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Most cited papers from Toronto General Hospital

What are the most cited papers from Toronto General Hospital?

The most cited paper from Toronto General Hospital is "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (Clotilde Théry et al., 2018), with 11,535 citations. Next come "Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia" (4,592) and "Getting to the site of inflammation: the leukocyte adhesion cascade updated" (4,348).

Showing 50 of 59 papers. Every paper with more than 1,156 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
2 Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia David Matthew Garner, Marion P. Olmstead, Janet Polivy · International Journal of Eating Disorders 1983 4,592
3 Getting to the site of inflammation: the leukocyte adhesion cascade updated Klaus F. Ley, Carlo Laudanna, Myron I. Cybulsky et al. · Nature reviews. Immunology Review 24 Aug 2007 4,348
4 A Randomized Comparison of Coronary-Stent Placement and Balloon Angioplasty in the Treatment of Coronary Artery Disease David Lee Fischman et al. · New England Journal of Medicine Open access 25 Aug 1994 4,271
5 Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature Jul 1995 3,971
6 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
7 Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation William A. Zoghbi, David H Adams, Robert O. Bonow et al. · Journal of the American Society of Echocardiography 14 Mar 2017 3,570
8 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
9 Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock R. Phillip Dellinger, Jean M. Carlet, Henry Masur et al. · Intensive Care Medicine 3 Mar 2004 3,339
10 Recommendations for Conduct, Methodological Practices, and Reporting of Cost-effectiveness Analyses Gillian D Sanders, Peter J. Neumann, Anirban Basu et al. · JAMA Open access 13 Sep 2016 3,113
11 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference for the International Sepsis Definitions Conference, Mitchell M. Levy, Mitchell P. Fink et al. · Intensive Care Medicine 28 Mar 2003 2,908
12 How should we define health? Machteld Huber, J. André Knottnerus, L. Green et al. · BMJ Open access 26 Jul 2011 2,696
13 The development and initial validation of the systemic lupus international collaborating clinics/American college of rheumatology damage index for systemic lupus erythematosus Dafna D. Gladman et al. · Arthritis & Rheumatism Open access Mar 1996 2,609
14 Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper Matthias G. Friedrich, Udo P Sechtem, Jeanette Schulz‐Menger et al. · Journal of the American College of Cardiology Open access Apr 2009 2,526
15 Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome Alain Combes et al. · New England Journal of Medicine Open access 23 May 2018 2,451
16 International network of cancer genome projects Jennifer L. Jennings et al. · Nature Open access256 authors 13 Apr 2010 2,439
17 Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus Thierry Poynard, Patrick Marcellin, Samuel S. Lee et al. · The Lancet Oct 1998 2,335
18 Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma Roland P. H. Schmitz et al. · New England Journal of Medicine Open access 11 Apr 2018 2,325
19 Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS) Nuh N. Rahbari et al. · Surgery 15 Jan 2011 2,325
20 22q11.2 deletion syndrome Donna M. McDonald‐McGinn, Kathleen E. Sullivan, Bruno Marino et al. · Nature Reviews Disease Primers ReviewOpen access 18 Nov 2015 2,278
21 Updated Method Guidelines for Systematic Reviews in the Cochrane Collaboration Back Review Group Maurits W. van Tulder, Andréa Dompieri Furlan, Claire Bombardier et al. · Spine Review Jun 2003 2,218
22 The biology of incretin hormones Daniel J. Drucker · Cell Metabolism Open access Mar 2006 2,207
23 Parkinson's Disease Anthony E. Lang, Andrés M. Lozano · New England Journal of Medicine 8 Oct 1998 2,019
24 Bile leakage after hepatobiliary and pancreatic surgery: A definition and grading of severity by the International Study Group of Liver Surgery Moritz Koch et al. · Surgery 15 Feb 2011 2,011
25 Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence Terence J. Coderre, Joel D Katz, Anthony L. Vaccarino et al. · Pain Open access Mar 1993 1,999
26 Outcome of Heart Failure with Preserved Ejection Fraction in a Population-Based Study R. Sacha Bhatia, Jack V. Tu, Douglas S. Lee et al. · New England Journal of Medicine Open access 19 Jul 2006 1,979
27 Vasopressin versus Norepinephrine Infusion in Patients with Septic Shock James A. Russell, Keith R. Walley, Joel Singer et al. · New England Journal of Medicine Open access 27 Feb 2008 1,925
28 Empirical Studies Assessing the Quality of Health Information for Consumers on the World Wide Web Günther Eysenbach, john a. powell, Oliver Kuß et al. · JAMA 22 May 2002 1,917
29 Antenatal risk factors for postpartum depression: a synthesis of recent literature Emma Robertson, Sherry Lynn Grace, Tamara Wallington et al. · General Hospital Psychiatry Jul 2004 1,913
30 Diagnostic Performance of Coronary Angiography by 64-Row CT Julie M. Miller, Carlos Eduardo Rochitte, Marc Dewey et al. · New England Journal of Medicine 26 Nov 2008 1,824
31 2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease‐modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis Jasvinder A. Singh et al. · Arthritis Care & Research Open access 2 Apr 2012 1,806
32 Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study Michael Athanassios Gatzoulis, Seshadri Balaji, Steven A. Webber et al. · The Lancet Sep 2000 1,788
33 Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma Jordi Bruix, María Reig, Morris Sherman · Gastroenterology 12 Jan 2016 1,780
34 Injuries Involving the Epiphyseal Plate Robert B. Salter, William R. Harris · Journal of Bone and Joint Surgery Apr 1963 1,738
35 Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray Y. Ann Chen, Mathieu Lemire, Sanaa Choufani et al. · Epigenetics Open access 11 Jan 2013 1,738
36 Discrimination and Calibration of Clinical Prediction Models Ana Carolina Alba, Thomas Agoritsas, Michael W. Walsh et al. · JAMA 10 Oct 2017 1,716
37 An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome Eddy Fan et al. · American Journal of Respiratory and Critical Care Medicine May 2017 1,699
38 Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations Sonya A. MacParland et al. · Nature Communications Open access 16 Oct 2018 1,682
39 Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis Bradley J. Langford, Miranda M. So, Sumit Raybardhan et al. · Clinical Microbiology and Infection Open access 22 Jul 2020 1,653
40 Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms Charles H. Tator, Michael George Fehlings · Journal of neurosurgery Jul 1991 1,616
41 Myocarditis in Patients Treated With Immune Checkpoint Inhibitors Syed Amer Mahmood, Michael G. Fradley, Justine Vanessa Cohen et al. · Journal of the American College of Cardiology Open access 19 Mar 2018 1,603
42 DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts David Roulois, Helen Loo Yau, Rajat Singhania et al. · Cell Open access Aug 2015 1,574
43 VEGF Inhibition and Renal Thrombotic Microangiopathy Vera Eremina, J. Ashley Jefferson, Jolanta Kowalewska et al. · New England Journal of Medicine Open access 12 Mar 2008 1,514
44 Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial Kathy S. Albain, Ruth Swann, Valerie W. Rusch et al. · The Lancet Open access 25 Jul 2009 1,483
45 Probability of Cancer in Pulmonary Nodules Detected on First Screening CT Annette M. McWilliams et al. · New England Journal of Medicine Open access 4 Sep 2013 1,444
46 Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS) Tim J. P. Batchelor, Neil Rasburn, Etienne Abdelnour‐Berchtold et al. · European Journal of Cardio-Thoracic Surgery Open access 3 Aug 2018 1,391
47 Suggested standards for reporting on arterial aneurysms K.Wayne Johnston, Robert Bruce Rutherford, Martin David Tilson et al. · Journal of Vascular Surgery Mar 1991 1,386
48 Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus Hiddo J.L. Heerspink, Bruce A. Perkins, DAVID H. FITCHETT et al. · Circulation 29 Jul 2016 1,378
49 Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. Louis A. Tremblay, Franco Valenza, Sérgio Pinto Ribeiro et al. · Journal of Clinical Investigation Open access Mar 1997 1,337
50 Health related virtual communities and electronic support groups: systematic review of the effects of online peer to peer interactions Günther Eysenbach, john a. powell, Marina F Englesakis et al. · BMJ ReviewOpen access 13 May 2004 1,304

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.