek Szechiński et al. · New England Journal of Medicine Open access	16 Jun 2004	2,640
39	Synthesis of Light-Emitting Conjugated Polymers for Applications in Electroluminescent Devices Andrew C. Grimsdale, Khai Leok Chan, Rainer E. Martin et al. · Chemical Reviews Review	19 Feb 2009	2,638
40	Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study Aurélien Marabelle et al. · The Lancet Oncology Open access	10 Sep 2020	2,600
41	Molecular mechanisms of mTOR-mediated translational control Xiaoju Max Ma, John Blenis · Nature Reviews Molecular Cell Biology Review	2 Apr 2009	2,595
42	Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer José Baselga, Javier Cortés, Sung‐Bae Kim et al. · New England Journal of Medicine Open access	7 Dec 2011	2,559
43	Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation Steven V. Ley, Andrew W. Thomas · Angewandte Chemie International Edition	11 Nov 2003	2,549
44	Alectinib versus Crizotinib in Untreated ALK -Positive Non–Small-Cell Lung Cancer Solange Peters, D. Ross Camidge, Alice Tsang Shaw et al. · New England Journal of Medicine Open access	6 Jun 2017	2,523
45	High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure J. P. Frat et al. · New England Journal of Medicine Open access	17 May 2015	2,419
46	Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial Luca Gianni, Tadeusz Pieńkowski, Young‐Hyuck Im et al. · The Lancet Oncology	10 Dec 2011	2,403
47	Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes Axel Ullrich, Jeffrey R. Bell, E. Y. Chen et al. · Nature	Feb 1985	2,273
48	Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells Napoleone Ferrara, William J. Henzel · Biochemical and Biophysical Research Communications	Jun 1989	2,269
49	Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial Bernard J. Escudier, Anna Pluzanska, P. Koralewski et al. · The Lancet	Dec 2007	2,234
50	Genome sequence of the Brown Norway rat yields insights into mammalian evolution Richard A. Gibbs et al. · Nature Open access248 authors	Apr 2004	2,224

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.