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Most cited papers in Advanced Glycation End Products research

Advanced Glycation End Products research

What are the most cited papers in Advanced Glycation End Products research?

The most cited paper in Advanced Glycation End Products research is "Biochemistry and molecular cell biology of diabetic complications" (Michael Brownlee, 2001), with 9,153 citations. Next come "Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study" (9,131) and "Neuroinflammation in Alzheimer's disease" (6,318).

Showing 50 of 98 papers. Every paper with more than 1,028 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Biochemistry and molecular cell biology of diabetic complications Michael Brownlee · Nature 13 Dec 2001 9,153
2 Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study IRENE M. STRATTON · BMJ Open access 12 Aug 2000 9,131
3 Neuroinflammation in Alzheimer's disease Michael Thomas Heneka et al. · The Lancet Neurology Open access 16 Mar 2015 6,318
4 Oxidative Stress and Diabetic Complications Ferdinando Giacco, Michael Brownlee · Circulation Research Open access 28 Oct 2010 5,514
5 Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature Apr 2000 4,302
6 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Paola Scaffidi, Tom Misteli, Marco Emilio Bianchi · Nature 11 Jul 2002 4,239
7 Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Lyudmila V. Borovikova, Svetlana Ivanova, Minghuang Zhang et al. · Nature May 2000 4,235
8 Dietary Advanced Glycation End Products and Their Potential Role in Cardiometabolic Disease in Children Anshu Gupta, Jaime Uribarri · Hormone Research in Paediatrics Open access 2016 4,017
9 Role of Oxidative Stress in Development of Complications in Diabetes John Baynes · Diabetes Apr 1991 3,719
10 Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression Masahiro Nezu, Norio Suzuki, Masayuki P. Yamamoto · American Journal of Nephrology 2017 3,459
11 HMG-1 as a Late Mediator of Endotoxin Lethality in Mice Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science 9 Jul 1999 3,422
12 Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells Ying Yang, Shuping Li, Qiao Yang et al. · Cellular Physiology and Biochemistry Open access 2014 3,256
13 Diabetes, oxidative stress, and antioxidants: A review Alice C. Maritim, Ruth A. Sanders, J. B. Watkins · Journal of Biochemical and Molecular Toxicology 2003 3,140
14 Mechanisms of Diabetic Complications Josephine Maree Forbes, Mark Emmanuel Cooper · Physiological Reviews Review 2013 2,890
15 DAMPs, PAMPs and alarmins: all we need to know about danger Marco Emilio Bianchi · Journal of Leukocyte Biology 10 Oct 2006 2,790
16 A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress Daniele Del Rio, Amanda Janis Stewart, Nicoletta Pellegrini · Nutrition Metabolism and Cardiovascular Diseases 29 Jul 2005 2,741
17 Protein Oxidation and Aging Earl R. Stadtman · Science 28 Aug 1992 2,701
18 Advanced glycation end-products: a review Ravinder Singh, Anne E. Barden, Trevor Anthony Mori et al. · Diabetologia Open access 5 Feb 2001 2,606
19 The Beclin 1 network regulates autophagy and apoptosis Raehui Kang, Herbert J. Zeh, Michael T. Lotze et al. · Cell Death and Differentiation Open access 11 Feb 2011 2,537
20 High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal Michael T. Lotze, Kevin J. Tracey · Nature reviews. Immunology Review Apr 2005 2,533
21 Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications Jeffrey S. Flier, Lisa H. Underhill, Michael Brownlee et al. · New England Journal of Medicine 19 May 1988 2,526
22 Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes Louis Monnier, Emilie Mas, Christine Ginet et al. · JAMA 11 Apr 2006 2,484
23 Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. John Baynes, Suzanne R. Thorpe · Diabetes 1999 2,449
24 Advanced Glycation End Products Alison H. Goldin, Joshua A. Beckman, Ann Marie Schmidt et al. · Circulation 7 Aug 2006 2,265
25 Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux et al. · Endocrine Reviews Oct 2002 2,239
26 RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease Shi Du Yan, Xi Chen, Jin Fu et al. · Nature Aug 1996 2,013
27 Advanced oxidation protein products as a novel marker of oxidative stress in uremia Véronique Witko‐Sarsat, Miriam A. Friedlander, Chantal Capeillère‐Blandin et al. · Kidney International Open access May 1996 2,011
28 Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans Katherine Esposito, Francesco Nappo, Raffaele Marfella et al. · Circulation 14 Oct 2002 1,987
29 Free radical-mediated oxidation of free amino acids and amino acid residues in proteins Earl R. Stadtman, Rodney L. Levine · Amino Acids 29 Jul 2003 1,970
30 Oxidative Stress and Diabetic Vascular Complications Dario Giugliano, Antonio Ceriello, Giuseppe Paolisso · Diabetes Care Mar 1996 1,938
31 RAGE Mediates a Novel Proinflammatory Axis Marion A. Hofmann, Steven Drury, Caifeng Fu et al. · Cell Open access Jun 1999 1,871
32 Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method Satoh Kei · Clinica Chimica Acta Nov 1978 1,735
33 Biochemistry and pathology of radical-mediated protein oxidation Roger Thornton Dean, Shanlin Fu, Roland Stocker et al. · Biochemical Journal Open access 15 May 1997 1,697
34 Acrylamide from Maillard reaction products Richard H. Stadler, Imre Blank, Natalia Varga et al. · Nature Oct 2002 1,675
35 Diabetic Retinopathy David A. Antonetti, Ronald Klein, Thomas W. Gardner · New England Journal of Medicine 28 Mar 2012 1,633
36 Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss Ryan Yimeng Lee, Tien Yin Wong, Charumathi Sabanayagam · Eye and Vision Open access 29 Sep 2015 1,598
37 Diabetes mellitus and oxidative stress—A concise review Asmat Ullah, Abad Khan, Khan Ismail · Saudi Pharmaceutical Journal Open access 5 Apr 2015 1,589
38 Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein Jong Sung Park, Daiva Svetkauskaite, Qianbin He et al. · Journal of Biological Chemistry Open access Feb 2004 1,570
39 Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. Michael P. Neeper, Ann Marie Schmidt, Jerold Brett et al. · Journal of Biological Chemistry Open access Jul 1992 1,545
40 Advanced Glycation End Products and Diabetic Complications Varun Parkash Singh, Anjana Bali, Nirmal Singh et al. · Korean Journal of Physiology and Pharmacology Open access 2014 1,525
41 Long-Term Complications of Diabetes Mellitus David M. Nathan · New England Journal of Medicine 10 Jun 1993 1,515
42 Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction? Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux et al. · Diabetes Open access 2003 1,487
43 Neuroinflammation: friend and foe for ischemic stroke Richard L. Jayaraj, Sheikh Azimullah, Rami Beiram et al. · Journal of Neuroinflammation Open access 10 Jul 2019 1,476
44 What is oxidative stress? D. J. Betteridge · Metabolism Feb 2000 1,458
45 Advanced glycation endproducts—role in pathology of diabetic complications Nessar Ahmed · Diabetes Research and Clinical Practice 4 Nov 2004 1,456
46 HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection Ulf Andersson, Kevin J. Tracey · Annual Review of Immunology ReviewOpen access Mar 2011 1,442
47 HMGB1 and RAGE in Inflammation and Cancer Gary P. Sims, Daniel C. Rowe, Svend T. Rietdijk et al. · Annual Review of Immunology Review Mar 2010 1,440
48 RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain Rashid Deane et al. · Nature Medicine 13 Jun 2003 1,429
49 High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes Ulf Andersson, Haichao Wang, Karin Palmblad et al. · The Journal of Experimental Medicine Open access 21 Aug 2000 1,421
50 Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE Jane Y. Tian et al. · Nature Immunology 8 Apr 2007 1,375

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.